Co-exposure of Fusarium mycotoxins: In vitro myelotoxicity assessment on human hematopoietic progenitors

Toxicon

Volumn 60, Issue 6, 2012, Pages 1171-1179

  Ficheux, A S ^a   Sibiril, Y ^b   Parent Massin, D ^a,c  

^a UFR SCIENCES ET TECHNIQUES   (France)

^b FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Co exposure; Fusariotoxins; Human hematopoietic progenitors; In vitro; Myelotoxicity

Indexed keywords

BEAUVERICIN; ENNIATIN; FUMONISIN B1; MYCOTOXIN; T 2 TOXIN; VOMITOXIN; ZEARALENONE;

ARTICLE; BONE MARROW TOXICITY; CLONOGENIC ASSAY; COLONY FORMING UNIT GM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY TEST; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LONG TERM EXPOSURE; PRIORITY JOURNAL; TOXIN ANALYSIS; TOXIN STRUCTURE;

CELLS, CULTURED; DEPSIPEPTIDES; FUMONISINS; FUSARIUM; GRANULOCYTE-MACROPHAGE PROGENITOR CELLS; HUMANS; MYCOTOXINS; T-2 TOXIN; TOXICITY TESTS; TRICHOTHECENES; ZEARALENONE;

FUSARIUM;

EID: 84865572978     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2012.08.001     Document Type: Article

References (39)

1. Bouslimi A., Bouaziz C., Ayed-Boussema I., Hassen W., Bacha H. Individual and combined effects of ochratoxin A and citrinin on viability and DNA fragmentation in cultured Vero cells and on chromosome aberrations in mice bone marrow cells. Toxicology 2008, 251:1-7.
2. Cavret S., Lecoeur S. Fusariotoxin transfer in animal. Food Chem. Toxicol. 2006, 44:444-453.
3. Corcuera L.A., Arbillaga L., Vettorazzi A., Azqueta A., López de Cerain A. Ochratoxin A reduces aflatoxin B1 induced DNA damage detected by the comet assay in Hep G2 cells. Food Chem. Toxicol. 2011, 49:2883-2889.
4. Dombrink-Kurtzman M.A. Fumonisin and beauvericin induce apoptosis in turkey peripheral blood lymphocytes. Mycopathologia 2003, 156:357-364.
5. Ficheux A.S., Sibiril Y., Le Garrec R., Parent-Massin D. In vitro myelotoxicity assessment of the emerging mycotoxins Beauvericin, Enniatin b and Moniliformin on human hematopoietic progenitors. Toxicon 2012, 59:182-191.
6. Froquet R., Sibiril Y., Parent-Massin D. Trichothecene toxicity on human megakaryocyte progenitors (CFU-MK). Hum. Exp. Toxicol. 2001, 20:84-89.
7. Gammelsrud A., Solhaug A., Dendelé B., Sandberg W.J., Ivanova L., Kocbach Bolling A., Lagadic-Gossmann D., Refsnes M., Becher R., Eriksen G., Holme J.A. Enniatin B-induced cell death and inflammatory responses in RAW 267.4 murine macrophages. Toxicol. Appl. Pharmacol. 2012, 261:74-87.
8. Grenier B., Oswald I. Mycotoxin co-contamination of food and feed: meta-analysis of publications describing toxicological interactions. World Mycotox. J. 2011, 4:285-313.
9. Jestoi M. Emerging Fusarium-mycotoxins fusaproliferin, beauvericin, enniatins, and moniliformin-a review. Crit. Rev. Food Sci. Nutr. 2008, 48:21-49.
10. Jestoi M., Rokka M., Yli-Mattila T., Parikka P., Rizzo A., Peltonen K. Presence and concentrations of the Fusarium-related mycotoxins Beauvericin, Enniatins and Moniliformin in Finnish grain samples. Food Addit. Contam. 2004, 21:794-802.
11. Jow G.M., Chou C.J., Chen B.F., Tsai J.H. Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium. Cancer Lett. 2004, 216:165-173.
12. Klaric M.S., Darabos D., Rozgaj R., Kasuba V., Pepeljnjak S. Beauvericin and ochratoxin A genotoxicity evaluated using the alkaline comet assay: single and combined genotoxic action. Arch. Toxicol. 2010, 84:641-650.
13. Klaric M.S., Pepeljnjak S., Rozgaj R. Genotoxicity of Fumonisin B1, Beauvericin and Ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. Croat. Chem. Acta 2008, 81:139-146.
14. Klaric M.S., Rumora L., Ljubanovic D., Pepeljnjak S. Cytotoxicity and apoptosis induced by fumonisin B1, beauvericin and ochratoxin A in porcine kidney PK15 cells: effects of individual and combined treatment. Arch. Toxicol. 2008, 82:247-255.
15. Klaric M.S., Zeljezic D., Rumora L., Peraica M., Pepeljnjak S., Domijan A.M. A potential role of calcium in apoptosis and aberrant chromatin forms in porcine kidney PK15 cells induced by individual and combined ochratoxin A and citrinin. Arch. Toxicol. 2012, 86:97-107.
16. Kokkonen M., Ojala L., Parikka P., Jestoi M. Mycotoxin production of selected Fusarium species at different culture conditions. Int. J. Food Microbiol. 2010, 143:17-25.
17. Kouadio J.H., Dano S.D., Moukha S., Mobio T.A., Creppy E.E. Effects of combinations of Fusarium mycotoxins on the inhibition of macromolecular synthesis, malondialdehyde levels, DNA methylation and fragmentation, and viability in Caco-2 cells. Toxicon 2007, 49:306-317.
18. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. Comparison of toxicity induced by T-2 toxin on human and rat granulo-monocytic progenitors with an in vitro model. Hum. Exp. Toxicol. 1995, 14:672-678.
19. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. Comparison of toxicity induced by HT-2 toxin on human and rat granulo-monocytic progenitors with an in vitro model. Hum. Exp. Toxicol. 1996, 15:208-213.
20. Lautraite S., Parent-Massin D., Rio B., Hoellinger H. In vitro toxicity induced by deoxynivalenol (DON) on human and rat granulo-monocytic progenitors. Cell Biol. Toxicol. 1997, 175-183.
21. Lautraite S., Rio B., Guinard J., Parent-Massin D. In vitro effects of diacetoxyscirpenol (DAS) on human and rat granulo-monocytic progenitors. Mycopathologia 1997, 140:59-64.
22. Le Dréan G., Auffret M., Batina P., Arnold F., Sibiril Y., Arzur D., Parent-Massin D. Myelotoxicity of trichothecenes and apoptosis: an in vitro study on human cord blood CD34+ hematopoietic progenitor. Toxicol. In Vitro 2005, 19:1015-1024.
23. Lin H.I., Lee Y.J., Chen B.F., Tsai M.C., Lu J.L., Chou C.J., Jow G.M. Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells. Cancer Lett. 2005, 230:248-259.
24. Luongo D., De Luna R., Russo R., Severino L. Effects of four Fusarium toxins (fumonisin B(1), alpha-zearalenol, nivalenol and deoxynivalenol) on porcine whole-blood cellular proliferation. Toxicon 2008, 52:156-162.
25. Luongo D., Severino L., Bergamo P., De Luna R., Lucisano A., Rossi M. Interactive effects of fumonisin B1 and alpha-zearalenol on proliferation and cytokine expression in Jurkat T cells. Toxicol. In Vitro 2006, 20:1403-1410.
26. Marzocco S., Russo R., Bianco G., Autore G., Severino L. Pro-apoptotic effects of nivalenol and deoxynivalenol trichothecenes in J774A.1 murine macrophages. Toxicol. Lett. 2009, 189:21-26.
27. Monbaliu S., Van Poucke C., Detavernier C., Dumoulin F., Van De Velde M., Schoeters E., Van Dyck S., Averkieva O., Van Peteghem C., De Saeger S. Occurrence of mycotoxins in feed as analyzed by a multi-mycotoxin LC-MS/MS method. J. Agric. Food Chem. 2010, 58:66-71.
28. Pessina A., Albella B., Bueren J., Brantom P., Casati S., Gribaldo L., Croera C., Gagliardi G., Foti P., Parchment R., Parent-Massin D., Sibiril Y., Schoeters G., Van Den Heuvel R. Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay. Toxicol. In Vitro 2001, 15:729-740.
29. Placinta C.M., D'Mello J.P.F., Macdonald A.M.C. A review of worldwide contamination of cereal grains and animal feed with Fusarium mycotoxins. Anim. Feed Sci. Technol. 1999, 78:21-37.
30. Rio B., Lautraite S., Parent-Massin D. In vitro toxicity of trichothecenes on human erythroblastic progenitors. Hum. Exp. Toxicol. 1997, 16:673-679.
31. Rodrigues, I., Naeher, K., 2010. Biomin Survey 2010: Mycotoxins Inseparable from Animal Commodities and Feed. Biomin Mycotoxin Survey 2010. 2.
32. Ruiz M.J., Franzova P., Juan-García A., Font G. Toxicological interactions between the mycotoxins beauvericin, deoxynivalenol and T-2 toxin in CHO-K1 cells in vitro. Toxicon 2011, 58:315-326.
33. Ruiz M.J., Macáková P., Juan-García A., Font G. Cytotoxic effects of mycotoxin combinations in mammalian kidney cells. Food Chem. Toxicol. 2011, 49:2718-2724.
34. Tajima O., Schoen E.D., Feron V.K., Groten J.P. Statistically designed experiments in a tiered approach to screen mixtures of Fusarium mycotoxins for possible interactions. Food Chem. Toxicol. 2002, 40:685-695.
35. Thuvander A., Wikman C., Gadhasson I. In vitro exposure of human lymphocytes to trichothecenes: individual variation in sensitivity and effects of combined exposure on lymphocyte function. Food Chem. Toxicol. 1999, 37:639-648.
36. Tomoda H., Huang X.-H., Cao J., Nishida H., Nagao R., Okuda S., Tanaka H., Omura S., Arai H., Inoue K. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J. Antibiot. 1992, 45:1626-1632.
37. Wätjen W., Debbab A., Hohlfeld A., Chovolou Y., Kampkötter A., Edrada R.A., Ebel R., Hakiki A., Mosaddak M., Totzke F., Kubbutat M., Wätjen P.P. Enniatins A1, B and B1 from an endophytic strain of Fusarium tricinctum induce apoptotic cell death in H4IIE hepatoma cells accompanied by inhibition of ERK phosphorylation. Mol. Nutr. Food Res. 2009, 53:431-440.
38. Weber F., Freudinger R., Schwerdt G., Gekle M. A rapid screening method to test apoptotic synergisms of ochratoxin A with other nephrotoxic substances. Toxicol. In Vitro 2005, 19:135-143.
39. Zhu L., Yuan H., Guo C., Lu Y., Deng S., Yang Y., Wei Q., Wen L., He Z. Zearalenone induces apoptosis and necrosis in porcine granulosa cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway. J. Cell. Physiol. 2012, 227:1814-1820.