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Volumn 492, Issue 7428, 2012, Pages 261-265

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

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AMINO ACID;

EID: 84871011474     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11654     Document Type: Article
Times cited : (414)

References (41)
  • 1
    • 38649132337 scopus 로고    scopus 로고
    • Mitochondria-a nexus for aging, calorie restriction, and sirtuins?
    • Guarente, L. Mitochondria-a nexus for aging, calorie restriction, and sirtuins? Cell 132, 171-176 (2008).
    • (2008) Cell , vol.132 , pp. 171-176
    • Guarente, L.1
  • 2
    • 77955351652 scopus 로고    scopus 로고
    • New insights into the role of mitochondria in aging: Mitochondrial dynamics and more
    • Seo, A. Y. et al. New insights into the role of mitochondria in aging: mitochondrial dynamics and more. J. Cell Sci. 123, 2533-2542 (2010).
    • (2010) J. Cell Sci , vol.123 , pp. 2533-2542
    • Seo, A.Y.1
  • 3
    • 35348972430 scopus 로고    scopus 로고
    • Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
    • Bishop, N. A. & Guarente, L. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nature Rev. Genet. 8, 835-844 (2007).
    • (2007) Nature Rev. Genet , vol.8 , pp. 835-844
    • Bishop, N.A.1    Guarente, L.2
  • 5
    • 62949218373 scopus 로고    scopus 로고
    • The yeast lysosome-like vacuole: Endpoint and crossroads
    • Li, S. C. & Kane, P. M. The yeast lysosome-like vacuole: endpoint and crossroads. Biochim. Biophys. Acta 1793, 650-663 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 650-663
    • Li, S.C.1    Kane, P.M.2
  • 6
    • 33845876643 scopus 로고    scopus 로고
    • Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models
    • Scheckhuber, C. Q. et al. Reducing mitochondrial fission results in increased life span and fitness of two fungal ageing models. Nature Cell Biol. 9, 99-105 (2007).
    • (2007) Nature Cell Biol , vol.9 , pp. 99-105
    • Scheckhuber, C.Q.1
  • 7
    • 79952450133 scopus 로고    scopus 로고
    • Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells
    • Lam, Y. T., Aung-Htut, M. T., Lim, Y. L., Yang, H. & Dawes, I. W. Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells. Free Radic. Biol. Med. 50, 963-970 (2011).
    • (2011) Free Radic. Biol. Med , vol.50 , pp. 963-970
    • Lam, Y.T.1    Aung-Htut, M.T.2    Lim, Y.L.3    Yang, H.4    Dawes, I.W.5
  • 8
    • 80052795422 scopus 로고    scopus 로고
    • Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast
    • McFaline-Figueroa, J. R. et al. Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast. Aging Cell 10, 885-895 (2011).
    • (2011) Aging Cell , vol.10 , pp. 885-895
    • McFaline-Figueroa, J.R.1
  • 9
    • 67549136242 scopus 로고    scopus 로고
    • Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect
    • Veatch, J. R., McMurray, M. A., Nelson, Z. W. & Gottschling, D. E. Mitochondrial dysfunction leads to nuclear genome instability via an iron-sulfur cluster defect. Cell 137, 1247-1258 (2009).
    • (2009) Cell , vol.137 , pp. 1247-1258
    • Veatch, J.R.1    McMurray, M.A.2    Nelson, Z.W.3    Gottschling, D.E.4
  • 10
    • 70649106968 scopus 로고    scopus 로고
    • The mother enrichment program: A genetic systemfor facile replicative life span analysis in Saccharomyces cerevisiae
    • Lindstrom, D. L. & Gottschling, D. E. The mother enrichment program: a genetic systemfor facile replicative life span analysis in Saccharomyces cerevisiae. Genetics 183, 413-422 (2009).
    • (2009) Genetics , vol.183 , pp. 413-422
    • Lindstrom, D.L.1    Gottschling, D.E.2
  • 11
    • 0024306295 scopus 로고
    • Fluorescence microscopy methods for yeast
    • Pringle, J. R. et al. Fluorescence microscopy methods for yeast. Methods Cell Biol. 31, 357-435 (1989).
    • (1989) Methods Cell Biol , vol.31 , pp. 357-435
    • Pringle, J.R.1
  • 12
    • 0036198860 scopus 로고    scopus 로고
    • Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae
    • Dimmer, K. S. et al. Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol. Biol. Cell 13, 847-853 (2002).
    • (2002) Mol. Biol. Cell , vol.13 , pp. 847-853
    • Dimmer, K.S.1
  • 13
    • 27644467457 scopus 로고    scopus 로고
    • Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae.Mol
    • Altmann, K. & Westermann, B. Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae.Mol. Biol. Cell16,5410-5417(2005).
    • (2005) Biol. Cell , vol.16 , pp. 5410-5417
    • Altmann, K.1    Westermann, B.2
  • 14
    • 0025240361 scopus 로고
    • Molecular structure of a gene,VMA1, encoding the catalytic subunit of H1-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae
    • Hirata, R. et al. Molecular structure of a gene,VMA1, encoding the catalytic subunit of H1-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J. Biol. Chem. 265, 6726-6733 (1990).
    • (1990) J. Biol. Chem , vol.265 , pp. 6726-6733
    • Hirata, R.1
  • 15
    • 0030845189 scopus 로고    scopus 로고
    • VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H1-ATPase assembly
    • Jackson, D. D. & Stevens, T. H. VMA12 encodes a yeast endoplasmic reticulum protein required for vacuolar H1-ATPase assembly. J. Biol. Chem. 272, 25928-25934 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 25928-25934
    • Jackson, D.D.1    Stevens, T.H.2
  • 16
    • 0027322674 scopus 로고
    • Inhibitory effect of modified bafilomycins and concanamycins on P-and V-type adenosinetriphosphatases
    • Droese, S. et al. Inhibitory effect of modified bafilomycins and concanamycins on P-and V-type adenosinetriphosphatases. Biochemistry 32, 3902-3906 (1993).
    • (1993) Biochemistry , vol.32 , pp. 3902-3906
    • Droese, S.1
  • 17
    • 0023432180 scopus 로고
    • Multiplemethods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle
    • Weisman, L. S., Bacallao, R.&Wickner, W.Multiplemethods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle. J. Cell Biol. 105, 1539-1547 (1987).
    • (1987) J. Cell Biol , vol.105 , pp. 1539-1547
    • Weisman, L.S.1    Bacallao, R.2    Wickner, W.3
  • 18
    • 0033803597 scopus 로고    scopus 로고
    • The use of pHluorins for optical measurements of presynaptic activity
    • Sankaranarayanan, S., De Angelis, D., Rothman, J. E. & Ryan, T. A. The use of pHluorins for optical measurements of presynaptic activity. Biophys. J. 79, 2199-2208 (2000).
    • (2000) Biophys. J , vol.79 , pp. 2199-2208
    • Sankaranarayanan, S.1    De Angelis, D.2    Rothman, J.E.3    Ryan, T.A.4
  • 19
    • 0037130175 scopus 로고    scopus 로고
    • Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
    • Lin, S. J. et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418, 344-348 (2002).
    • (2002) Nature , vol.418 , pp. 344-348
    • Lin, S.J.1
  • 20
    • 27744511769 scopus 로고    scopus 로고
    • Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
    • Kaeberlein, M. et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310, 1193-1196 (2005).
    • (2005) Science , vol.310 , pp. 1193-1196
    • Kaeberlein, M.1
  • 21
    • 34347392289 scopus 로고    scopus 로고
    • The structure and function of Saccharomyces cerevisiae proteinase A
    • Parr, C. L., Keates, R. A., Bryksa, B. C., Ogawa, M. & Yada, R. Y. The structure and function of Saccharomyces cerevisiae proteinase A. Yeast 24, 467-480 (2007).
    • (2007) Yeast , vol.24 , pp. 467-480
    • Parr, C.L.1    Keates, R.A.2    Bryksa, B.C.3    Ogawa, M.4    Yada, R.Y.5
  • 22
    • 14244258606 scopus 로고    scopus 로고
    • A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae
    • Shimazu, M., Sekito, T., Akiyama, K., Ohsumi, Y. & Kakinuma, Y. A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J. Biol. Chem. 280, 4851-4857 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 4851-4857
    • Shimazu, M.1    Sekito, T.2    Akiyama, K.3    Ohsumi, Y.4    Kakinuma, Y.5
  • 23
    • 0032588195 scopus 로고    scopus 로고
    • The vacuolar Ca21/H1 exchanger Vcx1p/Hum1p tightly controls cytosolic Ca21 levels in S. cerevisiae
    • Miseta, A., Kellermayer, R., Aiello, D. P., Fu, L. & Bedwell, D. M. The vacuolar Ca21/H1 exchanger Vcx1p/Hum1p tightly controls cytosolic Ca21 levels in S. cerevisiae. FEBS Lett. 451, 132-136 (1999).
    • (1999) FEBS Lett , vol.451 , pp. 132-136
    • Miseta, A.1    Kellermayer, R.2    Aiello, D.P.3    Fu, L.4    Bedwell, D.M.5
  • 24
    • 0030704674 scopus 로고    scopus 로고
    • Intracellular sequestration of sodium by a novel Na1/H1 exchanger in yeast is enhanced by mutations in the plasma membrane H1-ATPase. Insights into mechanisms of sodium tolerance
    • Nass, R., Cunningham, K. W. & Rao, R. Intracellular sequestration of sodium by a novel Na1/H1 exchanger in yeast is enhanced by mutations in the plasma membrane H1-ATPase. Insights into mechanisms of sodium tolerance. J. Biol. Chem. 272, 26145-26152 (1997).
    • (1997) J. Biol. Chem , vol.272 , pp. 26145-26152
    • Nass, R.1    Cunningham, K.W.2    Rao, R.3
  • 25
    • 0035968245 scopus 로고    scopus 로고
    • A family of yeast proteinsmediating bidirectional vacuolar aminoacid transport
    • Russnak, R., Konczal, D. & Mcintire, S. L. A family of yeast proteinsmediating bidirectional vacuolar aminoacid transport. J. Biol.Chem.276,23849-23857(2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 23849-23857
    • Russnak, R.1    Konczal, D.2    McIntire, S.L.3
  • 26
    • 0034703217 scopus 로고    scopus 로고
    • Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
    • Lin, S. J., Defossez, P. A. & Guarente, L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289, 2126-2128 (2000).
    • (2000) Science , vol.289 , pp. 2126-2128
    • Lin, S.J.1    Defossez, P.A.2    Guarente, L.3
  • 27
    • 19344374925 scopus 로고    scopus 로고
    • Sir2-independent life span extension by calorie restriction in yeast
    • Kaeberlein, M., Kirkland, K. T., Fields, S.&Kennedy, B. K. Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol. 2, e296 (2004).
    • (2004) PLoS Biol , vol.2
    • Kaeberlein, M.1    Kirkland, K.T.2    Fields, S.3    Kennedy, B.K.4
  • 28
    • 0025232840 scopus 로고
    • Cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein
    • Tanaka, K. et al. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell 60, 803-807 (1990).
    • (1990) Cell , vol.60 , pp. 803-807
    • Tanaka, K.1
  • 29
    • 33748976734 scopus 로고    scopus 로고
    • Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins
    • Palmieri, F. et al. Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins. Biochim. Biophys. Acta 1757, 1249-1262 (2006).
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 1249-1262
    • Palmieri, F.1
  • 31
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
    • Baker Brachmann, C. et al. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14, 115-132 (1998).
    • (1998) Yeast , vol.14 , pp. 115-132
    • Baker Brachmann, C.1
  • 32
    • 3042722112 scopus 로고    scopus 로고
    • Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae
    • Sheff, M. A. & Thorn, K. S. Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae. Yeast 21, 661-670 (2004).
    • (2004) Yeast , vol.21 , pp. 661-670
    • Sheff, M.A.1    Thorn, K.S.2
  • 33
    • 11144267737 scopus 로고    scopus 로고
    • Improved monomeric red, orange and yellow fluorescent proteins derived fromDiscosoma sp. red fluorescent protein
    • Shaner, N. C. et al. Improved monomeric red, orange and yellow fluorescent proteins derived fromDiscosoma sp. red fluorescent protein. Nature Biotechnol.22, 1567-1572 (2004).
    • (2004) Nature Biotechnol , vol.22 , pp. 1567-1572
    • Shaner, N.C.1
  • 34
    • 0142184341 scopus 로고    scopus 로고
    • Global analysis of protein localization in budding yeast
    • Huh, W.-K. et al. Global analysis of protein localization in budding yeast. Nature 425, 686-691 (2003).
    • (2003) Nature , vol.425 , pp. 686-691
    • Huh, W.-K.1
  • 35
    • 35349022993 scopus 로고    scopus 로고
    • A suite of Gateway cloning vectors for highthroughputgeneticanalysis inSaccharomyces cerevisiae
    • Alberti, S., Gitler, A. D. & Lindquist, S. A suite of Gateway cloning vectors for highthroughputgeneticanalysis inSaccharomyces cerevisiae. Yeast 24,913-919(2007).
    • (2007) Yeast , vol.24 , pp. 913-919
    • Alberti, S.1    Gitler, A.D.2    Lindquist, S.3
  • 36
    • 34147092780 scopus 로고    scopus 로고
    • Approaching a complete repository of sequence-verified proteinencoding clones for Saccharomyces cerevisiae
    • Hu, Y. et al. Approaching a complete repository of sequence-verified proteinencoding clones for Saccharomyces cerevisiae. Genome Res. 17, 536-543 (2007).
    • (2007) Genome Res , vol.17 , pp. 536-543
    • Hu, Y.1
  • 37
  • 38
    • 79953758066 scopus 로고    scopus 로고
    • Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae
    • Lindstrom, D. L., Leverich, C. K., Henderson, K. A.&Gottschling, D. E. Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. PLoS Genet. 7, e1002015 (2011).
    • (2011) PLoS Genet , vol.7
    • Lindstrom, D.L.1    Leverich, C.K.2    Henderson, K.A.3    Gottschling, D.E.4
  • 39
    • 0028035426 scopus 로고
    • Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast
    • Morano, K. A. & Klionsky, D. J. Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast. J. Cell Sci. 107, 2813-2824 (1994).
    • (1994) J. Cell Sci , vol.107 , pp. 2813-2824
    • Morano, K.A.1    Klionsky, D.J.2
  • 40
    • 0033601359 scopus 로고    scopus 로고
    • Alternativemechanismsof vacuolar acidification in H1-ATPase-deficient yeast
    • Plant, P. J.,Manolson, M. F., Grinstein, S.&Demaurex, N. Alternativemechanismsof vacuolar acidification in H1-ATPase-deficient yeast. J. Biol. Chem. 274, 37270-37279 (1999).
    • (1999) J. Biol. Chem , vol.274 , pp. 37270-37279
    • Plant, P.J.1    Manolson, M.F.2    Grinstein, S.3    Demaurex, N.4
  • 41
    • 40149109321 scopus 로고    scopus 로고
    • Asystematic library for comprehensive overexpressionscreens in Saccharomyces cerevisiae
    • Jones, G. M. et al.Asystematic library for comprehensive overexpressionscreens in Saccharomyces cerevisiae. Nature Methods 5, 239-241 (2008).
    • (2008) Nature Methods , vol.5 , pp. 239-241
    • Jones, G.M.1


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