메뉴 건너뛰기




Volumn 7, Issue , 2013, Pages

Rule-based regulatory and metabolic model for Quorum sensing in P. aeruginosa

Author keywords

Boolean network; Gene regulatory network; Inhibitor; Multi level logical approach; Pqs system; Pseudomonas aeruginosa; Quorum sensing

Indexed keywords

BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 84882319203     PISSN: None     EISSN: 17520509     Source Type: Journal    
DOI: 10.1186/1752-0509-7-81     Document Type: Article
Times cited : (15)

References (46)
  • 1
    • 33644849230 scopus 로고    scopus 로고
    • Quorum-sensing inhibitors as anti-pathogenic drugs
    • Rasmussen T, Givskov M, et al. Quorum-sensing inhibitors as anti-pathogenic drugs. IJMM 2006, 296:149.
    • (2006) IJMM , vol.296 , pp. 149
    • Rasmussen, T.1    Givskov, M.2
  • 3
    • 0033862847 scopus 로고    scopus 로고
    • Bacterial quorum sensing in pathogenic relationships
    • 10.1128/IAI.68.9.4839-4849.2000, 101676, 10948095
    • De Kievit T, Iglewski B. Bacterial quorum sensing in pathogenic relationships. Infect Immun 2000, 68:4839-4849. 10.1128/IAI.68.9.4839-4849.2000, 101676, 10948095.
    • (2000) Infect Immun , vol.68 , pp. 4839-4849
    • De Kievit, T.1    Iglewski, B.2
  • 5
    • 0028953276 scopus 로고
    • A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa
    • 10.1073/pnas.92.5.1490, 42545, 7878006
    • Pearson J, Passador L, Iglewski B, Greenberg E. A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa. Proc Natl Acad Sci 1995, 92:1490. 10.1073/pnas.92.5.1490, 42545, 7878006.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 1490
    • Pearson, J.1    Passador, L.2    Iglewski, B.3    Greenberg, E.4
  • 6
    • 0033613179 scopus 로고    scopus 로고
    • Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa
    • 10.1073/pnas.96.20.11229, 18016, 10500159
    • Pesci E, Milbank J, Pearson J, McKnight S, Kende A, Greenberg E, Iglewski B. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa. Proc Natl Acad Sci 1999, 96:11229. 10.1073/pnas.96.20.11229, 18016, 10500159.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 11229
    • Pesci, E.1    Milbank, J.2    Pearson, J.3    McKnight, S.4    Kende, A.5    Greenberg, E.6    Iglewski, B.7
  • 7
    • 0028967496 scopus 로고
    • Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy
    • 176640, 7836299
    • Seed P, Passador L, Iglewski B. Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy. J Bacteriol 1995, 177:654-659. 176640, 7836299.
    • (1995) J Bacteriol , vol.177 , pp. 654-659
    • Seed, P.1    Passador, L.2    Iglewski, B.3
  • 8
    • 0032949363 scopus 로고    scopus 로고
    • RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa
    • 93631, 10094696
    • De Kievit T, Seed P, Nezezon J, Passador L, Iglewski B. RsaL, a novel repressor of virulence gene expression in Pseudomonas aeruginosa. J Bacteriol 1999, 181:2175-2184. 93631, 10094696.
    • (1999) J Bacteriol , vol.181 , pp. 2175-2184
    • De Kievit, T.1    Seed, P.2    Nezezon, J.3    Passador, L.4    Iglewski, B.5
  • 9
    • 0027299747 scopus 로고
    • Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication
    • 10.1126/science.8493556, 8493556
    • Passador L, Cook J, Gambello M, Rust L, Iglewski B. Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication. Science 1993, 260:1127-1130. 10.1126/science.8493556, 8493556.
    • (1993) Science , vol.260 , pp. 1127-1130
    • Passador, L.1    Cook, J.2    Gambello, M.3    Rust, L.4    Iglewski, B.5
  • 10
    • 0029023052 scopus 로고
    • Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa
    • 10.1073/pnas.92.14.6424, 41530, 7604006
    • Ochsner U, Reiser J. Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa. Proc Natl Acad Sci 1995, 92:6424. 10.1073/pnas.92.14.6424, 41530, 7604006.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 6424
    • Ochsner, U.1    Reiser, J.2
  • 11
    • 0030985995 scopus 로고    scopus 로고
    • Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa
    • 179088, 9150205
    • Pesci E, Pearson J, Seed P, Iglewski B. Regulation of las and rhl quorum sensing in Pseudomonas aeruginosa. J Bacteriol 1997, 179:3127-3132. 179088, 9150205.
    • (1997) J Bacteriol , vol.179 , pp. 3127-3132
    • Pesci, E.1    Pearson, J.2    Seed, P.3    Iglewski, B.4
  • 12
    • 0030919474 scopus 로고    scopus 로고
    • The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase
    • 10.1046/j.1365-2958.1997.3291701.x, 9159518
    • Reimmann C, Beyeler M, Latifi A, Winteler H, Foglino M, Lazdunski A, Haas D. The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. Mol Microbiol 1997, 24:309-319. 10.1046/j.1365-2958.1997.3291701.x, 9159518.
    • (1997) Mol Microbiol , vol.24 , pp. 309-319
    • Reimmann, C.1    Beyeler, M.2    Latifi, A.3    Winteler, H.4    Foglino, M.5    Lazdunski, A.6    Haas, D.7
  • 13
    • 0030923758 scopus 로고    scopus 로고
    • Vfr controls quorum sensing in Pseudomonas aeruginosa
    • 179201, 9190808
    • Albus A, Pesci E, Runyen-Janecky L, West S, Iglewski B. Vfr controls quorum sensing in Pseudomonas aeruginosa. J Bacteriol 1997, 179:3928-3935. 179201, 9190808.
    • (1997) J Bacteriol , vol.179 , pp. 3928-3935
    • Albus, A.1    Pesci, E.2    Runyen-Janecky, L.3    West, S.4    Iglewski, B.5
  • 14
    • 0027997539 scopus 로고
    • Isolation, characterization, and expression in Escherichia coli of the Pseudomonas aeruginosa rhlAB genes encoding a rhamnosyltransferase involved in rhamnolipid biosurfactant synthesis
    • Ochsner U, Fiechter A, Reiser J. Isolation, characterization, and expression in Escherichia coli of the Pseudomonas aeruginosa rhlAB genes encoding a rhamnosyltransferase involved in rhamnolipid biosurfactant synthesis. J Biological Chem 1994, 269:19787.
    • (1994) J Biological Chem , vol.269 , pp. 19787
    • Ochsner, U.1    Fiechter, A.2    Reiser, J.3
  • 15
    • 0037215605 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa rhlAB operon is not expressed during the logarithmic phase of growth even in the presence of its activator RhlR and the autoinducer N-butyryl-homoserine lactone
    • 10.1128/JB.185.1.377-380.2003, 141836, 12486077
    • Medina G, Juárez K, Soberón-Chávez G. The Pseudomonas aeruginosa rhlAB operon is not expressed during the logarithmic phase of growth even in the presence of its activator RhlR and the autoinducer N-butyryl-homoserine lactone. J Bacteriol 2003, 185:377-380. 10.1128/JB.185.1.377-380.2003, 141836, 12486077.
    • (2003) J Bacteriol , vol.185 , pp. 377-380
    • Medina, G.1    Juárez, K.2    Soberón-Chávez, G.3
  • 16
    • 0033679209 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa rhamnolipids: biosynthesis and potential applications
    • 10.1007/s002530000443, 11131386
    • Maier R, Soberon-Chavez G. Pseudomonas aeruginosa rhamnolipids: biosynthesis and potential applications. Appl Microbiol Biotechnol 2000, 54:625-633. 10.1007/s002530000443, 11131386.
    • (2000) Appl Microbiol Biotechnol , vol.54 , pp. 625-633
    • Maier, R.1    Soberon-Chavez, G.2
  • 17
    • 0842320989 scopus 로고    scopus 로고
    • Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication
    • 10.1073/pnas.0307694100, 337054, 14739337
    • Déziel E, Lépine F, Milot S, He J, Mindrinos M, Tompkins R, Rahme L. Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci 2004, 101:1339-1344. 10.1073/pnas.0307694100, 337054, 14739337.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 1339-1344
    • Déziel, E.1    Lépine, F.2    Milot, S.3    He, J.4    Mindrinos, M.5    Tompkins, R.6    Rahme, L.7
  • 18
    • 33745269562 scopus 로고    scopus 로고
    • Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry
    • Xiao G, He J, Rahme L. Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry. Microbiol 2006, 152:1679-1686.
    • (2006) Microbiol , vol.152 , pp. 1679-1686
    • Xiao, G.1    He, J.2    Rahme, L.3
  • 19
    • 79953716518 scopus 로고    scopus 로고
    • Biosynthesis of 2-Alkyl-4 (1H)-Quinolones in Pseudomonas aeruginosa: Potential for therapeutic interference with pathogenicity
    • 10.1002/cbic.201100014, 21425231
    • Pistorius D, Ullrich A, Lucas S, Hartmann R, Kazmaier U, Müller R. Biosynthesis of 2-Alkyl-4 (1H)-Quinolones in Pseudomonas aeruginosa: Potential for therapeutic interference with pathogenicity. ChemBioChem 2011, 12:850-853. 10.1002/cbic.201100014, 21425231.
    • (2011) ChemBioChem , vol.12 , pp. 850-853
    • Pistorius, D.1    Ullrich, A.2    Lucas, S.3    Hartmann, R.4    Kazmaier, U.5    Müller, R.6
  • 20
    • 77957967410 scopus 로고    scopus 로고
    • Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts
    • 2901523, 20406282
    • Rampioni G, Pustelny C, Fletcher M, Wright V, Bruce M, Rumbaugh K, Heeb S, Cámara M, Williams P. Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts. Environ Microbiol 2010, 12:1659-1673. 2901523, 20406282.
    • (2010) Environ Microbiol , vol.12 , pp. 1659-1673
    • Rampioni, G.1    Pustelny, C.2    Fletcher, M.3    Wright, V.4    Bruce, M.5    Rumbaugh, K.6    Heeb, S.7    Cámara, M.8    Williams, P.9
  • 21
    • 79251604303 scopus 로고    scopus 로고
    • Quinolones: from antibiotics to autoinducers
    • 10.1111/j.1574-6976.2010.00247.x, 3053476, 20738404
    • Heeb S, Fletcher M, Chhabra S, Diggle S, Williams P, Cámara M. Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev 2011, 35:247-274. 10.1111/j.1574-6976.2010.00247.x, 3053476, 20738404.
    • (2011) FEMS Microbiol Rev , vol.35 , pp. 247-274
    • Heeb, S.1    Fletcher, M.2    Chhabra, S.3    Diggle, S.4    Williams, P.5    Cámara, M.6
  • 22
    • 0035956915 scopus 로고    scopus 로고
    • QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa
    • 10.1073/pnas.051624298, 30211, 11226312
    • Chugani SA, Whiteley M, Lee KM, D'Argenio D, Manoil C, Greenberg EP. QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. PNAS 2001, 98:2752-2757. 10.1073/pnas.051624298, 30211, 11226312.
    • (2001) PNAS , vol.98 , pp. 2752-2757
    • Chugani, S.A.1    Whiteley, M.2    Lee, K.M.3    D'Argenio, D.4    Manoil, C.5    Greenberg, E.P.6
  • 23
    • 84864006267 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression
    • 10.1128/JB.06679-11, 3370851, 22505688
    • Liang H, Deng X, Ji Q, Sun F, Shen T, He C. The Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol 2012, 194:3098-3108. 10.1128/JB.06679-11, 3370851, 22505688.
    • (2012) J Bacteriol , vol.194 , pp. 3098-3108
    • Liang, H.1    Deng, X.2    Ji, Q.3    Sun, F.4    Shen, T.5    He, C.6
  • 25
    • 32644431906 scopus 로고    scopus 로고
    • Relationships between probabilistic Boolean networks and dynamic Bayesian networks as models of gene regulatory networks
    • Lähdesmäki H, Hautaniemi S, Shmulevich I, Yli-Harja O. Relationships between probabilistic Boolean networks and dynamic Bayesian networks as models of gene regulatory networks. Signal Process 2006, 86:814-834.
    • (2006) Signal Process , vol.86 , pp. 814-834
    • Lähdesmäki, H.1    Hautaniemi, S.2    Shmulevich, I.3    Yli-Harja, O.4
  • 26
    • 33845222941 scopus 로고    scopus 로고
    • Modelling and analysing genetic networks: From Boolean networks to Petri nets
    • Springer, 4210 of Lecture Notes in Computer Science
    • Steggles L, Banks R, Wipat A. Modelling and analysing genetic networks: From Boolean networks to Petri nets. Comp Meth Systems Biol 2006, 127-141. Springer, 4210 of Lecture Notes in Computer Science.
    • (2006) Comp Meth Systems Biol , pp. 127-141
    • Steggles, L.1    Banks, R.2    Wipat, A.3
  • 27
    • 84859054645 scopus 로고    scopus 로고
    • A Boolean network model of the FA/BRCA pathway
    • 10.1093/bioinformatics/bts036, 22267503
    • Rodríguez A, Sosa D, Torres L, Molina B, Frías S, Mendoza L. A Boolean network model of the FA/BRCA pathway. Bioinformatics 2012, 28:858-866. 10.1093/bioinformatics/bts036, 22267503.
    • (2012) Bioinformatics , vol.28 , pp. 858-866
    • Rodríguez, A.1    Sosa, D.2    Torres, L.3    Molina, B.4    Frías, S.5    Mendoza, L.6
  • 28
    • 0035928464 scopus 로고    scopus 로고
    • A logical analysis of the drosophila gap-gene system
    • Sanchez L, Thieffry D. A logical analysis of the drosophila gap-gene system. J Theo Biol 2001, 211:115-141.
    • (2001) J Theo Biol , vol.211 , pp. 115-141
    • Sanchez, L.1    Thieffry, D.2
  • 29
    • 72949094214 scopus 로고    scopus 로고
    • Modular logical modelling of the budding yeast cell cycle
    • 10.1039/b910101m, 19763337
    • Fauré A, Naldi A, Lopez F, Chaouiya C, Ciliberto A, Thieffry D. Modular logical modelling of the budding yeast cell cycle. Mol BioSyst 2009, 5:1787-1796. 10.1039/b910101m, 19763337.
    • (2009) Mol BioSyst , vol.5 , pp. 1787-1796
    • Fauré, A.1    Naldi, A.2    Lopez, F.3    Chaouiya, C.4    Ciliberto, A.5    Thieffry, D.6
  • 30
    • 0034968039 scopus 로고    scopus 로고
    • A mathematical model for quorum sensing in Pseudomonas aeruginosa
    • 10.1006/bulm.2000.0205, 11146885
    • Dockery J, Keener J. A mathematical model for quorum sensing in Pseudomonas aeruginosa. Bull Math Biol 2001, 63:95-116. 10.1006/bulm.2000.0205, 11146885.
    • (2001) Bull Math Biol , vol.63 , pp. 95-116
    • Dockery, J.1    Keener, J.2
  • 31
    • 77955490025 scopus 로고    scopus 로고
    • A cell-based model for quorum sensing in heterogeneous bacterial colonies
    • Melke P, Sahlin P, Levchenko A, Jönsson H. A cell-based model for quorum sensing in heterogeneous bacterial colonies. PLoS Comp Biol 2010, 6:e1000819.
    • (2010) PLoS Comp Biol , vol.6
    • Melke, P.1    Sahlin, P.2    Levchenko, A.3    Jönsson, H.4
  • 33
    • 7444244983 scopus 로고    scopus 로고
    • Mathematical modelling of therapies targeted at bacterial quorum sensing
    • 10.1016/j.mbs.2004.06.008, 15494175
    • Anguige K, King J, Ward J, Williams P. Mathematical modelling of therapies targeted at bacterial quorum sensing. Math Biosci 2004, 192:39-83. 10.1016/j.mbs.2004.06.008, 15494175.
    • (2004) Math Biosci , vol.192 , pp. 39-83
    • Anguige, K.1    King, J.2    Ward, J.3    Williams, P.4
  • 34
    • 0036951064 scopus 로고    scopus 로고
    • A mathematical model of quorum sensing in a growing bacterial biofilm
    • Chopp D, Kirisits M, Moran B, Parsek M. A mathematical model of quorum sensing in a growing bacterial biofilm. J Ind Microbiol Biotech 2002, 29:339-346.
    • (2002) J Ind Microbiol Biotech , vol.29 , pp. 339-346
    • Chopp, D.1    Kirisits, M.2    Moran, B.3    Parsek, M.4
  • 35
    • 84863442912 scopus 로고    scopus 로고
    • Inhibition of quorum sensing in a computational biofilm simulation
    • 10.1016/j.biosystems.2012.02.002, 22374433
    • Fozard J, Lees M, King J, Logan B. Inhibition of quorum sensing in a computational biofilm simulation. Biosystems 2012, 109:105-114. 10.1016/j.biosystems.2012.02.002, 22374433.
    • (2012) Biosystems , vol.109 , pp. 105-114
    • Fozard, J.1    Lees, M.2    King, J.3    Logan, B.4
  • 36
    • 0025755803 scopus 로고
    • Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression
    • 207884, 1902216
    • Gambello M, Iglewski B. Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression. J Bacteriol 1991, 173:3000-3009. 207884, 1902216.
    • (1991) J Bacteriol , vol.173 , pp. 3000-3009
    • Gambello, M.1    Iglewski, B.2
  • 37
    • 79960558506 scopus 로고    scopus 로고
    • Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems
    • 10.1038/ismej.2011.13, 3146268, 21368905
    • Wilder C, Diggle S, Schuster M. Cooperation and cheating in Pseudomonas aeruginosa: the roles of the las, rhl and pqs quorum-sensing systems. ISME J 2011, 5:1332-1343. 10.1038/ismej.2011.13, 3146268, 21368905.
    • (2011) ISME J , vol.5 , pp. 1332-1343
    • Wilder, C.1    Diggle, S.2    Schuster, M.3
  • 38
    • 80052314915 scopus 로고    scopus 로고
    • A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes
    • 10.1371/journal.ppat.1002192, 3150319, 21829370
    • Kesarwani M, Hazan R, He J, Que Y, Apidianakis Y, Lesic B, Xiao G, Dekimpe V, Milot S, Deziel E, et al. A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes. PLoS Pathog 2011, 7:e1002192. 10.1371/journal.ppat.1002192, 3150319, 21829370.
    • (2011) PLoS Pathog , vol.7
    • Kesarwani, M.1    Hazan, R.2    He, J.3    Que, Y.4    Apidianakis, Y.5    Lesic, B.6    Xiao, G.7    Dekimpe, V.8    Milot, S.9    Deziel, E.10
  • 39
    • 0036889038 scopus 로고    scopus 로고
    • Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa
    • 10.1128/JB.184.23.6472-6480.2002, 135424, 12426334
    • Gallagher L, McKnight S, Kuznetsova M, Pesci E, Manoil C. Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa. J Bacteriol 2002, 184:6472-6480. 10.1128/JB.184.23.6472-6480.2002, 135424, 12426334.
    • (2002) J Bacteriol , vol.184 , pp. 6472-6480
    • Gallagher, L.1    McKnight, S.2    Kuznetsova, M.3    Pesci, E.4    Manoil, C.5
  • 40
    • 55749096264 scopus 로고    scopus 로고
    • PqsE functions independently of PqsR-Pseudomonas quinolone signal and enhances the rhl quorum-sensing system
    • 10.1128/JB.00753-08, 2580708, 18776012
    • Farrow III J, Sund Z, Ellison M, Wade D, Coleman J, Pesci E. PqsE functions independently of PqsR-Pseudomonas quinolone signal and enhances the rhl quorum-sensing system. J Bacteriol 2008, 190:7043-7051. 10.1128/JB.00753-08, 2580708, 18776012.
    • (2008) J Bacteriol , vol.190 , pp. 7043-7051
    • Farrow III, J.1    Sund, Z.2    Ellison, M.3    Wade, D.4    Coleman, J.5    Pesci, E.6
  • 42
    • 84868112328 scopus 로고    scopus 로고
    • Identification of small-molecule antagonists of the Pseudomonas aeruginosa transcriptional regulator PqsR: Biophysically guided hit discovery and optimization
    • 10.1021/cb300208g, 22765028
    • Klein T, Henn C, de J, Zimmer C, Kirsch B, Maurer C, Pistorius D, Müller R, Steinbach A, Hartmann R. Identification of small-molecule antagonists of the Pseudomonas aeruginosa transcriptional regulator PqsR: Biophysically guided hit discovery and optimization. ACS Chem Biol 2012, 7:1496-1501. 10.1021/cb300208g, 22765028.
    • (2012) ACS Chem Biol , vol.7 , pp. 1496-1501
    • Klein, T.1    Henn, C.2    de, J.3    Zimmer, C.4    Kirsch, B.5    Maurer, C.6    Pistorius, D.7    Müller, R.8    Steinbach, A.9    Hartmann, R.10
  • 43
    • 84858987560 scopus 로고    scopus 로고
    • Discovery of antagonists of PqsR, a key player in 2-Alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa
    • 10.1016/j.chembiol.2012.01.015, 22444593
    • Lu C, Kirsch B, Zimmer C, de Jong J, Henn C, Maurer C, Müsken M, Steinbach A, Hartmann R. Discovery of antagonists of PqsR, a key player in 2-Alkyl-4-quinolone-dependent quorum sensing in Pseudomonas aeruginosa. Chem Biol 2012, 19:381-390. 10.1016/j.chembiol.2012.01.015, 22444593.
    • (2012) Chem Biol , vol.19 , pp. 381-390
    • Lu, C.1    Kirsch, B.2    Zimmer, C.3    de Jong, J.4    Henn, C.5    Maurer, C.6    Müsken, M.7    Steinbach, A.8    Hartmann, R.9
  • 44
    • 70350495852 scopus 로고    scopus 로고
    • Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein
    • Yu S, Jensen V, Seeliger J, Feldmann I, Weber S, Schleicher E, Häussler S, Blankenfeldt W. Structure elucidation and preliminary assessment of hydrolase activity of PqsE, the Pseudomonas quinolone signal (PQS) response protein. Biochem 2009, 48:10298-10307.
    • (2009) Biochem , vol.48 , pp. 10298-10307
    • Yu, S.1    Jensen, V.2    Seeliger, J.3    Feldmann, I.4    Weber, S.5    Schleicher, E.6    Häussler, S.7    Blankenfeldt, W.8
  • 45
    • 70350462737 scopus 로고    scopus 로고
    • The multifaceted proteins MvaT and MvaU, members of the H-NS family, control arginine metabolism, pyocyanin synthesis, and prophage activation in Pseudomonas aeruginosa PAO1
    • 10.1128/JB.00888-09, 2753020, 19684136
    • Li C, Wally H, Miller S, Lu C. The multifaceted proteins MvaT and MvaU, members of the H-NS family, control arginine metabolism, pyocyanin synthesis, and prophage activation in Pseudomonas aeruginosa PAO1. J Bacteriol 2009, 191:6211-6218. 10.1128/JB.00888-09, 2753020, 19684136.
    • (2009) J Bacteriol , vol.191 , pp. 6211-6218
    • Li, C.1    Wally, H.2    Miller, S.3    Lu, C.4
  • 46
    • 0035685204 scopus 로고    scopus 로고
    • Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1
    • 10.1128/JB.183.21.6454-6465.2001, 100142, 11591691
    • Mavrodi D, Bonsall R, Delaney S, Soule M, Phillips G, Thomashow L. Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1. J Bacteriol 2001, 183:6454-6465. 10.1128/JB.183.21.6454-6465.2001, 100142, 11591691.
    • (2001) J Bacteriol , vol.183 , pp. 6454-6465
    • Mavrodi, D.1    Bonsall, R.2    Delaney, S.3    Soule, M.4    Phillips, G.5    Thomashow, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.