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Volumn 19, Issue 4, 2014, Pages 603-614

Coenzyme Q10 ameliorates oxidative stress and prevents mitochondrial alteration in ischemic retinal injury

Author keywords

Coenzyme Q10; Mitochondrial DNA; Mitochondrial transcription factor A; Oxidative stress; Retinal ganglion cell; Retinal ischemia

Indexed keywords

ANTIOXIDANT; CASPASE 3; HEME OXYGENASE 1; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PROTEIN BAD; PROTEIN BAX; UBIDECARENONE; BAD PROTEIN, MOUSE; BAX PROTEIN, MOUSE; DNA BINDING PROTEIN; HIGH MOBILITY GROUP PROTEIN; NEUROPROTECTIVE AGENT; TFAM PROTEIN, MOUSE; UBIQUINONE; VITAMIN;

EID: 84896404795     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0956-x     Document Type: Article
Times cited : (70)

References (70)
  • 1
    • 2442643730 scopus 로고    scopus 로고
    • Primary open-angle glaucoma
    • 15158634 10.1016/S0140-6736(04)16257-0
    • Weinreb RN, Khaw PT (2004) Primary open-angle glaucoma. Lancet 363:1711-1720
    • (2004) Lancet , vol.363 , pp. 1711-1720
    • Weinreb, R.N.1    Khaw, P.T.2
  • 2
    • 58149330396 scopus 로고    scopus 로고
    • Glutamate receptor activation triggers OPA1 release and induces apoptotic cell death in ischemic rat retina
    • 1:CAS:528:DC%2BD1MXnslKntQ%3D%3D 2613079 19122832
    • Ju WK, Lindsey JD, Angert M, Patel A, Weinreb RN (2008) Glutamate receptor activation triggers OPA1 release and induces apoptotic cell death in ischemic rat retina. Mol Vis 14:2629-2638
    • (2008) Mol Vis , vol.14 , pp. 2629-2638
    • Ju, W.K.1    Lindsey, J.D.2    Angert, M.3    Patel, A.4    Weinreb, R.N.5
  • 3
    • 79956048283 scopus 로고    scopus 로고
    • A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina
    • 1:CAS:528:DC%2BC3MXmslSqt7o%3D 3088566 21372007 10.1167/iovs.09-5010
    • Park SW, Kim KY, Lindsey JD, Heo H, Nguyen DH, Ellisman MH et al (2011) A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest Ophthalmol Vis Sci 52:2837-2843
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 2837-2843
    • Park, S.W.1    Kim, K.Y.2    Lindsey, J.D.3    Heo, H.4    Nguyen, D.H.5    Ellisman, M.H.6
  • 5
    • 84867295552 scopus 로고    scopus 로고
    • Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury
    • 1:CAS:528:DC%2BC38XhsFKjt77I 3467218 23056591 10.1371/journal.pone. 0047098
    • Lee D, Kim KY, Noh YH, Chai S, Lindsey JD, Ellisman MH et al (2012) Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury. PLoS One 7:e47098
    • (2012) PLoS One , vol.7 , pp. 47098
    • Lee, D.1    Kim, K.Y.2    Noh, Y.H.3    Chai, S.4    Lindsey, J.D.5    Ellisman, M.H.6
  • 6
    • 35748975164 scopus 로고    scopus 로고
    • Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage
    • 17898281 10.1167/iovs.07-0170
    • Liu Q, Ju WK, Crowston JG, Xie F, Perry G, Smith MA et al (2007) Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest Ophthalmol Vis Sci 48:4580-4589
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 4580-4589
    • Liu, Q.1    Ju, W.K.2    Crowston, J.G.3    Xie, F.4    Perry, G.5    Smith, M.A.6
  • 7
    • 79960323487 scopus 로고    scopus 로고
    • Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury
    • 1:CAS:528:DC%2BC3MXpvFCjsrk%3D 21332926 10.1111/j.1474-9726.2011.00690.x
    • Kong YX, Van Bergen N, Trounce IA, Bui BV, Chrysostomou V, Waugh H et al (2011) Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury. Aging Cell 10:572-583
    • (2011) Aging Cell , vol.10 , pp. 572-583
    • Kong, Y.X.1    Van Bergen, N.2    Trounce, I.A.3    Bui, B.V.4    Chrysostomou, V.5    Waugh, H.6
  • 8
    • 0029076305 scopus 로고
    • Ontogeny of copper-zinc and manganese superoxide dismutase in the developing rat retina: Immunohistochemical and immunochemical study
    • 1:CAS:528:DyaK2MXptlaltr0%3D 8539003 10.1159/000267710
    • Oguni M, Tanaka O, Tamura H, Shinohara H, Kato K, Setogawa T (1995) Ontogeny of copper-zinc and manganese superoxide dismutase in the developing rat retina: immunohistochemical and immunochemical study. Ophthalmic Res 27:227-233
    • (1995) Ophthalmic Res , vol.27 , pp. 227-233
    • Oguni, M.1    Tanaka, O.2    Tamura, H.3    Shinohara, H.4    Kato, K.5    Setogawa, T.6
  • 9
    • 76049085234 scopus 로고    scopus 로고
    • Mitochondrial superoxide dismutase SOD2, but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells
    • 1:CAS:528:DC%2BC3cXitVKmsLc%3D 2861908 20060889 10.1016/j.freeradbiomed. 2009.12.024
    • Fukui M, Zhu BT (2010) Mitochondrial superoxide dismutase SOD2, but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells. Free Radic Biol Med 48:821-830
    • (2010) Free Radic Biol Med , vol.48 , pp. 821-830
    • Fukui, M.1    Zhu, B.T.2
  • 10
    • 55649114157 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and its potential role in retinal degeneration
    • 1:CAS:528:DC%2BD1cXhtlyiu73K 18848639 10.1016/j.preteyeres.2008.09.001
    • Jarrett SG, Lin H, Godley BF, Boulton ME (2008) Mitochondrial DNA damage and its potential role in retinal degeneration. Prog Retin Eye Res 27:596-607
    • (2008) Prog Retin Eye Res , vol.27 , pp. 596-607
    • Jarrett, S.G.1    Lin, H.2    Godley, B.F.3    Boulton, M.E.4
  • 11
    • 80052788505 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies
    • 1:CAS:528:DC%2BC3MXhtF2rtL%2FM 20691180 10.1016/j.exer.2010.07.015
    • Lee S, Van Bergen NJ, Kong GY, Kong GY, Chrysostomou V, Waugh HS et al (2011) Mitochondrial dysfunction in glaucoma and emerging bioenergetic therapies. Exp Eye Res 93:204-212
    • (2011) Exp Eye Res , vol.93 , pp. 204-212
    • Lee, S.1    Van Bergen, N.J.2    Kong, G.Y.3    Kong, G.Y.4    Chrysostomou, V.5    Waugh, H.S.6
  • 12
    • 0031930319 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
    • 1:CAS:528:DyaK1cXhtlKktL8%3D 9500544 10.1038/ng0398-231
    • Larsson NG, Wang J, Wilhelmsson H, Oldfors A, Rustin P, Lewandoski M et al (1998) Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet 18:231-236
    • (1998) Nat Genet , vol.18 , pp. 231-236
    • Larsson, N.G.1    Wang, J.2    Wilhelmsson, H.3    Oldfors, A.4    Rustin, P.5    Lewandoski, M.6
  • 13
    • 33845744837 scopus 로고    scopus 로고
    • Initiation and beyond: Multiple functions of the human mitochondrial transcription machinery
    • 1:CAS:528:DC%2BD2sXmvVyqtA%3D%3D 17189185 10.1016/j.molcel.2006.11.024
    • Bonawitz ND, Clayton DA, Shadel GS (2006) Initiation and beyond: multiple functions of the human mitochondrial transcription machinery. Mol Cell 24:813-825
    • (2006) Mol Cell , vol.24 , pp. 813-825
    • Bonawitz, N.D.1    Clayton, D.A.2    Shadel, G.S.3
  • 14
    • 34548627532 scopus 로고    scopus 로고
    • DNA replication and transcription in mammalian mitochondria
    • 1:CAS:528:DC%2BD2sXhtVehtbzK 17408359 10.1146/annurev.biochem.76.060305. 152028
    • Falkenberg M, Larsson NG, Gustafsson CM (2007) DNA replication and transcription in mammalian mitochondria. Annu Rev Biochem 76:679-699
    • (2007) Annu Rev Biochem , vol.76 , pp. 679-699
    • Falkenberg, M.1    Larsson, N.G.2    Gustafsson, C.M.3
  • 15
    • 80555128721 scopus 로고    scopus 로고
    • The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA
    • 1:CAS:528:DC%2BC3MXhtl2gs7fF 3210390 22037171 10.1038/nsmb.2159
    • Ngo HB, Kaiser JT, Chan DC (2011) The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA. Nat Struct Mol Biol 18:1290-1296
    • (2011) Nat Struct Mol Biol , vol.18 , pp. 1290-1296
    • Ngo, H.B.1    Kaiser, J.T.2    Chan, D.C.3
  • 16
    • 67650655697 scopus 로고    scopus 로고
    • Overexpression of Tfam protects mitochondria against beta-amyloid-induced oxidative damage in SH-SY5Y cells
    • 1:CAS:528:DC%2BD1MXovV2lsbk%3D 19496804 10.1111/j.1742-4658.2009.07094.x
    • Xu S, Zhong M, Zhang L, Wang Y, Zhou Z, Hao Y et al (2009) Overexpression of Tfam protects mitochondria against beta-amyloid-induced oxidative damage in SH-SY5Y cells. FEBS J 276:3800-3809
    • (2009) FEBS J , vol.276 , pp. 3800-3809
    • Xu, S.1    Zhong, M.2    Zhang, L.3    Wang, Y.4    Zhou, Z.5    Hao, Y.6
  • 17
    • 77954829313 scopus 로고    scopus 로고
    • Overexpression of mitochondrial transcription factor A (TFAM) ameliorates delayed neuronal death due to transient forebrain ischemia in mice
    • 20102525 10.1111/j.1440-1789.2009.01086.x
    • Hokari M, Kuroda S, Kinugawa S, Ide T, Tsutsui H, Iwasaki Y (2010) Overexpression of mitochondrial transcription factor A (TFAM) ameliorates delayed neuronal death due to transient forebrain ischemia in mice. Neuropathology 30:401-407
    • (2010) Neuropathology , vol.30 , pp. 401-407
    • Hokari, M.1    Kuroda, S.2    Kinugawa, S.3    Ide, T.4    Tsutsui, H.5    Iwasaki, Y.6
  • 18
    • 84859422737 scopus 로고    scopus 로고
    • Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells
    • 1:CAS:528:DC%2BC38XltVKltb0%3D 21856379 10.1016/j.bbagen.2011.08.007
    • Piao Y, Kim HG, Oh MS, Pak YK (2012) Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells. Biochim Biophys Acta 1820:577-585
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 577-585
    • Piao, Y.1    Kim, H.G.2    Oh, M.S.3    Pak, Y.K.4
  • 19
    • 55749114205 scopus 로고    scopus 로고
    • Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury
    • 2726706 18723421 10.1161/STROKEAHA.108.520114
    • Yin W, Signore AP, Iwai M, Cao G, Gao Y, Chen J (2008) Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. Stroke 39:3057-3063
    • (2008) Stroke , vol.39 , pp. 3057-3063
    • Yin, W.1    Signore, A.P.2    Iwai, M.3    Cao, G.4    Gao, Y.5    Chen, J.6
  • 20
    • 0347419379 scopus 로고    scopus 로고
    • Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease
    • 1:CAS:528:DC%2BD3sXpsFenu7w%3D 14695931 10.1002/biof.5520180218
    • Beal MF, Shults CW (2003) Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease. Biofactors 18:153-161
    • (2003) Biofactors , vol.18 , pp. 153-161
    • Beal, M.F.1    Shults, C.W.2
  • 21
    • 7444253528 scopus 로고    scopus 로고
    • Paraquat induces oxidative stress and neuronal cell death; Neuroprotection by water-soluble Coenzyme Q10
    • 1:CAS:528:DC%2BD2cXpt1Wju7g%3D 15519605 10.1016/j.taap.2004.04.019
    • McCarthy S, Somayajulu M, Sikorska M, Borowy-Borowski H, Pandey S (2004) Paraquat induces oxidative stress and neuronal cell death; neuroprotection by water-soluble Coenzyme Q10. Toxicol Appl Pharmacol 201:21-31
    • (2004) Toxicol Appl Pharmacol , vol.201 , pp. 21-31
    • McCarthy, S.1    Somayajulu, M.2    Sikorska, M.3    Borowy-Borowski, H.4    Pandey, S.5
  • 22
    • 74049109447 scopus 로고    scopus 로고
    • Neuroprotection for optic nerve disorders
    • 19915465 10.1097/WCO.0b013e3283344461
    • Bessero AC, Clarke PG (2010) Neuroprotection for optic nerve disorders. Curr Opin Neurol 23:10-15
    • (2010) Curr Opin Neurol , vol.23 , pp. 10-15
    • Bessero, A.C.1    Clarke, P.G.2
  • 23
    • 48849101467 scopus 로고    scopus 로고
    • Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo
    • 1:CAS:528:DC%2BD1cXpvFGmt7s%3D 18598676 10.1016/j.brainres.2008.06.026
    • Nakajima Y, Inokuchi Y, Nishi M, Shimazawa M, Otsubo K, Hara H (2008) Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo. Brain Res 1226:226-233
    • (2008) Brain Res , vol.1226 , pp. 226-233
    • Nakajima, Y.1    Inokuchi, Y.2    Nishi, M.3    Shimazawa, M.4    Otsubo, K.5    Hara, H.6
  • 24
    • 53049096965 scopus 로고    scopus 로고
    • Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection
    • 1:CAS:528:DC%2BD1MXmtVamtg%3D%3D 18929135 10.1016/S0079-6123(08)01139-4
    • Russo R, Cavaliere F, Rombola L, Gliozzi M, Cerulli A, Nucci C et al (2008) Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection. Prog Brain Res 173:575-582
    • (2008) Prog Brain Res , vol.173 , pp. 575-582
    • Russo, R.1    Cavaliere, F.2    Rombola, L.3    Gliozzi, M.4    Cerulli, A.5    Nucci, C.6
  • 25
    • 34547551906 scopus 로고    scopus 로고
    • Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat
    • 1:CAS:528:DC%2BD2sXhtVWqs7zL 17678974 10.1016/S0074-7742(07)82022-8
    • Nucci C, Tartaglione R, Cerulli A, Mancino R, Spano A, Cavaliere F et al (2007) Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat. Int Rev Neurobiol 82:397-406
    • (2007) Int Rev Neurobiol , vol.82 , pp. 397-406
    • Nucci, C.1    Tartaglione, R.2    Cerulli, A.3    Mancino, R.4    Spano, A.5    Cavaliere, F.6
  • 26
    • 65549091910 scopus 로고    scopus 로고
    • Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases
    • 1:CAS:528:DC%2BD1MXntVCis78%3D 2866530 19476553 10.1111/j.1471-4159.2009. 06074.x
    • Yang L, Calingasan NY, Wille EJ, Cormier K, Smith K, Ferrante RJ et al (2009) Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. J Neurochem 109:1427-1439
    • (2009) J Neurochem , vol.109 , pp. 1427-1439
    • Yang, L.1    Calingasan, N.Y.2    Wille, E.J.3    Cormier, K.4    Smith, K.5    Ferrante, R.J.6
  • 27
    • 20044361858 scopus 로고    scopus 로고
    • OPA1 expression in the normal rat retina and optic nerve
    • 1:CAS:528:DC%2BD2MXlslWgtL4%3D 1350956 15912498 10.1002/cne.20586
    • Ju WK, Misaka T, Kushnareva Y, Nakagomi S, Agarwal N, Kubo Y et al (2005) OPA1 expression in the normal rat retina and optic nerve. J Comp Neurol 488:1-10
    • (2005) J Comp Neurol , vol.488 , pp. 1-10
    • Ju, W.K.1    Misaka, T.2    Kushnareva, Y.3    Nakagomi, S.4    Agarwal, N.5    Kubo, Y.6
  • 31
    • 34249693479 scopus 로고    scopus 로고
    • A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy
    • 17314202 10.1093/brain/awm005
    • Alavi MV, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF et al (2007) A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. Brain 130:1029-1042
    • (2007) Brain , vol.130 , pp. 1029-1042
    • Alavi, M.V.1    Bette, S.2    Schimpf, S.3    Schuettauf, F.4    Schraermeyer, U.5    Wehrl, H.F.6
  • 32
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • 1:CAS:528:DC%2BD1cXmvVemt7c%3D 18546601 10.1038/nprot.2008.73
    • Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3:1101-1108
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 33
    • 84555219107 scopus 로고    scopus 로고
    • Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography
    • 3047363 21412463 10.1364/BOE.2.000579
    • Zhi Z, Cepurna W, Johnson E, Shen T, Morrison J, Wang RK (2011) Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography. Biomed Opt Express 2:579-591
    • (2011) Biomed Opt Express , vol.2 , pp. 579-591
    • Zhi, Z.1    Cepurna, W.2    Johnson, E.3    Shen, T.4    Morrison, J.5    Wang, R.K.6
  • 34
    • 79960116416 scopus 로고    scopus 로고
    • Measuring glutamate receptor activation-induced apoptotic cell death in ischemic rat retina using the TUNEL assay
    • 1:CAS:528:DC%2BC3MXntlaktLg%3D 21468976 10.1007/978-1-61779-108-6-16
    • Ju WK, Kim KY (2011) Measuring glutamate receptor activation-induced apoptotic cell death in ischemic rat retina using the TUNEL assay. Methods Mol Biol 740:149-156
    • (2011) Methods Mol Biol , vol.740 , pp. 149-156
    • Ju, W.K.1    Kim, K.Y.2
  • 35
    • 84873378188 scopus 로고    scopus 로고
    • Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage
    • 1:CAS:528:DC%2BC3sXjsFGhtbc%3D 23154463 10.1167/iovs.12-10374
    • Lulli M, Witort E, Papucci L, Torre E, Schipani C, Bergamini C et al (2012) Coenzyme Q10 instilled as eye drops on the cornea reaches the retina and protects retinal layers from apoptosis in a mouse model of kainate-induced retinal damage. Invest Ophthalmol Vis Sci 53:8295-8302
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 8295-8302
    • Lulli, M.1    Witort, E.2    Papucci, L.3    Torre, E.4    Schipani, C.5    Bergamini, C.6
  • 36
    • 84872777505 scopus 로고    scopus 로고
    • Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo
    • 1:CAS:528:DC%2BC38XhsFCmtrfL 3430426 22843363 10.1093/jrr/rrs025
    • Lulli M, Witort E, Papucci L, Torre E, Schiavone N, Dal Monte M et al (2012) Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. J Radiat Res 53:695-703
    • (2012) J Radiat Res , vol.53 , pp. 695-703
    • Lulli, M.1    Witort, E.2    Papucci, L.3    Torre, E.4    Schiavone, N.5    Dal Monte, M.6
  • 37
    • 0038576896 scopus 로고    scopus 로고
    • Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma
    • 12824248
    • Tezel G, Chauhan BC, LeBlanc RP, Wax MB (2003) Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma. Invest Ophthalmol Vis Sci 44:3025-3033
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3025-3033
    • Tezel, G.1    Chauhan, B.C.2    Leblanc, R.P.3    Wax, M.B.4
  • 39
    • 45549084028 scopus 로고    scopus 로고
    • Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2 J mouse model of glaucoma
    • 18385061 10.1167/iovs.07-1337
    • Bosco A, Inman DM, Steele MR, Wu G, Soto I, Marsh-Armstrong N et al (2008) Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2 J mouse model of glaucoma. Invest Ophthalmol Vis Sci 49:1437-1446
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 1437-1446
    • Bosco, A.1    Inman, D.M.2    Steele, M.R.3    Wu, G.4    Soto, I.5    Marsh-Armstrong, N.6
  • 40
    • 0036523110 scopus 로고    scopus 로고
    • Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease
    • 1:CAS:528:DC%2BD38XhvValsbc%3D 11880489
    • Ferrante RJ, Andreassen OA, Dedeoglu A, Ferrante KL, Jenkins BG, Hersch SM et al (2002) Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J Neurosci 22:1592-1599
    • (2002) J Neurosci , vol.22 , pp. 1592-1599
    • Ferrante, R.J.1    Andreassen, O.A.2    Dedeoglu, A.3    Ferrante, K.L.4    Jenkins, B.G.5    Hersch, S.M.6
  • 41
    • 53049102476 scopus 로고    scopus 로고
    • Assessment of neuroprotection in the retina with DARC
    • 1:CAS:528:DC%2BD1MXmtVanug%3D%3D 2603274 18929126 10.1016/S0079-6123(08) 01130-8
    • Guo L, Cordeiro MF (2008) Assessment of neuroprotection in the retina with DARC. Prog Brain Res 173:437-450
    • (2008) Prog Brain Res , vol.173 , pp. 437-450
    • Guo, L.1    Cordeiro, M.F.2
  • 42
    • 34247172100 scopus 로고    scopus 로고
    • Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein
    • 1:CAS:528:DC%2BD2sXksFWnt74%3D 16806588 10.1016/j.neurobiolaging.2006.05. 005
    • Li G, Zou L, Jack CR Jr, Yang Y, Yang ES (2007) Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein. Neurobiol Aging 28:877-882
    • (2007) Neurobiol Aging , vol.28 , pp. 877-882
    • Li, G.1    Zou, L.2    Jack, Jr.C.R.3    Yang, Y.4    Yang, E.S.5
  • 43
    • 33645099245 scopus 로고    scopus 로고
    • Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics
    • 1:CAS:528:DC%2BD28Xis1CjtbY%3D 16551570 10.1080/10715760600617843
    • Bhagavan HN, Chopra RK (2006) Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res 40:445-453
    • (2006) Free Radic Res , vol.40 , pp. 445-453
    • Bhagavan, H.N.1    Chopra, R.K.2
  • 44
    • 0023902809 scopus 로고
    • Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutase
    • 1:CAS:528:DyaL1cXkvVOhtrs%3D 2831093 10.1016/0014-5793(88)81136-0
    • Ho YS, Crapo JD (1988) Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutase. FEBS Lett 229:256-260
    • (1988) FEBS Lett , vol.229 , pp. 256-260
    • Ho, Y.S.1    Crapo, J.D.2
  • 45
    • 27244451344 scopus 로고    scopus 로고
    • SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: Implications for age-related macular degeneration
    • 1237007 16123448 10.1167/iovs.05-0344
    • Kasahara E, Lin LR, Ho YS, Reddy VN (2005) SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci 46:3426-3434
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 3426-3434
    • Kasahara, E.1    Lin, L.R.2    Ho, Y.S.3    Reddy, V.N.4
  • 46
    • 28244447656 scopus 로고    scopus 로고
    • Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: Role in cell proliferation and response to oxidative stress
    • 1:CAS:528:DC%2BD2MXht1ems77M 16179351 10.1074/jbc.M503296200
    • Hu Y, Rosen DG, Zhou Y, Feng L, Yang G, Liu J et al (2005) Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress. J Biol Chem 280:39485-39492
    • (2005) J Biol Chem , vol.280 , pp. 39485-39492
    • Hu, Y.1    Rosen, D.G.2    Zhou, Y.3    Feng, L.4    Yang, G.5    Liu, J.6
  • 47
    • 6144275971 scopus 로고    scopus 로고
    • Effect of coenzyme Q10 on superoxide production in rats with reperfusion injuries
    • 1:STN:280:DyaK1M3isVeltw%3D%3D 10207958 10.1080/02844319950159550
    • Yokoyama K, Nakamura K, Kimura M, Nomoto K, Itoman M (1999) Effect of coenzyme Q10 on superoxide production in rats with reperfusion injuries. Scand J Plast Reconstr Surg Hand Surg 33:1-5
    • (1999) Scand J Plast Reconstr Surg Hand Surg , vol.33 , pp. 1-5
    • Yokoyama, K.1    Nakamura, K.2    Kimura, M.3    Nomoto, K.4    Itoman, M.5
  • 48
    • 84862777338 scopus 로고    scopus 로고
    • Effects of antioxidant gene therapy on retinal neurons and oxidative stress in a model of retinal ischemia/reperfusion
    • 1:CAS:528:DC%2BC38XitVWltb8%3D 22240151 10.1016/j.freeradbiomed.2011.12. 013
    • Liu Y, Tang L, Chen B (2012) Effects of antioxidant gene therapy on retinal neurons and oxidative stress in a model of retinal ischemia/reperfusion. Free Radic Biol Med 52:909-915
    • (2012) Free Radic Biol Med , vol.52 , pp. 909-915
    • Liu, Y.1    Tang, L.2    Chen, B.3
  • 49
    • 73349128447 scopus 로고    scopus 로고
    • Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature
    • 3756491 19628743 10.1167/iovs.09-3633
    • Chen B, Caballero S, Seo S, Grant MB, Lewin AS (2009) Delivery of antioxidant enzyme genes to protect against ischemia/reperfusion-induced injury to retinal microvasculature. Invest Ophthalmol Vis Sci 50:5587-5595
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 5587-5595
    • Chen, B.1    Caballero, S.2    Seo, S.3    Grant, M.B.4    Lewin, A.S.5
  • 50
    • 51349168245 scopus 로고    scopus 로고
    • Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro
    • 18442093 10.1002/glia.20683
    • Rohl C, Armbrust E, Kolbe K, Lucius R, Maser E, Venz S et al (2008) Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro. Glia 56:1114-1126
    • (2008) Glia , vol.56 , pp. 1114-1126
    • Rohl, C.1    Armbrust, E.2    Kolbe, K.3    Lucius, R.4    Maser, E.5    Venz, S.6
  • 51
    • 0032917291 scopus 로고    scopus 로고
    • Anti-death properties of TNF against metabolic poisoning: Mitochondrial stabilization by MnSOD
    • 1:CAS:528:DyaK1MXhslahtQ%3D%3D 10378869 10.1016/S0165-5728(98)00190-8
    • Bruce-Keller AJ, Geddes JW, Knapp PE, McFall RQ, Keller JN, Holtsberg FW et al (1999) Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD. J Neuroimmunol 93:53-71
    • (1999) J Neuroimmunol , vol.93 , pp. 53-71
    • Bruce-Keller, A.J.1    Geddes, J.W.2    Knapp, P.E.3    McFall, R.Q.4    Keller, J.N.5    Holtsberg, F.W.6
  • 52
    • 33846818874 scopus 로고    scopus 로고
    • 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes
    • 1:CAS:528:DC%2BD2sXhs1Cms70%3D 1832079 17173895 10.1016/j.exer.2006.10. 020
    • Malone PE, Hernandez MR (2007) 4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes. Exp Eye Res 84:444-454
    • (2007) Exp Eye Res , vol.84 , pp. 444-454
    • Malone, P.E.1    Hernandez, M.R.2
  • 53
    • 53049094645 scopus 로고    scopus 로고
    • Astrocytes in glaucomatous optic neuropathy
    • 1:CAS:528:DC%2BD1MXmtVantg%3D%3D 18929121 10.1016/S0079-6123(08)01125-4
    • Hernandez MR, Miao H, Lukas T (2008) Astrocytes in glaucomatous optic neuropathy. Prog Brain Res 173:353-373
    • (2008) Prog Brain Res , vol.173 , pp. 353-373
    • Hernandez, M.R.1    Miao, H.2    Lukas, T.3
  • 54
    • 34347380194 scopus 로고    scopus 로고
    • Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina
    • 1:CAS:528:DC%2BD2sXmsFSgsr4%3D 17485853 10.1271/bbb.60657
    • Lee I, Lee H, Kim JM, Chae EH, Kim SJ, Chang N (2007) Short-term hyperhomocysteinemia-induced oxidative stress activates retinal glial cells and increases vascular endothelial growth factor expression in rat retina. Biosci Biotechnol Biochem 71:1203-1210
    • (2007) Biosci Biotechnol Biochem , vol.71 , pp. 1203-1210
    • Lee, I.1    Lee, H.2    Kim, J.M.3    Chae, E.H.4    Kim, S.J.5    Chang, N.6
  • 55
    • 78149489635 scopus 로고    scopus 로고
    • Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling
    • 3061506 20538986 10.1167/iovs.10-5407
    • Luo C, Yang X, Kain AD, Powell DW, Kuehn MH, Tezel G (2010) Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci 51:5697-5707
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 5697-5707
    • Luo, C.1    Yang, X.2    Kain, A.D.3    Powell, D.W.4    Kuehn, M.H.5    Tezel, G.6
  • 56
    • 79957460640 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors
    • 1:CAS:528:DC%2BC3MXmsVehsLY%3D 3102025 21617752
    • McElnea EM, Quill B, Docherty NG, Irnaten M, Siah WF, Clark AF et al (2011) Oxidative stress, mitochondrial dysfunction and calcium overload in human lamina cribrosa cells from glaucoma donors. Mol Vis 17:1182-1191
    • (2011) Mol Vis , vol.17 , pp. 1182-1191
    • McElnea, E.M.1    Quill, B.2    Docherty, N.G.3    Irnaten, M.4    Siah, W.F.5    Clark, A.F.6
  • 57
    • 79956049847 scopus 로고    scopus 로고
    • Quantification of the effect of different levels of IOP in the astroglia of the rat retina ipsilateral and contralateral to experimental glaucoma
    • 20538983 10.1167/iovs.10-5248
    • Ramirez AI, Salazar JJ, de Hoz R, Rojas B, Gallego BI, Sallinas-Navarro M et al (2010) Quantification of the effect of different levels of IOP in the astroglia of the rat retina ipsilateral and contralateral to experimental glaucoma. Invest Ophthalmol Vis Sci 51:5690-5696
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 5690-5696
    • Ramirez, A.I.1    Salazar, J.J.2    De Hoz, R.3    Rojas, B.4    Gallego, B.I.5    Sallinas-Navarro, M.6
  • 58
    • 84860815301 scopus 로고    scopus 로고
    • IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma
    • 1:CAS:528:DC%2BC38Xhsl2jt7vL 3410794 22583833 10.1186/1742-2094-9-92
    • Gallego BI, Salazar JJ, de Hoz R, Rojas B, Ramirez AI, Salinas-Navarro M et al (2012) IOP induces upregulation of GFAP and MHC-II and microglia reactivity in mice retina contralateral to experimental glaucoma. J Neuroinflammation 9:92
    • (2012) J Neuroinflammation , vol.9 , pp. 92
    • Gallego, B.I.1    Salazar, J.J.2    De Hoz, R.3    Rojas, B.4    Ramirez, A.I.5    Salinas-Navarro, M.6
  • 59
    • 0035957653 scopus 로고    scopus 로고
    • Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
    • 1:CAS:528:DC%2BD3MXjt1eltr0%3D 3049805 11326099 10.1126/science.1059108
    • Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ et al (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-730
    • (2001) Science , vol.292 , pp. 727-730
    • Wei, M.C.1    Zong, W.X.2    Cheng, E.H.3    Lindsten, T.4    Panoutsakopoulou, V.5    Ross, A.J.6
  • 60
    • 34248182897 scopus 로고    scopus 로고
    • Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death
    • 1:CAS:528:DC%2BD2sXltF2gtrc%3D 2064824 17470634 10.1083/jcb.200610042
    • Wasiak S, Zunino R, McBride HM (2007) Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol 177:439-450
    • (2007) J Cell Biol , vol.177 , pp. 439-450
    • Wasiak, S.1    Zunino, R.2    McBride, H.M.3
  • 61
    • 9844257587 scopus 로고    scopus 로고
    • Inhibition of Bax channel-forming activity by Bcl-2
    • 1:CAS:528:DyaK2sXkvVels7s%3D 9219694 10.1126/science.277.5324.370
    • Antonsson B, Conti F, Ciavatta A, Montessuit S, Lewis S, Martinou I et al (1997) Inhibition of Bax channel-forming activity by Bcl-2. Science 277:370-372
    • (1997) Science , vol.277 , pp. 370-372
    • Antonsson, B.1    Conti, F.2    Ciavatta, A.3    Montessuit, S.4    Lewis, S.5    Martinou, I.6
  • 62
    • 0030779846 scopus 로고    scopus 로고
    • Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2
    • 1:CAS:528:DyaK2sXmslejtr8%3D 23466 9326614 10.1073/pnas.94.21.11357
    • Schlesinger PH, Gross A, Yin XM, Yamamoto K, Saito M, Waksman G et al (1997) Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2. Proc Natl Acad Sci USA 94:11357-11362
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 11357-11362
    • Schlesinger, P.H.1    Gross, A.2    Yin, X.M.3    Yamamoto, K.4    Saito, M.5    Waksman, G.6
  • 63
    • 0034284637 scopus 로고    scopus 로고
    • Mitochondria as the central control point of apoptosis
    • 1:CAS:528:DC%2BD3cXls1CktLk%3D 10932094 10.1016/S0962-8924(00)01803-1
    • Desagher S, Martinou JC (2000) Mitochondria as the central control point of apoptosis. Trends Cell Biol 10:369-377
    • (2000) Trends Cell Biol , vol.10 , pp. 369-377
    • Desagher, S.1    Martinou, J.C.2
  • 64
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • 1:CAS:528:DyaK3sXms1eqtbs%3D 8358790 10.1016/0092-8674(93)90509-O
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 65
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
    • 1:CAS:528:DyaK2MXjtlGns78%3D 7834748 10.1016/0092-8674(95)90411-5
    • Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ (1995) Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80:285-291
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3    Boise, L.H.4    Thompson, C.B.5    Korsmeyer, S.J.6
  • 66
    • 34247485841 scopus 로고    scopus 로고
    • Role of the mitochondrial membrane permeability transition in cell death
    • 1:CAS:528:DC%2BD2sXksFamsbg%3D 17136322 10.1007/s10495-006-0525-7
    • Tsujimoto Y, Shimizu S (2007) Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 12:835-840
    • (2007) Apoptosis , vol.12 , pp. 835-840
    • Tsujimoto, Y.1    Shimizu, S.2
  • 67
    • 84880357849 scopus 로고    scopus 로고
    • Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
    • 1:CAS:528:DC%2BC3sXht1emurfN 3718149 23818611 10.1073/pnas.1305538110
    • Linkermann A, Brasen JH, Darding M, Jin MK, Sanz AB, Heller JO et al (2013) Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury. Proc Natl Acad Sci USA 110:12024-12029
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 12024-12029
    • Linkermann, A.1    Brasen, J.H.2    Darding, M.3    Jin, M.K.4    Sanz, A.B.5    Heller, J.O.6
  • 68
    • 80053562653 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is sensitive to exogenous H(2)O(2) but independent of cellular ROS production in prostate cancer cells
    • 1:CAS:528:DC%2BC3MXht1Gru7vF 21843533 10.1016/j.mrfmmm.2011.07.019
    • Chan SW, Nguyen PN, Ayele D, Chevalier S, Aprikian A, Chen JZ (2011) Mitochondrial DNA damage is sensitive to exogenous H(2)O(2) but independent of cellular ROS production in prostate cancer cells. Mutat Res 716:40-50
    • (2011) Mutat Res , vol.716 , pp. 40-50
    • Chan, S.W.1    Nguyen, P.N.2    Ayele, D.3    Chevalier, S.4    Aprikian, A.5    Chen, J.Z.6
  • 69
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • 1:CAS:528:DyaK2MXosl2ls7c%3D 7668820 10.1002/ana.410380304
    • Beal MF (1995) Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38:357-366
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 70
    • 2442431673 scopus 로고    scopus 로고
    • Mitochondrial transcription factor A regulates mtDNA copy number in mammals
    • 1:CAS:528:DC%2BD2cXivFyhur0%3D 15016765 10.1093/hmg/ddh109
    • Ekstrand MI, Falkenberg M, Rantanen A, Park CB, Gaspari M, Hultenby K et al (2004) Mitochondrial transcription factor A regulates mtDNA copy number in mammals. Hum Mol Genet 13:935-944
    • (2004) Hum Mol Genet , vol.13 , pp. 935-944
    • Ekstrand, M.I.1    Falkenberg, M.2    Rantanen, A.3    Park, C.B.4    Gaspari, M.5    Hultenby, K.6


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