Role of phosphoinositide 3-kinase β in glycoprotein VI-mediated Akt activation in platelets

Journal of Biological Chemistry

Volumn 284, Issue 49, 2009, Pages 33763-33772

  Kim, Soochong ^a   Mangin, Pierre ^b   Dangelmaier, Carol ^a   Lillian, Rivka ^b   Jackson, Shaun P ^b   Daniel, James L ^a   Kunapuli, Satya P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; GLYCOPROTEINS; INDIUM PLATING; MAMMALS; PHOSPHORYLATION; PLATELETS;

AKT PHOSPHORYLATION; COLLAGEN RECEPTORS; PHOSPHOINOSITIDE 3-KINASE; PLATELET ACTIVATION; PLATELET AGGREGATION; PROTEIN KINASE C INHIBITORS; RECEPTOR ACTIVATION; RECEPTOR ANTAGONISTS;

CHEMICAL ACTIVATION;

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 5 [5 (4 FLUORO 2 HYDROXYPHENYL)FURFURYLIDENE] 2,4 THIAZOLIDINEDIONE; ADENOSINE DIPHOSPHATE; CLOPIDOGREL; GLYCOPROTEIN VI; INTEGRIN; INTEGRIN ALPHA2B BETA3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE BETA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PURINERGIC P2Y12 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; WILD TYPE;

MUS;

EID: 71749111351     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.048553     Document Type: Article

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