Genetically programmable pathogen sense and destroy

ACS Synthetic Biology

Volumn 2, Issue 12, 2013, Pages 715-723

  Gupta, Saurabh ^a   Bram, Eran E ^a   Weiss, Ron ^a  

^a USA   (United States)

Author keywords

bacteria; bacteriocin; chimeric proteins; colcin; FlgM; pyocin

Indexed keywords

BACTERIOCIN; CARRIER PROTEIN; COLICIN E3; COPY PROTEIN; FLGM PROTEIN; PYOCIN; PYOCIN S3; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; FLGM PROTEIN, BACTERIA; HYBRID PROTEIN;

ARTICLE; BACTERIAL FLAGELLUM; BACTERIAL GROWTH; BACTERIAL SECRETION SYSTEM; BACTERIAL STRAIN; BIOENGINEERING; CONTROLLED STUDY; ESCHERICHIA COLI; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; WILD TYPE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; PROCEDURES; SYNTHETIC BIOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIOCINS; CELL PROLIFERATION; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; RECOMBINANT FUSION PROTEINS; SYNTHETIC BIOLOGY;

EID: 84889018656     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb4000417     Document Type: Article

References (39)

1. Finch, R. G. (2004) Antibiotic resistance: a view from the prescriber Nat. Rev. Microbiol. 2, 989-994
2. Na, X. and Kelly, C. (2011) Probiotics in clostridium difficile Infection J. Clin. Gastroenterol. 45 (Suppl) S154-158
3. Gough, E., Shaikh, H., and Manges, A. R. (2011) Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection Clin. Infect. Dis. 53, 994-1002
4. Cotter, P. D., Hill, C., and Ross, R. P. (2005) Bacteriocins: developing innate immunity for food Nat. Rev. Microbiol. 3, 777-788
5. Parret, A. H. and De Mot, R. (2002) Bacteria killing their own kind: novel bacteriocins of Pseudomonas and other gamma-proteobacteria Trends Microbio.l 10, 107-112
6. Cascales, E. 2007, Colicin biology Microbiol. Mol. Biol. Rev. 71, 158-229
7. Kageyama, M., Kobayashi, M., Sano, Y., and Masaki, H. (1996) Construction and characterization of pyocin-colicin chimeric proteins J. Bacteriol. 178, 103-110
8. Mergulhao, F. J., Summers, D. K., and Monteiro, G. A. (2005) Recombinant protein secretion in Escherichia coli Biotechnol. Adv. 23, 177-202
9. Saier, M. H., Jr. (2006) Protein secretion and membrane insertion systems in gram-negative bacteria J. Membr. Biol. 214, 75-90
10. Sandkvist, M. and Bagdasarian, M. (1996) Secretion of recombinant proteins by Gram-negative bacteria Curr. Opin. Biotechnol. 7, 505-511
11. Wickner, W. and Schekman, R. (2005) Protein translocation across biological membranes Science 310, 1452-1456
12. Sorensen, H. P. and Mortensen, K. K. (2005) Advanced genetic strategies for recombinant protein expression in Escherichia coli J. Biotechnol. 115, 113-128
13. Filloux, A., Hachani, A., and Bleves, S. (2008) The bacterial type VI secretion machine: yet another player for protein transport across membranes Microbiology 154, 1570-1583
14. Georgiou, G. and Segatori, L. (2005) Preparative expression of secreted proteins in bacteria: status report and future prospects Curr. Opin. Biotechnol. 16, 538-545
15. San Miguel, M., Marrington, R., Rodger, P. M., Rodger, A., and Robinson, C. (2003) An Escherichia coli twin-arginine signal peptide switches between helical and unstructured conformations depending on the hydrophobicity of the environment Eur. J. Biochem. 270, 3345-3352
16. Bernard, C. S., Brunet, Y. R., Gueguen, E., and Cascales, E. (2010) Nooks and crannies in type VI secretion regulation J. Bacteriol. 192, 3850-3860
17. Bingle, L. E., Bailey, C. M., and Pallen, M. J. (2008) Type VI secretion: a beginner's guide Curr. Opin. Microbiol. 11, 3-8
18. Feltcher, M. E., Sullivan, J. T., and Braunstein, M. (2010) Protein export systems of Mycobacterium tuberculosis: novel targets for drug development? Future Microbiol. 5, 1581-1597
19. Delepelaire, P. (2004) Type I secretion in gram-negative bacteria Biochim. Biophys. Acta 1694, 149-161
20. Aldridge, P., Gnerer, J., Karlinsey, J. E., and Hughes, K. T. (2006) Transcriptional and translational control of the Salmonella fliC gene J. Bacteriol. 188, 4487-4496
21. Chilcott, G. S. and Hughes, K. T. (2000) Coupling of flagellar gene expression to flagellar assembly in Salmonella enterica serovar typhimurium and Escherichia coli Microbiol. Mol. Biol. Rev. 64, 694-708
22. Karlinsey, J. E. 2000, Completion of the hook-basal body complex of the Salmonella typhimurium flagellum is coupled to FlgM secretion and fliC transcription Mol. Microbiol. 37, 1220-1231
23. Zwietering, M. H., Jongenburger, I., Rombouts, F. M., and van 't Riet, K. (1990) Modeling of the bacterial growth curve Appl. Environ. Microbiol. 56, 1875-1881
24. Gupta, P. and Lee, K. H. (2008) Silent mutations result in HlyA hypersecretion by reducing intracellular HlyA protein aggregates Biotechnol. Bioeng. 101, 967-974
25. Collins, C. H., Arnold, F. H., and Leadbetter, J. R. (2005) Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl-homoserine lactones Mol. Microbiol. 55, 712-723
26. Aldridge, P. D. 2006, The flagellar-specific transcription factor, sigma28, is the Type III secretion chaperone for the flagellar-specific anti-sigma28 factor FlgM Genes Dev. 20, 2315-2326
27. Chadsey, M. S. and Hughes, K. T. (2001) A multipartite interaction between Salmonella transcription factor sigma28 and its anti-sigma factor FlgM: implications for sigma28 holoenzyme destabilization through stepwise binding J. Mol. Biol. 306, 915-929
28. Chevance, F. F., Karlinsey, J. E., Wozniak, C. E., and Hughes, K. T. (2006) A little gene with big effects: a serT mutant is defective in flgM gene translation J. Bacteriol. 188, 297-304
29. Daughdrill, G. W., Hanely, L. J., and Dahlquist, F. W. (1998) The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformations Biochemistry 37, 1076-1082
30. Frisk, A., Jyot, J., Arora, S. K., and Ramphal, R. (2002) Identification and functional characterization of flgM, a gene encoding the anti-sigma 28 factor in Pseudomonas aeruginosa J. Bacteriol. 184, 1514-1521
31. Hughes, K. T., Gillen, K. L., Semon, M. J., and Karlinsey, J. E. (1993) Sensing structural intermediates in bacterial flagellar assembly by export of a negative regulator Science 262, 1277-1280
32. Schmitt, C. K., Darnell, S. C., and O'Brien, A. D. (1996) The attenuated phenotype of a Salmonella typhimurium flgM mutant is related to expression of FliC flagellin J. Bacteriol. 178, 2911-2915
33. Schmitt, C. K., Darnell, S. C., Tesh, V. L., Stocker, B. A., and O'Brien, A. D. (1994) Mutation of flgM attenuates virulence of Salmonella typhimurium, and mutation of fliA represses the attenuated phenotype J. Bacteriol. 176, 368-377
34. Yokoseki, T., Iino, T., and Kutsukake, K. (1996) Negative regulation by fliD, fliS, and fliT of the export of the flagellum-specific anti-sigma factor, FlgM, in Salmonella typhimurium J. Bacteriol. 178, 899-901
35. Kim, J., Hegde, M., and Jayaraman, A. (2010) Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions Lab Chip 10, 43-50
36. Saeidi, N. 2011, Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen Mol. Syst. Biol. 7, 521
37. Michel-Briand, Y. and Baysse, C. (2002) The pyocins of Pseudomonas aeruginosa Biochimie 84, 499-510
38. Gasteiger, E. 2003, ExPASy: The proteomics server for in-depth protein knowledge and analysis Nucleic Acids Res. 31, 3784-3788
39. Schneider, C. A., Rasband, W. S., and Eliceiri, K. W. (2012) NIH Image to ImageJ: 25 years of image analysis Nat. Methods 9, 671-675