A common mechanism for blockade of heme polymerization by antimalarial quinolines

Journal of Biological Chemistry

Volumn 273, Issue 47, 1998, Pages 31103-31107

  Sullivan Jr , David J ^a   Matile, Hugues ^b   Ridley, Robert G ^b   Goldberg, Daniel E ^c  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; HEME; MEFLOQUINE; PROTEINASE INHIBITOR; QUINIDINE; QUINOLINE DERIVATIVE; RO 40 4388; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONCENTRATION RESPONSE; DEPOLYMERIZATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; NONHUMAN; PLASMODIUM FALCIPARUM; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; ERYTHROCYTES; HEME; HEMEPROTEINS; MEFLOQUINE; PLASMODIUM FALCIPARUM; POLYMERS; QUINIDINE; QUINOLINES;

PLASMODIUM FALCIPARUM;

EID: 1542745991     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.47.31103     Document Type: Article

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