Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 9, 2009, Pages 4368-4378

  Maeda, Tadao ^a   Maeda, Akiko ^a   Casadesus, Gemma ^b   Palczewski, Krzysztof ^a   Margaron, Philippe ^c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c QLT Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EYE PROTEIN; RETINAL PIGMENT EPITHELIUM SPECIFIC 65 PROTEIN; RETINOL ACETATE; SOYBEAN OIL; UNCLASSIFIED DRUG; CARRIER PROTEIN; DRUG DERIVATIVE; DRUG VEHICLE; PRODRUG; RETINOID; RETINOL; RPE65 PROTEIN, MOUSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ABSORPTION; DRUG MEGADOSE; DRUG METABOLISM; DRUG TOLERABILITY; ELECTRORETINOGRAPHY; FEMALE; LEBER CONGENITAL AMAUROSIS; MALE; MORPHOLOGY; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETINOPATHY; SINGLE DRUG DOSE; VISION; ANIMAL; BLINDNESS; C57BL MOUSE; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHOTOSTIMULATION; RADIATION EXPOSURE; RETINA; RETINA DEGENERATION; VEHICLES;

ANIMALS; BEHAVIOR, ANIMAL; BLINDNESS; CARRIER PROTEINS; ELECTRORETINOGRAPHY; EYE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOTIC STIMULATION; PRODRUGS; RETINA; RETINAL DEGENERATION; RETINOIDS; SOYBEAN OIL; VEHICLES; VITAMIN A;

EID: 70349247885     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3700     Document Type: Article

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