Linking peroxiredoxin and vacuolar-ATPase functions in calorie restriction-mediated life span extension

International Journal of Cell Biology

Volumn , Issue , 2014, Pages

  Molin, Mikael ^a   Demir, Ayse Banu ^a,b,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b IZMIR INSTITUTE OF TECHNOLOGY   (Turkey)

^c DOKUZ EYLUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; FREE RADICAL; GLUCOSE; HYDROGEN PEROXIDE; IRON; PEROXIDE; PEROXIREDOXIN; REACTIVE OXYGEN METABOLITE;

ACIDIFICATION; AGING; CALORIC RESTRICTION; CELL PH; HUMAN; IRON METABOLISM; LIFE EXTENSION; NONHUMAN; NUTRITION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; STRESS;

EID: 84896880111     PISSN: 16878876     EISSN: 16878884     Source Type: Journal    
DOI: 10.1155/2014/913071     Document Type: Review

References (122)

1. Kaeberlein M., Lessons on longevity from budding yeast. Nature 2010 464 7288 513 519 2-s2.0-77950214581 10.1038/nature08981
2. Kenyon C., A pathway that links reproductive status to lifespan in Caenorhabditis elegans. Annals of the New York Academy of Sciences 2010 1204 156 162 2-s2.0-77956244148 10.1111/j.1749-6632.2010.05640.x
3. McDonald R. B., Ramsey J. J., Honoring Clive McCay and 75 years of calorie restriction research. Journal of Nutrition 2010 140 7 1205 1210 2-s2.0-77953790156 10.3945/jn.110.122804
4. Lin S.-J., Defossez P.-A., Guarente L., Requirement of NAD and SIR2 for life-span extension by calorie restriction in saccharomyces cerevisiae. Science 2000 289 5487 2126 2128 2-s2.0-0034703217 10.1126/science.289.5487.2126
5. Jiang J. C., Jaruga E., Repnevskaya M. V., Jazwinski S. M., An intervention resembling caloric restriction prolongs life span and retards aging in yeast. FASEB Journal 2000 14 14 2135 2137 2-s2.0-0033738362
6. Cohen H. Y., Miller C., Bitterman K. J., Wall N. R., Hekking B., Kessler B., Howitz K. T., Gorospe M., De Cabo R., Sinclair D. A., Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 2004 305 5682 390 392 2-s2.0-3142740860 10.1126/science.1099196
7. Kaeberlein M., Kirkland K. T., Fields S., Kennedy B. K., Sir2-independent life span extension by calorie restriction in yeast. PLoS Biology 2004 2 9, e296 2-s2.0-19344374925 10.1371/journal.pbio.0020296
8. Fontana L., Partridge L., Longo V. D., Extending healthy life span-from yeast to humans. Science 2010 328 5976 321 326 2-s2.0-77951176737 10.1126/science.1172539
9. Enns L. C., Morton J. F., Treuting P. R., Emond M. J., Wolf N. S., McKnight G. S., Rabinovitch P. S., Ladiges W. C., Disruption of protein kinase A in mice enhances healthy aging. PLoS ONE 2009 4 6 2-s2.0-67650149336 10.1371/journal.pone.0005963 e5963
10. Zaman S., Lippman S. I., Zhao X., Broach J. R., How Saccharomyces responds to nutrients. Annual Review of Genetics 2008 42 27 81 2-s2.0-58549084410 10.1146/annurev.genet.41.110306.130206
11. Hughes A. L., Gottschling D. E., An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature 2012 492 7428 261 265
12. 2 resistance elicited by caloric restriction require the peroxiredoxin Tsa1 in Saccharomyces cerevisiae. Molecular Cell 2011 43 5 823 833 2-s2.0-80052217019 10.1016/j.molcel.2011.07.027
13. Bonfils G., Jaquenoud M., Bontron S., Ostrowicz C., Ungermann C., De Virgilio C., Leucyl-tRNA synthetase controls TORC1 via the EGO complex. Molecular Cell 2012 46 1 105 110 2-s2.0-84859704385 10.1016/j.molcel.2012.02.009
14. Dechant R., Binda M., Lee S. S., Pelet S., Winderickx J., Peter M., Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase. EMBO Journal 2010 29 15 2515 2526 2-s2.0-77955405903 10.1038/emboj.2010.138
15. Zoncu R., Bar-Peled L., Efeyan A., Wang S., Sancak Y., Sabatini D. M., mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H+-ATPase. Science 2011 334 6056 678 683 2-s2.0-80555143078 10.1126/science.1207056
16. Orij R., Urbanus M. L., Vizeacoumar F. J., Giaever G., Boone C., Nislow C., Brul S., Smits G. J., Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae. Genome Biology 2012 13 9, article R80
17. D'Autréaux B., Toledano M. B., ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nature Reviews Molecular Cell Biology 2007 8 10 813 824 2-s2.0-34648813720 10.1038/nrm2256
18. Stadtman E. R., Protein oxidation and aging. Science 1992 257 5074 1220 1224 2-s2.0-0026795635
19. Harman D., The free radical theory of aging. Antioxidants and Redox Signaling 2003 5 5 557 561 2-s2.0-0142213542
20. Erjavec N., Nyström T., Sir2p-dependent protein segregation gives rise to a superior reactive oxygen species management in the progeny of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America 2007 104 26 10877 10881 2-s2.0-34547410267 10.1073/pnas.0701634104
21. Laun P., Pichova A., Madeo F., Fuchs J., Ellinger A., Kohlwein S., Dawes I., Fröhlich K.-U., Breitenbach M., Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis. Molecular Microbiology 2001 39 5 1166 1173 2-s2.0-0035100306 10.1046/j.1365-2958.2001. 02317.x
22. Andres-Mateos E., Perier C., Zhang L., Blanchard-Fillion B., Greco T. M., Thomas B., Han S. K., Sasaki M., Ischiropoulos H., Przedborski S., Dawson T. M., Dawson V. L., DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proceedings of the National Academy of Sciences of the United States of America 2007 104 37 14807 14812 2-s2.0-35548972027 10.1073/pnas.0703219104
23. Asha Devi S., Sagar Chandrasekar B. K., Manjula K. R., Ishii N., Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats. Experimental Gerontology 2011 46 11 958 964 2-s2.0-80054862809 10.1016/j.exger.2011.08.006
24. Pratico D., Lipid peroxidation and the aging process. Science of Aging Knowledge Environment 2002 2002 50, article re5
25. Carrard G., Bulteau A.-L., Petropoulos I., Friguet B., Impairment of proteasome structure and function in aging. International Journal of Biochemistry and Cell Biology 2002 34 11 1461 1474 2-s2.0-0036830343 10.1016/S1357-2725(02)00085-7
26. Demir A. B., Koc A., Assessment of chronological lifespan dependent molecular damages in yeast lacking mitochondrial antioxidant genes. Biochemical and Biophysical Research Communications 2010 400 1 106 110 2-s2.0-79953024462 10.1016/j.bbrc.2010.08.019
27. Yan L.-J., Levine R. L., Sohal R. S., Oxidative damage during aging targets mitochondrial aconitase. Proceedings of the National Academy of Sciences of the United States of America 1997 94 21 11168 11172 2-s2.0-0030881686 10.1073/pnas.94.21.11168
28. Sohal R. S., Kua H.-H., Agarwal S., Forster M. J., Lal H., Oxidative damage, mitochondrial oxidant generation and antioxidant defenses: during aging and in response to food restriction in the mouse. Mechanisms of Ageing and Development 1994 74 1-2 121 133 2-s2.0-0028342438 10.1016/0047-6374(94)90104-X
29. Sohal R. S., Weindruch R., Oxidative stress, caloric restriction, and aging. Science 1996 273 5271 59 63 2-s2.0-0030038103
30. Fontán-Lozano A., López-Lluch G., Delgado-García J. M., Navas P., Carrión A. M., Molecular bases of caloric restriction regulation of neuronal synaptic plasticity. Molecular Neurobiology 2008 38 2 167 177 2-s2.0-58149157465 10.1007/s12035-008-8040-1
31. Hsu C.-P., Odewale I., Alcendor R. R., Sadoshima J., Sirt1 protects the heart from aging and stress. Biological Chemistry 2008 389 3 221 231 2-s2.0-40149092156 10.1515/BC.2008.032
32. Levine R. L., Carbonyl modified proteins in cellular regulation, aging, and disease. Free Radical Biology and Medicine 2002 32 9 790 796 2-s2.0-0036569401 10.1016/S0891-5849(02)00765-7
33. Sohal R. S., Agarwal S., Candas M., Forster M. J., Lal H., Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice. Mechanisms of Ageing and Development 1994 76 2-3 215 224 2-s2.0-0028116159 10.1016/0047-6374(94)91595-4
34. Finkel T., Holbrook N. J., Oxidants, oxidative stress and the biology of ageing. Nature 2000 408 6809 239 247 2-s2.0-0034626735 10.1038/35041687
35. Gianni D., DerMardirossian C., Bokoch G. M., Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation. European Journal of Cell Biology 2011 90 2-3 164 171 2-s2.0-79151477025 10.1016/j.ejcb.2010.05.007
36. Molin M., Renault J.-P., Lagniel G., Pin S., Toledano M., Labarre J., Ionizing radiation induces a Yap1-dependent peroxide stress response in yeast. Free Radical Biology and Medicine 2007 43 1 136 144 2-s2.0-34250011458 10.1016/j.freeradbiomed.2007.04.007
37. Bienert G. P., Møller A. L. B., Kristiansen K. A., Schulz A., Møller I. M., Schjoerring J. K., Jahn T. P., Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes. Journal of Biological Chemistry 2007 282 2 1183 1192 2-s2.0-33847753534 10.1074/jbc.M603761200
38. Labunskyy V. M., Gladyshev V. N., Role of reactive oxygen species-mediated signaling in aging. Antioxidants & Redox Signaling 2013 19 12 1362 1372
39. Ristow M., Schmeisser S., Extending life span by increasing oxidative stress. Free Radical Biology and Medicine 2011 51 2 327 336 2-s2.0-79959350253 10.1016/j.freeradbiomed.2011.05.010
40. Fomenko D. E., Koc A., Agisheva N., Jacobsen M., Kaya A., Malinouski M., Rutherford J. C., Siu K.-L., Jin D.-Y., Winge D. R., Gladyshev V. N., Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide. Proceedings of the National Academy of Sciences of the United States of America 2011 108 7 2729 2734 2-s2.0-79952582563 10.1073/pnas.1010721108
41. Conway J. P., Kinter M., Dual role of peroxiredoxin I in macrophage-derived foam cells. Journal of Biological Chemistry 2006 281 38 27991 28001 2-s2.0-33748775173 10.1074/jbc.M605026200
42. Oláhová M., Taylor S. R., Khazaipoul S., Wang J., Morgan B. A., Matsumoto K., Blackwell T. K., Veal E. A., A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance. Proceedings of the National Academy of Sciences of the United States of America 2008 105 50 19839 19844 2-s2.0-58149395029 10.1073/pnas.0805507105
43. 2 mediates endoplasmic reticulum signaling through local ras activation. Molecular and Cellular Biology 2010 30 14 3553 3568 2-s2.0-77954382142 10.1128/MCB.01445-09
44. Van Raamsdonk J. M., Hekimi S., Superoxide dismutase is dispensable for normal animal lifespan. Proceedings of the National Academy of Sciences of the United States of America 2012 109 15 5785 5790 2-s2.0-84859575436 10.1073/pnas.1116158109
45. Lin S.-J., Kaeberlein M., Andalis A. A., Sturtz L. A., Defossez P.-A., Culotta V. C., Fink G. R., Guarente L., Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 2002 418 6895 344 348 2-s2.0-0037130175 10.1038/nature00829
46. Schleit J., Johnson S. C., Bennett C. F., Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell 2013 12 6 1050 1061
47. Nisoli E., Tonello C., Cardile A., Cozzi V., Bracale R., Tedesco L., Falcone S., Valerio A., Cantoni O., Clementi E., Moncada S., Carruba M. O., Cell biology: calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005 310 5746 314 317 2-s2.0-26844558334 10.1126/science.1117728
48. Schulz T. J., Zarse K., Voigt A., Urban N., Birringer M., Ristow M., Glucose restriction extends caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metabolism 2007 6 4 280 293 2-s2.0-34748850786 10.1016/j.cmet.2007.08.011
49. Chang T.-S., Jeong W., Hyun A. W., Sun M. L., Park S., Sue G. R., Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine. Journal of Biological Chemistry 2004 279 49 50994 51001 2-s2.0-10944237769 10.1074/jbc.M409482200
50. 2 mixed-function oxidation system. Journal of Biological Chemistry 1988 263 10 4704 4711 2-s2.0-0023929362
51. Storz G., Jacobson F. S., Tartaglia L. A., Morgan R. W., Silveira L. A., Ames B. N., An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp. Journal of Bacteriology 1989 171 4 2049 2055 2-s2.0-0024604234
52. Hyun A. W., Jeong W., Chang T.-S., Kwang J. P., Sung J. P., Jeong S. Y., Sue G. R., Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-Cys peroxiredoxins. Journal of Biological Chemistry 2005 280 5 3125 3128 2-s2.0-13544272571 10.1074/jbc.C400496200
53. Hall A., Karplus P. A., Poole L. B., Typical 2-Cys peroxiredoxins- structures, mechanisms and functions. FEBS Journal 2009 276 9 2469 2477 2-s2.0-64149085448 10.1111/j.1742-4658.2009.06985.x
54. Biteau B., Labarre J., Toledano M. B., ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin. Nature 2003 425 6961 980 984 2-s2.0-0242416188 10.1038/nature02075
55. Lee K.-S., Iijima-Ando K., Iijima K., Lee W.-J., Lee J. H., Yu K., Lee D.-S., JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span. Journal of Biological Chemistry 2009 284 43 29454 29461 2-s2.0-70350398226 10.1074/jbc.M109.028027
56. Neumann C. A., Krause D. S., Carman C. V., Das S., Dubey D. P., Abraham J. L., Bronson R. T., Fujiwara Y., Orkin S. H., Van Etten R. A., Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression. Nature 2003 424 6948 561 565 2-s2.0-0042568938 10.1038/nature01819
57. Timmermann B., Jarolim S., Russmayer H., Kerick M., Michel S., Krüger A., Bluemlein K., Laun P., Grillari J., Lehrach H., Breitenbach M., Ralser M., A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging. Aging 2010 2 8 475 486 2-s2.0-79952197002
58. Nystrom T., Yang J., Molin M., Peroxiredoxins, gerontogenes linking aging to genome instability and cancer. Genes & Development 2012 26 18 2001 2008
59. Huang M.-E., Kolodner R. D., A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. Molecular Cell 2005 17 5 709 720 2-s2.0-14644425402 10.1016/j.molcel.2005.02.008
60. Ragu S., Faye G., Iraqui I., Masurel-Heneman A., Kolodner R. D., Huang M.-E., Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death. Proceedings of the National Academy of Sciences of the United States of America 2007 104 23 9747 9752 2-s2.0-34547459934 10.1073/pnas.0703192104
61. 2 receptor and redox-transducer in gene activation. Cell 2002 111 4 471 481 2-s2.0-0037110454 10.1016/S0092-8674(02)01048-6
62. Tachibana T., Okazaki S., Murayama A., Naganuma A., Nomoto A., Kuge S., A major peroxiredoxin-induced activation of yap 1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation. Journal of Biological Chemistry 2009 284 7 4464 4472 2-s2.0-63249111293 10.1074/jbc.M807583200
63. Wong C.-M., Siu K.-L., Jin D.-Y., Peroxiredoxin-null yeast cells are hypersensitive to oxidative stress and are genomically unstable. Journal of Biological Chemistry 2004 279 22 23207 23213 2-s2.0-2542504409 10.1074/jbc.M402095200
64. Lin V. S., Dickinson B. C., Chang C. J., Boronate-based fluorescent probes: imaging hydrogen peroxide in living systems. Methods in Enzymology 2013 526 19 43
65. Lukyanov K. A., Belousov V. V., Genetically encoded fluorescent redox sensors. Biochim Biophys Acta 2014 1840 2 745 756
66. Sue G. R., Ho Z. C., Kim K., Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radical Biology and Medicine 2005 38 12 1543 1552 2-s2.0-19444375216 10.1016/j.freeradbiomed.2005.02.026
67. 2 scavenging and signaling. Antioxidants and Redox Signaling 2008 10 9 1565 1575 2-s2.0-46449133872 10.1089/ars.2008.2049
68. Ghaemmaghami S., Huh W.-K., Bower K., Howson R. W., Belle A., Dephoure N., O'Shea E. K., Weissman J. S., Global analysis of protein expression in yeast. Nature 2003 425 6959 737 741 2-s2.0-0142215475 10.1038/nature02046
69. Iraqui I., Kienda G., Soeur J., Faye G., Baldacci G., Kolodner R. D., Huang M.-E., Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae. PLoS Genetics 2009 5 6, article e1000524 2-s2.0-67651202633 10.1371/journal.pgen. 1000524
70. Wong C.-M., Zhou Y., Ng R. W. M., Kung H.-F., Jin D.-Y., Cooperation of yeast peroxiredoxins Tsa1p and Tsa2p in the cellular defense against oxidative and nitrosative stress. Journal of Biological Chemistry 2002 277 7 5385 5394 2-s2.0-0037085384 10.1074/jbc.M106846200
71. Cao J., Schulte J., Knight A., Leslie N. R., Zagozdzon A., Bronson R., Manevich Y., Beeson C., Neumann C. A., Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO Journal 2009 28 10 1505 1517 2-s2.0-67349147914 10.1038/emboj.2009.101
72. Neumann C. A., Cao J., Manevich Y., Peroxiredoxin 1 and its role in cell signaling. Cell Cycle 2009 8 24 4072 4078 2-s2.0-74849098583
73. Hall A., Nelson K., Poole L. B., Karplus P. A., Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins. Antioxidants and Redox Signaling 2011 15 3 795 815 2-s2.0-79958059617 10.1089/ars.2010.3624
74. Saccoccia F., Di Micco P., Boumis G., Brunori M., Koutris I., Miele A. E., Morea V., Sriratana P., Williams D. L., Bellelli A., Angelucci F., Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Structure 2012 20 3 429 439 2-s2.0-84857977832 10.1016/j.str.2012.01.004
75. 2 and protein chaperones. Antioxidants and Redox Signaling 2011 15 3 781 794 2-s2.0-79951643450 10.1089/ars.2010.3393
76. Jang H. H., Lee K. O., Chi Y. H., Jung B. G., Park S. K., Park J. H., Lee J. R., Lee S. S., Moon J. C., Yun J. W., Choi Y. O., Kim W. Y., Kang J. S., Cheong G.-W., Yun D.-J., Rhee S. G., Cho M. J., Lee S. Y., Two enzymes in one: two yeast peroxiredoxins display oxidative stress-dependent switching from a peroxidase to a molecular chaperone function. Cell 2004 117 5 625 635 2-s2.0-2542464938 10.1016/j.cell.2004.05.002
77. Musicco C., Capelli V., Pesce V., Timperio A. M., Calvani M., Mosconi L., Zolla L., Cantatore P., Gadaleta M. N., Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria. Biochimica et Biophysica Acta 2009 1787 7 890 896 2-s2.0-67649268322 10.1016/j.bbabio.2009.03.002
78. Choi M. H., Lee I. K., Kim G. W., Kim B. U., Han Y.-H., Yu D.-Y., Park H. S., Kim K. Y., Lee J. S., Choi C., Bae Y. S., Lee B. I., Rhee S. G., Kang S. W., Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature 2005 435 7040 347 353 2-s2.0-19644394554 10.1038/nature03587
79. Bishop N. A., Guarente L., Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nature Reviews Genetics 2007 8 11 835 844 2-s2.0-35348972430 10.1038/nrg2188
80. Kaeberlein M., Powers R. W. III, Steffen K. K., Westman E. A., Hu D., Dang N., Kerr E. O., Kirkland K. T., Fields S., Kennedy B. K., Cell biology: regulation of yeast replicative life span by TOR and Sch9 response to nutrients. Science 2005 310 5751 1193 1196 2-s2.0-27744511769 10.1126/science.1115535
81. Enns L. C., Morton J. F., Mangalindan R. S., McKnight G. S., Schwartz M. W., Kaeberlein M. R., Kennedy B. K., Rabinovitch P. S., Ladiges W. C., Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the C β subunit of protein kinase A. Journals of Gerontology A 2009 64 12 1221 1231 2-s2.0-75949106184 10.1093/gerona/glp133
82. Yan L., Vatner D. E., O'Connor J. P., Ivessa A., Ge H., Chen W., Hirotani S., Ishikawa Y., Sadoshima J., Vatner S. F., Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell 2007 130 2 247 258 2-s2.0-34447528668 10.1016/j.cell.2007.05.038
83. Yamazaki D., Horiuchi J., Nakagami Y., Nagano S., Tamura T., Saitoe M., The Drosophila DCO mutation suppresses age-related memory impairment without affecting lifespan. Nature Neuroscience 2007 10 4 478 484 2-s2.0-33947688760 10.1038/nn1863
84. Bordone L., Guarente L., Calorie restriction, SIRT1 and metabolism: understanding longevity. Nature Reviews Molecular Cell Biology 2005 6 4 298 305 2-s2.0-17144429302 10.1038/nrm1616
85. Polak P., Hall M. N., mTOR and the control of whole body metabolism. Current Opinion in Cell Biology 2009 21 2 209 218 2-s2.0-63749105226 10.1016/j.ceb.2009.01.024
86. Bissinger P. H., Wieser R., Hamilton B., Ruis H., Control of Saccharomyces cerevisiae catalase T gene (CTT1) expression by nutrient supply via the RAS-cyclic AMP pathway. Molecular and Cellular Biology 1989 9 3 1309 1315 2-s2.0-0024554046
87. Cha M.-K., Choi Y.-S., Hong S.-K., Kim W.-C., No K. T., Kim I.-H., Nuclear thiol peroxidase as a functional Alkyl-hydroperoxide reductase necessary for stationary phase growth of Saccharomyces cerevisiae. Journal of Biological Chemistry 2003 278 27 24636 24643 2-s2.0-0041589207 10.1074/jbc.M302628200
88. Hong S.-K., Cha M.-K., Choi Y.-S., Kim W.-C., Kim I.-H., Msn2p/Msn4p act as a key transcriptional activator of yeast cytoplasmic thiol peroxidase II. Journal of Biological Chemistry 2002 277 14 12109 12117 2-s2.0-0037023725 10.1074/jbc.M111341200
89. Park S. G., Cha M.-K., Jeong W., Kim I.-H., Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae. Journal of Biological Chemistry 2000 275 8 5723 5732 2-s2.0-0000056465 10.1074/jbc.275.8.5723
90. Aung-Htut M. T., Ayer A., Breitenbach M., Dawes I., Breitenbach M., Jazwinski S. M., Laun P., Oxidative stresses and ageing. Aging Research in Yeast 2012 57 chapter 2 Dordrecht, The Netherlands Springer 13 54 10.1007/978-94-007-2561-4
91. Wang Y., Pierce M., Schneper L., Güldal C. G., Zhang X., Tavazoie S., Broach J. R., Ras and Gpa2 mediate one branch of a redundant glucose signaling pathway in yeast. PLoS Biology 2004 2 5, e128 2-s2.0-19344365135 10.1371/journal.pbio.0020128
92. Santangelo G. M., Glucose signaling in Saccharomyces cerevisiae. Microbiology and Molecular Biology Reviews 2006 70 1 253 282 2-s2.0-33645130011 10.1128/MMBR.70.1.253-282.2006
93. Rubio-Texeira M., Van Zeebroeck G., Voordeckers K., Thevelein J. M., Saccharomyces cerevisiae plasma membrane nutrient sensors and their role in PKA signaling. FEMS Yeast Research 2010 10 2 134 149 2-s2.0-76349102304 10.1111/j.1567-1364.2009.00587.x
94. Broach J. R., Deschenes R. J., The function of ras genes in Saccharomyces cerevisiae. Advances in Cancer Research 1990 54 79 139 2-s2.0-0025253769
95. Colombo S., Ronchetti D., Thevelein J. M., Winderickx J., Martegani E., Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. Journal of Biological Chemistry 2004 279 45 46715 46722 2-s2.0-6344256284 10.1074/jbc.M405136200
96. Rolland F., De Winde J. H., Lemaire K., Boles E., Thevelein J. M., Winderickx J., Glucose-induced cAMP signalling in yeast requires both a G-protein coupled receptor system for extracellular glucose detection and a separable hexose kinase-dependent sensing process. Molecular Microbiology 2000 38 2 348 358 2-s2.0-0033745888 10.1046/j.1365-2958.2000.02125.x
97. Blair H. C., Teitelbaum S. L., Ghiselli R., Gluck S., Osteoclastic bone resorption by a polarized vacuolar proton pump. Science 1989 245 4920 855 857 2-s2.0-0024461376
98. Nanda A., Gukovskaya A., Tseng J., Grinstein S., Activation of vacuolar-type proton pumps by protein kinase C. Role in neutrophil pH regulation. Journal of Biological Chemistry 1992 267 32 22740 22746 2-s2.0-0026460154
99. Sennoune S. R., Bakunts K., Martínez G. M., Chua-Tuan J. L., Kebir Y., Attaya M. N., Martínez-Zaguilán R., Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity. American Journal of Physiology 2004 286 6 C1443 C1452 2-s2.0-2442560191 10.1152/ajpcell.00407.2003
100. Wagner C. A., Finberg K. E., Breton S., Marshansky V., Brown D., Geibel J. P., Renal vacuolar H+-ATPase. Physiological Reviews 2004 84 4 1263 1314 2-s2.0-4644245032 10.1152/physrev.00045.2003
101. Bond S., Forgac M., The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeast. Journal of Biological Chemistry 2008 283 52 36513 36521 2-s2.0-61349192268 10.1074/jbc.M805232200
102. Martínez-Muñoz G. A., Kane P., Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast. Journal of Biological Chemistry 2008 283 29 20309 20319 2-s2.0-50649120655 10.1074/jbc.M710470200
103. Kane P. M., The long physiological reach of the yeast vacuolar H+-ATPase. Journal of Bioenergetics and Biomembranes 2007 39 5-6 415 421 2-s2.0-38349193176 10.1007/s10863-007-9112-z
104. Li S. C., Kane P. M., The yeast lysosome-like vacuole: endpoint and crossroads. Biochimica et Biophysica Acta 2009 1793 4 650 663 2-s2.0-62949218373 10.1016/j.bbamcr.2008.08.003
105. Thorpe G. W., Fong C. S., Alic N., Higgins V. J., Dawes I. W., Cells have distinct mechanisms to maintain protection against different reactive oxygen species: oxidative-stress-response genes. Proceedings of the National Academy of Sciences of the United States of America 2004 101 17 6564 6569 2-s2.0-2342487990 10.1073/pnas.0305888101
106. Orij R., Postmus J., Beek A. T., Brul S., Smits G. J., In vivo measurement of cytosolic and mitochondrial pH using a pH-sensitive GFP derivative in Saccharomyces cerevisiae reveals a relation between intracellular pH and growth. Microbiology 2009 155 1 268 278 2-s2.0-61449216130 10.1099/mic.0.022038-0
107. Thevelein J. M., Beullens M., Honshoven F., Hoebeeck G., Detremerie K., Griewel B., den Hollander J. A., Jans A. W., Regulation of the cAMP level in the yeast Saccharomyces cerevisiae: the glucose-induced cAMP signal is not mediated by a transient drop in the intracellular pH. Journal of General Microbiology 1987 133 8 2197 2205 2-s2.0-0023393237
108. Goossens A., De la Fuente N., Forment J., Serrano R., Portillo F., Regulation of yeast H+-ATPase by protein kinases belonging to a family dedicated to activation of plasma membrane transporters. Molecular and Cellular Biology 2000 20 20 7654 7661 2-s2.0-0033800762 10.1128/MCB.20.20.7654-7661.2000
109. Sellier C., Bodart J.-F., Flament S., Baert F., Cannon J., Vilain J.-P., Intracellular acidification delays hormonal G2/M transition and inhibits G2/M transition triggered by thiophosphorylated MAPK in xenopus oocytes. Journal of Cellular Biochemistry 2006 98 2 287 300 2-s2.0-33646161947 10.1002/jcb.20764
110. Kane P. M., Disassembly and reassembly of the yeast vacuolar H+-ATPase in vivo. Journal of Biological Chemistry 1995 270 28 17025 17032 2-s2.0-0029063512
111. Parra K. J., Kane P. M., Reversible association between the V1 and V0 domains of yeast vacuolar H+-ATPase is an unconventional glucose-induced effect. Molecular and Cellular Biology 1998 18 12 7064 7074 2-s2.0-0031597366
112. Milgrom E., Diab H., Middleton F., Kane P. M., Loss of vacuolar proton-translocating ATPase activity in yeast results in chronic oxidative stress. Journal of Biological Chemistry 2007 282 10 7125 7136 2-s2.0-34147107933 10.1074/jbc.M608293200
113. Veatch J. R., McMurray M. A., Nelson Z. W., Gottschling D. E., Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 2009 137 7 1247 1258 2-s2.0-67549136242 10.1016/j.cell.2009.04.014
114. Garipler G., Dunn C. D., Defects associated with mitochondrial DNA damage can be mitigated by increased vacuolar pH in Saccharomyces cerevisiae. Genetics 2013 194 1 285 290
115. Diab H. I., Kane P. M., Loss of vacuolar H+-ATPase (V-ATPase) activity in yeast generates an iron deprivation signal that is moderated by induction of the peroxiredoxin TSA2. The Journal of Biological Chemistry 2013 288 16 11366 11377
116. Lee J., Spector D., Godon C., Labarre J., Toledano M. B., A new antioxidant with alkyl hydroperoxide defense properties in yeast. Journal of Biological Chemistry 1999 274 8 4537 4544 2-s2.0-0033582416 10.1074/jbc.274.8. 4537
117. Li L., Murdock G., Bagley D., Jia X., Ward D. M., Kaplan J., Genetic dissection of a mitochondria-vacuole signaling pathway in yeast reveals a link between chronic oxidative stress and vacuolar iron transport. Journal of Biological Chemistry 2010 285 14 10232 10242 2-s2.0-77951235682 10.1074/jbc.M109.096859
118. Wuttke D., Connor R., Vora C., Craig T., Li Y., Wood S., Vasieva O., Shmookler Reis R., Tang F., de Magalhaes J. P., Dissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes. PLoS Genetics 2012 8 8, article e1002834
119. Kispal G., Csere P., Guiard B., Lill R., The ABC transport Atm1p is required for mitochondrial iron homeostasis. FEBS Letters 1997 418 3 346 350 2-s2.0-0030608677 10.1016/S0014-5793(97)01414-2
120. Rutherford J. C., Ojeda L., Balk J., Mühlenhoff U., Lill R., Winge D. R., Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis. Journal of Biological Chemistry 2005 280 11 10135 10140 2-s2.0-15444371876 10.1074/jbc.M413731200
121. Follmann M., Ochrombel I., Krämer R., Trötschel C., Poetsch A., Rückert C., Hüser A., Persicke M., Seiferling D., Kalinowski J., Marin K., Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis. BMC Genomics 2009 10, article 621 2-s2.0-74549157678 10.1186/1471-2164-10-621
122. Li H., Mapolelo D. T., Dingra N. N., Keller G., Riggs-Gelasco P. J., Winge D. R., Johnson M. K., Outten C. E., Histidine 103 in Fra2 is an iron-sulfur cluster ligand in the [2Fe-2S] Fra2-Grx3 complex and is required for in vivo iron signaling in yeast. Journal of Biological Chemistry 2011 286 1 867 876 2-s2.0-78650949287 10.1074/jbc.M110.184176