Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2)

Journal of Biological Chemistry

Volumn 288, Issue 11, 2013, Pages 7717-7726

  Manne, Bhanu Kanth ^a   Getz, Todd M ^a   Hughes, Craig E ^b   Alshehri, Osama ^b   Dangelmaier, Carol ^a   Naik, Ulhas P ^c   Watson, Steve P ^b   Kunapuli, Satya P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION-DEPENDENT MANNERS; FUCUS VESICULOSUS; MURINE PLATELETS; PLATELET ACTIVATION; PLATELET AGONISTS; SIGNALING PATHWAYS; SULFATED POLYSACCHARIDES; TISSUE FACTOR PATHWAY INHIBITORS;

TISSUE;

PLATELETS;

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FC RECEPTOR; FUCOIDIN; PROTEIN KINASE SYK;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ANIMALS; ANTICOAGULANTS; BLOOD PLATELETS; FLOW CYTOMETRY; HEMOPHILIA A; HUMANS; IMMUNOPRECIPITATION; LECTINS, C-TYPE; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PLATELET ACTIVATION; POLYSACCHARIDES; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84875147323     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.424473     Document Type: Article

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