Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 5, 2012, Pages 2314-2325

  Jakobsen, Tim Holm ^a   Van Gennip, Maria ^a   Phipps, Richard Kerry ^b   Shanmugham, Meenakshi Sundaram ^b   Christensen, Louise Dahl ^a   Alhede, Morten ^a   Skindersoe, Mette Eline ^c   Rasmussen, Thomas Bovbjerg ^d   Friedrich, Karlheinz ^e   Uthe, Friedrich ^e   Jensen, Peter Østrup ^f   Moser, Claus ^f   Nielsen, Kristian Fog ^b   Eberl, Leo ^g   Larsen, Thomas Ostenfeld ^b   Tanner, David ^b   Høiby, Niels ^a,f   Bjarnsholt, Thomas ^a,f   Givskov, Michael ^a,h  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

^d Department of Physiology ^*  (Denmark)

^e JENA UNIVERSITY HOSPITAL   (Germany)

^f Rigshospitalet   (Denmark)

^g UNIVERSITY OF ZURICH   (Switzerland)

^h NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AJOENE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; RHAMNOLIPID; TETRANDRINE; TOBRAMYCIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL LOAD; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA MICROARRAY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG ISOLATION; DRUG POTENTIATION; DRUG PURIFICATION; DRUG SPECIFICITY; DRUG STABILITY; FEMALE; FRACTIONATION; GARLIC; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LUNG INFECTION; MALE; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CHEMICAL FRACTIONATION; DISULFIDES; DRUG SYNERGISM; GARLIC; GENE EXPRESSION REGULATION, BACTERIAL; GENES, REPORTER; GLYCOLIPIDS; MICE; NEUTROPHILS; PLANT EXTRACTS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; QUORUM SENSING; RESPIRATORY TRACT INFECTIONS; TOBRAMYCIN; VIRULENCE FACTORS;

EID: 84860202961     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.05919-11     Document Type: Article

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