Novel polymorphisms in plasmodium falciparum ABC transporter genes are associated with major ACT Antimalarial drug resistance

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Veiga, Maria Isabel ^a,b   Ferreira, Pedro Eduardo ^a,b   Jörnhagen, Louise ^a   Malmberg, Maja ^a   Kone, Aminatou ^a   Schmidt, Berit Aydin ^a   Petzold, Max ^c   Björkman, Anders ^a   Nosten, Francois ^d,e,f   Gil, Jose Pedro ^a,b,g  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF ALGARVE   (Portugal)

^c NORDIC SCHOOL OF PUBLIC HEALTH   (Sweden)

^d SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^e MAHIDOL UNIVERSITY   (Thailand)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; BENFLUMETOL; DIHYDROARTEMISININ; ISOLEUCINE; MEFLOQUINE; PHENYLALANINE; TYROSINE; ABC TRANSPORTER; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; CARRIER PROTEIN; ETHANOLAMINE DERIVATIVE; FLUORENE DERIVATIVE; MDR GENE PROTEIN, PLASMODIUM; MDR1 PROTEIN, PLASMODIUM FALCIPARUM; MULTIDRUG RESISTANCE PROTEIN; PFCRT PROTEIN, PLASMODIUM FALCIPARUM; PROTOZOAL PROTEIN;

ABC TRANSPORTER GENE; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CONTROLLED STUDY; GENE; GENE SEQUENCE; GENETIC ASSOCIATION; IN VITRO STUDY; NONHUMAN; PARASITE ISOLATION; PFCRT GENE; PFMDR1 GENE; PFMRP1 GENE; PLASMODIUM FALCIPARUM; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; DRUG EFFECT; DRUG RESISTANCE; GENE FREQUENCY; GENETICS; GENOTYPE; HAPLOTYPE; HUMAN; IC 50; MALARIA FALCIPARUM; NUCLEOTIDE SEQUENCE; PARASITOLOGY;

PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; ARTEMISININS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; DRUG RESISTANCE; ETHANOLAMINES; FLUORENES; GENE FREQUENCY; GENOTYPE; HAPLOTYPES; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; MEFLOQUINE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTOZOAN PROTEINS;

EID: 79957470784     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020212     Document Type: Article

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