메뉴 건너뛰기




Volumn 5, Issue 2, 2014, Pages

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice

Author keywords

aging; Alzheimer's disease; inflammation; microarray; mitochondria; synaptic plasticity

Indexed keywords

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; APP GENE; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; DOWN REGULATION; GENE; GENE CLUSTER; GENE EXPRESSION; GENE MUTATION; HIPPOCAMPUS; HOMEOSTASIS; INFLAMMATION; MEMORY; MOUSE; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PS1 GENE; TAU GENE; UPREGULATION;

EID: 84896798747     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.11     Document Type: Article
Times cited : (39)

References (62)
  • 2
    • 84871922036 scopus 로고    scopus 로고
    • Deciphering the mechanism underlying late-onset Alzheimer disease
    • Krstic D, Knuesel I. Deciphering the mechanism underlying late-onset Alzheimer disease. Nat Rev Neurol 2013; 9: 25-34.
    • (2013) Nat Rev Neurol , vol.9 , pp. 25-34
    • Krstic, D.1    Knuesel, I.2
  • 3
    • 78650403081 scopus 로고    scopus 로고
    • Reimagining Alzheimer's disease-An age-based hypothesis
    • Herrup K. Reimagining Alzheimer's disease-An age-based hypothesis. J Neurosci 2010 16755-16762.
    • (2010) J Neurosci , pp. 16755-16762
    • Herrup, K.1
  • 5
    • 33744925947 scopus 로고    scopus 로고
    • Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models
    • Reddy PH, McWeeney S. Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models. Neurobiol Aging 2006; 27: 1060-1077.
    • (2006) Neurobiol Aging , vol.27 , pp. 1060-1077
    • Reddy, P.H.1    McWeeney, S.2
  • 6
    • 0042697305 scopus 로고    scopus 로고
    • Triple-Transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
    • Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R et al. Triple-Transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction. Neuron 2003; 39: 409-421.
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5    Kayed, R.6
  • 7
    • 79960017316 scopus 로고    scopus 로고
    • New therapeutic targets in Alzheimer's disease: Brain deregulation of calcium and zinc
    • Corona C, Pensalfini A, Frazzini V, Sensi SL. New therapeutic targets in Alzheimer's disease: Brain deregulation of calcium and zinc. Cell Death Dis 2011; 2: E176.
    • (2011) Cell Death Dis , vol.2
    • Corona, C.1    Pensalfini, A.2    Frazzini, V.3    Sensi, S.L.4
  • 8
    • 5344261151 scopus 로고    scopus 로고
    • Calcium extrusion protein expression in the hippocampal formation of chronic epileptic rats after kainate-induced status epilepticus
    • Ketelaars SO, Gorter JA, Aronica E, Wadman WJ. Calcium extrusion protein expression in the hippocampal formation of chronic epileptic rats after kainate-induced status epilepticus. Epilepsia 2004; 45: 1189-1201.
    • (2004) Epilepsia , vol.45 , pp. 1189-1201
    • Ketelaars, S.O.1    Gorter, J.A.2    Aronica, E.3    Wadman, W.J.4
  • 9
    • 0034957735 scopus 로고    scopus 로고
    • Microarray analysis of hippocampal gene expression in global cerebral ischemia
    • Jin K, Mao XO, Eshoo MW, Nagayama T, Minami M, Simon RP et al. Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann Neurol 2001; 50: 93-103.
    • (2001) Ann Neurol , vol.50 , pp. 93-103
    • Jin, K.1    Mao, X.O.2    Eshoo, M.W.3    Nagayama, T.4    Minami, M.5    Simon, R.P.6
  • 10
    • 84862261275 scopus 로고    scopus 로고
    • Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice
    • Chakroborty S, Kim J, Schneider C, Jacobson C, Molgo J, Stutzmann GE. Early presynaptic and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice. J Neurosci 2012; 32: 8341-8353.
    • (2012) J Neurosci , vol.32 , pp. 8341-8353
    • Chakroborty, S.1    Kim, J.2    Schneider, C.3    Jacobson, C.4    Molgo, J.5    Stutzmann, G.E.6
  • 11
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006; 443: 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 12
    • 17744376804 scopus 로고    scopus 로고
    • GDAP1, the protein causing Charcot-Marie-Tooth disease type 4A, is expressed in neurons and is associated with mitochondria
    • Pedrola L, Espert A, Wu X, Claramunt R, Shy ME, Palau F. GDAP1, the protein causing Charcot-Marie-Tooth disease type 4A, is expressed in neurons and is associated with mitochondria. Hum Mol Genet 2005; 14: 1087-1094.
    • (2005) Hum Mol Genet , vol.14 , pp. 1087-1094
    • Pedrola, L.1    Espert, A.2    Wu, X.3    Claramunt, R.4    Shy, M.E.5    Palau, F.6
  • 13
    • 79955880517 scopus 로고    scopus 로고
    • 3,4,5-Tri-O-caffeoylquinic acid inhibits amyloid beta-mediated cellular toxicity on SH-SY5Y cells through the upregulation of PGAM1 and G3PDH
    • Miyamae Y, Han J, Sasaki K, Terakawa M, Isoda H, Shigemori H. 3,4,5-Tri-O-caffeoylquinic acid inhibits amyloid beta-mediated cellular toxicity on SH-SY5Y cells through the upregulation of PGAM1 and G3PDH. Cytotechnology 2011; 63: 191-200.
    • (2011) Cytotechnology , vol.63 , pp. 191-200
    • Miyamae, Y.1    Han, J.2    Sasaki, K.3    Terakawa, M.4    Isoda, H.5    Shigemori, H.6
  • 14
    • 79955972587 scopus 로고    scopus 로고
    • Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons
    • Brickley K, Stephenson FA. Trafficking kinesin protein (TRAK)-mediated transport of mitochondria in axons of hippocampal neurons. J Biol Chem 2011; 286: 18079-18092.
    • (2011) J Biol Chem , vol.286 , pp. 18079-18092
    • Brickley, K.1    Stephenson, F.A.2
  • 15
    • 84867268620 scopus 로고    scopus 로고
    • Mitochondrial division prevents neurodegeneration
    • Zhang Z, Kageyama Y, Sesaki H. Mitochondrial division prevents neurodegeneration. Autophagy 2012; 8: 1531-1533.
    • (2012) Autophagy , vol.8 , pp. 1531-1533
    • Zhang, Z.1    Kageyama, Y.2    Sesaki, H.3
  • 16
    • 77549083704 scopus 로고    scopus 로고
    • Neuroinflammation and cognitive aging
    • Ownby RL. Neuroinflammation and cognitive aging. Curr Psychiatry Rep 2010; 12: 39-45.
    • (2010) Curr Psychiatry Rep , vol.12 , pp. 39-45
    • Ownby, R.L.1
  • 17
    • 84873087532 scopus 로고    scopus 로고
    • NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
    • Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A et al. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature 2013; 493: 674-678.
    • (2013) Nature , vol.493 , pp. 674-678
    • Heneka, M.T.1    Kummer, M.P.2    Stutz, A.3    Delekate, A.4    Schwartz, S.5    Vieira-Saecker, A.6
  • 19
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002; 298: 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 20
    • 70449368211 scopus 로고    scopus 로고
    • X11beta rescues memory and long-Term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice
    • Mitchell JC, Ariff BB, Yates DM, Lau KF, Perkinton MS, Rogelj B et al. X11beta rescues memory and long-Term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice. Hum Mol Genet 2009; 18: 4492-4500.
    • (2009) Hum Mol Genet , vol.18 , pp. 4492-4500
    • Mitchell, J.C.1    Ariff, B.B.2    Yates, D.M.3    Lau, K.F.4    Perkinton, M.S.5    Rogelj, B.6
  • 21
    • 84864015486 scopus 로고    scopus 로고
    • Cystatin C in Alzheimer's disease
    • Kaur G, Levy E. Cystatin C in Alzheimer's disease. Front Mol Neurosci 2012; 5: 79.
    • (2012) Front Mol Neurosci , vol.5 , pp. 79
    • Kaur, G.1    Levy, E.2
  • 22
    • 84866114235 scopus 로고    scopus 로고
    • Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging
    • Haberman RP, Quigley CK, Gallagher M. Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging. Epigenetics 2012; 7 1019.
    • (2012) Epigenetics , vol.7 , pp. 1019
    • Haberman, R.P.1    Quigley, C.K.2    Gallagher, M.3
  • 23
    • 34250304714 scopus 로고    scopus 로고
    • Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling
    • Nizzari M, Venezia V, Repetto E, Caorsi V, Magrassi R, Gagliani MC et al. Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling. J Biol Chem 2007; 282: 13833-13844.
    • (2007) J Biol Chem , vol.282 , pp. 13833-13844
    • Nizzari, M.1    Venezia, V.2    Repetto, E.3    Caorsi, V.4    Magrassi, R.5    Gagliani, M.C.6
  • 24
    • 43049118551 scopus 로고    scopus 로고
    • Differential activation of mitogen-Activated protein kinase signalling pathways in the hippocampus of CRND8 transgenic mouse, a model of Alzheimer's disease
    • Giovannini MG, Cerbai F, Bellucci A, Melani C, Grossi C, Bartolozzi C et al. Differential activation of mitogen-Activated protein kinase signalling pathways in the hippocampus of CRND8 transgenic mouse, a model of Alzheimer's disease. Neuroscience 2008; 153 633.
    • (2008) Neuroscience , vol.153 , pp. 633
    • Giovannini, M.G.1    Cerbai, F.2    Bellucci, A.3    Melani, C.4    Grossi, C.5    Bartolozzi, C.6
  • 25
    • 33745985711 scopus 로고    scopus 로고
    • ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures
    • Chong YH, Shin YJ, Lee EO, Kayed R, Glabe CG, Tenner AJ. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. J Biol Chem 2006; 281: 20315-20325.
    • (2006) J Biol Chem , vol.281 , pp. 20315-20325
    • Chong, Y.H.1    Shin, Y.J.2    Lee, E.O.3    Kayed, R.4    Glabe, C.G.5    Tenner, A.J.6
  • 26
    • 0036159565 scopus 로고    scopus 로고
    • Decreased expression of hippocampal cholinergic neurostimulating peptide precursor protein mRNA in the hippocampus in Alzheimer disease
    • Maki M, Matsukawa N, Yuasa H, Otsuka Y, Yamamoto T, Akatsu H et al. Decreased expression of hippocampal cholinergic neurostimulating peptide precursor protein mRNA in the hippocampus in Alzheimer disease. J Neuropathol Exp Neurol 2002; 61: 176-185.
    • (2002) J Neuropathol Exp Neurol , vol.61 , pp. 176-185
    • Maki, M.1    Matsukawa, N.2    Yuasa, H.3    Otsuka, Y.4    Yamamoto, T.5    Akatsu, H.6
  • 27
    • 84865332357 scopus 로고    scopus 로고
    • The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina
    • Landgraf I, Muhlhans J, Dedek K, Reim K, Brandstatter JH, Ammermuller J. The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina. Eur J Neurosci 2012; 36: 2470-2481.
    • (2012) Eur J Neurosci , vol.36 , pp. 2470-2481
    • Landgraf, I.1    Muhlhans, J.2    Dedek, K.3    Reim, K.4    Brandstatter, J.H.5    Ammermuller, J.6
  • 29
    • 59649118111 scopus 로고    scopus 로고
    • Enhanced NMDA receptormediated synaptic transmission, enhanced long-Term potentiation, and impaired learning and memory in mice lacking IRSp53
    • Kim MH, Choi J, Yang J, Chung W, Kim JH, Paik SK et al. Enhanced NMDA receptormediated synaptic transmission, enhanced long-Term potentiation, and impaired learning and memory in mice lacking IRSp53. J Neurosci 2009; 29: 1586-1595.
    • (2009) J Neurosci , vol.29 , pp. 1586-1595
    • Kim, M.H.1    Choi, J.2    Yang, J.3    Chung, W.4    Kim, J.H.5    Paik, S.K.6
  • 30
    • 79952638895 scopus 로고    scopus 로고
    • Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction
    • Corona C, Masciopinto F, Silvestri E, Viscovo AD, Lattanzio R, Sorda RL et al. Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction. Cell Death Dis 2010; 1: E91.
    • (2010) Cell Death Dis , vol.1
    • Corona, C.1    Masciopinto, F.2    Silvestri, E.3    Viscovo, A.D.4    Lattanzio, R.5    Sorda, R.L.6
  • 31
    • 84860388355 scopus 로고    scopus 로고
    • EphBs: An integral link between synaptic function and synaptopathies
    • Sheffler-Collins SI, Dalva MB. EphBs: An integral link between synaptic function and synaptopathies. Trends Neurosci 2012; 35: 293-304.
    • (2012) Trends Neurosci , vol.35 , pp. 293-304
    • Sheffler-Collins, S.I.1    Dalva, M.B.2
  • 32
    • 0037362720 scopus 로고    scopus 로고
    • Role of kallikrein enzymes in the central nervous system
    • Yousef GM, Kishi T, Diamandis EP. Role of kallikrein enzymes in the central nervous system. Clin Chim Acta 2003; 329: 1-8.
    • (2003) Clin Chim Acta , vol.329 , pp. 1-8
    • Yousef, G.M.1    Kishi, T.2    Diamandis, E.P.3
  • 33
    • 77958516116 scopus 로고    scopus 로고
    • Effects of S100B on serotonergic plasticity and neuroinflammation in the hippocampus in Down syndrome and Alzheimer's disease: Studies in an S100B overexpressing mouse model
    • Shapiro LA, Bialowas-McGoey LA,Whitaker-Azmitia PM. Effects of S100B on serotonergic plasticity and neuroinflammation in the hippocampus in Down syndrome and Alzheimer's disease: Studies in an S100B overexpressing mouse model. Cardiovasc Psychiatry Neurol 2010; 2010: 1-13.
    • (2010) Cardiovasc Psychiatry Neurol , vol.2010 , pp. 1-13
    • Shapiro, L.A.1    Bialowas-McGoey, L.A.2    Whitaker-Azmitia, P.M.3
  • 34
    • 0036592637 scopus 로고    scopus 로고
    • Cell cycle proteins in Alzheimer's disease: Plenty of wheels but no cycle
    • Bowser R, Smith MA. Cell cycle proteins in Alzheimer's disease: Plenty of wheels but no cycle. J Alzheimers Dis 2002; 4: 249-254.
    • (2002) J Alzheimers Dis , vol.4 , pp. 249-254
    • Bowser, R.1    Smith, M.A.2
  • 35
    • 84863890450 scopus 로고    scopus 로고
    • Autophagy and neuronal cell death in neurological disorders
    • Nixon RA, Yang DS. Autophagy and neuronal cell death in neurological disorders. Cold Spring Harb Perspect Biol 2012; 4: 10.
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 10
    • Nixon, R.A.1    Yang, D.S.2
  • 36
    • 78649446153 scopus 로고    scopus 로고
    • Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease
    • Gomez Ravetti M, Rosso OA, Berretta R, Moscato P. Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease. PLoS One 2010; 5: E10153.
    • (2010) PLoS One , vol.5
    • Gomez Ravetti, M.1    Rosso, O.A.2    Berretta, R.3    Moscato, P.4
  • 37
    • 79958003204 scopus 로고    scopus 로고
    • Early growth response 1 (Egr-1) regulates phosphorylation of microtubule-Associated protein tau in mammalian brain
    • Lu Y, Li T, Qureshi HY, Han D, Paudel HK. Early growth response 1 (Egr-1) regulates phosphorylation of microtubule-Associated protein tau in mammalian brain. J Biol Chem 2011; 286: 20569-20581.
    • (2011) J Biol Chem , vol.286 , pp. 20569-20581
    • Lu, Y.1    Li, T.2    Qureshi, H.Y.3    Han, D.4    Paudel, H.K.5
  • 38
    • 40849083563 scopus 로고    scopus 로고
    • Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis
    • Yuan H, Zhang P, Qin L, Chen L, Shi S, Lu Y et al. Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis. Gene 2008; 410: 67-74.
    • (2008) Gene , vol.410 , pp. 67-74
    • Yuan, H.1    Zhang, P.2    Qin, L.3    Chen, L.4    Shi, S.5    Lu, Y.6
  • 40
    • 64049090625 scopus 로고    scopus 로고
    • Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging
    • Vakhrusheva O, Braeuer D, Liu Z, Braun T, Bober E. Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging. J Physiol Pharmacol 2008; 59(Suppl 9): 201-212.
    • (2008) J Physiol Pharmacol , vol.59 , Issue.SUPPL.9 , pp. 201-212
    • Vakhrusheva, O.1    Braeuer, D.2    Liu, Z.3    Braun, T.4    Bober, E.5
  • 41
    • 80053243942 scopus 로고    scopus 로고
    • Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
    • Majumder S, Richardson A, Strong R, Oddo S. Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One 2011; 6: E25416.
    • (2011) PLoS One , vol.6
    • Majumder, S.1    Richardson, A.2    Strong, R.3    Oddo, S.4
  • 42
    • 79956048660 scopus 로고    scopus 로고
    • Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models
    • Khandelwal PJ, Herman AM, Hoe HS, Rebeck GW, Moussa CE. Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Hum Mol Genet 2011; 20: 2091-2102.
    • (2011) Hum Mol Genet , vol.20 , pp. 2091-2102
    • Khandelwal, P.J.1    Herman, A.M.2    Hoe, H.S.3    Rebeck, G.W.4    Moussa, C.E.5
  • 43
    • 79956324801 scopus 로고    scopus 로고
    • Age-related autophagy alterations in the brain of senescence accelerated mouse prone 8 (SAMP8) mice
    • Ma Q, Qiang J, Gu P, Wang Y, Geng Y, Wang M. Age-related autophagy alterations in the brain of senescence accelerated mouse prone 8 (SAMP8) mice. Exp Gerontol 2011; 46 541.
    • (2011) Exp Gerontol , vol.46 , pp. 541
    • Ma, Q.1    Qiang, J.2    Gu, P.3    Wang, Y.4    Geng, Y.5    Wang, M.6
  • 45
    • 26444587508 scopus 로고    scopus 로고
    • Macroautophagy-A novel Beta-Amyloid peptide-generating pathway activated in Alzheimer's disease
    • Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH et al. Macroautophagy-A novel Beta-Amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol 2005; 171: 87-98.
    • (2005) J Cell Biol , vol.171 , pp. 87-98
    • Yu, W.H.1    Cuervo, A.M.2    Kumar, A.3    Peterhoff, C.M.4    Schmidt, S.D.5    Lee, J.H.6
  • 46
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 48
    • 0032522911 scopus 로고    scopus 로고
    • Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain
    • Busser J, Geldmacher DS, Herrup K. Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J Neurosci 1998; 18 2807.
    • (1998) J Neurosci , vol.18 , pp. 2807
    • Busser, J.1    Geldmacher, D.S.2    Herrup, K.3
  • 49
    • 77953089198 scopus 로고    scopus 로고
    • Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome
    • VanGuilder HD, Yan H, Farley JA, Sonntag WE, Freeman WM. Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome. J Neurochem 2010; 113: 1577-1588.
    • (2010) J Neurochem , vol.113 , pp. 1577-1588
    • VanGuilder, H.D.1    Yan, H.2    Farley, J.A.3    Sonntag, W.E.4    Freeman, W.M.5
  • 50
    • 84862560975 scopus 로고    scopus 로고
    • Loss of functional GABA(A) receptors in the Alzheimer diseased brain
    • Limon A, Reyes-Ruiz JM, Miledi R. Loss of functional GABA(A) receptors in the Alzheimer diseased brain. Proc Natl Acad Sci USA 2012; 109: 10071-10076.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 10071-10076
    • Limon, A.1    Reyes-Ruiz, J.M.2    Miledi, R.3
  • 51
    • 79953177508 scopus 로고    scopus 로고
    • N-cadherin regulates p38 MAPK signaling via association with JNK-Associated leucine zipper protein: Implications for neurodegeneration in Alzheimer disease
    • Ando K, Uemura K, Kuzuya A, Maesako M, Asada-Utsugi M, Kubota M et al. N-cadherin regulates p38 MAPK signaling via association with JNK-Associated leucine zipper protein: Implications for neurodegeneration in Alzheimer disease. J Biol Chem 2011; 286 7628.
    • (2011) J Biol Chem , vol.286 , pp. 7628
    • Ando, K.1    Uemura, K.2    Kuzuya, A.3    Maesako, M.4    Asada-Utsugi, M.5    Kubota, M.6
  • 52
    • 66149180800 scopus 로고    scopus 로고
    • The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors
    • Nadif Kasri N, Nakano-Kobayashi A, Malinow R, Li B, Van Aelst L. The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes Dev 2009; 23: 1289-1302.
    • (2009) Genes Dev , vol.23 , pp. 1289-1302
    • Nadif Kasri, N.1    Nakano-Kobayashi, A.2    Malinow, R.3    Li, B.4    Van Aelst, L.5
  • 53
    • 19944433966 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases
    • Choi J, Ko J, Racz B, Burette A, Lee JR, Kim S et al. Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases. J Neurosci 2005; 25: 869-879.
    • (2005) J Neurosci , vol.25 , pp. 869-879
    • Choi, J.1    Ko, J.2    Racz, B.3    Burette, A.4    Lee, J.R.5    Kim, S.6
  • 55
    • 75849133906 scopus 로고    scopus 로고
    • Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease
    • Mori T, Koyama N, Arendash GW, Horikoshi-Sakuraba Y, Tan J, Town T. Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease. Glia 2010; 58: 300-314.
    • (2010) Glia , vol.58 , pp. 300-314
    • Mori, T.1    Koyama, N.2    Arendash, G.W.3    Horikoshi-Sakuraba, Y.4    Tan, J.5    Town, T.6
  • 56
    • 62149151394 scopus 로고    scopus 로고
    • Vitamin E increases S100B-mediated microglial activation in an S100B-overexpressing mouse model of pathological aging
    • Bialowas-McGoey LA, Lesicka A, Whitaker-Azmitia PM. Vitamin E increases S100B-mediated microglial activation in an S100B-overexpressing mouse model of pathological aging. Glia 2008; 56: 1780-1790.
    • (2008) Glia , vol.56 , pp. 1780-1790
    • Bialowas-McGoey, L.A.1    Lesicka, A.2    Whitaker-Azmitia, P.M.3
  • 57
    • 84857194696 scopus 로고    scopus 로고
    • The S100B protein in biological fluids: More than a lifelong biomarker of brain distress
    • Michetti F, Corvino V, Geloso MC, Lattanzi W, Bernardini C, Serpero L et al. The S100B protein in biological fluids: More than a lifelong biomarker of brain distress. J Neurochem 2012; 120: 644-659.
    • (2012) J Neurochem , vol.120 , pp. 644-659
    • Michetti, F.1    Corvino, V.2    Geloso, M.C.3    Lattanzi, W.4    Bernardini, C.5    Serpero, L.6
  • 60
  • 61
    • 79959985842 scopus 로고    scopus 로고
    • Age-related changes in gene expression are accelerated in Alzheimer's disease
    • Saetre P, Jazin E, Emilsson L. Age-related changes in gene expression are accelerated in Alzheimer's disease. Synapse 2011; 65: 971-974.
    • (2011) Synapse , vol.65 , pp. 971-974
    • Saetre, P.1    Jazin, E.2    Emilsson, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.