The platelet release reaction: Granules' constituents, secretion and functions

Platelets

Volumn 12, Issue 5, 2001, Pages 261-273

  Rendu, F ^a   Brohard Bohn, B ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GRANULE; CELL ORGANELLE; CHEDIAK HIGASHI SYNDROME; FLOW CYTOMETRY; GRAY SYNDROME; HUMAN; HUMAN CELL; LYSOSOME; MITOCHONDRION; OCULAR ALBINISM; PRIORITY JOURNAL; REVIEW; THROMBOCYTE ACTIVATION; THROMBOCYTE DISORDER; THROMBOCYTE FUNCTION; V QUEBEC SYNDROME;

ANIMALS; BLOOD PLATELETS; CYTOPLASMIC GRANULES; HUMANS; INTRACELLULAR MEMBRANES; TRANSPORT VESICLES;

EID: 0034902812     PISSN: 09537104     EISSN: None     Source Type: Journal    
DOI: 10.1080/09537100120068170     Document Type: Review

References (94)

1. Metabolic energy is required in human platelets at any stage during optical aggregation and secretion
2. The platelet dense tubular system: Its relationship to prostaglandin synthesis and calcium flux
3. Cytochemical localization of K(+)-dependent p-nitrophenyl phosphatase and adenylate cyclase by using one-step method in human washed platelets
4. 2+ transport ATPase system
5. Alpha(2A)-adrenergic receptor stimulation potentiates calcium release in platelets by modulating cAMP levels
6. Defective platelet aggregation to the calcium ionophore A23187 in a patient with a lifelong bleeding disorder
7. Differences in platelet calcium regulation between African americans and caucasians: Implication for the predisposition of African americans to essential hypertension
8. Use of electron microscope for diagnosis of platelet disorders
9. Uranaffin reaction: A new cytochemical technique for the localization of adenine nucleotides in organelles storing biogenic amines
10. Megakaryocyte dense granule components are sorted in multivesicular bodies
11. New aspects on the storage of 5-hydroxytryptamine in blood platelets
12. The localization of calcium and phosphorus in human platelets
13. An improved method for the isolation of dense storage granules from human platelets
14. Initial characterization of human platelet mepacrine-labelled granules isolated using a short metrizamide gradient
15. The human platelet dense granule: Serotonin uptake, tetrabenazine binding, phospholipid and ganglisode profiles
16. Storage of exogenous monoamines and reserpine in 5-hydroxytryptamine organelles of blood platelets
17. The hydrogen ion-pumping adenosine triphosphatetase of platelet dense granule membrane. Differences from F1F0- and phosphoenzyme-type ATPases
18. Mepacrine, a tool for investigating the 5-hydroxytryptamine organelles of blood platelets by fluorescence microscopy
19. Mepacrine stains the dense bodies of human platelets and not platelet lysosomes
20. Association of Ra11A and Ra11B GTP-binding proteins and determination of their concentration and distribution in human platelets
21. Rab geranylgeranyl transferase a mutation in the gunmetal mouse reduces rab prenylation and platelet synthesis
22. Identification of a platelet dense granule membrane protein that is deficient in a patient with the Hermansky-Pudlak syndrome
23. High pp60c-src level in human platelet dense bodies
24. Redistribution of granulophysin and SRC protein in normal and Gray platelets after activation
25. Platelet dense granule membranes contain both granulophysin and P-selectin (GMP-140)
26. The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin
27. The lysosomal granule membrane protein, LAMP-2, is also present in dense granule membrane
28. Platelet and megacaryocyte dense granule contain glycoproteins Ib and IIb-IIIa
29. Platelet α-granules
30. The origin and physiological relevance of alpha-granule adhesive proteins
31. Localization of adhesive proteins in two newly subdivided zones in electron-lucent matrix of human platelet α-granules
32. Factor V is complexed with multimerin in resting platelet lysates and colocalizes with multimerin within alpha-granules
33. Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules
34. Biochemistry and physiology of secreted platelet proteins
35. PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophiles and monocytes
36. Cloning of GMP140, a granule membrane protein of platelets and endothelium; sequence similarity to proteins involved in cell adhesion and inflammation
37. Co-localization of CD9 and GPIIb-IIIa (alpha IIb beta 3 integrin) on activated platelet pseudopods and alpha-granule membranes
38. Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes
39. Thrombin stimulates glucose transport in human platelets via the translocation of the glucose transporter GLUT-3 from alpha-granules to the cell surface
40. Ultrastructural analysis of the distribution of the vitronectin receptor (alpha v beta 3) in human platelets and megakaryocytes reveals an intracellular pool and labelling of the alpha-granule membrane
41. Identification of a 33-Kd protein associated with the alpha-granule membrane (GMP-33) that is expressed on the surface of activated platelets
42. Identification of small GTP-binding rab proteins in human platelets: Thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins
43. Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes
44. 2+-induced α-granule secretion in platelets
45. Identification of primary lysosomes in human megacaryocytes and platelets
46. Human platelet collagenase
47. A unique elastase in human blood platelets
48. Lysosomal membrane glycoproteins in platelets
49. Rapid ultrastructural changes in the dense tubular system following platelet activation
50. Regulated secretion in platelets: Identification of elements of the platelet exocytosis machinery
51. A critical role for N-ethylmaleimide-sensitive fusion protein (NSF) in platelet granule secretion
52. Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 in dense core granule release
53. Molecular mechanisms of platelet exocytosis: Role of SNAP-23 and syntaxin 2 and 4 in lysosome release
54. Proteins of the exocytotic core complex mediate platelet α-granule secretion
55. Serotonin organelles of rabbit platelets contain synaptophysin
56. Identification of a cellubrevin/vesicle associated membrane Protein 3 homologue in human platelets
57. Human platelets contain SNARE proteins and a Seclp homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: Implication for platelet secretion
58. Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets
59. A role for protein kinase C in the membrane fusion necessary for platelet granule secretion
60. ATP is required in platelet serotonin exocytosis for protein phosphorylation and priming of secretory vesicles docked on the plasma membrane
61. Triphosphoinositide breakdown and dense body release as the earliest events in thrombin-induced activation of human platelets
62. Signal transduction in normal and pathological thrombin-stimulated human platelets
63. A flow cytometric assay using mepacine for study of uptake and release of platelet dense granule contents
64. Rapid detection of hereditary and acquired platelet storage pool deficiency by flow cytometry
65. The empty sack syndrome: A platelet storage pool deficiency associated with empty granules
66. On serotonin and migraine: A clinical and pharmacological review
67. Surface expression and functional characterization of alpha-granule factor V in human platelets: Effects of ionophore A23187, thrombin, collagen, and convulxin
68. Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: A potential angiogenesis regulatory factor
69. Osteonectin is an alpha-granule component involved with thrombospondin in platelet aggregation
70. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets
71. Platelet induce human umbilical vein endothelial cell proliferation through P-selectin
72. Platelet-derived collagenase inhibitor: Characterization and subcellular localization
73. Widespread expression of chondroitin sulfate-type serglycins with CD44 binding ability in hematopoietic cells
74. Internalization and recycling of activated receptors
75. Platelets release their lysosomal content in vivo in humans upon activation
76. Lysosome-related organelles
77. Platelet dense granules: Structure, function and implications for haemostasis
78. Studies on a new variant of the Hermansky-Pudlak syndrome: Qualitative ultrastructural and functional abnormalities of the platelet dense bodies associated with a phospholipase A defect
79. Heterogeneous abnormalities of platelet dense granule ultrastructure in 20 patients with congenital storage pool deficiency
80. Increased plasma serotonin in primary hypertension
81. Primary pulmonary hypertension in a patient with a familial platelet storage pool disease: Role of serotonin
82. Albinism associated with hemorrhagic diathesis and unusual pigmented reticular cells in the bone marrow: Report of two cases with histochemical studies
83. Chediak-Higashi syndrome: Observation on the nature of the associated malignancy
84. Evidence that abnormal platelet functions in human Chediak-Higashi syndrome are the resul of a lack of dense bodies
85. Molecular genetics of the Hermansky-Pudlak and Chediak-Higashi syndromes
86. Hermansky-Pudlak syndrome and pale ear: Melanosome-making for the millenium
87. Positional cloning of a gene for Hermansky-Pudlak syndrome, a disorder of cytoplasmic organelles
88. Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak syndrome
89. Gray platelet syndrome. A variety of qualitative platelet disorders
90. Biochemical studies of two patients with the gray platelet syndrome. Selective deficiency of platelet alpha granules
91. Further investigations on Bernard-Soulier platelet abnormalities: A study of 5-HT uptake and mepacrine fluorescence
92. Gray platelet syndrome: α-granule deficiency. Its influence on platelet function
93. Gray platelet syndrome: Demonstration of alpha granule membranes that can fuse with the cell surface
94. Studies of a second family with the Quebec platelet disorder: Evidence that the degradation of the alpha-granule membrane and its soluble contents are not secondary to a defect in targeting proteins to alpha-granules