PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses

Thrombosis and Haemostasis

Volumn 111, Issue 3, 2013, Pages 508-517

  Dangelmaier, Carol ^a   Manne, Bhanu Kanth ^a   Liverani, Elizabetta ^a   Jin, Jianguo ^a   Bray, Paul ^b   Kunapuli, Satya P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

Kinases; Platelet pharmacology; Signal transduction

Indexed keywords

PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 4;

ARTICLE; BLOOD CLOT RETRACTION; ENZYME ACTIVITY; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; WESTERN BLOTTING;

KINASES; PLATELET PHARMACOLOGY; SIGNAL TRANSDUCTION;

3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASES; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; BLOOD PLATELETS; CELLS, CULTURED; CLOT RETRACTION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; PLATELET ACTIVATION; PYRIMIDINES; RECEPTORS, THROMBIN; SERINE; SIGNAL TRANSDUCTION; THIOPHENES; THREONINE; THROMBOXANES;

EID: 84897098179     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-06-0484     Document Type: Article

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