Novel approaches for the design and discovery of quorum-sensing inhibitors

Expert Opinion on Drug Discovery

Volumn 9, Issue 4, 2014, Pages 353-366

  Scutera, Sara ^a   Zucca, Mario ^a   Savoia, Dianella ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Antibodies; Autoinducers; Pseudomonas aeruginosa; Quorum sensing; Receptors; Staphylococcus aureus; Virulence factors

Indexed keywords

ANTIBIOTIC AGENT; ARYLDIALKYLPHOSPHATASE; BACTERIUM ANTIBODY; CHLORAMPHENICOL; FARNESOL; MOLECULAR SCAFFOLD; N ACYLHOMOSERINE LACTONE; NALIDIXIC ACID; PROBIOTIC AGENT; QUORUM SENSING INHIBITOR; RIFAMPICIN; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; SINEFUNGIN; SPECTINOMYCIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; BACILLUS MEGATERIUM; BACTERIAL VIRULENCE; BIOENGINEERING; BIOSYNTHESIS; BURKHOLDERIA PSEUDOMALLEI; CANDIDA ALBICANS; CELL METABOLISM; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; COMPUTER AIDED DESIGN; DNA DAMAGE; DNA MODIFICATION; DRUG DESIGN; ENZYMATIC DEGRADATION; ESCHERICHIA COLI; GENE CONTROL; HAMAMELIS; HIGH THROUGHPUT SCREENING; HUMAN; INNATE IMMUNITY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROTECHNOLOGY; NANOTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; REACTION OPTIMIZATION; REVIEW; RHODOCOCCUS ERYTHROPOLIS; SIGNAL DETECTION; STAPHYLOCOCCUS AUREUS; ANIMAL; BACTERIAL PHENOMENA AND FUNCTIONS; DRUG EFFECTS; METABOLISM;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PHYSIOLOGICAL PHENOMENA; BACTERIAL PROTEINS; DRUG DESIGN; HUMANS; QUORUM SENSING;

EID: 84896908713     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2014.894974     Document Type: Review

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