-
1
-
-
0034383949
-
The regulation of protein function by multisite phosphorylation - A 25 year update
-
Cohen P. The regulation of protein function by multisite phosphorylation - a 25 year update. Trends Biochem. Sci. 25:2000;596-601.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 596-601
-
-
Cohen, P.1
-
2
-
-
0034614490
-
Signaling - 2000 and beyond
-
Hunter T. Signaling - 2000 and beyond. Cell. 100:2000;113-127.
-
(2000)
Cell
, vol.100
, pp. 113-127
-
-
Hunter, T.1
-
3
-
-
0032988329
-
Protein phosphorylation and signal transduction
-
Graves J.D., Krebs E.G. Protein phosphorylation and signal transduction. Pharmacol. Ther. 82:1999;111-121.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 111-121
-
-
Graves, J.D.1
Krebs, E.G.2
-
4
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Stokoe D., et al. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science. 277:1997;567-570.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
-
5
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
-
Alessi D.R., et al. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr. Biol. 7:1997;261-269.
-
(1997)
Curr. Biol.
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
-
6
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G., et al. The protein kinase complement of the human genome. Science. 298:2002;1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
-
7
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
Pullen N., et al. Phosphorylation and activation of p70s6k by PDK1. Science. 279:1998;707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
-
8
-
-
0033578776
-
90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1
-
Jensen C.J., et al. 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. J. Biol. Chem. 274:1999;27168-27176.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 27168-27176
-
-
Jensen, C.J.1
-
9
-
-
0033615078
-
Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK
-
Richards S.A., et al. Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK. Curr. Biol. 9:1999;810-820.
-
(1999)
Curr. Biol.
, vol.9
, pp. 810-820
-
-
Richards, S.A.1
-
10
-
-
0032566691
-
Protein kinase C isotypes controlled by phosphoinositide3-kinase through the protein kinase PDK1
-
Le Good J.A., et al. Protein kinase C isotypes controlled by phosphoinositide3-kinase through the protein kinase PDK1. Science. 281:1998;2042-2045.
-
(1998)
Science
, vol.281
, pp. 2042-2045
-
-
Le Good, J.A.1
-
11
-
-
0032563936
-
Regulation of protein kinase Cζ by PI 3-kinase and PDK-1
-
Chou M.M., et al. Regulation of protein kinase Cζ by PI 3-kinase and PDK-1. Curr. Biol. 8:1998;1069-1077.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1069-1077
-
-
Chou, M.M.1
-
12
-
-
0033151832
-
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
-
Park J., et al. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J. 18:1999;3024-3033.
-
(1999)
EMBO J.
, vol.18
, pp. 3024-3033
-
-
Park, J.1
-
13
-
-
0033560707
-
Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2
-
Kobayashi T., Cohen P. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem. J. 339:1999;319-328.
-
(1999)
Biochem. J.
, vol.339
, pp. 319-328
-
-
Kobayashi, T.1
Cohen, P.2
-
14
-
-
1542294711
-
Peroxisomal targeting as a tool for assaying protein-protein interactions in the living cell: CISK binds PDK-1 in vivo in a phosphorylation-dependent manner
-
(in press).
-
Nilsen, T. et al. Peroxisomal targeting as a tool for assaying protein-protein interactions in the living cell: CISK binds PDK-1 in vivo in a phosphorylation-dependent manner. J. Biol. Chem. (in press).
-
J. Biol. Chem.
-
-
Nilsen, T.1
-
15
-
-
0034624990
-
Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton
-
Dong L.Q., et al. Phosphorylation of protein kinase N by phosphoinositide-dependent protein kinase-1 mediates insulin signals to the actin cytoskeleton. Proc. Natl. Acad. Sci. U. S. A. 97:2000;5089-5094.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 5089-5094
-
-
Dong, L.Q.1
-
16
-
-
0032585532
-
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
-
Dutil E.M., et al. Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1). Curr. Biol. 8:1998;1366-1375.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1366-1375
-
-
Dutil, E.M.1
-
17
-
-
0032544011
-
Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
-
Cheng X., et al. Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc. Natl. Acad. Sci. U. S. A. 95:1998;9849-9854.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 9849-9854
-
-
Cheng, X.1
-
18
-
-
0041355220
-
Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide-dependent kinase 1
-
Torbett N.E., et al. Hyperosmotic-induced protein kinase N 1 activation in a vesicular compartment is dependent upon Rac1 and 3-phosphoinositide- dependent kinase 1. J. Biol. Chem. 278:2003;32344-32351.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 32344-32351
-
-
Torbett, N.E.1
-
19
-
-
0033545393
-
Intracellular signalling: PDK1 - A kinase at the hub of things
-
Belham C., et al. Intracellular signalling: PDK1 - a kinase at the hub of things. Curr. Biol. 9:1999;R93-R96.
-
(1999)
Curr. Biol.
, vol.9
, pp. 93-R96
-
-
Belham, C.1
-
20
-
-
0034653608
-
The PI3K-PDK1 connection: More than just a road to PKB
-
Vanhaesebroeck B., Alessi D.R. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346:2000;561-576.
-
(2000)
Biochem. J.
, vol.346
, pp. 561-576
-
-
Vanhaesebroeck, B.1
Alessi, D.R.2
-
21
-
-
0035213641
-
AGC protein kinase phosphorylation and protein kinase C
-
Parker P.J., Parkinson S.J. AGC protein kinase phosphorylation and protein kinase C. Biochem. Soc. Trans. 29:2001;860-863.
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 860-863
-
-
Parker, P.J.1
Parkinson, S.J.2
-
23
-
-
0037034928
-
Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine)
-
Sato S., et al. Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine). Oncogene. 21:2002;1727-1738.
-
(2002)
Oncogene
, vol.21
, pp. 1727-1738
-
-
Sato, S.1
-
24
-
-
0036909402
-
Regulation of protein kinases in insulin, growth factor and Wnt signalling
-
Pearl L.H., Barford D. Regulation of protein kinases in insulin, growth factor and Wnt signalling. Curr. Opin. Struct. Biol. 12:2002;761-767.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 761-767
-
-
Pearl, L.H.1
Barford, D.2
-
25
-
-
0034644523
-
Cellular signaling: Pivoting around PDK-1
-
Toker A., Newton A.C. Cellular signaling: pivoting around PDK-1. Cell. 103:2000;185-188.
-
(2000)
Cell
, vol.103
, pp. 185-188
-
-
Toker, A.1
Newton, A.C.2
-
26
-
-
0037337159
-
Regulation of the ABC kinases by phosphorylation: Protein kinase C as a paradigm
-
Newton A.C. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem. J. 370:2003;361-371.
-
(2003)
Biochem. J.
, vol.370
, pp. 361-371
-
-
Newton, A.C.1
-
27
-
-
0037954572
-
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions
-
Biondi R.M., Nebreda A.R. Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions. Biochem. J. 372:2003;1-13.
-
(2003)
Biochem. J.
, vol.372
, pp. 1-13
-
-
Biondi, R.M.1
Nebreda, A.R.2
-
28
-
-
0035797892
-
Insulin stimulates increased catalytic activity of phosphoinositide- dependent kinase-1 by a phosphorylation-dependent mechanism
-
Chen H., et al. Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism. Biochemistry. 40:2001;11851-11859.
-
(2001)
Biochemistry
, vol.40
, pp. 11851-11859
-
-
Chen, H.1
-
29
-
-
0033769436
-
Peroxovanadate induces tyrosine phosphorylation of phosphoinositide- dependent protein kinase-1 potential involvement of src kinase
-
Grillo S., et al. Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1 potential involvement of src kinase. Eur. J. Biochem. 267:2000;6642-6649.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 6642-6649
-
-
Grillo, S.1
-
30
-
-
0034643868
-
Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1)
-
Prasad N., et al. Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1). Biochemistry. 39:2000;6929-6935.
-
(2000)
Biochemistry
, vol.39
, pp. 6929-6935
-
-
Prasad, N.1
-
31
-
-
0035813230
-
Identification of tyrosine phosphorylation sites on 3-phosphoinositide- dependent protein kinase-1 and their role in regulating kinase activity
-
Park J., et al. Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity. J. Biol. Chem. 276:2001;37459-37471.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37459-37471
-
-
Park, J.1
-
32
-
-
12444299997
-
RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): An alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1
-
Kim D.W., et al. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide- dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1. Mol. Endocrinol. 17:2003;1382-1394.
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1382-1394
-
-
Kim, D.W.1
-
33
-
-
0026342401
-
Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
-
Knighton D.R., et al. Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. Science. 253:1991;407-414.
-
(1991)
Science
, vol.253
, pp. 407-414
-
-
Knighton, D.R.1
-
34
-
-
0035413608
-
Dynamics of cAMP-dependent protein kinase
-
Johnson D.A., et al. Dynamics of cAMP-dependent protein kinase. Chem. Rev. 101:2001;2243-2270.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2243-2270
-
-
Johnson, D.A.1
-
35
-
-
0034613270
-
Threonine phosphorylation of the β3 integrin cytoplasmic tail, at a site recognized by PDK1 and Akt/PKB in vitro, regulates Shc binding
-
Kirk R.I., et al. Threonine phosphorylation of the β3 integrin cytoplasmic tail, at a site recognized by PDK1 and Akt/PKB in vitro, regulates Shc binding. J. Biol. Chem. 275:2000;30901-30906.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30901-30906
-
-
Kirk, R.I.1
-
36
-
-
0034731505
-
P21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1)
-
King C.C., et al. p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1). J. Biol. Chem. 275:2000;41201-41209.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41201-41209
-
-
King, C.C.1
-
37
-
-
0242580122
-
Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions
-
Taniyama Y., et al. Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions. Mol. Cell. Biol. 23:2003;8019-8029.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8019-8029
-
-
Taniyama, Y.1
-
38
-
-
0033601217
-
Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252
-
Balendran A., et al. Evidence that 3-phosphoinositide-dependent protein kinase-1 mediates phosphorylation of p70 S6 kinase in vivo at Thr-412 as well as Thr-252. J. Biol. Chem. 274:1999;37400-37406.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37400-37406
-
-
Balendran, A.1
-
39
-
-
0242612949
-
A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1
-
Frodin M., et al. A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1. EMBO J. 19:2000;2924-2934.
-
(2000)
EMBO J.
, vol.19
, pp. 2924-2934
-
-
Frodin, M.1
-
40
-
-
0035882103
-
The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB
-
Biondi R.M., et al. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB. EMBO J. 20:2001;4380-4390.
-
(2001)
EMBO J.
, vol.20
, pp. 4380-4390
-
-
Biondi, R.M.1
-
41
-
-
0037107414
-
A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation
-
Frodin M., et al. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. EMBO J. 21:2002;5396-5407.
-
(2002)
EMBO J.
, vol.21
, pp. 5396-5407
-
-
Frodin, M.1
-
42
-
-
0030740005
-
The modular phosphorylation and activation of p70s6k
-
Pullen N., Thomas G. The modular phosphorylation and activation of p70s6k. FEBS Lett. 410:1997;78-82.
-
(1997)
FEBS Lett.
, vol.410
, pp. 78-82
-
-
Pullen, N.1
Thomas, G.2
-
43
-
-
0032518467
-
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi D.R., et al. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol. 8:1998;69-81.
-
(1998)
Curr. Biol.
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
-
44
-
-
0034646677
-
Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase
-
Flynn P., et al. Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase. J. Biol. Chem. 275:2000;11064-11070.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11064-11070
-
-
Flynn, P.1
-
45
-
-
0036333737
-
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
-
Scheid M.P., et al. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell. Biol. 22:2002;6247-6260.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6247-6260
-
-
Scheid, M.P.1
-
46
-
-
0035413601
-
Protein kinase C: Structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
-
Newton A.C. Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem. Rev. 101:2001;2353-2364.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2353-2364
-
-
Newton, A.C.1
-
47
-
-
0034651539
-
Multiple pathways control protein kinase C phosphorylation
-
Parekh D.B., et al. Multiple pathways control protein kinase C phosphorylation. EMBO J. 19:2000;496-503.
-
(2000)
EMBO J.
, vol.19
, pp. 496-503
-
-
Parekh, D.B.1
-
48
-
-
0035380478
-
The carboxyl terminus of protein kinase C provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1
-
Gao T., et al. The carboxyl terminus of protein kinase C provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1. J. Biol. Chem. 276:2001;19588-19596.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19588-19596
-
-
Gao, T.1
-
49
-
-
0030250879
-
Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα
-
Bornancin F., Parker P.J. Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Cα Curr. Biol. 6:1996;1114-1123.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1114-1123
-
-
Bornancin, F.1
Parker, P.J.2
-
50
-
-
0034176579
-
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
-
Williams M.R., et al. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr. Biol. 10:2000;439-448.
-
(2000)
Curr. Biol.
, vol.10
, pp. 439-448
-
-
Williams, M.R.1
-
51
-
-
0034634443
-
Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms
-
Balendran A., et al. Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. FEBS Lett. 484:2000;217-223.
-
(2000)
FEBS Lett.
, vol.484
, pp. 217-223
-
-
Balendran, A.1
-
52
-
-
0034161251
-
Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA
-
Biondi R.M., et al. Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA. EMBO J. 19:2000;979-988.
-
(2000)
EMBO J.
, vol.19
, pp. 979-988
-
-
Biondi, R.M.1
-
53
-
-
0037102153
-
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
-
Biondi R.M., et al. High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site. EMBO J. 21:2002;4219-4228.
-
(2002)
EMBO J.
, vol.21
, pp. 4219-4228
-
-
Biondi, R.M.1
-
54
-
-
0036295728
-
Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
-
Yang J., et al. Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation. Mol. Cell. 9:2002;1227-1240.
-
(2002)
Mol. Cell
, vol.9
, pp. 1227-1240
-
-
Yang, J.1
-
55
-
-
0037229885
-
Crystal structure of an inactive akt2 kinase domain
-
Huang X., et al. Crystal structure of an inactive akt2 kinase domain. Structure (Camb). 11:2003;21-30.
-
(2003)
Structure (Camb)
, vol.11
, pp. 21-30
-
-
Huang, X.1
-
56
-
-
18744373865
-
Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP
-
Yang J., et al. Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP. Nat. Struct. Biol. 9:2002;940-944.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 940-944
-
-
Yang, J.1
-
57
-
-
0037155901
-
Involvement of Hsp90 in signaling and stability of 3-phosphoinositide- dependent kinase-1
-
Fujita N., et al. Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1. J. Biol. Chem. 277:2002;10346-10353.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10346-10353
-
-
Fujita, N.1
-
58
-
-
0037200043
-
The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C
-
Gao T., Newton A.C. The turn motif is a phosphorylation switch that regulates the binding of Hsp70 to protein kinase C. J. Biol. Chem. 277:2002;31585-31592.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31585-31592
-
-
Gao, T.1
Newton, A.C.2
-
59
-
-
0036849331
-
PKB binding proteins. Getting in on the Akt
-
Brazil D.P., et al. PKB binding proteins. Getting in on the Akt. Cell. 111:2002;293-303.
-
(2002)
Cell
, vol.111
, pp. 293-303
-
-
Brazil, D.P.1
-
60
-
-
0034718540
-
Modulation of Akt kinase activity by binding to Hsp90
-
Sato S., et al. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. U. S. A. 97:2000;10832-10837.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 10832-10837
-
-
Sato, S.1
-
61
-
-
0043234527
-
Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: Calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex
-
Takahashi S., Mendelsohn M.E. Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex. J. Biol. Chem. 278:2003;30821-30827.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 30821-30827
-
-
Takahashi, S.1
Mendelsohn, M.E.2
-
62
-
-
0037131187
-
Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function
-
Basso A.D., et al. Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function. J. Biol. Chem. 277:2002;39858-39866.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39858-39866
-
-
Basso, A.D.1
-
63
-
-
0037013152
-
Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release
-
Fontana J., et al. Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ. Res. 90:2002;866-873.
-
(2002)
Circ. Res.
, vol.90
, pp. 866-873
-
-
Fontana, J.1
-
64
-
-
0041344614
-
Heat shock protein 27 controls apoptosis by regulating Akt activation
-
Rane M.J., et al. Heat shock protein 27 controls apoptosis by regulating Akt activation. J. Biol. Chem. 278:2003;27828-27835.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27828-27835
-
-
Rane, M.J.1
-
65
-
-
0034617281
-
A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Cζ (PKCζ) and PKC-related kinase 2 by PDK1
-
Balendran A., et al. A 3-phosphoinositide-dependent protein kinase-1 (PDK1) docking site is required for the phosphorylation of protein kinase Cζ (PKCζ) and PKC-related kinase 2 by PDK1. J. Biol. Chem. 275:2000;20806-20813.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20806-20813
-
-
Balendran, A.1
-
66
-
-
0035413599
-
Phosphoinositide-regulated kinases and phosphoinositide phosphatases
-
Leslie N.R., et al. Phosphoinositide-regulated kinases and phosphoinositide phosphatases. Chem. Rev. 101:2001;2365-2380.
-
(2001)
Chem. Rev.
, vol.101
, pp. 2365-2380
-
-
Leslie, N.R.1
-
67
-
-
0042967831
-
In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation
-
Collins B.J., et al. In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation. EMBO J. 22:2003;4202-4211.
-
(2003)
EMBO J.
, vol.22
, pp. 4202-4211
-
-
Collins, B.J.1
-
68
-
-
0035424237
-
ER quality control: Towards an understanding at the molecular level
-
Ellgaard L., Helenius A. ER quality control: towards an understanding at the molecular level. Curr. Opin. Cell Biol. 13:2001;431-437.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 431-437
-
-
Ellgaard, L.1
Helenius, A.2
-
70
-
-
0033782777
-
Protein glucosylation and its role in protein folding
-
Parodi A.J. Protein glucosylation and its role in protein folding. Annu. Rev. Biochem. 69:2000;69-93.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 69-93
-
-
Parodi, A.J.1
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