Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs

Molecular Microbiology

Volumn 91, Issue 5, 2014, Pages 918-934

  Mok, Sachel ^a   Liong, Kek Yee ^a   Lim, Eng How ^a   Huang, Ximei ^a   Zhu, Lei ^a   Preiser, Peter Rainer ^a   Bozdech, Zbynek ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; ARTEMISININ; BENFLUMETOL; CHLOROQUINE; MEFLOQUINE; MULTIDRUG RESISTANCE PROTEIN 2; PYRIMETHAMINE; QUININE; QUINOLINE DERIVATIVE;

5' UNTRANSLATED REGION; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ERYTHROCYTE; GENE DELETION; GENE EXPRESSION REGULATION; GENE STRUCTURE; HOST PARASITE INTERACTION; MOLECULAR CLONING; NONHUMAN; PARASITE DEVELOPMENT; PFMRP2 GENE; PHENOTYPE; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; SCHIZONT; TRANSCRIPTION REGULATION; TROPHOZOITE;

PLASMODIUM FALCIPARUM;

ANTIMALARIALS; BASE PAIRING; BASE SEQUENCE; CLONE CELLS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENOME, PROTOZOAN; INTRACELLULAR SPACE; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT; PROTOZOAN PROTEINS; QUINOLINES; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84896738456     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12505     Document Type: Article

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