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Volumn 6, Issue 4, 2014, Pages 1177-1192

Analysis of individual and combined effects of ochratoxin a and zearalenone on HepG2 and KK-1 cells with mathematical models

Author keywords

Combined effect; Concentration addition; Independent addition; Ochratoxin A; Risk assessment; Zearalenone

Indexed keywords

OCHRATOXIN; REACTIVE OXYGEN METABOLITE; ZEARALENONE;

EID: 84897090898     PISSN: 20726651     EISSN: None     Source Type: Journal    
DOI: 10.3390/toxins6041177     Document Type: Article
Times cited : (45)

References (52)
  • 3
    • 35948944283 scopus 로고    scopus 로고
    • Some major mycotoxins and their mycotoxicoses-An overview
    • Richard, J.L. Some major mycotoxins and their mycotoxicoses-An overview. Int. J. Food Microbiol. 2007, 119, 3-10.
    • (2007) Int. J. Food Microbiol , vol.119 , pp. 3-10
    • Richard, J.L.1
  • 5
    • 4444242105 scopus 로고    scopus 로고
    • Combined toxic effects of mycotoxins
    • Speijers, G.J.; Speijers, M.H. Combined toxic effects of mycotoxins. Toxicol. Lett. 2004, 153, 91-98.
    • (2004) Toxicol. Lett , vol.153 , pp. 91-98
    • Speijers, G.J.1    Speijers, M.H.2
  • 6
    • 79952089126 scopus 로고    scopus 로고
    • Ochratoxins-food contaminants: Impact on human health
    • Reddy, L.; Bhoola, K. Ochratoxins-food contaminants: Impact on human health. Toxins 2010, 2, 771-779.
    • (2010) Toxins , vol.2 , pp. 771-779
    • Reddy, L.1    Bhoola, K.2
  • 9
    • 80052834802 scopus 로고    scopus 로고
    • Ochratoxin Areduces aflatoxin B1 induced DNA damage detected by the comet assay in Hep G2 cells
    • Corcuera, L.A.; Arbillaga, L.; Vettorazzi, A.; Azqueta, A.; Lopez de Cerain, A. Ochratoxin Areduces aflatoxin B1 induced DNA damage detected by the comet assay in Hep G2 cells. Food Chem. Toxicol. 2011, 49, 2883-2889.
    • (2011) Food Chem. Toxicol , vol.49 , pp. 2883-2889
    • Corcuera, L.A.1    Arbillaga, L.2    Vettorazzi, A.3    Azqueta, A.4    de Lopez, C.A.5
  • 10
    • 84875046648 scopus 로고    scopus 로고
    • Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A
    • Zheng, J.; Zhang, Y.; Xu, W.; Luo, Y.; Hao, J.; Shen, X.L.; Yang, X.; Li, X.; Huang, K. Zinc protects HepG2 cells against the oxidative damage and DNA damage induced by ochratoxin A. Toxicol. Appl. Pharmacol. 2013, 268, 123-131.
    • (2013) Toxicol Appl. Pharmacol , vol.268 , pp. 123-131
    • Zheng, J.1    Zhang, Y.2    Xu, W.3    Luo, Y.4    Hao, J.5    Shen, X.L.6    Yang, X.7    Li, X.8    Huang, K.9
  • 11
    • 84872674727 scopus 로고    scopus 로고
    • An iTRAQ-based mitoproteomics approach for profiling the nephrotoxicity mechanisms of ochratoxin A in HEK 293 cells
    • Shen, X.L.; Zhang, Y.; Xu, W.; Liang, R.; Zheng, J.; Luo, Y.; Wang, Y.; Huang, K. An iTRAQ-based mitoproteomics approach for profiling the nephrotoxicity mechanisms of ochratoxin A in HEK 293 cells. J. Proteomics 2013, 78, 398-415.
    • (2013) J. Proteomics , vol.78 , pp. 398-415
    • Shen, X.L.1    Zhang, Y.2    Xu, W.3    Liang, R.4    Zheng, J.5    Luo, Y.6    Wang, Y.7    Huang, K.8
  • 12
    • 84859785087 scopus 로고    scopus 로고
    • An update on direct genotoxicity as a molecular mechanism of ochratoxin A carcinogenicity
    • Pfohl-Leszkowicz, A.; Manderville, R.A. An update on direct genotoxicity as a molecular mechanism of ochratoxin A carcinogenicity. Chem. Res. Toxicol. 2012, 25, 252-262.
    • (2012) Chem. Res. Toxicol , vol.25 , pp. 252-262
    • Pfohl-Leszkowicz, A.1    Manderville, R.A.2
  • 13
  • 14
    • 79957856788 scopus 로고    scopus 로고
    • Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines
    • Ali, R.; Mittelstaedt, R.A.; Shaddock, J.G.; Ding, W.; Bhalli, J.A.; Khan, Q.M.; Heflich, R.H. Comparative analysis of micronuclei and DNA damage induced by Ochratoxin A in two mammalian cell lines. Mutat. Res. 2011, 723, 58-64.
    • (2011) Mutat. Res , vol.723 , pp. 58-64
    • Ali, R.1    Mittelstaedt, R.A.2    Shaddock, J.G.3    Ding, W.4    Bhalli, J.A.5    Khan, Q.M.6    Heflich, R.H.7
  • 15
    • 0034982739 scopus 로고    scopus 로고
    • Structure-activity relationships for human estrogenic activity in zearalenone mycotoxins
    • Shier, W.T.; Shier, A.C.; Xie, W.; Mirocha, C.J. Structure-activity relationships for human estrogenic activity in zearalenone mycotoxins. Toxicon 2001, 39, 1435-1438.
    • (2001) Toxicon , vol.39 , pp. 1435-1438
    • Shier, W.T.1    Shier, A.C.2    Xie, W.3    Mirocha, C.J.4
  • 17
    • 72149113305 scopus 로고    scopus 로고
    • Comparative mechanisms of zearalenone and ochratoxin A toxicities on cultured HepG2 cells: Is oxidative stress a common process?
    • El Golli Bennour, E.; Bouaziz, C.; Ladjimi, M.; Renaud, F.; Bacha, H. Comparative mechanisms of zearalenone and ochratoxin A toxicities on cultured HepG2 cells: Is oxidative stress a common process? Environ. Toxicol. 2009, 24, 538-548.
    • (2009) Environ. Toxicol , vol.24 , pp. 538-548
    • El Golli, B.E.1    Bouaziz, C.2    Ladjimi, M.3    Renaud, F.4    Bacha, H.5
  • 18
    • 33947387988 scopus 로고    scopus 로고
    • The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: Oxidative DNA damage, gluthatione depletion and stress proteins induction
    • Hassen, W.; Ayed-Boussema, I.; Oscoz, A.A.; Lopez Ade, C.; Bacha, H. The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: Oxidative DNA damage, gluthatione depletion and stress proteins induction. Toxicology 2007, 232, 294-302.
    • (2007) Toxicology , vol.232 , pp. 294-302
    • Hassen, W.1    Ayed-Boussema, I.2    Oscoz, A.A.3    Lopez, A.C.4    Bacha, H.5
  • 19
    • 79960697121 scopus 로고    scopus 로고
    • Hsp70 expression as biomarkers of oxidative stress: Mycotoxins' exploration
    • El Golli-Bennour, E.; Bacha, H. Hsp70 expression as biomarkers of oxidative stress: Mycotoxins' exploration. Toxicology 2011, 287, 1-7.
    • (2011) Toxicology , vol.287 , pp. 1-7
    • El Golli-Bennour, E.1    Bacha, H.2
  • 21
    • 0028224043 scopus 로고
    • Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes
    • Lu, S.C.; Huang, H.Y. Comparison of sulfur amino acid utilization for GSH synthesis between HepG2 cells and cultured rat hepatocytes. Biochem. Pharmacol. 1994, 47, 859-869.
    • (1994) Biochem. Pharmacol , vol.47 , pp. 859-869
    • Lu, S.C.1    Huang, H.Y.2
  • 22
    • 0032402090 scopus 로고    scopus 로고
    • Human-derived cell lines to study xenobiotic metabolism
    • Urani, C.; Doldi, M.; Crippa, S.; Camatini, M. Human-derived cell lines to study xenobiotic metabolism. Chemosphere 1998, 37, 2785-2795.
    • (1998) Chemosphere , vol.37 , pp. 2785-2795
    • Urani, C.1    Doldi, M.2    Crippa, S.3    Camatini, M.4
  • 23
    • 56049092723 scopus 로고    scopus 로고
    • Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells
    • Bouaziz, C.; Sharaf El Dein, O.; El Golli, E.; Abid-Essefi, S.; Brenner, C.; Lemaire, C.; Bacha, H. Different apoptotic pathways induced by zearalenone, T-2 toxin and ochratoxin A in human hepatoma cells. Toxicology 2008, 254, 19-28.
    • (2008) Toxicology , vol.254 , pp. 19-28
    • Bouaziz, C.1    El Sharaf, D.O.2    El Golli, E.3    Abid-Essefi, S.4    Brenner, C.5    Lemaire, C.6    Bacha, H.7
  • 24
    • 12844251475 scopus 로고    scopus 로고
    • The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: An overview
    • Calabrese, E.J.; Blain, R. The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: An overview. Toxicol. Appl. Pharmacol. 2005, 202, 289-301.
    • (2005) Toxicol. Appl. Pharmacol , vol.202 , pp. 289-301
    • Calabrese, E.J.1    Blain, R.2
  • 25
    • 84862908121 scopus 로고    scopus 로고
    • Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3-and caspase-9-dependent mitochondrial signaling pathway
    • Zhu, L.; Yuan, H.; Guo, C.; Lu, Y.; Deng, S.; Yang, Y.; Wei, Q.; Wen, L.; He, Z. Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3-and caspase-9-dependent mitochondrial signaling pathway. J. Cell Physiol. 2012, 227, 1814-1820.
    • (2012) J. Cell Physiol , vol.227 , pp. 1814-1820
    • Zhu, L.1    Yuan, H.2    Guo, C.3    Lu, Y.4    Deng, S.5    Yang, Y.6    Wei, Q.7    Wen, L.8    He, Z.9
  • 26
    • 33845738791 scopus 로고    scopus 로고
    • Influence of mycotoxin zearalenone and its derivatives (alpha and beta zearalenol) on apoptosis and proliferation of cultured granulosa cells from equine ovaries
    • Minervini, F.; Giannoccaro, A.; Fornelli, F.; Dell'Aquila, M.E.; Minoia, P.; Visconti, A. Influence of mycotoxin zearalenone and its derivatives (alpha and beta zearalenol) on apoptosis and proliferation of cultured granulosa cells from equine ovaries. Reprod. Biol. Endocrinol. 2006, 4, 62.
    • (2006) Reprod. Biol. Endocrinol , vol.4 , pp. 62
    • Minervini, F.1    Giannoccaro, A.2    Fornelli, F.3    Dell'Aquila, M.E.4    Minoia, P.5    Visconti, A.6
  • 27
    • 30744469267 scopus 로고    scopus 로고
    • Cancer biology and hormesis: Human tumor cell lines commonly display hormetic (biphasic) dose responses
    • Calabrese, E.J. Cancer biology and hormesis: Human tumor cell lines commonly display hormetic (biphasic) dose responses. Crit. Rev. Toxicol. 2005, 35, 463-582.
    • (2005) Crit. Rev. Toxicol , vol.35 , pp. 463-582
    • Calabrese, E.J.1
  • 28
    • 69949103469 scopus 로고    scopus 로고
    • A perspective on the scientific, philosophical, and policy dimensions of hormesis
    • Hoffmann, G.R. A perspective on the scientific, philosophical, and policy dimensions of hormesis. Dose Response 2009, 7, 1-51.
    • (2009) Dose Response , vol.7 , pp. 1-51
    • Hoffmann, G.R.1
  • 29
    • 84897121678 scopus 로고    scopus 로고
    • Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells
    • Mary, V.S.; Theumer, M.G.; Arias, S.L.; Rubinstein, H.R. Reactive oxygen species sources and biomolecular oxidative damage induced by aflatoxin B1 and fumonisin B1 in rat spleen mononuclear cells. Toxicology 2012, 302, 299-307.
    • (2012) Toxicology , vol.302 , pp. 299-307
    • Mary, V.S.1    Theumer, M.G.2    Arias, S.L.3    Rubinstein, H.R.4
  • 30
    • 33644779615 scopus 로고    scopus 로고
    • In vitro investigation of individual and combined cytotoxic effects of ochratoxin A and other selected mycotoxins on renal cells
    • Heussner, A.H.; Dietrich, D.R.; O'Brien, E. In vitro investigation of individual and combined cytotoxic effects of ochratoxin A and other selected mycotoxins on renal cells. Toxicol. In Vitro 2006, 20, 332-341.
    • (2006) Toxicol. In Vitro , vol.20 , pp. 332-341
    • Heussner, A.H.1    Dietrich, D.R.2    O'Brien, E.3
  • 31
    • 84865572978 scopus 로고    scopus 로고
    • Co-exposure of Fusarium mycotoxins: In vitro myelotoxicity assessment on human hematopoietic progenitors
    • Ficheux, A.S.; Sibiril, Y.; Parent-Massin, D. Co-exposure of Fusarium mycotoxins: In vitro myelotoxicity assessment on human hematopoietic progenitors. Toxicon 2012, 60, 1171-1179.
    • (2012) Toxicon , vol.60 , pp. 1171-1179
    • Ficheux, A.S.1    Sibiril, Y.2    Parent-Massin, D.3
  • 32
    • 80051920486 scopus 로고    scopus 로고
    • Cytotoxic effects of mycotoxin combinations in mammalian kidney cells
    • Ruiz, M.J.; Macakova, P.; Juan-Garcia, A.; Font, G. Cytotoxic effects of mycotoxin combinations in mammalian kidney cells. Food Chem. Toxicol. 2011, 49, 2718-2724.
    • (2011) Food Chem. Toxicol , vol.49 , pp. 2718-2724
    • Ruiz, M.J.1    Macakova, P.2    Juan-Garcia, A.3    Font, G.4
  • 33
    • 0029036955 scopus 로고
    • The search for synergy: A critical review from a response surface perspective
    • Greco, W.R.; Bravo, G.; Parsons, J.C. The search for synergy: A critical review from a response surface perspective. Pharmacol. Rev. 1995, 47, 331-385.
    • (1995) Pharmacol. Rev , vol.47 , pp. 331-385
    • Greco, W.R.1    Bravo, G.2    Parsons, J.C.3
  • 34
    • 84857872647 scopus 로고    scopus 로고
    • Predictive environmental risk assessment of chemical mixtures: A conceptual framework
    • Backhaus, T.; Faust, M. Predictive environmental risk assessment of chemical mixtures: A conceptual framework. Environ. Sci. Technol. 2012, 46, 2564-2573.
    • (2012) Environ. Sci. Technol , vol.46 , pp. 2564-2573
    • Backhaus, T.1    Faust, M.2
  • 35
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • Bliss, C.I. The toxicity of poisons applied jointly. Ann. Appl. Biol. 1939, 26, 585-615.
    • (1939) Ann. Appl. Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1
  • 36
    • 0021746739 scopus 로고
    • Inhibition of protein synthesis in mice by ochratoxin A and its prevention by phenylalanine
    • Creppy, E.E.; Roschenthaler, R.; Dirheimer, G. Inhibition of protein synthesis in mice by ochratoxin A and its prevention by phenylalanine. Food Chem. Toxicol. 1984, 22, 883-886.
    • (1984) Food Chem. Toxicol , vol.22 , pp. 883-886
    • Creppy, E.E.1    Roschenthaler, R.2    Dirheimer, G.3
  • 38
    • 0021012424 scopus 로고
    • Comparative study of the effect of ochratoxin A analogues on yeast aminoacyl-tRNA synthetases and on the growth and protein synthesis of hepatoma cells
    • Creppy, E.E.; Kern, D.; Steyn, P.S.; Vleggaar, R.; Roschenthaler, R.; Dirheimer, G. Comparative study of the effect of ochratoxin A analogues on yeast aminoacyl-tRNA synthetases and on the growth and protein synthesis of hepatoma cells. Toxicol. Lett. 1983, 19, 217-224.
    • (1983) Toxicol. Lett , vol.19 , pp. 217-224
    • Creppy, E.E.1    Kern, D.2    Steyn, P.S.3    Vleggaar, R.4    Roschenthaler, R.5    Dirheimer, G.6
  • 39
    • 84874017274 scopus 로고    scopus 로고
    • Endocrine disrupting effects of ochratoxin A at the level of nuclear receptor activation and steroidogenesis
    • Frizzell, C.; Verhaegen, S.; Ropstad, E.; Elliott, C.T.; Connolly, L. Endocrine disrupting effects of ochratoxin A at the level of nuclear receptor activation and steroidogenesis. Toxicol. Lett. 2013, 217, 243-250.
    • (2013) Toxicol. Lett , vol.217 , pp. 243-250
    • Frizzell, C.1    Verhaegen, S.2    Ropstad, E.3    Elliott, C.T.4    Connolly, L.5
  • 40
    • 33751251394 scopus 로고    scopus 로고
    • Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin
    • Zinedine, A.; Soriano, J.M.; Molto, J.C.; Manes, J. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin. Food Chem. Toxicol. 2007, 45, 1-18.
    • (2007) Food Chem. Toxicol , vol.45 , pp. 1-18
    • Zinedine, A.1    Soriano, J.M.2    Molto, J.C.3    Manes, J.4
  • 41
    • 0345791439 scopus 로고    scopus 로고
    • Ochratoxin A and zearalenone: A comparative study on genotoxic effects and cell death induced in bovine lymphocytes
    • Lioi, M.B.; Santoro, A.; Barbieri, R.; Salzano, S.; Ursini, M.V. Ochratoxin A and zearalenone: A comparative study on genotoxic effects and cell death induced in bovine lymphocytes. Mutat. Res. 2004, 557, 19-27.
    • (2004) Mutat. Res , vol.557 , pp. 19-27
    • Lioi, M.B.1    Santoro, A.2    Barbieri, R.3    Salzano, S.4    Ursini, M.V.5
  • 42
    • 75149113718 scopus 로고    scopus 로고
    • Structures of covalent adducts between DNA and ochratoxin A: A new factor in debate about genotoxicity and human risk assessment
    • Mantle, P.G.; Faucet-Marquis, V.; Manderville, R.A.; Squillaci, B.; Pfohl-Leszkowicz, A. Structures of covalent adducts between DNA and ochratoxin A: A new factor in debate about genotoxicity and human risk assessment. Chem. Res. Toxicol. 2010, 23, 89-98.
    • (2010) Chem. Res. Toxicol , vol.23 , pp. 89-98
    • Mantle, P.G.1    Faucet-Marquis, V.2    Manderville, R.A.3    Squillaci, B.4    Pfohl-Leszkowicz, A.5
  • 43
    • 0028839564 scopus 로고
    • Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues
    • Pfohl-Leszkowicz, A.; Chekir-Ghedira, L.; Bacha, H. Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues. Carcinogenesis 1995, 16, 2315-2320.
    • (1995) Carcinogenesis , vol.16 , pp. 2315-2320
    • Pfohl-Leszkowicz, A.1    Chekir-Ghedira, L.2    Bacha, H.3
  • 45
    • 0003067199 scopus 로고    scopus 로고
    • Statistical analysis of interactive cytotoxicity in human epidermal keratinocytes following exposure to a mixture of four metals
    • Gennings, C.; Carter, W.; Campain, J.; Bae, D.-S.; Yang, R.H. Statistical analysis of interactive cytotoxicity in human epidermal keratinocytes following exposure to a mixture of four metals. JABES 2002, 7, 58-73.
    • (2002) JABES , vol.7 , pp. 58-73
    • Gennings, C.1    Carter, W.2    Campain, J.3    Bae, D.-S.4    Yang, R.H.5
  • 46
    • 31244431993 scopus 로고    scopus 로고
    • Toxicity of binary mixtures of cadmium-copper and carbendazim-copper to the nematode Caenorhabditis elegans
    • Jonker, M.J.; Piskiewicz, A.M.; Ivorra i Castella, N.; Kammenga, J.E. Toxicity of binary mixtures of cadmium-copper and carbendazim-copper to the nematode Caenorhabditis elegans. Environ. Toxicol. Chem. 2004, 23, 1529-1537.
    • (2004) Environ. Toxicol. Chem , vol.23 , pp. 1529-1537
    • Jonker, M.J.1    Piskiewicz, A.M.2    Ivorra i Castella, N.3    Kammenga, J.E.4
  • 47
    • 84863277188 scopus 로고    scopus 로고
    • Analysis of combined effects of nonylphenol and Monobutyl phthalate on rat Sertoli cells applying two mathematical models
    • Hu, Y.; Li, D.M.; Han, X.D. Analysis of combined effects of nonylphenol and Monobutyl phthalate on rat Sertoli cells applying two mathematical models. Food Chem. Toxicol. 2012, 50, 457-463.
    • (2012) Food Chem. Toxicol , vol.50 , pp. 457-463
    • Hu, Y.1    Li, D.M.2    Han, X.D.3
  • 48
    • 0018001339 scopus 로고
    • Simultaneous analysis of families of sigmoidal curves: Application to bioassay, radioligand assay, and physiological dose-response curves
    • DeLean, A.; Munson, P.J.; Rodbard, D. Simultaneous analysis of families of sigmoidal curves: Application to bioassay, radioligand assay, and physiological dose-response curves. Am. J. Physiol. 1978, 235, E97-E102.
    • (1978) Am. J. Physiol , vol.235
    • Delean, A.1    Munson, P.J.2    Rodbard, D.3
  • 49
    • 84863964069 scopus 로고    scopus 로고
    • Model of hormesis and its toxicity mechanism based on quorum sensing: A case study on the toxicity of sulfonamides to Photobacterium phosphoreum
    • Deng, Z.; Lin, Z.; Zou, X.; Yao, Z.; Tian, D.; Wang, D.; Yin, D. Model of hormesis and its toxicity mechanism based on quorum sensing: A case study on the toxicity of sulfonamides to Photobacterium phosphoreum. Environ. Sci. Technol. 2012, 46, 7746-7754.
    • (2012) Environ. Sci. Technol , vol.46 , pp. 7746-7754
    • Deng, Z.1    Lin, Z.2    Zou, X.3    Yao, Z.4    Tian, D.5    Wang, D.6    Yin, D.7
  • 51
    • 0030292217 scopus 로고    scopus 로고
    • Regulations for combined effects of pollutants: Consequences from risk assessment in aquatic toxicology
    • Altenburger, R.; Boedeker, W.; Faust, M.; Grimme, L.H. Regulations for combined effects of pollutants: Consequences from risk assessment in aquatic toxicology. Food Chem. Toxicol. 1996, 34, 1155-1157.
    • (1996) Food Chem. Toxicol , vol.34 , pp. 1155-1157
    • Altenburger, R.1    Boedeker, W.2    Faust, M.3    Grimme, L.H.4
  • 52
    • 78649905258 scopus 로고    scopus 로고
    • Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes
    • Petersen, K.; Tollefsen, K.E. Assessing combined toxicity of estrogen receptor agonists in a primary culture of rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 2011, 101, 186-195.
    • (2011) Aquat. Toxicol , vol.101 , pp. 186-195
    • Petersen, K.1    Tollefsen, K.E.2


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