ADP-stimulated activation of akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 9, 2012, Pages 2232-2240

  O'Brien, Kelly A ^a   Gartner, T Kent ^c   Hay, Nissim ^b   Du, Xiaoping ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF MEMPHIS   (United States)

Author keywords

ADP; Akt; integrin; outside in signaling; platelet

Indexed keywords

ADENOSINE DIPHOSPHATE; FIBRINOGEN; GLYCOGEN SYNTHASE KINASE 3BETA; INTEGRIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y12 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SPREADING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MOUSE; NONHUMAN; OUTSIDE IN SIGNALING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; THROMBOCYTE;

ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD PLATELETS; CELL SHAPE; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INTEGRINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PLATELET ACTIVATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y1; RECEPTORS, PURINERGIC P2Y12; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TIME FACTORS;

EID: 84865447255     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.254680     Document Type: Article

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