메뉴 건너뛰기




Volumn 85, Issue 2, 2007, Pages 342-350

Inhibitors of glutamate transport modulate distinct patterns in brain metabolism

Author keywords

13C NMR spectroscopy; GLAST; GLT; Glutamate receptors; Glutamate transport; Metabolomics

Indexed keywords

(2 CARBOXYCYCLOPROPYL)GLYCINE; 4 AMINOBUTYRIC ACID; ASPARTIC ACID DERIVATIVE; DEXTRO LEVO THREO BETA BENZYLOXYASPARTATE; DICARBOXYLIC ACID DERIVATIVE; DIHYDROKAINIC ACID; EXCITATORY AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTAMINE; GLYCINE DERIVATIVE; LACTIC ACID; LEVO ANTI ENDO 3,4 METHANOPYROLIDINE DICARBOXYLATE; LEVO PYRROLIDINE 2,4 DICARBOXYLATE; PYRUVIC ACID; UNCLASSIFIED DRUG;

EID: 33846859313     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21108     Document Type: Article
Times cited : (20)

References (66)
  • 1
    • 23644445510 scopus 로고    scopus 로고
    • Alagarsamy S, Saugstad J, Warren L, Mansuy IM, Gereau RW IV, Conn PJ. 2005. NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin. Neuropharmacol 49:135-145.
    • Alagarsamy S, Saugstad J, Warren L, Mansuy IM, Gereau RW IV, Conn PJ. 2005. NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin. Neuropharmacol 49:135-145.
  • 3
    • 0034332480 scopus 로고    scopus 로고
    • Activation of mGluR5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of subthalamic nucleus
    • Awad H, Huber GW, Smith Y, Levey AI, Conn PJ. 2000. Activation of mGluR5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of subthalamic nucleus. J Neurosci 20:7871-7879.
    • (2000) J Neurosci , vol.20 , pp. 7871-7879
    • Awad, H.1    Huber, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 5
    • 0036516328 scopus 로고    scopus 로고
    • +-dependent transport of acidic amino acids in the mammalian central nervous system
    • +-dependent transport of acidic amino acids in the mammalian central nervous system. Biological Pharm Bull 25:291-301.
    • (2002) Biological Pharm Bull , vol.25 , pp. 291-301
    • Balcar, V.J.1
  • 6
    • 0032780415 scopus 로고    scopus 로고
    • Forty years of amino acid transmission in the brain
    • Bennett MR, Balcar VJ. 1999. Forty years of amino acid transmission in the brain. Neurochem Int 35:269-280.
    • (1999) Neurochem Int , vol.35 , pp. 269-280
    • Bennett, M.R.1    Balcar, V.J.2
  • 7
    • 0035503323 scopus 로고    scopus 로고
    • Physiological genomics of antidepressant targets: Keeping the periphery in mind
    • Blakely RD. 2001. Physiological genomics of antidepressant targets: keeping the periphery in mind. J Neurosci 21:8319-8323.
    • (2001) J Neurosci , vol.21 , pp. 8319-8323
    • Blakely, R.D.1
  • 8
    • 0029815360 scopus 로고    scopus 로고
    • The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures
    • Blitzblau R, Gupta S, Djali S, Robinson MR, Roseberg PA. 1996. The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures. Eur J Neurosci 8:1840-1852.
    • (1996) Eur J Neurosci , vol.8 , pp. 1840-1852
    • Blitzblau, R.1    Gupta, S.2    Djali, S.3    Robinson, M.R.4    Roseberg, P.A.5
  • 9
    • 23844450692 scopus 로고    scopus 로고
    • The excitatory amino acid transporter: Pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes
    • Bridges RJ, Esslinger CS. 2005. The excitatory amino acid transporter: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes. Pharmacol Ther 107:271-285.
    • (2005) Pharmacol Ther , vol.107 , pp. 271-285
    • Bridges, R.J.1    Esslinger, C.S.2
  • 10
    • 0032937403 scopus 로고    scopus 로고
    • A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system
    • Bridges RJ, Kavanaugh MP, Chamberlin AR. 1999. A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system. Curr Pharm Des 5:363-379.
    • (1999) Curr Pharm Des , vol.5 , pp. 363-379
    • Bridges, R.J.1    Kavanaugh, M.P.2    Chamberlin, A.R.3
  • 11
    • 0037088930 scopus 로고    scopus 로고
    • Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain
    • Chen W, Aoki C, Mahadomrongkul V, Gruber CE, Wang GJ, Blitzblau R, Irwin N, Rosenberg PA. 2002. Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain. J Neurosci 22:2142-2152.
    • (2002) J Neurosci , vol.22 , pp. 2142-2152
    • Chen, W.1    Aoki, C.2    Mahadomrongkul, V.3    Gruber, C.E.4    Wang, G.J.5    Blitzblau, R.6    Irwin, N.7    Rosenberg, P.A.8
  • 12
    • 0036618260 scopus 로고    scopus 로고
    • Activity-dependent recruitment of extrasynaptic NMDA receptor activation at an AMPA receptor-only synapse
    • Clark BA, Cull-Candy S. 2002. Activity-dependent recruitment of extrasynaptic NMDA receptor activation at an AMPA receptor-only synapse. J Neurosci 22:4428-4436.
    • (2002) J Neurosci , vol.22 , pp. 4428-4436
    • Clark, B.A.1    Cull-Candy, S.2
  • 13
    • 0031918486 scopus 로고    scopus 로고
    • EAAC1, a high-affinity glutamate transporter, is localized to astrocytes and GABAergic neurons besides pyramidal cells in the rat cerebral cortex
    • Conti F, DeBiasi S, Minelli A, Rothstein JD, Melone M. 1998. EAAC1, a high-affinity glutamate transporter, is localized to astrocytes and GABAergic neurons besides pyramidal cells in the rat cerebral cortex. Cereb Cortex 8:108-116.
    • (1998) Cereb Cortex , vol.8 , pp. 108-116
    • Conti, F.1    DeBiasi, S.2    Minelli, A.3    Rothstein, J.D.4    Melone, M.5
  • 14
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC. 2001. Glutamate uptake. Prog Neurobiol 35:1-105.
    • (2001) Prog Neurobiol , vol.35 , pp. 1-105
    • Danbolt, N.C.1
  • 15
    • 0035503349 scopus 로고    scopus 로고
    • Neuronal glutamate transporters limit activation of NMDA receptors by neurotransmitter spillover on CA1 pyramidal cells
    • Diamond JS. 2001. Neuronal glutamate transporters limit activation of NMDA receptors by neurotransmitter spillover on CA1 pyramidal cells. J Neurosci 21:8328-8338.
    • (2001) J Neurosci , vol.21 , pp. 8328-8338
    • Diamond, J.S.1
  • 18
    • 0021330769 scopus 로고
    • Glutamate - a neurotransmitter in mammalian brain
    • Fonnum F. 1984. Glutamate - a neurotransmitter in mammalian brain. J Neurochem 42:1-11.
    • (1984) J Neurochem , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 19
    • 0001526389 scopus 로고
    • Cyclopropane amino acids from aesculus and blighia
    • Fowden L, Smith A. 1969. Cyclopropane amino acids from aesculus and blighia. Phytochemistry 8:437-438.
    • (1969) Phytochemistry , vol.8 , pp. 437-438
    • Fowden, L.1    Smith, A.2
  • 20
    • 33645877686 scopus 로고    scopus 로고
    • High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of a glutamine/neutral amino acid transporters ASCT2 in human fetal astrocytes
    • Gegelashvili M, Rodriguez-Kern A, Pirozhkova I, Zhang J, Sung L, Gegelashvili G. 2006. High-affinity glutamate transporter GLAST/EAAT1 regulates cell surface expression of a glutamine/neutral amino acid transporters ASCT2 in human fetal astrocytes. Neurochem Int 48:611-615.
    • (2006) Neurochem Int , vol.48 , pp. 611-615
    • Gegelashvili, M.1    Rodriguez-Kern, A.2    Pirozhkova, I.3    Zhang, J.4    Sung, L.5    Gegelashvili, G.6
  • 21
    • 33846890036 scopus 로고    scopus 로고
    • D. Phil. Thesis Oxford: The University of Oxford
    • 13C NMR. D. Phil. Thesis Oxford: The University of Oxford.
    • (1997) 13C NMR
    • Griffin, J.L.1
  • 23
    • 0031741880 scopus 로고    scopus 로고
    • Excitatory amino acid synthesis in hypoxic brain slices: Does alanine act as a substrate for glutamate production in hypoxia?
    • Griffin JL, Rae C, Dixon RM, Radda GK, Matthews PM. 1998. Excitatory amino acid synthesis in hypoxic brain slices: does alanine act as a substrate for glutamate production in hypoxia? J Neurochem 71:2477-2486.
    • (1998) J Neurochem , vol.71 , pp. 2477-2486
    • Griffin, J.L.1    Rae, C.2    Dixon, R.M.3    Radda, G.K.4    Matthews, P.M.5
  • 26
    • 2442699087 scopus 로고    scopus 로고
    • Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons
    • Huang YHH, Sinha SR, Tanaka K, Rothstein JD, Bergles DE. 2004. Astrocyte glutamate transporters regulate metabotropic glutamate receptor-mediated excitation of hippocampal interneurons. J Neurosci 24:4551-4559.
    • (2004) J Neurosci , vol.24 , pp. 4551-4559
    • Huang, Y.H.H.1    Sinha, S.R.2    Tanaka, K.3    Rothstein, J.D.4    Bergles, D.E.5
  • 28
    • 0033953525 scopus 로고    scopus 로고
    • Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex
    • Kidd FL, Isaac JTR. 2000. Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex. Neuropharmacology 39:725-732.
    • (2000) Neuropharmacology , vol.39 , pp. 725-732
    • Kidd, F.L.1    Isaac, J.T.R.2
  • 30
    • 58149365834 scopus 로고
    • Adiabatic pulses for wideband inversion and broadband decoupling
    • Kupce E, Freeman R. 1995. Adiabatic pulses for wideband inversion and broadband decoupling. J Magn Res A 115:273-276.
    • (1995) J Magn Res A , vol.115 , pp. 273-276
    • Kupce, E.1    Freeman, R.2
  • 31
    • 0032194950 scopus 로고    scopus 로고
    • The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain
    • Lehre KP, Danbolt NC. 1998. The number of glutamate transporter subtype molecules at glutamatergic synapses: Chemical and stereological quantification in young adult rat brain. J Neurosci 18:8751-8757.
    • (1998) J Neurosci , vol.18 , pp. 8751-8757
    • Lehre, K.P.1    Danbolt, N.C.2
  • 32
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat-brain - quantitative and immunocytochemical observations
    • Lehre KP, Levy LM, Ottersen OP, Stormmathisen J, Danbolt NC. 1995. Differential expression of two glial glutamate transporters in the rat-brain - quantitative and immunocytochemical observations. J Neurosci 15:1835-1853.
    • (1995) J Neurosci , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3    Stormmathisen, J.4    Danbolt, N.C.5
  • 33
    • 1842524064 scopus 로고    scopus 로고
    • Glutamate transporters: Animal models to neurologic disease
    • Maragakis NJ, Rothstein JD. 2004. Glutamate transporters: animal models to neurologic disease. Neurobiol Dis 15:461-473.
    • (2004) Neurobiol Dis , vol.15 , pp. 461-473
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 34
    • 13544263608 scopus 로고    scopus 로고
    • Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics
    • Matute C, Melone M, Vallejo-Illarramendi A, Conti F. 2005. Increased expression of the astrocytic glutamate transporter GLT-1 in the prefrontal cortex of schizophrenics. Glia 49:451-455.
    • (2005) Glia , vol.49 , pp. 451-455
    • Matute, C.1    Melone, M.2    Vallejo-Illarramendi, A.3    Conti, F.4
  • 36
    • 0032401003 scopus 로고    scopus 로고
    • Glutamate transport in cultures from developing avian cerebellum: Presence of GLT-1 immunoreactivity in Purkinje neurons
    • Meaney JA, Balcar VJ, Rothstein JD, Jeffrey PL. 1998. Glutamate transport in cultures from developing avian cerebellum: presence of GLT-1 immunoreactivity in Purkinje neurons. J Neurosci Res 54:595-603.
    • (1998) J Neurosci Res , vol.54 , pp. 595-603
    • Meaney, J.A.1    Balcar, V.J.2    Rothstein, J.D.3    Jeffrey, P.L.4
  • 39
    • 0035814443 scopus 로고    scopus 로고
    • The glial glutamate transporter GLT-1 is localized both in the vicinity of and at distance from axon terminals in the rat cerebral cortex
    • Minelli A, Barbaresi P, Reimer RJ, Edwards RH, Conti F. 2001. The glial glutamate transporter GLT-1 is localized both in the vicinity of and at distance from axon terminals in the rat cerebral cortex. Neuroscience 108:51-59.
    • (2001) Neuroscience , vol.108 , pp. 51-59
    • Minelli, A.1    Barbaresi, P.2    Reimer, R.J.3    Edwards, R.H.4    Conti, F.5
  • 40
    • 20444371553 scopus 로고    scopus 로고
    • Differential effects of the substrate inhibitor L-trans-pyrrolidine-2,4- dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta- benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat brain in vivo
    • Montiel T, Camacho A, Estrada-Sanchez AM, Massieu L. 2005. Differential effects of the substrate inhibitor L-trans-pyrrolidine-2,4- dicarboxylate (PDC) and the non-substrate inhibitor DL-threo-beta- benzyloxyaspartate (DL-TBOA) of glutamate transporters on neuronal damage and extracellular amino acid levels in rat brain in vivo. Neuroscience 133:667-678.
    • (2005) Neuroscience , vol.133 , pp. 667-678
    • Montiel, T.1    Camacho, A.2    Estrada-Sanchez, A.M.3    Massieu, L.4
  • 41
    • 1842734876 scopus 로고    scopus 로고
    • Glutamatergic chemical transmission: Look! here, there, and anywhere
    • Moriyama Y, Yamamoto A. 2004. Glutamatergic chemical transmission: look! here, there, and anywhere. J Biochem 135:155-163.
    • (2004) J Biochem , vol.135 , pp. 155-163
    • Moriyama, Y.1    Yamamoto, A.2
  • 43
    • 0036129245 scopus 로고    scopus 로고
    • Moussa CE-H, Mitrovic AD, Vandenberg RJ, Provis T, Rae C, Bubb WA, Balcar VJ. 2002. Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1′S, 2′R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy. Neurochem Res 27:27-35.
    • Moussa CE-H, Mitrovic AD, Vandenberg RJ, Provis T, Rae C, Bubb WA, Balcar VJ. 2002. Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1′S, 2′R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy. Neurochem Res 27:27-35.
  • 44
    • 0027216795 scopus 로고
    • 2S,3S,4R)-2- (carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate
    • Nakamura Y, Kataoka K, Ishida M, Shinozaki H. 1993. (2S,3S,4R)-2- (carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate. Neuropharmacology 32:833-837.
    • (1993) Neuropharmacology , vol.32 , pp. 833-837
    • Nakamura, Y.1    Kataoka, K.2    Ishida, M.3    Shinozaki, H.4
  • 47
    • 0036129209 scopus 로고    scopus 로고
    • Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: New evidence on substrates and blockers in excitotoxicity
    • O'Shea RD, Fodera MV, Aprico K, Dehnes Y, Danbolt NC, Crawford D, Beart PM. 2002. Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: new evidence on substrates and blockers in excitotoxicity. Neurochemical Res 27:5-13.
    • (2002) Neurochemical Res , vol.27 , pp. 5-13
    • O'Shea, R.D.1    Fodera, M.V.2    Aprico, K.3    Dehnes, Y.4    Danbolt, N.C.5    Crawford, D.6    Beart, P.M.7
  • 48
    • 0006450818 scopus 로고
    • 3,4-Cyclopropylglutamates as conformationally restricted agonists of the NMDA receptor
    • Pellicciari R, Natalini B, Marinozzi M, Selvi L, Chiori C, Monahan JB, Lanthorn TH, Snyder JP, editors, New York: Alan Liss Inc. pp
    • Pellicciari R, Natalini B, Marinozzi M, Selvi L, Chiori C, Monahan JB, Lanthorn TH, Snyder JP, editors. 1988. 3,4-Cyclopropylglutamates as conformationally restricted agonists of the NMDA receptor. In: Frontiers in excitatory amino acid research. New York: Alan Liss Inc. pp 67-70.
    • (1988) Frontiers in excitatory amino acid research , pp. 67-70
  • 49
    • 0030898586 scopus 로고    scopus 로고
    • Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones
    • Pisani A, Calabresi P, Centonze D, Bernardi G. 1997. Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones. Br J Pharmacol 120:1007-1014.
    • (1997) Br J Pharmacol , vol.120 , pp. 1007-1014
    • Pisani, A.1    Calabresi, P.2    Centonze, D.3    Bernardi, G.4
  • 51
    • 0037390782 scopus 로고    scopus 로고
    • Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: Further evidence for metabolic compartmentation
    • Rae C, Hare N, Bubb WA, McEwan SR, Bröer A, McQuillan JA, Balcar VJ, Conigrave AD, Bröer S. 2003. Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. J Neurochem 85:503-514.
    • (2003) J Neurochem , vol.85 , pp. 503-514
    • Rae, C.1    Hare, N.2    Bubb, W.A.3    McEwan, S.R.4    Bröer, A.5    McQuillan, J.A.6    Balcar, V.J.7    Conigrave, A.D.8    Bröer, S.9
  • 52
    • 0034319176 scopus 로고    scopus 로고
    • Strategies for studies of potentially neurotoxic mechanisms involving deficient transport of L-glutamate: Antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pigs brain slices
    • Rae C, Lawrance ML, Dias LS, Provis T, Bubb WA, Balcar VJ. 2000. Strategies for studies of potentially neurotoxic mechanisms involving deficient transport of L-glutamate: antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pigs brain slices. Brain Res Bull 53:373-381.
    • (2000) Brain Res Bull , vol.53 , pp. 373-381
    • Rae, C.1    Lawrance, M.L.2    Dias, L.S.3    Provis, T.4    Bubb, W.A.5    Balcar, V.J.6
  • 53
    • 13244279636 scopus 로고    scopus 로고
    • Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: A 13C NMR spectroscopy and metabolomic study
    • Rae C, Moussa CE-H, Griffin JL, Bubb WA, Wallis T, Balcar VJ. 2005b. Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study. J Neurochem 92:405-416.
    • (2005) J Neurochem , vol.92 , pp. 405-416
    • Rae, C.1    Moussa, C.E.-H.2    Griffin, J.L.3    Bubb, W.A.4    Wallis, T.5    Balcar, V.J.6
  • 54
    • 33746525514 scopus 로고    scopus 로고
    • A metabolomic approach to ionotropic glutamate receptor subtype function: A nuclear magnetic resonance in vitro investigation
    • Rae C, Moussa CE-H, Griffin JL, Parekh SB, Bubb WA, Hunt NH, Balcar VJ. 2006. A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation. J Cereb Blood Flow Metab 26:1005-1017.
    • (2006) J Cereb Blood Flow Metab , vol.26 , pp. 1005-1017
    • Rae, C.1    Moussa, C.E.-H.2    Griffin, J.L.3    Parekh, S.B.4    Bubb, W.A.5    Hunt, N.H.6    Balcar, V.J.7
  • 56
    • 3042556105 scopus 로고    scopus 로고
    • Molecular pharmacology of glutamate transporters, EAATs and VGLUTs
    • Shigeri Y, Seal RP, Shimamoto K. 2004. Molecular pharmacology of glutamate transporters, EAATs and VGLUTs. Brain Res Rev 45:250-265.
    • (2004) Brain Res Rev , vol.45 , pp. 250-265
    • Shigeri, Y.1    Seal, R.P.2    Shimamoto, K.3
  • 57
    • 0025797354 scopus 로고
    • Synthesis of 4 diastereomeric L-2-(carboxycyclopropyl)glycines - conformationally constrained L-glutamate analogs
    • Shimamoto K, Ishida M, Shinozaki H, Ohfune Y. 1991. Synthesis of 4 diastereomeric L-2-(carboxycyclopropyl)glycines - conformationally constrained L-glutamate analogs. J Org Chem 56:4167-4176.
    • (1991) J Org Chem , vol.56 , pp. 4167-4176
    • Shimamoto, K.1    Ishida, M.2    Shinozaki, H.3    Ohfune, Y.4
  • 58
    • 0000842606 scopus 로고    scopus 로고
    • A phase-cycling algorithm for reducing sidebands in adiabatic decoupling
    • Skinner TE, Bendall MR. 1997. A phase-cycling algorithm for reducing sidebands in adiabatic decoupling. J Magn Reson 124:474-478.
    • (1997) J Magn Reson , vol.124 , pp. 474-478
    • Skinner, T.E.1    Bendall, M.R.2
  • 60
    • 1042279664 scopus 로고    scopus 로고
    • Cloning, transport properties, and differential localization of two splice variants of GLT-1 in the rat CNS: Implications for CNS glutamate homeostasis
    • Sullivan R, Rauen T, Fischer F, Wiessner M, Grewer C, Bicho A, Pow DV. 2004. Cloning, transport properties, and differential localization of two splice variants of GLT-1 in the rat CNS: implications for CNS glutamate homeostasis. Glia 45:155-169.
    • (2004) Glia , vol.45 , pp. 155-169
    • Sullivan, R.1    Rauen, T.2    Fischer, F.3    Wiessner, M.4    Grewer, C.5    Bicho, A.6    Pow, D.V.7
  • 61
    • 0029885882 scopus 로고    scopus 로고
    • Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS
    • Sutherland ML, Delaney TA, Noebels JL. 1996. Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. J Neurosci 16:2191-2207.
    • (1996) J Neurosci , vol.16 , pp. 2191-2207
    • Sutherland, M.L.1    Delaney, T.A.2    Noebels, J.L.3
  • 62
    • 0028076043 scopus 로고    scopus 로고
    • Thomsen C, Hansen L, Suzdak P. 1994. L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a. J Neurochem 63:2038-2047.
    • Thomsen C, Hansen L, Suzdak P. 1994. L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a. J Neurochem 63:2038-2047.
  • 63
    • 0030946093 scopus 로고    scopus 로고
    • Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters EAAT1 and EAAT2
    • Vandenberg RJ, Mitrovic AD, Chebib M, Balcar VJ, Johnston GAR. 1997. Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters EAAT1 and EAAT2. Mol Pharmacol 51:809-815.
    • (1997) Mol Pharmacol , vol.51 , pp. 809-815
    • Vandenberg, R.J.1    Mitrovic, A.D.2    Chebib, M.3    Balcar, V.J.4    Johnston, G.A.R.5
  • 64
    • 0029891078 scopus 로고    scopus 로고
    • Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures
    • Velasco I, Tapia R, Massieu L. 1996. Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures. J Neurosci Res 44:551-561.
    • (1996) J Neurosci Res , vol.44 , pp. 551-561
    • Velasco, I.1    Tapia, R.2    Massieu, L.3
  • 66
    • 84989076126 scopus 로고
    • Gradient selection in inverse heteronuclear correlation spectroscopy
    • Willker W, Leibfritz D, Kerssebaum R, Bermel W. 1993. Gradient selection in inverse heteronuclear correlation spectroscopy. Magn Reson Chem 31:287-292.
    • (1993) Magn Reson Chem , vol.31 , pp. 287-292
    • Willker, W.1    Leibfritz, D.2    Kerssebaum, R.3    Bermel, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.