메뉴 건너뛰기




Volumn 5, Issue 1, 2010, Pages 39-49

Mitochondrial stress and the pathogenesis of diabetic neuropathy

Author keywords

Calcium; Dorsal root ganglia; Electron transport chain; Mitochondrial trafficking; Reactive oxygen species; Respiration; Sensory polyneuropathy; Sympathetic neuropathy

Indexed keywords

CALCIUM ION; REACTIVE OXYGEN METABOLITE;

EID: 77949806078     PISSN: 17446651     EISSN: None     Source Type: Journal    
DOI: 10.1586/eem.09.55     Document Type: Review
Times cited : (116)

References (131)
  • 1
    • 20144389036 scopus 로고    scopus 로고
    • Sural nerve pathology in diabetic patients with minimal but progressive neuropathy
    • Malik RA, Tesfaye S, Newrick PG et al. Sural nerve pathology in diabetic patients with minimal but progressive neuropathy. Diabetologia 48(3), 578-585 (2005).
    • (2005) Diabetologia , vol.48 , Issue.3 , pp. 578-585
    • Malik, R.A.1    Tesfaye, S.2    Newrick, P.G.3
  • 2
    • 2442492883 scopus 로고    scopus 로고
    • Diabetic neuropathy in Type 1 and Type 2 diabetes and the effects of C-peptide
    • Sima AA. Diabetic neuropathy in Type 1 and Type 2 diabetes and the effects of C-peptide. J. Neurol. Sci. 220(1-2), 133-136 (2004).
    • (2004) J. Neurol. Sci. , vol.220 , Issue.1-2 , pp. 133-136
    • Sima, A.A.1
  • 3
    • 0031290499 scopus 로고    scopus 로고
    • Pathogenetic mechanisms of diabetic neuropathy: Lessons from animal models
    • Yagihashi S. Pathogenetic mechanisms of diabetic neuropathy: lessons from animal models. J. Peripher. Nerv. Syst. 2(2), 113-132 (1997).
    • (1997) J. Peripher. Nerv. Syst. , vol.2 , Issue.2 , pp. 113-132
    • Yagihashi, S.1
  • 5
    • 0042405193 scopus 로고    scopus 로고
    • Diabetic autonomic neuropathy
    • DOI 10.2337/diacare.26.5.1553
    • Vinik AI, Maser RE, Mitchell BD, Freeman R. Diabetic autonomic neuropathy. Diabetes Care 26(5), 1553-1579 (2003). (Pubitemid 36934465)
    • (2003) Diabetes Care , vol.26 , Issue.5 , pp. 1553-1579
    • Vinik, A.I.1    Maser, R.E.2    Mitchell, B.D.3    Freeman, R.4
  • 6
    • 3142557927 scopus 로고    scopus 로고
    • The time course of epidermal nerve fibre regeneration: Studies in normal controls and in people with diabetes, with and without neuropathy
    • Polydefkis M, Hauer P, Sheth S, Sirdofsky M, Griffin JW, McArthur JC. The time course of epidermal nerve fibre regeneration: studies in normal controls and in people with diabetes, with and without neuropathy. Brain 127(Pt 7), 1606-1615 (2004).
    • (2004) Brain , vol.127 , Issue.PART 7 , pp. 1606-1615
    • Polydefkis, M.1    Hauer, P.2    Sheth, S.3    Sirdofsky, M.4    Griffin, J.W.5    McArthur, J.C.6
  • 7
    • 9744252312 scopus 로고    scopus 로고
    • Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes
    • Burnand RC, Price SA, McElhaney M, Barker D, Tomlinson DR. Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes. Brain Res. Mol. Brain Res. 132(2), 235-240 (2004).
    • (2004) Brain Res. Mol. Brain Res. , vol.132 , Issue.2 , pp. 235-240
    • Burnand, R.C.1    Price, S.A.2    McElhaney, M.3    Barker, D.4    Tomlinson, D.R.5
  • 8
    • 0042822014 scopus 로고    scopus 로고
    • Sensory neurons with activated caspase-3 survive long-term experimental diabetes
    • Cheng C, Zochodne DW. Sensory neurons with activated caspase-3 survive long-term experimental diabetes. Diabetes 52(9), 2363-2371 (2003).
    • (2003) Diabetes , vol.52 , Issue.9 , pp. 2363-2371
    • Cheng, C.1    Zochodne, D.W.2
  • 9
    • 34250330253 scopus 로고    scopus 로고
    • Degeneration of the Golgi and neuronal loss in dorsal root ganglia in diabetic BioBreeding/Worcester rats
    • Kamiya H, Zhang W, Sima AA. Degeneration of the Golgi and neuronal loss in dorsal root ganglia in diabetic BioBreeding/Worcester rats. Diabetologia 49(11), 2763-2774 (2006).
    • (2006) Diabetologia , vol.49 , Issue.11 , pp. 2763-2774
    • Kamiya, H.1    Zhang, W.2    Sima, A.A.3
  • 11
    • 0018888398 scopus 로고
    • Reduced perikaryal volume of lower motor and primary sensory neurons in early experimental diabetes
    • Sidenius P, Jakobsen J. Reduced perikaryal volume of lower motor and primary sensory neurons in early experimental diabetes. Diabetes 29(3), 182-186 (1980).
    • (1980) Diabetes , vol.29 , Issue.3 , pp. 182-186
    • Sidenius, P.1    Jakobsen, J.2
  • 12
    • 14644410374 scopus 로고    scopus 로고
    • Experimental diabetic neuropathy with spontaneous recovery: Is there irreparable damage?
    • Kennedy JM, Zochodne DW. Experimental diabetic neuropathy with spontaneous recovery: is there irreparable damage? Diabetes 54(3), 830-837 (2005).
    • (2005) Diabetes , vol.54 , Issue.3 , pp. 830-837
    • Kennedy, J.M.1    Zochodne, D.W.2
  • 13
    • 0029829783 scopus 로고    scopus 로고
    • Quantitation of epidermal nerves in diabetic neuropathy
    • Kennedy WR, Wendelschafer-Crabb G, Johnson T. Quantitation of epidermal nerves in diabetic neuropathy. Neurology 47(4), 1042-1048 (1996).
    • (1996) Neurology , vol.47 , Issue.4 , pp. 1042-1048
    • Kennedy, W.R.1    Wendelschafer-Crabb, G.2    Johnson, T.3
  • 14
    • 34848915458 scopus 로고    scopus 로고
    • Denervation of skin in neuropathies: The sequence of axonal and Schwann cell changes in skin biopsies
    • Ebenezer GJ, McArthur JC, Thomas D et al. Denervation of skin in neuropathies: the sequence of axonal and Schwann cell changes in skin biopsies. Brain 130(Pt 10), 2703-2714 (2007).
    • (2007) Brain , vol.130 , Issue.PART 10 , pp. 2703-2714
    • Ebenezer, G.J.1    McArthur, J.C.2    Thomas, D.3
  • 15
    • 0042836677 scopus 로고    scopus 로고
    • Axonal swellings predict the degeneration of epidermal nerve fibers in painful neuropathies
    • Lauria G, Morbin M, Lombardi R et al. Axonal swellings predict the degeneration of epidermal nerve fibers in painful neuropathies. Neurology 61(5), 631-636 (2003).
    • (2003) Neurology , vol.61 , Issue.5 , pp. 631-636
    • Lauria, G.1    Morbin, M.2    Lombardi, R.3
  • 16
    • 0036356058 scopus 로고    scopus 로고
    • Neuropathology and pathogenesis of diabetic autonomic neuropathy
    • Schmidt RE. Neuropathology and pathogenesis of diabetic autonomic neuropathy. Int. Rev. Neurobiol. 50, 257-292 (2002).
    • (2002) Int. Rev. Neurobiol. , vol.50 , pp. 257-292
    • Schmidt, R.E.1
  • 18
    • 0017816844 scopus 로고
    • The effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig
    • Nja A, Purves D. The effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig. J. Physiol. 277, 53-75 (1978).
    • (1978) J. Physiol. , vol.277 , pp. 53-75
    • Nja, A.1    Purves, D.2
  • 19
    • 4143110556 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of diabetic neuropathy
    • Vincent AM, Russell JW, Low P, Feldman EL. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 25(4), 612-628 (2004).
    • (2004) Endocr. Rev. , vol.25 , Issue.4 , pp. 612-628
    • Vincent, A.M.1    Russell, J.W.2    Low, P.3    Feldman, E.L.4
  • 20
    • 0036356513 scopus 로고    scopus 로고
    • How does glucose generate oxidative stress in peripheral nerve?
    • Obrosova IG. How does glucose generate oxidative stress in peripheral nerve? Int. Rev. Neurobiol. 50, 3-35 (2002).
    • (2002) Int. Rev. Neurobiol. , vol.50 , pp. 3-35
    • Obrosova, I.G.1
  • 21
    • 0035195970 scopus 로고    scopus 로고
    • Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy
    • Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 44(11), 1973-1988 (2001).
    • (2001) Diabetologia , vol.44 , Issue.11 , pp. 1973-1988
    • Cameron, N.E.1    Eaton, S.E.2    Cotter, M.A.3    Tesfaye, S.4
  • 22
    • 0037402505 scopus 로고    scopus 로고
    • The role of oxidative stress in diabetic vascular and neural disease
    • Yorek MA. The role of oxidative stress in diabetic vascular and neural disease. Free Radic. Res. 37(5), 471-480 (2003).
    • (2003) Free Radic. Res. , vol.37 , Issue.5 , pp. 471-480
    • Yorek, M.A.1
  • 23
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • Nishikawa T, Edelstein D, Du XL et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404(6779), 787-790 (2000).
    • (2000) Nature , vol.404 , Issue.6779 , pp. 787-790
    • Nishikawa, T.1    Edelstein, D.2    Du, X.L.3
  • 24
    • 0036845661 scopus 로고    scopus 로고
    • High glucose-induced oxidative stress and mitochondrial dysfunction in neurons
    • Russell JW, Golovoy D, Vincent AM et al. High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J. 16(13), 1738-1748 (2002).
    • (2002) FASEB J. , vol.16 , Issue.13 , pp. 1738-1748
    • Russell, J.W.1    Golovoy, D.2    Vincent, A.M.3
  • 25
    • 0035430412 scopus 로고    scopus 로고
    • Effect of antioxidant treatment of streptozotocininduced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve
    • Coppey LJ, Gellett JS, Davidson EP, Dunlap JA, Lund DD, Yorek MA. Effect of antioxidant treatment of streptozotocininduced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50(8), 1927-1937 (2001).
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1927-1937
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Lund, D.D.5    Yorek, M.A.6
  • 26
    • 0036194243 scopus 로고    scopus 로고
    • Changes in endoneurial blood flow, motor nerve conduction velocity and vascular relaxation of epineurial arterioles of the sciatic nerve in ZDF-obese diabetic rats
    • Coppey LJ, Gellett JS, Davidson EP, Dunlap JA, Yorek MA. Changes in endoneurial blood flow, motor nerve conduction velocity and vascular relaxation of epineurial arterioles of the sciatic nerve in ZDF-obese diabetic rats. Diabetes Metab. Res. Rev. 18(1), 49-56 (2002).
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , Issue.1 , pp. 49-56
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Yorek, M.A.5
  • 27
    • 0037245335 scopus 로고    scopus 로고
    • Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation
    • Coppey LJ, Gellett JS, Davidson EP, Yorek MA. Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation. Free Radic. Res. 37(1), 33-40 (2003).
    • (2003) Free Radic. Res. , vol.37 , Issue.1 , pp. 33-40
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Yorek, M.A.4
  • 28
    • 0036357657 scopus 로고    scopus 로고
    • An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense
    • Obrosova IG, Van Huysen C, Fathallah L, Cao XC, Greene DA, Stevens MJ. An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense. FASEB J. 16(1), 123-125 (2002).
    • (2002) FASEB J. , vol.16 , Issue.1 , pp. 123-125
    • Obrosova, I.G.1    Van Huysen, C.2    Fathallah, L.3    Cao, X.C.4    Greene, D.A.5    Stevens, M.J.6
  • 29
    • 33845523337 scopus 로고    scopus 로고
    • The leptin-deficient (ob/ob) mouse: A new animal model of peripheral neuropathy of Type 2 diabetes and obesity
    • Drel VR, Mashtalir N, Ilnytska O et al. The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of Type 2 diabetes and obesity. Diabetes 55(12), 3335-3343 (2006).
    • (2006) Diabetes , vol.55 , Issue.12 , pp. 3335-3343
    • Drel, V.R.1    Mashtalir, N.2    Ilnytska, O.3
  • 30
    • 34547399482 scopus 로고    scopus 로고
    • High-fat diet induced neuropathy of pre-diabetes and obesity: Effects of"healthy" diet and aldose reductase inhibition
    • Obrosova IG, Ilnytska O, Lyzogubov VV et al. High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition. Diabetes 56(10), 2598-2608 (2007).
    • (2007) Diabetes , vol.56 , Issue.10 , pp. 2598-2608
    • Obrosova, I.G.1    Ilnytska, O.2    Lyzogubov, V.V.3
  • 31
    • 33644681565 scopus 로고    scopus 로고
    • Oxidative-nitrosative stress and poly(ADPRibose) polymerase (PARP) activation in experimental diabetic neuropathy: The relation is revisited
    • Obrosova IG, Drel VR, Pacher P et al. Oxidative-nitrosative stress and poly(ADPRibose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited. Diabetes 54(12), 3435-3441 (2005).
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3435-3441
    • Obrosova, I.G.1    Drel, V.R.2    Pacher, P.3
  • 32
    • 12144279066 scopus 로고    scopus 로고
    • Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADPribose) polymerase activation in tissue sites for diabetes complications
    • Obrosova IG, Pacher P, Szabo C et al. Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADPribose) polymerase activation in tissue sites for diabetes complications. Diabetes 54(1), 234-242 (2005).
    • (2005) Diabetes , vol.54 , Issue.1 , pp. 234-242
    • Obrosova, I.G.1    Pacher, P.2    Szabo, C.3
  • 33
    • 33747069158 scopus 로고    scopus 로고
    • Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage
    • Ho EC, Lam KS, Chen YS et al. Aldose reductase-deficient mice are protected from delayed motor nerve conduction velocity, increased c-Jun NH2-terminal kinase activation, depletion of reduced glutathione, increased superoxide accumulation, and DNA damage. Diabetes 55(7), 1946-1953 (2006).
    • (2006) Diabetes , vol.55 , Issue.7 , pp. 1946-1953
    • Ho, E.C.1    Lam, K.S.2    Chen, Y.S.3
  • 35
    • 66649095843 scopus 로고    scopus 로고
    • Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: Role of glucose-induced oxidative stress
    • Zherebitskaya E, Akude E, Smith DR, Fernyhough P. Development of selective axonopathy in adult sensory neurons isolated from diabetic rats: role of glucose-induced oxidative stress. Diabetes 58(6), 1356-1364 (2009).
    • (2009) Diabetes , vol.58 , Issue.6 , pp. 1356-1364
    • Zherebitskaya, E.1    Akude, E.2    Smith, D.R.3    Fernyhough, P.4
  • 36
    • 70349297369 scopus 로고    scopus 로고
    • Diabetes and the peripheral nerve
    • Obrosova IG. Diabetes and the peripheral nerve. Biochim. Biophys. Acta 1792(10), 931-940 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1792 , Issue.10 , pp. 931-940
    • Obrosova, I.G.1
  • 38
    • 0029086064 scopus 로고
    • Voltagedependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat
    • Hall KE, Sima AA, Wiley JW. Voltagedependent calcium currents are enhanced in dorsal root ganglion neurones from the Bio Bred/Worchester diabetic rat. J. Physiol. 486(Pt 2), 313-322 (1995).
    • (1995) J. Physiol. , vol.486 , Issue.PART 2 , pp. 313-322
    • Hall, K.E.1    Sima, A.A.2    Wiley, J.W.3
  • 39
    • 0035988192 scopus 로고    scopus 로고
    • Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3
    • Huang TJ, Sayers NM, Fernyhough P, Verkhratsky A. Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin- diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3. Diabetologia 45(4), 560-570 (2002).
    • (2002) Diabetologia , vol.45 , Issue.4 , pp. 560-570
    • Huang, T.J.1    Sayers, N.M.2    Fernyhough, P.3    Verkhratsky, A.4
  • 40
    • 3442902549 scopus 로고    scopus 로고
    • Diabetes-induced abnormalities in ER calcium mobilization in primary and secondary nociceptive neurons
    • Kruglikov I, Gryshchenko O, Shutov L, Kostyuk E, Kostyuk P, Voitenko N. Diabetes-induced abnormalities in ER calcium mobilization in primary and secondary nociceptive neurons. Pflugers Arch. 448(4), 395-401 (2004).
    • (2004) Pflugers Arch , vol.448 , Issue.4 , pp. 395-401
    • Kruglikov, I.1    Gryshchenko, O.2    Shutov, L.3    Kostyuk, E.4    Kostyuk, P.5    Voitenko, N.6
  • 41
    • 44749091551 scopus 로고    scopus 로고
    • Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes
    • Verkhratsky A, Fernyhough P. Mitochondrial malfunction and Ca2+ dyshomeostasis drive neuronal pathology in diabetes. Cell Calcium 44(1), 112-122 (2008).
    • (2008) Cell Calcium , vol.44 , Issue.1 , pp. 112-122
    • Verkhratsky, A.1    Fernyhough, P.2
  • 42
    • 0033857531 scopus 로고    scopus 로고
    • The missing link: A single unifying mechanism for diabetic complications
    • Nishikawa T, Edelstein D, Brownlee M. The missing link: a single unifying mechanism for diabetic complications. Kidney Int. 58(Suppl. 77), S26-S30 (2000).
    • (2000) Kidney Int , vol.58 , Issue.SUPPL. 77
    • Nishikawa, T.1    Edelstein, D.2    Brownlee, M.3
  • 43
    • 0031884263 scopus 로고    scopus 로고
    • Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy
    • Kalichman MW, Powell HC, Mizisin AP. Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy. Acta Neuropathol. 95(1), 47-56 (1998).
    • (1998) Acta Neuropathol , vol.95 , Issue.1 , pp. 47-56
    • Kalichman, M.W.1    Powell, H.C.2    Mizisin, A.P.3
  • 44
    • 33644680351 scopus 로고    scopus 로고
    • Apoptotic stress is counterbalanced by survival elements preventing programmed cell death of dorsal root ganglions in subacute Type 1 diabetic BB/Wor rats
    • Kamiya H, Zhangm W, Sima AA. Apoptotic stress is counterbalanced by survival elements preventing programmed cell death of dorsal root ganglions in subacute Type 1 diabetic BB/Wor rats. Diabetes 54(11), 3288-3295 (2005).
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3288-3295
    • Kamiya, H.1    Zhangm, W.2    Sima, A.A.3
  • 45
    • 0030786038 scopus 로고    scopus 로고
    • Axonal cytoskeletal pathology in aged and diabetic human sympathetic autonomic ganglia
    • Schmidt RE, Beaudet LN, Plurad SB, Dorsey DA. Axonal cytoskeletal pathology in aged and diabetic human sympathetic autonomic ganglia. Brain Res. 769(2), 375-383 (1997).
    • (1997) Brain Res , vol.769 , Issue.2 , pp. 375-383
    • Schmidt, R.E.1    Beaudet, L.N.2    Plurad, S.B.3    Dorsey, D.A.4
  • 46
    • 3042742246 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: Interactions with aldose reductase
    • Price SA, Agthong S, Middlemas AB, Tomlinson DR. Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy: interactions with aldose reductase. Diabetes 53(7), 1851-1856 (2004).
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1851-1856
    • Price, S.A.1    Agthong, S.2    Middlemas, A.B.3    Tomlinson, D.R.4
  • 48
    • 0041765665 scopus 로고    scopus 로고
    • Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of Type 1 diabetic rats in the presence of sustained hyperglycemia
    • Huang TJ, Price SA, Chilton L et al. Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of Type 1 diabetic rats in the presence of sustained hyperglycemia. Diabetes 52(8), 2129-2136 (2003).
    • (2003) Diabetes , vol.52 , Issue.8 , pp. 2129-2136
    • Huang, T.J.1    Price, S.A.2    Chilton, L.3
  • 49
    • 19344374717 scopus 로고    scopus 로고
    • Neurotrophin-3 prevents mitochondrial dysfunction in sensory neurons of streptozotocin-diabetic rats
    • Huang TJ, Sayers NM, Verkhratsky A, Fernyhough P. Neurotrophin-3 prevents mitochondrial dysfunction in sensory neurons of streptozotocin-diabetic rats. Exp. Neurol. 194(1), 279-283 (2005).
    • (2005) Exp. Neurol. , vol.194 , Issue.1 , pp. 279-283
    • Huang, T.J.1    Sayers, N.M.2    Verkhratsky, A.3    Fernyhough, P.4
  • 50
    • 0033760829 scopus 로고    scopus 로고
    • Diabetic peripheral neuropathy: Evidence for apoptosis and associated mitochondrial dysfunction
    • Srinivasan S, Stevens M, Wiley JW. Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction. Diabetes 49(11), 1932-1938 (2000).
    • (2000) Diabetes , vol.49 , Issue.11 , pp. 1932-1938
    • Srinivasan, S.1    Stevens, M.2    Wiley, J.W.3
  • 51
    • 10644221251 scopus 로고    scopus 로고
    • Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons
    • Huang TJ, Verkhratsky A, Fernyhough P. Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons. Mol. Cell. Neurosci. 28(1), 42-54 (2005).
    • (2005) Mol. Cell. Neurosci. , vol.28 , Issue.1 , pp. 42-54
    • Huang, T.J.1    Verkhratsky, A.2    Fernyhough, P.3
  • 52
    • 0035158585 scopus 로고    scopus 로고
    • A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy
    • Purves T, Middlemas A, Agthong S et al. A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy. FASEB J. 15(13), 2508-2514 (2001).
    • (2001) FASEB J. , vol.15 , Issue.13 , pp. 2508-2514
    • Purves, T.1    Middlemas, A.2    Agthong, S.3
  • 53
    • 38649110117 scopus 로고    scopus 로고
    • Hyperglycaemia inhibits Schwann cell proliferation and migration and restricts regeneration of axons and Schwann cells from adult murine DRG
    • Gumy LF, Bampton ET, Tolkovsky AM. Hyperglycaemia inhibits Schwann cell proliferation and migration and restricts regeneration of axons and Schwann cells from adult murine DRG. Mol. Cell. Neurosci. 37(2), 298-311 (2008).
    • (2008) Mol. Cell. Neurosci. , vol.37 , Issue.2 , pp. 298-311
    • Gumy, L.F.1    Bampton, E.T.2    Tolkovsky, A.M.3
  • 54
    • 46749114863 scopus 로고    scopus 로고
    • Hyperglycemia and downregulation of caveolin-1 enhance neuregulin-induced demyelination
    • Yu C, Rouen S, Dobrowsky RT. Hyperglycemia and downregulation of caveolin-1 enhance neuregulin-induced demyelination. Glia 56(8), 877-887 (2008).
    • (2008) Glia , vol.56 , Issue.8 , pp. 877-887
    • Yu, C.1    Rouen, S.2    Dobrowsky, R.T.3
  • 55
    • 0034896185 scopus 로고    scopus 로고
    • Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy
    • Hall KE, Liu J, Sima AA, Wiley JW. Impaired inhibitory G-protein function contributes to increased calcium currents in rats with diabetic neuropathy. J. Neurophysiol. 86(2), 760-770 (2001).
    • (2001) J. Neurophysiol. , vol.86 , Issue.2 , pp. 760-770
    • Hall, K.E.1    Liu, J.2    Sima, A.A.3    Wiley, J.W.4
  • 56
    • 0029012204 scopus 로고
    • Calcium signal prolongation in sensory neurones of mice with experimental diabetes
    • Kostyuk E, Pronchuk N, Shmigol A. Calcium signal prolongation in sensory neurones of mice with experimental diabetes. Neuroreport 6(7), 1010-1012 (1995).
    • (1995) Neuroreport , vol.6 , Issue.7 , pp. 1010-1012
    • Kostyuk, E.1    Pronchuk, N.2    Shmigol, A.3
  • 57
    • 0034780525 scopus 로고    scopus 로고
    • Diabetes-induced changes in calcium homeostasis and the effects of calcium channel blockers in rat and mice nociceptive neurons
    • Kostyuk E, Voitenko N, Kruglikov I et al. Diabetes-induced changes in calcium homeostasis and the effects of calcium channel blockers in rat and mice nociceptive neurons. Diabetologia 44(10), 1302-1309 (2001).
    • (2001) Diabetologia , vol.44 , Issue.10 , pp. 1302-1309
    • Kostyuk, E.1    Voitenko, N.2    Kruglikov, I.3
  • 58
    • 0032830323 scopus 로고    scopus 로고
    • Changes in calcium signalling in dorsal horn neurons in rats with streptozotocin-induced diabetes
    • Voitenko NV, Kostyuk EP, Kruglikov IA, Kostyuk PG. Changes in calcium signalling in dorsal horn neurons in rats with streptozotocin-induced diabetes. Neuroscience 94(3), 887-890 (1999).
    • (1999) Neuroscience , vol.94 , Issue.3 , pp. 887-890
    • Voitenko, N.V.1    Kostyuk, E.P.2    Kruglikov, I.A.3    Kostyuk, P.G.4
  • 59
    • 0032714166 scopus 로고    scopus 로고
    • Effect of streptozotocininduced diabetes on the activity of calcium channels in rat dorsal horn neurons
    • Voitenko NV, Kruglikov IA, Kostyuk EP, Kostyuk PG. Effect of streptozotocininduced diabetes on the activity of calcium channels in rat dorsal horn neurons. Neuroscience 95(2), 519-524 (2000).
    • (2000) Neuroscience , vol.95 , Issue.2 , pp. 519-524
    • Voitenko, N.V.1    Kruglikov, I.A.2    Kostyuk, E.P.3    Kostyuk, P.G.4
  • 60
    • 0032903141 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in calcium signalling alterations in dorsal root ganglion neurons of mice with experimentally-induced diabetes
    • Kostyuk E, Svichar N, Shishkin V, Kostyuk P. Role of mitochondrial dysfunction in calcium signalling alterations in dorsal root ganglion neurons of mice with experimentally-induced diabetes. Neuroscience 90(2), 535-541 (1999).
    • (1999) Neuroscience , vol.90 , Issue.2 , pp. 535-541
    • Kostyuk, E.1    Svichar, N.2    Shishkin, V.3    Kostyuk, P.4
  • 61
    • 33646365376 scopus 로고    scopus 로고
    • Effect of protein kinase Cb inhibitor on Ca2+ homeostasis in diabetic sensory neurons
    • Tahara M, Omatsu-Kanbe M, Sanada M et al. Effect of protein kinase Cb inhibitor on Ca2+ homeostasis in diabetic sensory neurons. Neuroreport 17(6), 683-688 (2006).
    • (2006) Neuroreport , vol.17 , Issue.6 , pp. 683-688
    • Tahara, M.1    Omatsu-Kanbe, M.2    Sanada, M.3
  • 62
    • 11144304094 scopus 로고    scopus 로고
    • Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats
    • Li F, Obrosova IG, Abatan O et al. Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats. Am. J. Physiol. Endocrinol. Metab. 288(1), E29-E36 (2005).
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.288 , Issue.1
    • Li, F.1    Obrosova, I.G.2    Abatan, O.3
  • 63
    • 0034307469 scopus 로고    scopus 로고
    • Stimulation-evoked increases in cytosolic [Ca2+] in mouse motor nerve terminals are limited by mitochondrial uptake and are temperaturedependent
    • David G, Barrett EF. Stimulation-evoked increases in cytosolic [Ca2+] in mouse motor nerve terminals are limited by mitochondrial uptake and are temperaturedependent. J. Neurosci. 20(19), 7290-7296 (2000).
    • (2000) J. Neurosci. , vol.20 , Issue.19 , pp. 7290-7296
    • David, G.1    Barrett, E.F.2
  • 64
    • 0032523758 scopus 로고    scopus 로고
    • Evidence that mitochondria buffer physiological Ca2+ loads in lizard motor nerve terminals
    • David G, Barrett JN, Barrett EF. Evidence that mitochondria buffer physiological Ca2+ loads in lizard motor nerve terminals. J. Physiol. 509(Pt 1), 59-65 (1998).
    • (1998) J. Physiol. , vol.509 , Issue.PART 1 , pp. 59-65
    • David, G.1    Barrett, J.N.2    Barrett, E.F.3
  • 66
    • 31544446599 scopus 로고    scopus 로고
    • Spatially organised mitochondrial calcium uptake through a novel pathway in chick neurones
    • Coatesworth W, Bolsover S. Spatially organised mitochondrial calcium uptake through a novel pathway in chick neurones. Cell Calcium 39(3), 217-225 (2006).
    • (2006) Cell Calcium , vol.39 , Issue.3 , pp. 217-225
    • Coatesworth, W.1    Bolsover, S.2
  • 67
    • 1642540210 scopus 로고    scopus 로고
    • The mitochondrial calcium uniporter is a highly selective ion channel
    • Kirichok Y, Krapivinsky G, Clapham DE. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 427(6972), 360-364 (2004).
    • (2004) Nature , vol.427 , Issue.6972 , pp. 360-364
    • Kirichok, Y.1    Krapivinsky, G.2    Clapham, D.E.3
  • 68
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls DG, Budd SL. Mitochondria and neuronal survival. Physiol. Rev. 80(1), 315-360 (2000).
    • (2000) Physiol. Rev. , vol.80 , Issue.1 , pp. 315-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 69
    • 1842430709 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures
    • Nicholls DG. Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures. Curr. Mol. Med. 4(2), 149-177 (2004).
    • (2004) Curr. Mol. Med. , vol.4 , Issue.2 , pp. 149-177
    • Nicholls, D.G.1
  • 70
    • 24644462789 scopus 로고    scopus 로고
    • Mitochondria and calcium signaling
    • Nicholls DG. Mitochondria and calcium signaling. Cell Calcium 38(3-4), 311-317 (2005).
    • (2005) Cell Calcium , vol.38 , Issue.3-4 , pp. 311-317
    • Nicholls, D.G.1
  • 73
    • 0025319665 scopus 로고
    • Role of calcium ions in regulation of mammalian intramitochondrial metabolism
    • McCormack JG, Halestrap AP, Denton RM. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70(2), 391-425 (1990).
    • (1990) Physiol. Rev. , vol.70 , Issue.2 , pp. 391-425
    • McCormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 74
    • 0035951868 scopus 로고    scopus 로고
    • Calcium activation of heart mitochondrial oxidative phosphorylation: Rapid kinetics of mVO2, NADH, and light scattering
    • Territo PR, French SA, Dunleavy MC, Evans FJ, Balaban RS. Calcium activation of heart mitochondrial oxidative phosphorylation: rapid kinetics of mVO2, NADH, AND light scattering. J. Biol. Chem. 276(4), 2586-2599 (2001).
    • (2001) J. Biol. Chem. , vol.276 , Issue.4 , pp. 2586-2599
    • Territo, P.R.1    French, S.A.2    Dunleavy, M.C.3    Evans, F.J.4    Balaban, R.S.5
  • 76
    • 1542563727 scopus 로고    scopus 로고
    • The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach
    • Perez-Campo R, Lopez-Torres M, Cadenas S, Rojas C, Barja G. The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach. J. Comp. Physiol. B 168(3), 149-158 (1998).
    • (1998) J. Comp. Physiol. B , vol.168 , Issue.3 , pp. 149-158
    • Perez-Campo, R.1    Lopez-Torres, M.2    Cadenas, S.3    Rojas, C.4    Barja, G.5
  • 77
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban RS, Nemoto S, Finkel T. Mitochondria, oxidants, and aging. Cell 120(4), 483-495 (2005).
    • (2005) Cell , vol.120 , Issue.4 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 78
    • 33748561167 scopus 로고    scopus 로고
    • Cross-talk between calcium and reactive oxygen species signaling
    • Yan Y, Wei CL, Zhang WR, Cheng HP, Liu J. Cross-talk between calcium and reactive oxygen species signaling. Acta Pharmacol. Sin. 27(7), 821-826 (2006).
    • (2006) Acta Pharmacol. Sin. , vol.27 , Issue.7 , pp. 821-826
    • Yan, Y.1    Wei, C.L.2    Zhang, W.R.3    Cheng, H.P.4    Liu, J.5
  • 79
    • 70349134016 scopus 로고    scopus 로고
    • Tissue-specific remodeling of the mitochondrial proteome in Type 1 diabetic Akita mice
    • Bugger H, Chen D, Riehle C et al. Tissue-specific remodeling of the mitochondrial proteome in Type 1 diabetic Akita mice. Diabetes 58(9), 1986-1997 (2009).
    • (2009) Diabetes , vol.58 , Issue.9 , pp. 1986-1997
    • Bugger, H.1    Chen, D.2    Riehle, C.3
  • 80
    • 0142213194 scopus 로고    scopus 로고
    • Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: A new experimental model of diabetic autonomic neuropathy
    • Schmidt RE, Dorsey DA, Beaudet LN et al. Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: a new experimental model of diabetic autonomic neuropathy. Am. J. Pathol. 163(5), 2077-2091 (2003).
    • (2003) Am. J. Pathol. , vol.163 , Issue.5 , pp. 2077-2091
    • Schmidt, R.E.1    Dorsey, D.A.2    Beaudet, L.N.3
  • 81
    • 0037631821 scopus 로고    scopus 로고
    • Analysis of the Zucker diabetic fatty (ZDF) Type 2 diabetic rat model suggests a neurotrophic role for insulin/IGF-I in diabetic autonomic neuropathy
    • Schmidt RE, Dorsey DA, Beaudet LN, Peterson RG. Analysis of the Zucker diabetic fatty (ZDF) Type 2 diabetic rat model suggests a neurotrophic role for insulin/IGF-I in diabetic autonomic neuropathy. Am. J. Pathol. 163(1), 21-28 (2003).
    • (2003) Am. J. Pathol. , vol.163 , Issue.1 , pp. 21-28
    • Schmidt, R.E.1    Dorsey, D.A.2    Beaudet, L.N.3    Peterson, R.G.4
  • 82
    • 59749096957 scopus 로고    scopus 로고
    • Neuritic dystrophy and neuronopathy in Akita (Ins2(Akita)) diabetic mouse sympathetic ganglia
    • Schmidt RE, Green KG, Snipes LL, Feng D. Neuritic dystrophy and neuronopathy in Akita (Ins2(Akita)) diabetic mouse sympathetic ganglia. Exp. Neurol. 216(1), 207-218 (2009).
    • (2009) Exp. Neurol. , vol.216 , Issue.1 , pp. 207-218
    • Schmidt, R.E.1    Green, K.G.2    Snipes, L.L.3    Feng, D.4
  • 83
    • 58149376487 scopus 로고    scopus 로고
    • Synaptic ultrastructural alterations anticipate the development of neuroaxonal dystrophy in sympathetic ganglia of aged and diabetic mice
    • Schmidt RE, Parvin CA, Green KG. Synaptic ultrastructural alterations anticipate the development of neuroaxonal dystrophy in sympathetic ganglia of aged and diabetic mice. J. Neuropathol. Exp. Neurol. 67(12), 1166-1186 (2008).
    • (2008) J. Neuropathol. Exp. Neurol. , vol.67 , Issue.12 , pp. 1166-1186
    • Schmidt, R.E.1    Parvin, C.A.2    Green, K.G.3
  • 84
    • 0027731217 scopus 로고
    • Effect of diabetes and aging on human sympathetic autonomic ganglia
    • Schmidt RE, Plurad SB, Parvin CA, Roth KA. Effect of diabetes and aging on human sympathetic autonomic ganglia. Am. J. Pathol. 143(1), 143-153 (1993).
    • (1993) Am. J. Pathol. , vol.143 , Issue.1 , pp. 143-153
    • Schmidt, R.E.1    Plurad, S.B.2    Parvin, C.A.3    Roth, K.A.4
  • 85
    • 37749043369 scopus 로고    scopus 로고
    • Mitochondrial dynamics and peripheral neuropathy
    • Baloh RH. Mitochondrial dynamics and peripheral neuropathy. Neuroscientist 14(1), 12-18 (2008).
    • (2008) Neuroscientist , vol.14 , Issue.1 , pp. 12-18
    • Baloh, R.H.1
  • 86
    • 33745274726 scopus 로고    scopus 로고
    • Mitochondria: Dynamic organelles in disease, aging, and development
    • Chan DC. Mitochondria: dynamic organelles in disease, aging, and development. Cell 125(7), 1241-1252 (2006).
    • (2006) Cell , vol.125 , Issue.7 , pp. 1241-1252
    • Chan, D.C.1
  • 87
    • 33646194845 scopus 로고    scopus 로고
    • Dysregulation of mitochondrial fusion and fission: An emerging concept in neurodegeneration
    • Frank S. Dysregulation of mitochondrial fusion and fission: an emerging concept in neurodegeneration. Acta Neuropathol. 111(2), 93-100 (2006).
    • (2006) Acta Neuropathol , vol.111 , Issue.2 , pp. 93-100
    • Frank, S.1
  • 88
    • 0043166392 scopus 로고    scopus 로고
    • Dynamics of mitochondrial morphology in healthy cells and during apoptosis
    • Karbowski M, Youle RJ. Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ. 10(8), 870-880 (2003).
    • (2003) Cell Death Differ , vol.10 , Issue.8 , pp. 870-880
    • Karbowski, M.1    Youle, R.J.2
  • 89
    • 0029948582 scopus 로고    scopus 로고
    • Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons
    • Overly CC, Rieff HI, Hollenbeck PJ. Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons. J. Cell Sci. 109(Pt 5), 971-980 (1996).
    • (1996) J. Cell Sci. , vol.109 , Issue.PART 5 , pp. 971-980
    • Overly, C.C.1    Rieff, H.I.2    Hollenbeck, P.J.3
  • 90
    • 9644290768 scopus 로고    scopus 로고
    • Mitochondrial organization and motility probed by two-photon microscopy in cultured mouse brainstem neurons
    • Muller M, Mironov SL, Ivannikov MV, Schmidt J, Richter DW. Mitochondrial organization and motility probed by two-photon microscopy in cultured mouse brainstem neurons. Exp. Cell Res. 303(1), 114-127 (2005).
    • (2005) Exp. Cell Res. , vol.303 , Issue.1 , pp. 114-127
    • Muller, M.1    Mironov, S.L.2    Ivannikov, M.V.3    Schmidt, J.4    Richter, D.W.5
  • 91
    • 33744964144 scopus 로고    scopus 로고
    • Synaptic mitochondria are more susceptible to Ca2+ overload than nonsynaptic mitochondria
    • Brown MR, Sullivan PG, Geddes JW. Synaptic mitochondria are more susceptible to Ca2+ overload than nonsynaptic mitochondria. J. Biol. Chem. 281(17), 11658-11668 (2006).
    • (2006) J. Biol. Chem. , vol.281 , Issue.17 , pp. 11658-11668
    • Brown, M.R.1    Sullivan, P.G.2    Geddes, J.W.3
  • 93
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183(5), 795-803 (2008).
    • (2008) J. Cell Biol. , vol.183 , Issue.5 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 94
    • 33748028841 scopus 로고    scopus 로고
    • Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons
    • Barsoum MJ, Yuan H, Gerencser AA et al. Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J. 25(16), 3900-3911 (2006).
    • (2006) EMBO J. , vol.25 , Issue.16 , pp. 3900-3911
    • Barsoum, M.J.1    Yuan, H.2    Gerencser, A.A.3
  • 95
    • 64249133725 scopus 로고    scopus 로고
    • S-nitrosylation of Drp1 mediates b-amyloid-related mitochondrial fission and neuronal injury
    • Cho DH, Nakamura T, Fang J et al. S-nitrosylation of Drp1 mediates b-amyloid-related mitochondrial fission and neuronal injury. Science 324(5923), 102-105 (2009).
    • (2009) Science , vol.324 , Issue.5923 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3
  • 96
    • 33846224191 scopus 로고    scopus 로고
    • Altered axonal mitochondrial transport in the pathogenesis of Charcot- Marie-Tooth disease from mitofusin 2 mutations
    • Baloh RH, Schmidt RE, Pestronk A, Milbrandt J. Altered axonal mitochondrial transport in the pathogenesis of Charcot- Marie-Tooth disease from mitofusin 2 mutations. J. Neurosci. 27(2), 422-430 (2007).
    • (2007) J. Neurosci. , vol.27 , Issue.2 , pp. 422-430
    • Baloh, R.H.1    Schmidt, R.E.2    Pestronk, A.3    Milbrandt, J.4
  • 97
    • 56749105874 scopus 로고    scopus 로고
    • Ubiquitin-dependent and -independent mitochondrial protein quality controls: Implications in ageing and neurodegenerative diseases
    • Germain D. Ubiquitin-dependent and -independent mitochondrial protein quality controls: implications in ageing and neurodegenerative diseases. Mol. Microbiol. 70(6), 1334-1341 (2008).
    • (2008) Mol. Microbiol. , vol.70 , Issue.6 , pp. 1334-1341
    • Germain, D.1
  • 98
    • 70349306718 scopus 로고    scopus 로고
    • Nitric oxide links mitochondrial fission to Alzheimers disease
    • Westermann B. Nitric oxide links mitochondrial fission to Alzheimers disease. Sci. Signal. 2(69), pe29 (2009).
    • (2009) Sci. Signal. , vol.2 , Issue.69
    • Westermann, B.1
  • 99
    • 33644552417 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
    • Yu T, Robotham JL, Yoon Y. Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc. Natl Acad. Sci. USA 103(8), 2653-2658 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.8 , pp. 2653-2658
    • Yu, T.1    Robotham, J.L.2    Yoon, Y.3
  • 100
    • 33746881744 scopus 로고    scopus 로고
    • Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1
    • Leinninger GM, Backus C, Sastry AM, Yi YB, Wang CW, Feldman EL. Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiol. Dis. 23(1), 11-22 (2006).
    • (2006) Neurobiol. Dis. , vol.23 , Issue.1 , pp. 11-22
    • Leinninger, G.M.1    Backus, C.2    Sastry, A.M.3    Yi, Y.B.4    Wang, C.W.5    Feldman, E.L.6
  • 101
    • 70349650451 scopus 로고    scopus 로고
    • Mitochondrial networking protects b cells from nutrient induced apoptosis
    • Molina AJ, Wikstrom JD, Stiles L et al. Mitochondrial networking protects b cells from nutrient induced apoptosis. Diabetes 58(10), 2303-2315 (2009).
    • (2009) Diabetes , vol.58 , Issue.10 , pp. 2303-2315
    • Molina, A.J.1    Wikstrom, J.D.2    Stiles, L.3
  • 102
    • 4644352874 scopus 로고    scopus 로고
    • Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells
    • Paltauf-Doburzynska J, Malli R, Graier WF. Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells. J. Cardiovasc. Pharmacol. 44(4), 423-436 (2004).
    • (2004) J. Cardiovasc. Pharmacol. , vol.44 , Issue.4 , pp. 423-436
    • Paltauf-Doburzynska, J.1    Malli, R.2    Graier, W.F.3
  • 103
    • 46749156297 scopus 로고    scopus 로고
    • Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
    • Yu T, Sheu SS, Robotham JL, Yoon Y. Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc. Res. 79(2), 341-351 (2008).
    • (2008) Cardiovasc. Res. , vol.79 , Issue.2 , pp. 341-351
    • Yu, T.1    Sheu, S.S.2    Robotham, J.L.3    Yoon, Y.4
  • 104
    • 57749100271 scopus 로고    scopus 로고
    • Selective actions of mitochondrial fission/ fusion genes on metabolism-secretion coupling in insulin-releasing cells
    • Park KS, Wiederkehr A, Kirkpatrick C et al. Selective actions of mitochondrial fission/ fusion genes on metabolism-secretion coupling in insulin-releasing cells. J. Biol. Chem. 283(48), 33347-33356 (2008).
    • (2008) J. Biol. Chem. , vol.283 , Issue.48 , pp. 33347-33356
    • Park, K.S.1    Wiederkehr, A.2    Kirkpatrick, C.3
  • 105
    • 0001007512 scopus 로고
    • The Crabtree effect: A review
    • Ibsen HK. The Crabtree effect: a review. Cancer Res. 21, 829-841 (1961).
    • (1961) Cancer Res , vol.21 , pp. 829-841
    • Ibsen, H.K.1
  • 106
    • 33750917609 scopus 로고    scopus 로고
    • Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats
    • Jiang Y, Calcutt NA, Ramos KM, Mizisin AP. Novel sites of aldose reductase immunolocalization in normal and streptozotocin-diabetic rats. J. Peripher. Nerv. Syst. 11(4), 274-285 (2006).
    • (2006) J. Peripher. Nerv. Syst. , vol.11 , Issue.4 , pp. 274-285
    • Jiang, Y.1    Calcutt, N.A.2    Ramos, K.M.3    Mizisin, A.P.4
  • 107
    • 0026799191 scopus 로고
    • Identification and characterization of aldose reductase in cultured rat mesangial cells
    • Kikkawa R, Umemura K, Haneda M et al. Identification and characterization of aldose reductase in cultured rat mesangial cells. Diabetes 41(9), 1165-1171 (1992).
    • (1992) Diabetes , vol.41 , Issue.9 , pp. 1165-1171
    • Kikkawa, R.1    Umemura, K.2    Haneda, M.3
  • 108
    • 0026072511 scopus 로고
    • Aldose reductase activity and myo-inositol levels in sciatic nerve and dorsal root ganglia of the diabetic mutant mouse [C57/BL/Ks (db/db)]
    • Llewelyn JG, Thomas PK, Mirrlees DJ. Aldose reductase activity and myo-inositol levels in sciatic nerve and dorsal root ganglia of the diabetic mutant mouse [C57/BL/Ks (db/db)]. Metabolism 40(10), 1084-1087 (1991).
    • (1991) Metabolism , vol.40 , Issue.10 , pp. 1084-1087
    • Llewelyn, J.G.1    Thomas, P.K.2    Mirrlees, D.J.3
  • 109
    • 0024562784 scopus 로고
    • Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induced diabetic rats
    • Schmidt RE, Plurad SB, Sherman WR, Williamson JR, Tilton RG. Effects of aldose reductase inhibitor sorbinil on neuroaxonal dystrophy and levels of myo-inositol and sorbitol in sympathetic autonomic ganglia of streptozocin-induced diabetic rats. Diabetes 38(5), 569-579 (1989).
    • (1989) Diabetes , vol.38 , Issue.5 , pp. 569-579
    • Schmidt, R.E.1    Plurad, S.B.2    Sherman, W.R.3    Williamson, J.R.4    Tilton, R.G.5
  • 110
    • 61949120326 scopus 로고    scopus 로고
    • Diabetic cardiomyopathyassociated dysfunction in spatially distinct mitochondrial subpopulations
    • Dabkowski ER, Williamson CL, Bukowski VC et al. Diabetic cardiomyopathyassociated dysfunction in spatially distinct mitochondrial subpopulations. Am. J. Physiol. Heart Circ. Physiol. 296(2), H359-H369 (2009).
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.296 , Issue.2
    • Dabkowski, E.R.1    Williamson, C.L.2    Bukowski, V.C.3
  • 111
    • 67349083630 scopus 로고    scopus 로고
    • Insulin stimulates Akt translocation to mitochondria: Implications on dysregulation of mitochondrial oxidative phosphorylation in diabetic myocardium
    • Yang JY, Yeh HY, Lin K, Wang PH. Insulin stimulates Akt translocation to mitochondria: implications on dysregulation of mitochondrial oxidative phosphorylation in diabetic myocardium. J. Mol. Cell. Cardiol. 46(6), 919-926 (2009).
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , Issue.6 , pp. 919-926
    • Yang, J.Y.1    Yeh, H.Y.2    Lin, K.3    Wang, P.H.4
  • 112
    • 33847632848 scopus 로고    scopus 로고
    • Early myocardial dysfunction in streptozotocininduced diabetic mice: A study using in vivo magnetic resonance imaging (MRI)
    • Yu X, Tesiram YA, Towner RA et al. Early myocardial dysfunction in streptozotocininduced diabetic mice: a study using in vivo magnetic resonance imaging (MRI). Cardiovasc. Diabetol. 6, 6 (2007).
    • (2007) Cardiovasc. Diabetol. , vol.6 , pp. 6
    • Yu, X.1    Tesiram, Y.A.2    Towner, R.A.3
  • 113
    • 58149458130 scopus 로고    scopus 로고
    • Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats
    • Herlein JA, Fink BD, OMalley Y, Sivitz WI. Superoxide and respiratory coupling in mitochondria of insulin-deficient diabetic rats. Endocrinology 150(1), 46-55 (2009).
    • (2009) Endocrinology , vol.150 , Issue.1 , pp. 46-55
    • Herlein, J.A.1    Fink, B.D.2    Omalley, Y.3    Sivitz, W.I.4
  • 114
    • 33644637265 scopus 로고    scopus 로고
    • Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart
    • Lashin OM, Szweda PA, Szweda LI, Romani AM. Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart. Free Radic. Biol. Med. 40(5), 886-896 (2006).
    • (2006) Free Radic. Biol. Med. , vol.40 , Issue.5 , pp. 886-896
    • Lashin, O.M.1    Szweda, P.A.2    Szweda, L.I.3    Romani, A.M.4
  • 115
    • 6044224889 scopus 로고    scopus 로고
    • Cardiac mitochondrial damage and biogenesis in a chronic model of Type 1 diabetes
    • Shen X, Zheng S, Thongboonkerd V et al. Cardiac mitochondrial damage and biogenesis in a chronic model of Type 1 diabetes. Am. J. Physiol. Endocrinol. Metab. 287(5), E896-E905 (2004).
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287 , Issue.5
    • Shen, X.1    Zheng, S.2    Thongboonkerd, V.3
  • 116
    • 58149330628 scopus 로고    scopus 로고
    • Type 1 diabetic Akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3
    • Bugger H, Boudina S, Hu XX et al. Type 1 diabetic Akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3. Diabetes 57(11), 2924-2932 (2008).
    • (2008) Diabetes , vol.57 , Issue.11 , pp. 2924-2932
    • Bugger, H.1    Boudina, S.2    Hu, X.X.3
  • 117
    • 38149090083 scopus 로고    scopus 로고
    • Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type i diabetes
    • de Cavanagh EM, Ferder L, Toblli JE et al. Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes. Am. J. Physiol. Heart Circ. Physiol. 294(1), H456-H465 (2008).
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294 , Issue.1
    • De Cavanagh, E.M.1    Ferder, L.2    Toblli, J.E.3
  • 119
    • 33847611885 scopus 로고    scopus 로고
    • Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle
    • Boushel R, Gnaiger E, Schjerling P, Skovbro M, Kraunsoe R, Dela F. Patients with Type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50(4), 790-796 (2007).
    • (2007) Diabetologia , vol.50 , Issue.4 , pp. 790-796
    • Boushel, R.1    Gnaiger, E.2    Schjerling, P.3    Skovbro, M.4    Kraunsoe, R.5    Dela, F.6
  • 120
    • 34249720640 scopus 로고    scopus 로고
    • Mitochondrial respiration is decreased in skeletal muscle of patients with Type 2 diabetes
    • Mogensen M, Sahlin K, Fernstrom M et al. Mitochondrial respiration is decreased in skeletal muscle of patients with Type 2 diabetes. Diabetes 56(6), 1592-1599 (2007).
    • (2007) Diabetes , vol.56 , Issue.6 , pp. 1592-1599
    • Mogensen, M.1    Sahlin, K.2    Fernstrom, M.3
  • 121
    • 58149346025 scopus 로고    scopus 로고
    • Lower intrinsic ADPstimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male Type 2 diabetic patients
    • Phielix E, Schrauwen-Hinderling VB, Mensink M et al. Lower intrinsic ADPstimulated mitochondrial respiration underlies in vivo mitochondrial dysfunction in muscle of male Type 2 diabetic patients. Diabetes 57(11), 2943-2949 (2008).
    • (2008) Diabetes , vol.57 , Issue.11 , pp. 2943-2949
    • Phielix, E.1    Schrauwen-Hinderling, V.B.2    Mensink, M.3
  • 122
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in Type 2 diabetes
    • Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in Type 2 diabetes. Diabetes 51(10), 2944-2950 (2002).
    • (2002) Diabetes , vol.51 , Issue.10 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 123
    • 61449147889 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species generation in obese non-diabetic and Type 2 diabetic participants
    • Abdul-Ghani MA, Jani R, Chavez A, Molina-Carrion M, Tripathy D, Defronzo RA. Mitochondrial reactive oxygen species generation in obese non-diabetic and Type 2 diabetic participants. Diabetologia 52(4), 574-582 (2009).
    • (2009) Diabetologia , vol.52 , Issue.4 , pp. 574-582
    • Abdul-Ghani, M.A.1    Jani, R.2    Chavez, A.3    Molina-Carrion, M.4    Tripathy, D.5    Defronzo, R.A.6
  • 124
    • 61549133253 scopus 로고    scopus 로고
    • Improved glycaemic control decreases inner mitochondrial membrane leak in Type 2 diabetes
    • Rabol R, Hojberg PM, Almdal T et al. Improved glycaemic control decreases inner mitochondrial membrane leak in Type 2 diabetes. Diabetes Obes. Metab. 11(4), 355-360 (2009).
    • (2009) Diabetes Obes. Metab. , vol.11 , Issue.4 , pp. 355-360
    • Rabol, R.1    Hojberg, P.M.2    Almdal, T.3
  • 125
    • 65249175787 scopus 로고    scopus 로고
    • Effect of hyperglycemia on mitochondrial respiration in Type 2 diabetes
    • Rabol R, Hojberg PM, Almdal T et al. Effect of hyperglycemia on mitochondrial respiration in Type 2 diabetes. J. Clin. Endocrinol. Metab. 94(4), 1372-1378 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , Issue.4 , pp. 1372-1378
    • Rabol, R.1    Hojberg, P.M.2    Almdal, T.3
  • 126
    • 67651123214 scopus 로고    scopus 로고
    • Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
    • Rabol R, Svendsen PF, Skovbro M et al. Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss. Metabolism 58, 1145-1152 (2009).
    • (2009) Metabolism , vol.58 , pp. 1145-1152
    • Rabol, R.1    Svendsen, P.F.2    Skovbro, M.3
  • 127
    • 48449104125 scopus 로고    scopus 로고
    • A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of Type 2 diabetic Goto-Kakizaki rats
    • Shen W, Hao J, Tian C et al. A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of Type 2 diabetic Goto-Kakizaki rats. PLoS ONE 3(6), e2328 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.6
    • Shen, W.1    Hao, J.2    Tian, C.3
  • 128
    • 55549110913 scopus 로고    scopus 로고
    • Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of Type 2 diabetes
    • De Feyter HM, Lenaers E, Houten SM et al. Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of Type 2 diabetes. FASEB J. 22(11), 3947-3955 (2008).
    • (2008) FASEB J. , vol.22 , Issue.11 , pp. 3947-3955
    • De Feyter, H.M.1    Lenaers, E.2    Houten, S.M.3
  • 129
    • 21344442593 scopus 로고    scopus 로고
    • High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphatedependent ROS production in prostate cancer cell lines
    • Chowdhury SK, Gemin A, Singh G. High activity of mitochondrial glycerophosphate dehydrogenase and glycerophosphatedependent ROS production in prostate cancer cell lines. Biochem. Biophys. Res. Commun. 333(4), 1139-1145 (2005).
    • (2005) Biochem. Biophys. Res. Commun. , vol.333 , Issue.4 , pp. 1139-1145
    • Chowdhury, S.K.1    Gemin, A.2    Singh, G.3
  • 130
    • 34250323884 scopus 로고    scopus 로고
    • Normal platelet mitochondrial complex i activity in Huntingtons disease
    • Powers WJ, Haas RH, Le T et al. Normal platelet mitochondrial complex I activity in Huntingtons disease. Neurobiol. Dis. 27(1), 99-101 (2007).
    • (2007) Neurobiol. Dis. , vol.27 , Issue.1 , pp. 99-101
    • Powers, W.J.1    Haas, R.H.2    Le, T.3
  • 131
    • 34748881883 scopus 로고    scopus 로고
    • Increased expression of mitochondrial glycerophosphate dehydrogenase and antioxidant enzymes in prostate cancer cell lines/cancer
    • Chowdhury SK, Raha S, Tarnopolsky MA, Singh G. Increased expression of mitochondrial glycerophosphate dehydrogenase and antioxidant enzymes in prostate cancer cell lines/cancer. Free Radic. Res. 41(10), 1116-1124 (2007).
    • (2007) Free Radic. Res. , vol.41 , Issue.10 , pp. 1116-1124
    • Chowdhury, S.K.1    Raha, S.2    Tarnopolsky, M.A.3    Singh, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.