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Volumn 34, Issue 11, 2014, Pages 1911-1928

Negative elongation factor is required for the maintenance of proviral latency but does not induce promoter-proximal pausing of RNA polymerase II on the HIV long terminal repeat

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; RNA POLYMERASE II; TUMOR NECROSIS FACTOR ALPHA;

EID: 84897958511     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01013-13     Document Type: Article
Times cited : (89)

References (98)
  • 2
    • 46049096099 scopus 로고    scopus 로고
    • Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection.
    • Shen L, Siliciano RF. 2008. Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection. J. Allergy Clin. Immunol. 122:22-28. http://dx.doi.org/10.1016/j.jaci.2008.05.033.
    • (2008) J. Allergy Clin. Immunol. , vol.122 , pp. 22-28
    • Shen, L.1    Siliciano, R.F.2
  • 7
    • 0033515521 scopus 로고    scopus 로고
    • NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation.
    • Yamaguchi Y, Takagi T, Wada T, Yano K, Furuya A, Sugimoto S, Hasegawa J, Handa H. 1999. NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation. Cell 97:41-51. http://dx.doi.org/10.1016/S0092-8674(00)80713-8.
    • (1999) Cell , vol.97 , pp. 41-51
    • Yamaguchi, Y.1    Takagi, T.2    Wada, T.3    Yano, K.4    Furuya, A.5    Sugimoto, S.6    Hasegawa, J.7    Handa, H.8
  • 8
    • 0032548918 scopus 로고    scopus 로고
    • A novel cdk9-associated c-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop specific binding to TAR RNA.
    • Wei P, Garber ME, Fang S-M, Fischer WH, Jones KA. 1998. A novel cdk9-associated c-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop specific binding to TAR RNA. Cell 92:451-462. http://dx.doi.org/10.1016/S0092-8674(00)80939-3.
    • (1998) Cell , vol.92 , pp. 451-462
    • Wei, P.1    Garber, M.E.2    Fang, S.-M.3    Fischer, W.H.4    Jones, K.A.5
  • 9
    • 0036275982 scopus 로고    scopus 로고
    • Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tatactivated transcriptional elongation.
    • Kim YK, Bourgeois CF, Isel C, Churcher MJ, Karn J. 2002. Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tatactivated transcriptional elongation. Mol. Cell. Biol. 22:4622-4637. http://dx.doi.org/10.1128/MCB.22.13.4622-4637.2002.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4622-4637
    • Kim, Y.K.1    Bourgeois, C.F.2    Isel, C.3    Churcher, M.J.4    Karn, J.5
  • 10
    • 0036150085 scopus 로고    scopus 로고
    • Spt5 cooperates with Tat by preventing premature RNA release at terminator sequences.
    • Bourgeois CF, Kim YK, Churcher MJ, West MJ, Karn J. 2002. Spt5 cooperates with Tat by preventing premature RNA release at terminator sequences. Mol. Cell. Biol. 22:1079-1093. http://dx.doi.org/10.1128/MCB.22.4.1079-1093.2002.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1079-1093
    • Bourgeois, C.F.1    Kim, Y.K.2    Churcher, M.J.3    West, M.J.4    Karn, J.5
  • 11
    • 0342748478 scopus 로고    scopus 로고
    • Domains in the SPT5 protein that modulate its transcriptional regulatory properties.
    • Ivanov D, Kwak YT, Guo J, Gaynor RB. 2000. Domains in the SPT5 protein that modulate its transcriptional regulatory properties. Mol. Cell. Biol. 20: 2970-2983. http://dx.doi.org/10.1128/MCB.20.9.2970-2983.2000.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2970-2983
    • Ivanov, D.1    Kwak, Y.T.2    Guo, J.3    Gaynor, R.B.4
  • 12
    • 0346095303 scopus 로고    scopus 로고
    • Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element.
    • Fujinaga K, Irwin D, Huang Y, Taube R, Kurosu T, Peterlin BM. 2004. Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element. Mol. Cell. Biol. 24:787-795. http://dx.doi.org/10.1128/MCB.24.2.787-795.2004.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 787-795
    • Fujinaga, K.1    Irwin, D.2    Huang, Y.3    Taube, R.4    Kurosu, T.5    Peterlin, B.M.6
  • 13
    • 77951959240 scopus 로고    scopus 로고
    • HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.
    • He N, Liu M, Hsu J, Xue Y, Chou S, Burlingame A, Krogan NJ, Alber T, Zhou Q. 2010. HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription. Mol. Cell 38:428-438. http://dx.doi.org/10.1016/j.molcel.2010.04.013.
    • (2010) Mol. Cell , vol.38 , pp. 428-438
    • He, N.1    Liu, M.2    Hsu, J.3    Xue, Y.4    Chou, S.5    Burlingame, A.6    Krogan, N.J.7    Alber, T.8    Zhou, Q.9
  • 14
    • 75949126139 scopus 로고    scopus 로고
    • AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
    • Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A. 2010. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol. Cell 37:429-437. http://dx.doi.org/10.1016/j.molcel.2010.01.026.
    • (2010) Mol. Cell , vol.37 , pp. 429-437
    • Lin, C.1    Smith, E.R.2    Takahashi, H.3    Lai, K.C.4    Martin-Brown, S.5    Florens, L.6    Washburn, M.P.7    Conaway, J.W.8    Conaway, R.C.9    Shilatifard, A.10
  • 15
    • 77951954237 scopus 로고    scopus 로고
    • HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
    • Sobhian B, Laguette N, Yatim A, Nakamura M, Levy Y, Kiernan R, Benkirane M. 2010. HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP. Mol. Cell 38:439-451. http://dx.doi.org/10.1016/j.molcel.2010.04.012.
    • (2010) Mol. Cell , vol.38 , pp. 439-451
    • Sobhian, B.1    Laguette, N.2    Yatim, A.3    Nakamura, M.4    Levy, Y.5    Kiernan, R.6    Benkirane, M.7
  • 16
    • 68049129695 scopus 로고    scopus 로고
    • Stochastic gene expression as a molecular switch for viral latency
    • Singh A, Weinberger LS. 2009. Stochastic gene expression as a molecular switch for viral latency. Curr. Opin. Microbiol. 12:460-466. http://dx.doi.org/10.1016/j.mib.2009.06.016.
    • (2009) Curr. Opin. Microbiol. , vol.12 , pp. 460-466
    • Singh, A.1    Weinberger, L.S.2
  • 17
    • 22744441386 scopus 로고    scopus 로고
    • Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1Tat fluctuations drive phenotypic diversity
    • Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV. 2005. Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1Tat fluctuations drive phenotypic diversity. Cell 122:169-182. http://dx.doi.org/10.1016/j.cell.2005.06.006.
    • (2005) Cell , vol.122 , pp. 169-182
    • Weinberger, L.S.1    Burnett, J.C.2    Toettcher, J.E.3    Arkin, A.P.4    Schaffer, D.V.5
  • 19
    • 80052287096 scopus 로고    scopus 로고
    • Epigenetic silencing of HIV-1 by the histone H3 lysine 27 NELF Maintains HIV Latency methyltransferase enhancer of zeste 2 (EZH2)
    • Friedman J, Cho WK, Chu CK, Keedy KS, Archin NM, Margolis DM, Karn J. 2011. Epigenetic silencing of HIV-1 by the histone H3 lysine 27 NELF Maintains HIV Latency methyltransferase enhancer of zeste 2 (EZH2). J. Virol. 85:9078-9089.http://dx.doi.org/10.1128/JVI.00836-11.
    • (2011) J. Virol. , vol.85 , pp. 9078-9089
    • Friedman, J.1    Cho, W.K.2    Chu, C.K.3    Keedy, K.S.4    Archin, N.M.5    Margolis, D.M.6    Karn, J.7
  • 20
    • 65349193781 scopus 로고    scopus 로고
    • A limited group of class I histone deacetylases act to repress human immunodeficiency virus type-1 expression
    • Keedy KS, Archin NM, Gates AT, Espeseth A, Hazuda DJ, Margolis DM. 2009. A limited group of class I histone deacetylases act to repress human immunodeficiency virus type-1 expression. J. Virol. 83:4749-4756. http://dx.doi.org/10.1128/JVI.02585-08.
    • (2009) J. Virol. , vol.83 , pp. 4749-4756
    • Keedy, K.S.1    Archin, N.M.2    Gates, A.T.3    Espeseth, A.4    Hazuda, D.J.5    Margolis, D.M.6
  • 21
    • 57349090221 scopus 로고    scopus 로고
    • Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency
    • Pearson R, Kim YK, Hokello J, Lassen K, Friedman J, Tyagi M, Karn J.2008. Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the progressive entry of HIV into latency. J. Virol. 82:12291-12303. http://dx.doi.org/10.1128/JVI.01383-08.
    • (2008) J. Virol. , vol.82 , pp. 12291-12303
    • Pearson, R.1    Kim, Y.K.2    Hokello, J.3    Lassen, K.4    Friedman, J.5    Tyagi, M.6    Karn, J.7
  • 23
    • 67650925025 scopus 로고    scopus 로고
    • Epigenetic regulation of HIV-1 latency by cytosine methylation
    • Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E. 2009. Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS Pathog.5:e1000495. http://dx.doi.org/10.1371/journal.ppat.1000495.
    • (2009) PLoS Pathog. , vol.5
    • Kauder, S.E.1    Bosque, A.2    Lindqvist, A.3    Planelles, V.4    Verdin, E.5
  • 25
    • 48649089113 scopus 로고    scopus 로고
    • Transcriptional interference antagonizes proviral gene expression to promote HIV latency
    • Lenasi T, Contreras X, Peterlin BM. 2008. Transcriptional interference antagonizes proviral gene expression to promote HIV latency. Cell Host Microbe 4:123-133. http://dx.doi.org/10.1016/j.chom.2008.05.016.
    • (2008) Cell Host Microbe , vol.4 , pp. 123-133
    • Lenasi, T.1    Contreras, X.2    Peterlin, B.M.3
  • 28
    • 59449101108 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Blood 113:58-65. http://dx.doi.org/10.1182/blood-2008-07-168393.
    • (2009) Blood , vol.113 , pp. 58-65
    • Bosque, A.1    Planelles, V.2
  • 29
    • 0030939152 scopus 로고    scopus 로고
    • The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells
    • Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP. 1997. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity 6:235-244. http://dx.doi.org/10.1016/S1074-7613(00)80326-X.
    • (1997) Immunity , vol.6 , pp. 235-244
    • Kinoshita, S.1    Su, L.2    Amano, M.3    Timmerman, L.A.4    Kaneshima, H.5    Nolan, G.P.6
  • 30
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel G, Baltimore DA. 1987. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326:711-713. http://dx.doi.org/10.1038/326711a0.
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.A.2
  • 31
    • 0032542282 scopus 로고    scopus 로고
    • Upregulation of cyclin T1/CDK9 complexes during T cell activation
    • Garriga J, Peng J, Parreno M, Price DH, Henderson EE, Grana X. 1998.Upregulation of cyclin T1/CDK9 complexes during T cell activation. Oncogene 17:3093-3102. http://dx.doi.org/10.1038/sj.onc.1202548.
    • (1998) Oncogene , vol.17 , pp. 3093-3102
    • Garriga, J.1    Peng, J.2    Parreno, M.3    Price, D.H.4    Henderson, E.E.5    Grana, X.6
  • 32
    • 0035158637 scopus 로고    scopus 로고
    • + T lymphocytes by combination of cytokines
    • + T lymphocytes by combination of cytokines. J. Virol. 75:11336-11343. http://dx.doi.org/10.1128/JVI.75.23.11336-11343.2001.
    • (2001) J. Virol. , vol.75 , pp. 11336-11343
    • Ghose, R.1    Liou, L.Y.2    Herrmann, C.H.3    Rice, A.P.4
  • 33
    • 0036839206 scopus 로고    scopus 로고
    • Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function
    • Liou LY, Herrmann CH, Rice AP. 2002. Transient induction of cyclin T1 during human macrophage differentiation regulates human immunodeficiency virus type 1 Tat transactivation function. J. Virol. 76:10579-10587. http://dx.doi.org/10.1128/JVI.76.21.10579-10587.2002.
    • (2002) J. Virol. , vol.76 , pp. 10579-10587
    • Liou, L.Y.1    Herrmann, C.H.2    Rice, A.P.3
  • 34
    • 84883708671 scopus 로고    scopus 로고
    • NELF coordinates RNA polymerase II pausing, premature termination and chromatin remodeling to regulate HIV transcription
    • Natarajan M, Schiralli-Lester GM, Lee C, Missra A, Wasserman GA, Steffen M, Gilmour DS, Henderson AJ. 2013. NELF coordinates RNA polymerase II pausing, premature termination and chromatin remodeling to regulate HIV transcription. J. Biol. Chem. 288:25995-26003. http://dx.doi.org/10.1074/jbc. M113.496489.
    • (2013) J. Biol. Chem. , vol.288 , pp. 25995-26003
    • Natarajan, M.1    Schiralli-Lester, G.M.2    Lee, C.3    Missra, A.4    Wasserman, G.A.5    Steffen, M.6    Gilmour, D.S.7    Henderson, A.J.8
  • 37
    • 34547850648 scopus 로고    scopus 로고
    • Manipulation of P-TEFb control machinery by HIV: recruitment of PTEFb from the large form by Tat and binding of HEXIM1 to TAR
    • Sedore SC, Byers SA, Biglione S, Price JP, Maury WJ, Price DH. 2007. Manipulation of P-TEFb control machinery by HIV: recruitment of PTEFb from the large form by Tat and binding of HEXIM1 to TAR. Nucleic Acids Res. 35:4347-4358. http://dx.doi.org/10.1093/nar/gkm443.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4347-4358
    • Sedore, S.C.1    Byers, S.A.2    Biglione, S.3    Price, J.P.4    Maury, W.J.5    Price, D.H.6
  • 38
    • 0242361319 scopus 로고    scopus 로고
    • Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA
    • Yik JH, Chen R, Nishimura R, Jennings JL, Link AJ, Zhou Q. 2003. Inhibition of P-TEFb (CDK9/cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA. Mol. Cell 12:971-982. http://dx.doi.org/10.1016/S1097-2765(03)00388-5.
    • (2003) Mol. Cell , vol.12 , pp. 971-982
    • Yik, J.H.1    Chen, R.2    Nishimura, R.3    Jennings, J.L.4    Link, A.J.5    Zhou, Q.6
  • 39
    • 0028301838 scopus 로고
    • Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts
    • Adams M, Sharmeen L, Kimpton J, Romeo JM, Garcia JV, Peterlin BM, Groudine M, Emerman M. 1994. Cellular latency in human immunodeficiency virus-infected individuals with high CD4 levels can be detected by the presence of promoter-proximal transcripts. Proc. Natl. Acad. Sci. U.S.A. 91:3862-3866. http://dx.doi.org/10.1073/pnas.91.9.3862.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 3862-3866
    • Adams, M.1    Sharmeen, L.2    Kimpton, J.3    Romeo, J.M.4    Garcia, J.V.5    Peterlin, B.M.6    Groudine, M.7    Emerman, M.8
  • 40
    • 0035918157 scopus 로고    scopus 로고
    • DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation
    • Ping Y-H, Rana TM. 2001. DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation. J. Biol. Chem. 276:12951-12958. http://dx.doi.org/10.1074/jbc. M006130200.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12951-12958
    • Ping, Y.-H.1    Rana, T.M.2
  • 41
    • 0025602656 scopus 로고
    • The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from variousmRNAand snRNA promoters
    • Ratnasabapathy R, Sheldon M, Johal L, Hernandez N. 1990. The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from variousmRNAand snRNA promoters. Genes Dev. 4:2061-2074. http://dx.doi.org/10.1101/gad.4.12a.2061.
    • (1990) Genes Dev. , vol.4 , pp. 2061-2074
    • Ratnasabapathy, R.1    Sheldon, M.2    Johal, L.3    Hernandez, N.4
  • 42
    • 34447122581 scopus 로고    scopus 로고
    • Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex
    • Zhang Z, Klatt A, Gilmour DS, Henderson AJ. 2007. Negative elongation factor NELF represses human immunodeficiency virus transcription by pausing the RNA polymerase II complex. J. Biol. Chem. 282:16981-16988. http://dx.doi.org/10.1074/jbc. M610688200.
    • (2007) J. Biol. Chem. , vol.282 , pp. 16981-16988
    • Zhang, Z.1    Klatt, A.2    Gilmour, D.S.3    Henderson, A.J.4
  • 43
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. 2002. A system for stable expression of short interfering RNAs in mammalian cells. Science 296: 550-553. http://dx.doi.org/10.1126/science.1068999.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 44
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz M, Trono D. 2003. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol. 77:8957-8961. http://dx.doi.org/10.1128/JVI.77.16.8957-8951.2003.
    • (2003) J. Virol. , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 45
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. 1996. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272:263-267. http://dx.doi.org/10.1126/science.272.5259.263.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8
  • 46
    • 79960342414 scopus 로고    scopus 로고
    • T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway
    • Kim YK, Mbonye U, Hokello J, Karn J. 2011. T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway. J. Mol. Biol. 410: 896-916. http://dx.doi.org/10.1016/j.jmb.2011.03.054.
    • (2011) J. Mol. Biol. , vol.410 , pp. 896-916
    • Kim, Y.K.1    Mbonye, U.2    Hokello, J.3    Karn, J.4
  • 47
    • 77953313393 scopus 로고    scopus 로고
    • + cells is due to epigenetic transcriptional silencing and PTEFb restriction
    • + cells is due to epigenetic transcriptional silencing and PTEFb restriction. J. Virol. 84:6425-6437. http://dx.doi.org/10.1128/JVI.01519-09.
    • (2010) J. Virol. , vol.84 , pp. 6425-6437
    • Tyagi, M.1    Pearson, R.J.2    Karn, J.3
  • 48
    • 46149108345 scopus 로고    scopus 로고
    • Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci
    • Petesch SJ, Lis JT. 2008. Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci. Cell 134:74-84. http://dx.doi.org/10.1016/j.cell.2008.05.029.
    • (2008) Cell , vol.134 , pp. 74-84
    • Petesch, S.J.1    Lis, J.T.2
  • 49
    • 67649834440 scopus 로고    scopus 로고
    • ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions
    • Schmidt D, Wilson MD, Spyrou C, Brown GD, Hadfield J, Odom DT. 2009. ChIP-seq: using high-throughput sequencing to discover protein-DNA interactions. Methods 48:240-248. http://dx.doi.org/10.1016/j.ymeth.2009.03.001.
    • (2009) Methods , vol.48 , pp. 240-248
    • Schmidt, D.1    Wilson, M.D.2    Spyrou, C.3    Brown, G.D.4    Hadfield, J.5    Odom, D.T.6
  • 50
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memoryefficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL. 2009. Ultrafast and memoryefficient alignment of short DNA sequences to the human genome. Genome Biol. 10:R25. http://dx.doi.org/10.1186/gb-2009-10-3-r25.
    • (2009) Genome Biol. , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 54
    • 0031931047 scopus 로고    scopus 로고
    • Mutations in the Tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line
    • Emiliani S, Fischle W, Ott M, van Lint C, Amella CA, Verdin E. 1998. Mutations in the Tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line. J. Virol. 72:1666-1670.
    • (1998) J. Virol. , vol.72 , pp. 1666-1670
    • Emiliani, S.1    Fischle, W.2    Ott, M.3    van Lint, C.4    Amella, C.A.5    Verdin, E.6
  • 56
    • 34247552158 scopus 로고    scopus 로고
    • NELF interacts with CBC and participates in 3= end processing of replication-dependent histone mRNAs
    • Narita T, Yung TM, Yamamoto J, Tsuboi Y, Tanabe H, Tanaka K, Yamaguchi Y, Handa H. 2007. NELF interacts with CBC and participates in 3= end processing of replication-dependent histone mRNAs. Mol. Cell 26:349-365. http://dx.doi.org/10.1016/j.molcel.2007.04.011.
    • (2007) Mol. Cell , vol.26 , pp. 349-365
    • Narita, T.1    Yung, T.M.2    Yamamoto, J.3    Tsuboi, Y.4    Tanabe, H.5    Tanaka, K.6    Yamaguchi, Y.7    Handa, H.8
  • 57
    • 33747605357 scopus 로고    scopus 로고
    • Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency
    • Kim YK, Bourgeois CF, Pearson R, Tyagi M, West MJ, Wong J, Wu SY, Chiang CM, Karn J. 2006. Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency. EMBO J. 25: 3596-3604. http://dx.doi.org/10.1038/sj.emboj.7601248.
    • (2006) EMBO J. , vol.25 , pp. 3596-3604
    • Kim, Y.K.1    Bourgeois, C.F.2    Pearson, R.3    Tyagi, M.4    West, M.J.5    Wong, J.6    Wu, S.Y.7    Chiang, C.M.8    Karn, J.9
  • 58
    • 34249810678 scopus 로고    scopus 로고
    • Sustained induction of NF-kB is required for efficient expression of latent human immunodeficiency virus type 1
    • Williams SA, Kwon H, Chen LF, Greene WC. 2007. Sustained induction of NF-kB is required for efficient expression of latent human immunodeficiency virus type 1. J. Virol. 81:6043-6056. http://dx.doi.org/10.1128/JVI.02074-06.
    • (2007) J. Virol. , vol.81 , pp. 6043-6056
    • Williams, S.A.1    Kwon, H.2    Chen, L.F.3    Greene, W.C.4
  • 59
    • 59249086373 scopus 로고    scopus 로고
    • Control of stochastic gene expression by host factors at the HIV promoter
    • Burnett JC, Miller-Jensen K, Shah PS, Arkin AP, Schaffer DV. 2009. Control of stochastic gene expression by host factors at the HIV promoter. PLoS Pathog. 5:e1000260. http://dx.doi.org/10.1371/journal.ppat.1000260.
    • (2009) PLoS Pathog. , vol.5
    • Burnett, J.C.1    Miller-Jensen, K.2    Shah, P.S.3    Arkin, A.P.4    Schaffer, D.V.5
  • 60
    • 33846360341 scopus 로고    scopus 로고
    • An HIV feedback resistor: autoregulatory circuit deactivator and noise buffer
    • Weinberger LS, Shenk T. 2007. An HIV feedback resistor: autoregulatory circuit deactivator and noise buffer. PLoS Biol. 5:e9. http://dx.doi.org/10.1371/journal.pbio.0050009.
    • (2007) PLoS Biol. , vol.5
    • Weinberger, L.S.1    Shenk, T.2
  • 61
    • 77954383344 scopus 로고    scopus 로고
    • RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
    • D'Orso I, Frankel AD. 2010. RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation. Nat. Struct. Mol. Biol. 17:815-821. http://dx.doi.org/10.1038/nsmb.1827.
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 815-821
    • D'Orso, I.1    Frankel, A.D.2
  • 62
    • 0037841763 scopus 로고    scopus 로고
    • Transcription start regions in the human genome are favored targets for MLV integration
    • Wu X, Li Y, Crise B, Burgess SM. 2003. Transcription start regions in the human genome are favored targets for MLV integration. Science 300: 1749-1751. http://dx.doi.org/10.1126/science.1083413.
    • (2003) Science , vol.300 , pp. 1749-1751
    • Wu, X.1    Li, Y.2    Crise, B.3    Burgess, S.M.4
  • 63
    • 79952605355 scopus 로고    scopus 로고
    • Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency
    • Gallastegui E, Millan-Zambrano G, Terme JM, Chavez S, Jordan A. Chromatin reassembly factors are involved in transcriptional interference promoting HIV latency. J. Virol. 85:3187-3202. http://dx.doi.org/10.1128/JVI.01920-10.
    • J. Virol. , vol.85 , pp. 3187-3202
    • Gallastegui, E.1    Millan-Zambrano, G.2    Terme, J.M.3    Chavez, S.4    Jordan, A.5
  • 64
    • 0029919356 scopus 로고    scopus 로고
    • Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
    • Van Lint C, Emiliani S, Ott M, Verdin E. 1996. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 15:1112-1120.
    • (1996) EMBO J. , vol.15 , pp. 1112-1120
    • Van Lint, C.1    Emiliani, S.2    Ott, M.3    Verdin, E.4
  • 65
    • 82455219436 scopus 로고    scopus 로고
    • Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency
    • Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T. 2011. Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. PLoS Biol. 9:e1001206. http://dx.doi.org/10.1371/journal.pbio.1001206.
    • (2011) PLoS Biol. , vol.9
    • Rafati, H.1    Parra, M.2    Hakre, S.3    Moshkin, Y.4    Verdin, E.5    Mahmoudi, T.6
  • 67
    • 70849107088 scopus 로고    scopus 로고
    • Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling
    • Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I. 2009. Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling. Proc. Natl. Acad. Sci. U. S. A. 106:18207-18212. http://dx.doi.org/10.1073/pnas.0910177106.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 18207-18212
    • Adelman, K.1    Kennedy, M.A.2    Nechaev, S.3    Gilchrist, D.A.4    Muse, G.W.5    Chinenov, Y.6    Rogatsky, I.7
  • 68
    • 84871699564 scopus 로고    scopus 로고
    • Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans
    • Adelman K, Lis JT. 2012. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans. Nat. Rev. Genet. 13:720-731. http://dx.doi.org/10.1038/nrg3293.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 720-731
    • Adelman, K.1    Lis, J.T.2
  • 71
    • 78149477660 scopus 로고    scopus 로고
    • Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation
    • Gilchrist DA, Dos Santos G, Fargo DC, Xie B, Gao Y, Li L, Adelman K. Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation. Cell 143:540-551. http://dx.doi.org/10.1016/j.cell.2010.10.004.
    • Cell , vol.143 , pp. 540-551
    • Gilchrist, D.A.1    Dos Santos, G.2    Fargo, D.C.3    Xie, B.4    Gao, Y.5    Li, L.6    Adelman, K.7
  • 72
  • 73
    • 47549090254 scopus 로고    scopus 로고
    • NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
    • Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, Li L, Gilmour DS, Adelman K. 2008. NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly. Genes Dev. 22:1921-1933. http://dx.doi.org/10.1101/gad.1643208.
    • (2008) Genes Dev. , vol.22 , pp. 1921-1933
    • Gilchrist, D.A.1    Nechaev, S.2    Lee, C.3    Ghosh, S.K.4    Collins, J.B.5    Li, L.6    Gilmour, D.S.7    Adelman, K.8
  • 74
    • 0037446948 scopus 로고    scopus 로고
    • HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
    • Jordan A, Bisgrove D, Verdin E. 2003. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro. EMBO J. 22:1868-1877. http://dx.doi.org/10.1093/emboj/cdg188.
    • (2003) EMBO J. , vol.22 , pp. 1868-1877
    • Jordan, A.1    Bisgrove, D.2    Verdin, E.3
  • 75
    • 0030610544 scopus 로고    scopus 로고
    • The kB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth
    • Chen BK, Feinberg MB, Baltimore D. 1997. The kB sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth. J. Virol. 71:5495-5504.
    • (1997) J. Virol. , vol.71 , pp. 5495-5504
    • Chen, B.K.1    Feinberg, M.B.2    Baltimore, D.3
  • 76
    • 84856484784 scopus 로고    scopus 로고
    • Control of HIV latency by epigenetic and non-epigenetic mechanisms
    • Mbonye U, Karn J. 2011. Control of HIV latency by epigenetic and non-epigenetic mechanisms. Curr. HIV Res. 9:554-567. http://dx.doi.org/10.2174/157016211798998736.
    • (2011) Curr. HIV Res. , vol.9 , pp. 554-567
    • Mbonye, U.1    Karn, J.2
  • 77
    • 0027446368 scopus 로고
    • Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs
    • Sheldon M, Ratnasabapathy R, Hernandez N. 1993. Characterization of the inducer of short transcripts, a human immunodeficiency virus type 1 transcriptional element that activates the synthesis of short RNAs. Mol. Cell. Biol. 13:1251-1263.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1251-1263
    • Sheldon, M.1    Ratnasabapathy, R.2    Hernandez, N.3
  • 78
    • 0036232590 scopus 로고    scopus 로고
    • Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA
    • Yamaguchi Y, Inukai N, Narita T, Wada T, Handa H. 2002. Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA. Mol. Cell. Biol. 22:2918-2927. http://dx.doi.org/10.1128/MCB.22.9.2918-2927.2002.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2918-2927
    • Yamaguchi, Y.1    Inukai, N.2    Narita, T.3    Wada, T.4    Handa, H.5
  • 79
    • 38149020517 scopus 로고    scopus 로고
    • Transcription- dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals
    • Perkins KJ, Lusic M, Mitar I, Giacca M, Proudfoot NJ. 2008. Transcription- dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals. Mol. Cell 29:56-68. http://dx.doi.org/10.1016/j.molcel.2007.11.030.
    • (2008) Mol. Cell , vol.29 , pp. 56-68
    • Perkins, K.J.1    Lusic, M.2    Mitar, I.3    Giacca, M.4    Proudfoot, N.J.5
  • 81
    • 0033583290 scopus 로고    scopus 로고
    • Structure and function of the human transcription elongation factor DSIF
    • Yamaguchi Y, Wada T, Watanabe D, Takagi T, Hasegawa J, Handa H. Structure and function of the human transcription elongation factor DSIF. J. Biol. Chem. 274:8085-8092. http://dx.doi.org/10.1074/jbc.274.12.8085.
    • J. Biol. Chem. , vol.274 , pp. 8085-8092
    • Yamaguchi, Y.1    Wada, T.2    Watanabe, D.3    Takagi, T.4    Hasegawa, J.5    Handa, H.6
  • 82
    • 56649106687 scopus 로고    scopus 로고
    • Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay
    • Cheng B, Price DH. 2008. Analysis of factor interactions with RNA polymerase II elongation complexes using a new electrophoretic mobility shift assay. Nucleic Acids Res. 36:e135. http://dx.doi.org/10.1093/nar/gkn630.
    • (2008) Nucleic Acids Res. , vol.36
    • Cheng, B.1    Price, D.H.2
  • 83
    • 77954889072 scopus 로고    scopus 로고
    • Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex
    • Missra A, Gilmour DS. 2010. Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex. Proc. Natl. Acad. Sci. U. S. A. 107:11301-11306. http://dx.doi.org/10.1073/pnas.1000681107.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 11301-11306
    • Missra, A.1    Gilmour, D.S.2
  • 84
    • 84871889026 scopus 로고    scopus 로고
    • Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA
    • D'Orso I, Jang GM, Pastuszak AW, Faust TB, Quezada E, Booth DS, Frankel AD. 2012. Transition step during assembly of HIV Tat:P-TEFb transcription complexes and transfer to TAR RNA. Mol. Cell. Biol. 32: 4780-4793. http://dx.doi.org/10.1128/MCB.00206-12.
    • (2012) Mol. Cell. Biol. , vol.32 , pp. 4780-4793
    • D'Orso, I.1    Jang, G.M.2    Pastuszak, A.W.3    Faust, T.B.4    Quezada, E.5    Booth, D.S.6    Frankel, A.D.7
  • 85
    • 84877721757 scopus 로고    scopus 로고
    • SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase
    • Ji X, Zhou Y, Pandit S, Huang J, Li H, Lin CY, Xiao R, Burge CB, Fu XD. 2013. SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell 153:855-868. http://dx.doi.org/10.1016/j.cell.2013.04.028.
    • (2013) Cell , vol.153 , pp. 855-868
    • Ji, X.1    Zhou, Y.2    Pandit, S.3    Huang, J.4    Li, H.5    Lin, C.Y.6    Xiao, R.7    Burge, C.B.8    Fu, X.D.9
  • 86
    • 57849109058 scopus 로고    scopus 로고
    • Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
    • Core LJ, Waterfall JJ, Lis JT. 2008. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 322:1845-1848. http://dx.doi.org/10.1126/science.1162228.
    • (2008) Science , vol.322 , pp. 1845-1848
    • Core, L.J.1    Waterfall, J.J.2    Lis, J.T.3
  • 87
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. 2007. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130:77-88. http://dx.doi.org/10.1016/j.cell.2007.05.042.
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 89
    • 45849129033 scopus 로고    scopus 로고
    • Promoter-proximal Pol II: when stalling speeds things up
    • Nechaev S, Adelman K. 2008. Promoter-proximal Pol II: when stalling speeds things up. Cell Cycle 7:1539-1544. http://dx.doi.org/10.4161/cc.7.11.6006.
    • (2008) Cell Cycle , vol.7 , pp. 1539-1544
    • Nechaev, S.1    Adelman, K.2
  • 91
    • 36549013619 scopus 로고    scopus 로고
    • RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo
    • Zeitlinger J, Stark A, Kellis M, Hong JW, Nechaev S, Adelman K, Levine M, Young RA. 2007. RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo. Nat. Genet. 39:1512-1516. http://dx.doi.org/10.1038/ng.2007.26.
    • (2007) Nat. Genet. , vol.39 , pp. 1512-1516
    • Zeitlinger, J.1    Stark, A.2    Kellis, M.3    Hong, J.W.4    Nechaev, S.5    Adelman, K.6    Levine, M.7    Young, R.A.8
  • 92
    • 41349094797 scopus 로고    scopus 로고
    • Transcription regulation through promoterproximal pausing of RNA polymerase II
    • Core LJ, Lis JT. 2008. Transcription regulation through promoterproximal pausing of RNA polymerase II. Science 319:1791-1792. http://dx.doi.org/10.1126/science.1150843.
    • (2008) Science , vol.319 , pp. 1791-1792
    • Core, L.J.1    Lis, J.T.2
  • 93
    • 0035834647 scopus 로고    scopus 로고
    • A highly purified RNA polymerase II elongation control system
    • Renner DB, Yamaguchi Y, Wada T, Handa H, Price DH. 2001. A highly purified RNA polymerase II elongation control system. J. Biol. Chem. 276:42601-42609. http://dx.doi.org/10.1074/jbc. M104967200.
    • (2001) J. Biol. Chem. , vol.276 , pp. 42601-42609
    • Renner, D.B.1    Yamaguchi, Y.2    Wada, T.3    Handa, H.4    Price, D.H.5


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