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Volumn 557, Issue 1, 2004, Pages 19-27

Ochratoxin A and zearalenone: A comparative study on genotoxic effects and cell death induced in bovine lymphocytes

Author keywords

Apoptosis; Cell cultures; Chromosome aberrations; Mitotic index; Mycotoxins; Sister chromatid exchanges

Indexed keywords

MYCOTOXIN; OCHRATOXIN; ZEARALENONE;

EID: 0345791439     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2003.09.009     Document Type: Article
Times cited : (142)

References (47)
  • 6
    • 0035888268 scopus 로고    scopus 로고
    • Toxicity, metabolism, and impact of mycotoxins on humans and animals
    • Hussein H.S., Brasel J.M. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology. 167:2001;101-134.
    • (2001) Toxicology , vol.167 , pp. 101-134
    • Hussein, H.S.1    Brasel, J.M.2
  • 7
    • 0024369396 scopus 로고
    • Mechanism of ochratoxin A-induced immunosuppression
    • Lea T., Steien K., Størmer C. Mechanism of ochratoxin A-induced immunosuppression. Mycopathologia. 107:1989;153-159.
    • (1989) Mycopathologia , vol.107 , pp. 153-159
    • Lea, T.1    Steien, K.2    Størmer, C.3
  • 8
    • 0024723238 scopus 로고
    • Risk assessment of the mycotoxin ochratoxin a
    • Kuiper-Goodman T., Scott P.M. Risk assessment of the mycotoxin ochratoxin A. Biom. Environ. Sci. 2:1989;179-248.
    • (1989) Biom. Environ. Sci. , vol.2 , pp. 179-248
    • Kuiper-Goodman, T.1    Scott, P.M.2
  • 10
    • 0031733769 scopus 로고    scopus 로고
    • The role of ochratoxin a as a possible cause of Balkan endemic nephropathy and its risk evaluation
    • Stoev S.D. The role of ochratoxin A as a possible cause of Balkan endemic nephropathy and its risk evaluation. Vet. Hum. Toxicol. 40:1998;352-360.
    • (1998) Vet. Hum. Toxicol. , vol.40 , pp. 352-360
    • Stoev, S.D.1
  • 11
    • 0023263175 scopus 로고
    • Endemic nephropathy and urinary tract tumours in the Balkan
    • Castegnaro M., Chernozemski I.N. Endemic nephropathy and urinary tract tumours in the Balkan. Cancer Res. 47:1987;3608-3609.
    • (1987) Cancer Res. , vol.47 , pp. 3608-3609
    • Castegnaro, M.1    Chernozemski, I.N.2
  • 13
    • 43949159005 scopus 로고
    • Effects of zearalenone or glucosinolates in the diet on reproduction in sows: A review
    • Etienne M., Dourmad J.-Y. Effects of zearalenone or glucosinolates in the diet on reproduction in sows: a review. Livestock Prod. Sci. 40:1994;99-113.
    • (1994) Livestock Prod. Sci. , vol.40 , pp. 99-113
    • Etienne, M.1    Dourmad, J.-Y.2
  • 14
    • 0037186863 scopus 로고    scopus 로고
    • Update of survey, regulation and toxic effects of mycotoxins in Europe
    • Creppy E.E. Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicol. Lett. 127:2002;19-28.
    • (2002) Toxicol. Lett. , vol.127 , pp. 19-28
    • Creppy, E.E.1
  • 15
    • 0014289987 scopus 로고
    • Detection of a fungal estrogen (F-2) in hay associated with infertility in dairy cattle
    • Mirocha C.J., Harrison J., Nichols A.A., McClintock M. Detection of a fungal estrogen (F-2) in hay associated with infertility in dairy cattle. Appl. Environ. Microbiol. 16:1968;797-798.
    • (1968) Appl. Environ. Microbiol. , vol.16 , pp. 797-798
    • Mirocha, C.J.1    Harrison, J.2    Nichols, A.A.3    McClintock, M.4
  • 16
    • 0034819429 scopus 로고    scopus 로고
    • Toxic effects of the mycotoxin zearalenone and its derivatives on in vitro maturation of bovine oocytes and 17β-estradiol levels in mural granulosa cell cultures
    • Minervini F., Dell'Aquila M.E., Maritato F., Minoia P., Visconti A. Toxic effects of the mycotoxin zearalenone and its derivatives on in vitro maturation of bovine oocytes and 17β-estradiol levels in mural granulosa cell cultures. Toxicol. In Vitro. 15:2001;489-495.
    • (2001) Toxicol. in Vitro , vol.15 , pp. 489-495
    • Minervini, F.1    Dell'Aquila, M.E.2    Maritato, F.3    Minoia, P.4    Visconti, A.5
  • 17
    • 0017880759 scopus 로고
    • Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins
    • Wehner F., Marasas W., Thiel P. Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins. Appl. Environ. Microbiol. 35:1978;659-662.
    • (1978) Appl. Environ. Microbiol. , vol.35 , pp. 659-662
    • Wehner, F.1    Marasas, W.2    Thiel, P.3
  • 18
    • 0028839564 scopus 로고
    • Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues
    • Pfhol-Leszkowicz A., Ghédira Chékir L., Bacha H. Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissues. Carcinogenesis. 16:1995;2315-2320.
    • (1995) Carcinogenesis , vol.16 , pp. 2315-2320
    • Pfhol-Leszkowicz, A.1    Ghédira Chékir, L.2    Bacha, H.3
  • 21
    • 0020696276 scopus 로고
    • Genotoxicity of Fusarium mycotoxins (nivalenon, fusarenon-X, T2-toxin and zearalenone) in Chinese hamster V79-E cells in vitro
    • Thust R., Kneist S., Huhne V. Genotoxicity of Fusarium mycotoxins (nivalenon, fusarenon-X, T2-toxin and zearalenone) in Chinese hamster V79-E cells in vitro. Arch. Geschwulsforsch. 53:1983;9-15.
    • (1983) Arch. Geschwulsforsch. , vol.53 , pp. 9-15
    • Thust, R.1    Kneist, S.2    Huhne, V.3
  • 23
    • 0024199948 scopus 로고
    • Natural occurrence and clastogenic effects of nivalenol, deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in corn from high risk area of esophageal cancer
    • Hsia C.C., Wu J.L., Lu X.Q., Li Y.S. Natural occurrence and clastogenic effects of nivalenol, deoxynivalenol, 3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, and zearalenone in corn from high risk area of esophageal cancer. Cancer Detect. Prevent. 13:1988;79-86.
    • (1988) Cancer Detect. Prevent. , vol.13 , pp. 79-86
    • Hsia, C.C.1    Wu, J.L.2    Lu, X.Q.3    Li, Y.S.4
  • 24
    • 0035025541 scopus 로고    scopus 로고
    • Genotoxic evaluation for the estrogenic mycotoxin zearalenone
    • El-Makawy A., Hassanane M.S., Abd Alla E.S. Genotoxic evaluation for the estrogenic mycotoxin zearalenone. Reprod. Nutr. Dev. 41:2001;79-89.
    • (2001) Reprod. Nutr. Dev. , vol.41 , pp. 79-89
    • El-Makawy, A.1    Hassanane, M.S.2    Abd Alla, E.S.3
  • 25
    • 85030918032 scopus 로고    scopus 로고
    • International Agency for Research on Cancer, IARC Monographs on the evaluation of carcinogenic risks to humans, vol. 56, Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins, Lyon, 1993
    • International Agency for Research on Cancer, IARC Monographs on the evaluation of carcinogenic risks to humans, vol. 56, Some naturally occurring substances: food items and constituents, heterocyclic aromatic amines and mycotoxins, Lyon, 1993.
  • 26
    • 0028276212 scopus 로고
    • Structure-activity studies in E. coli strains on ochratoxin a (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites
    • Malaveille C., Brun G., Bartsch H. Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites. Mutat. Res. 307:1994;141-147.
    • (1994) Mutat. Res. , vol.307 , pp. 141-147
    • Malaveille, C.1    Brun, G.2    Bartsch, H.3
  • 27
    • 0032699716 scopus 로고    scopus 로고
    • Genotoxicity of ochratoxin a by Salmonella mutagenicity test after bioactivation by mouse kidney microsomes
    • Obrecht-Pfumio S., Chassat T., Dirheimer G., Marzin D. Genotoxicity of ochratoxin A by Salmonella mutagenicity test after bioactivation by mouse kidney microsomes. Mutat. Res. 446:1999;95-102.
    • (1999) Mutat. Res. , vol.446 , pp. 95-102
    • Obrecht-Pfumio, S.1    Chassat, T.2    Dirheimer, G.3    Marzin, D.4
  • 28
    • 0024996262 scopus 로고
    • Induction of characteristic chromosomal aberrations, particularly X-trisomy, in cultured human lymphocytes treated by ochratoxin A, a mycotoxin implicated in Balkan endemic nephropathy
    • Manolova Y., Manolov G., Parvanova L., Petkova-Bocharova T., Castegnaro M., Chermozemski I.N. Induction of characteristic chromosomal aberrations, particularly X-trisomy, in cultured human lymphocytes treated by ochratoxin A, a mycotoxin implicated in Balkan endemic nephropathy. Mutat. Res. 231:1990;143-149.
    • (1990) Mutat. Res. , vol.231 , pp. 143-149
    • Manolova, Y.1    Manolov, G.2    Parvanova, L.3    Petkova-Bocharova, T.4    Castegnaro, M.5    Chermozemski, I.N.6
  • 29
    • 0028936253 scopus 로고
    • Sister chromatid exchange frequency in cultured isolated porcine urinary bladder epithelial cells (PUBEC) treated with ochratoxin a and alpha
    • Föllman W., Hillebrand I.E., Creppy E.E., Bolt H.M. Sister chromatid exchange frequency in cultured isolated porcine urinary bladder epithelial cells (PUBEC) treated with ochratoxin A and alpha. Arch. Toxicol. 69:1995;280-286.
    • (1995) Arch. Toxicol. , vol.69 , pp. 280-286
    • Föllman, W.1    Hillebrand, I.E.2    Creppy, E.E.3    Bolt, H.M.4
  • 30
    • 0030925538 scopus 로고    scopus 로고
    • Induction of micronuclei with ochratoxin a in ovine seminal vesicle cell cultures
    • Degen G.H., Gerber M.M., Obrecht-Pfumio S., Dirheimer G. Induction of micronuclei with ochratoxin a in ovine seminal vesicle cell cultures. Arch. Toxicol. 71:1997;365-371.
    • (1997) Arch. Toxicol. , vol.71 , pp. 365-371
    • Degen, G.H.1    Gerber, M.M.2    Obrecht-Pfumio, S.3    Dirheimer, G.4
  • 31
    • 0030942015 scopus 로고    scopus 로고
    • Retinol, ascorbic acid and α-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin a and zearalenone
    • Grosse Y., Chekir-Ghedira L., Huc A., Obrecht-Pfumio S., Dirheimer G., Bacha H., Pfohl-Leszkowicz A. Retinol, ascorbic acid and α-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone. Cancer Lett. 114:1997;225-229.
    • (1997) Cancer Lett. , vol.114 , pp. 225-229
    • Grosse, Y.1    Chekir-Ghedira, L.2    Huc, A.3    Obrecht-Pfumio, S.4    Dirheimer, G.5    Bacha, H.6    Pfohl-Leszkowicz, A.7
  • 35
  • 36
    • 85030931126 scopus 로고    scopus 로고
    • F.E. Eldridge, Cytogenetics of livestock, The AVI Publishing Company Inc., Westpoint, Connecticut, 1985, pp. 115-187
    • F.E. Eldridge, Cytogenetics of livestock, The AVI Publishing Company Inc., Westpoint, Connecticut, 1985, pp. 115-187.
  • 38
    • 0033613855 scopus 로고    scopus 로고
    • Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression
    • Salvemini F., Franzé A., Iervolino A., Filosa S., Salzano S., Ursini M.V. Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression. J. Biol. Chem. 274:1999;2750-2757.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2750-2757
    • Salvemini, F.1    Franzé, A.2    Iervolino, A.3    Filosa, S.4    Salzano, S.5    Ursini, M.V.6
  • 39
    • 85030934116 scopus 로고    scopus 로고
    • H. Pattersson, K.H. Kiessling, P. Cisluk, Degradation of ochratoxin A in rumen, in: Presented at Vth International IUPAC Symposium on Mycotoxins and Phytotoxins, Vienna, Austria, 1982, pp. 313-316
    • H. Pattersson, K.H. Kiessling, P. Cisluk, Degradation of ochratoxin A in rumen, in: Presented at Vth International IUPAC Symposium on Mycotoxins and Phytotoxins, Vienna, Austria, 1982, pp. 313-316.
  • 40
    • 0033045711 scopus 로고    scopus 로고
    • Inactivation of ochratoxin in ruminal fluid with variation of pH-value and fermentation parameters in an in vitro system
    • Opzinar H., Augonyte G., Drochner W. Inactivation of ochratoxin in ruminal fluid with variation of pH-value and fermentation parameters in an in vitro system. Environ. Toxicol. Pharmacol. 7:1999;1-9.
    • (1999) Environ. Toxicol. Pharmacol. , vol.7 , pp. 1-9
    • Opzinar, H.1    Augonyte, G.2    Drochner, W.3
  • 41
    • 85030923575 scopus 로고    scopus 로고
    • M. Olsen, Metabolism of zearalenone in farm animals, in: J. Chelkowski (Ed.), Fusarium: Mycotoxins, Taxonomy and Pathogenicity, Elsevier, Amsterdam, 1989, pp. 167-177
    • M. Olsen, Metabolism of zearalenone in farm animals, in: J. Chelkowski (Ed.), Fusarium: Mycotoxins, Taxonomy and Pathogenicity, Elsevier, Amsterdam, 1989, pp. 167-177.
  • 43
    • 0034768453 scopus 로고    scopus 로고
    • Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line
    • Horvath A., Upham B.L., Ganev V., Trosko J.E. Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line. Toxicon. 40:2002;273-282.
    • (2002) Toxicon , vol.40 , pp. 273-282
    • Horvath, A.1    Upham, B.L.2    Ganev, V.3    Trosko, J.E.4
  • 44
    • 0025801648 scopus 로고
    • Cytogenetic biomonitoring of an Italian population exposed to pesticides: Chromosome aberrations and sister chromatid exchange analysis in peripheral blood lymphocytes
    • De Ferrari M., Artuso M., Bonassi S., Monatti S., Cavalieri Z., Pescatore D., Martini E., Pisano V., Abbondandolo A. Cytogenetic biomonitoring of an Italian population exposed to pesticides: chromosome aberrations and sister chromatid exchange analysis in peripheral blood lymphocytes. Mutat. Res. 260:1991;105-113.
    • (1991) Mutat. Res. , vol.260 , pp. 105-113
    • De Ferrari, M.1    Artuso, M.2    Bonassi, S.3    Monatti, S.4    Cavalieri, Z.5    Pescatore, D.6    Martini, E.7    Pisano, V.8    Abbondandolo, A.9
  • 45
    • 0028237312 scopus 로고
    • Genotoxic effects of the carbamate insecticide methomyl. I. in vitro studies with pure compound and the technical formulation "lannate 25"
    • Bonatti S., Bolognesi C., Degan P., Abbondandolo A. Genotoxic effects of the carbamate insecticide methomyl. I. In vitro studies with pure compound and the technical formulation "Lannate 25" Environ. Mol. Mutagen. 23:1994;306-311.
    • (1994) Environ. Mol. Mutagen. , vol.23 , pp. 306-311
    • Bonatti, S.1    Bolognesi, C.2    Degan, P.3    Abbondandolo, A.4
  • 46
    • 0031879838 scopus 로고    scopus 로고
    • Cytogenetic damage and induction of pro-oxidant state in human lymphocytes exposed in vitro to gliphosate, vinclozolin, atrazine, and DPX-E9636
    • Lioi M.B., Scarfì M.R., Santoro A., Barbieri R., Zeni O., Salvemini F., Di Berardino D., Ursini M.V. Cytogenetic damage and induction of pro-oxidant state in human lymphocytes exposed in vitro to gliphosate, vinclozolin, atrazine, and DPX-E9636. Environ. Mol. Mutagen. 32:1998;39-46.
    • (1998) Environ. Mol. Mutagen. , vol.32 , pp. 39-46
    • Lioi, M.B.1    Scarfì, M.R.2    Santoro, A.3    Barbieri, R.4    Zeni, O.5    Salvemini, F.6    Di Berardino, D.7    Ursini, M.V.8
  • 47
    • 0035120348 scopus 로고    scopus 로고
    • Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells
    • Hamed S., Foster J.S., Bukovsky A., Wimalasena J. Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen zearalenone-induced cell-cycle progression in MCF-7 cells. Mol. Carcinog. 30:2001;88-98.
    • (2001) Mol. Carcinog. , vol.30 , pp. 88-98
    • Hamed, S.1    Foster, J.S.2    Bukovsky, A.3    Wimalasena, J.4


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