Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis

Toxicology Letters

Volumn 206, Issue 2, 2011, Pages 210-217

  Frizzell, C ^a   Ndossi, D ^b,c   Verhaegen, S ^b   Dahl, E ^b   Eriksen, G ^d   Sorlie M ^b   Ropstad, E ^b   Muller, M ^e   Elliott, C T ^a   Connolly, L ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^c SOKOINE UNIVERSITY OF AGRICULTURE   (Tanzania)

^d NORWEGIAN VETERINARY INSTITUTE   (Norway)

^e UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Endocrine disruptor; H295R; Reporter gene assay; Sterodogenesis; Zearalenone

Indexed keywords

ALPHA ZEARALENOL; ANDROGEN; BETA ZEARALENOL; CELL NUCLEUS RECEPTOR; ENDOCRINE DISRUPTOR; ESTRADIOL; GESTAGEN; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; PROGESTERONE; TESTOSTERONE; ZEARALENONE;

ARTICLE; BINDING AFFINITY; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOCRINE SYSTEM; ESTROGEN ACTIVITY; HORMONE BINDING; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION; REPORTER GENE; STEROIDOGENESIS;

CELL LINE; CELL SURVIVAL; ENDOCRINE DISRUPTORS; ESTROGENS, NON-STEROIDAL; GENES, REPORTER; GONADAL STEROID HORMONES; HUMANS; HYDROCORTISONE; INHIBITORY CONCENTRATION 50; ISOMERISM; OSMOLAR CONCENTRATION; PROMOTER REGIONS, GENETIC; RECEPTORS, STEROID; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; ZEARALENONE; ZERANOL;

FUNGI; FUSARIUM;

EID: 80052086743     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.07.015     Document Type: Article

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