-
1
-
-
61649091807
-
Parkinson's disease and cancer: Insights for pathogenesis from epidemiology
-
M. D'Amelio, P. Ragonese, G. Sconzo, P. Aridon, and G. Savettieri Parkinson's disease and cancer: insights for pathogenesis from epidemiology Ann. N. Y. Acad. Sci. 1155 2009 324 334
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1155
, pp. 324-334
-
-
D'Amelio, M.1
Ragonese, P.2
Sconzo, G.3
Aridon, P.4
Savettieri, G.5
-
2
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
DOI 10.1002/ana.21022
-
J. Hardy, H. Cai, M.R. Cookson, K. Gwinn-Hardy, and A. Singleton Genetics of Parkinson's disease and parkinsonism Ann. Neurol. 60 2006 389 398 (Pubitemid 44684974)
-
(2006)
Annals of Neurology
, vol.60
, Issue.4
, pp. 389-398
-
-
Hardy, J.1
Cai, H.2
Cookson, M.R.3
Gwinn-Hardy, K.4
Singleton, A.5
-
3
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
DOI 10.1016/S0896-6273(03)00568-3
-
W. Dauer, and S. Przedborski Parkinson's disease: mechanisms and models Neuron 39 2003 889 909 (Pubitemid 37130207)
-
(2003)
Neuron
, vol.39
, Issue.6
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
4
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
M.G. Spillantini, M.L. Schmidt, V.M. Lee, J.Q. Trojanowski, R. Jakes, and M. Goedert Alpha-synuclein in Lewy bodies Nature 388 1997 839 840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
5
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
C. Henchcliffe, and M.F. Beal Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis Nat. Clin. Pract. Neurol. 4 2008 600 609
-
(2008)
Nat. Clin. Pract. Neurol.
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
7
-
-
33644610520
-
The genetics of Parkinson disease: Implications for neurological care
-
C. Klein, and M.G. Schlossmacher The genetics of Parkinson disease: implications for neurological care Nat. Clin. Pract. Neurol. 2 2006 136 146
-
(2006)
Nat. Clin. Pract. Neurol.
, vol.2
, pp. 136-146
-
-
Klein, C.1
Schlossmacher, M.G.2
-
8
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
D.P. Narendra, S.M. Jin, A. Tanaka, D.F. Suen, C.A. Gautier, J. Shen, M.R. Cookson, and R.J. Youle PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biol. 8 2010 e1000298
-
(2010)
PLoS Biol.
, vol.8
, pp. 1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
9
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
I. Irrcher, H. Aleyasin, E.L. Seifert, S.J. Hewitt, S. Chhabra, M. Phillips, A.K. Lutz, M.W. Rousseaux, L. Bevilacqua, A. Jahani-Asl, S. Callaghan, J.G. MacLaurin, K.F. Winklhofer, P. Rizzu, P. Rippstein, R.H. Kim, C.X. Chen, E.A. Fon, R.S. Slack, M.E. Harper, H.M. McBride, T.W. Mak, and D.S. Park Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics Hum. Mol. Genet. 19 2010 3734 3746
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
Callaghan, S.11
MacLaurin, J.G.12
Winklhofer, K.F.13
Rizzu, P.14
Rippstein, P.15
Kim, R.H.16
Chen, C.X.17
Fon, E.A.18
Slack, R.S.19
Harper, M.E.20
McBride, H.M.21
Mak, T.W.22
Park, D.S.23
more..
-
10
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: Clinical and molecular genetic study
-
DOI 10.1016/S0140-6736(04)16983-3, PII S0140673604169833
-
P. Luoma, A. Melberg, J.O. Rinne, J.A. Kaukonen, N.N. Nupponen, R.M. Chalmers, A. Oldfors, I. Rautakorpi, L. Peltonen, K. Majamaa, H. Somer, and A. Suomalainen Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study Lancet 364 2004 875 882 (Pubitemid 39221065)
-
(2004)
Lancet
, vol.364
, Issue.9437
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
Oldfors, P.A.7
Rautakorpi, I.8
Peltonen, P.L.9
Majamaa, P.K.10
Somer, H.11
Suomalainen, A.12
-
11
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
-
DOI 10.1523/JNEUROSCI.0984-06.2006
-
P.M. Keeney, J. Xie, R.A. Capaldi, and J.P. Bennett Jr. Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled J. Neurosci. 26 2006 5256 5264 (Pubitemid 44315308)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.19
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett Jr., J.P.4
-
12
-
-
0025047351
-
Normal mitochondrial genome in brain from patients with Parkinson's disease and complex i defect
-
P. Lestienne, J. Nelson, P. Riederer, K. Jellinger, and H. Reichmann Normal mitochondrial genome in brain from patients with Parkinson's disease and complex I defect J. Neurochem. 55 1990 1810 1812
-
(1990)
J. Neurochem.
, vol.55
, pp. 1810-1812
-
-
Lestienne, P.1
Nelson, J.2
Riederer, P.3
Jellinger, K.4
Reichmann, H.5
-
13
-
-
0033967662
-
18FDG-PET study
-
M.T. Hu, S.D. Taylor-Robinson, K.R. Chaudhuri, J.D. Bell, C. Labbe, V.J. Cunningham, M.J. Koepp, A. Hammers, R.G. Morris, N. Turjanski, and D.J. Brooks Cortical dysfunction in non-demented Parkinson's disease patients: a combined (31)P-MRS and (18)FDG-PET study Brain 123 Pt 2 2000 340 352 (Pubitemid 30055157)
-
(2000)
Brain
, vol.123
, Issue.2
, pp. 340-352
-
-
Hu, M.T.M.1
Taylor-Robinson, S.D.2
Chaudhuri, K.R.3
Bell, J.D.4
Labbe, C.5
Cunningham, V.J.6
Koepp, M.J.7
Hammers, A.8
Morris, R.G.9
Turjanski, N.10
Brooks, D.J.11
-
14
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage
-
T.B. Sherer, R. Betarbet, A.K. Stout, S. Lund, M. Baptista, A.V. Panov, M.R. Cookson, and J.T. Greenamyre An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage J. Neurosci. 22 2002 7006 7015 (Pubitemid 35379158)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.16
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
Cookson, M.R.7
Greenamyre, J.T.8
-
15
-
-
0036010592
-
Animal models of Parkinson's disease
-
DOI 10.1002/bies.10067
-
R. Betarbet, T.B. Sherer, and J.T. Greenamyre Animal models of Parkinson's disease Bioessays 24 2002 308 318 (Pubitemid 34305686)
-
(2002)
BioEssays
, vol.24
, Issue.4
, pp. 308-318
-
-
Betarbet, R.1
Sherer, T.B.2
Timothy Greenamyre, J.3
-
16
-
-
0023186383
-
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain
-
DOI 10.1111/j.1471-4159.1987.tb05737.x
-
Y. Mizuno, N. Sone, and T. Saitoh Effects of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain J. Neurochem. 48 1987 1787 1793 (Pubitemid 17101550)
-
(1987)
Journal of Neurochemistry
, vol.48
, Issue.6
, pp. 1787-1793
-
-
Mizuno, Y.1
Sone, N.2
Saitoh, T.3
-
17
-
-
0026718086
-
Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease
-
V.M. Mann, J.M. Cooper, D. Krige, S.E. Daniel, A.H. Schapira, and C.D. Marsden Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease Brain 115 Pt 2 1992 333 342
-
(1992)
Brain
, vol.115
, Issue.PART 2
, pp. 333-342
-
-
Mann, V.M.1
Cooper, J.M.2
Krige, D.3
Daniel, S.E.4
Schapira, A.H.5
Marsden, C.D.6
-
18
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
DOI 10.1038/nature05292, PII NATURE05292
-
M.T. Lin, and M.F. Beal Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases Nature 443 2006 787 795 (Pubitemid 44622683)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
19
-
-
0027561888
-
The relationship between diabetes mellitus and Parkinson's disease
-
R. Sandyk The relationship between diabetes mellitus and Parkinson's disease Int. J. Neurosci. 69 1993 125 130
-
(1993)
Int. J. Neurosci.
, vol.69
, pp. 125-130
-
-
Sandyk, R.1
-
20
-
-
54549097933
-
Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease
-
J.K. Morris, H. Zhang, A.A. Gupte, G.L. Bomhoff, J.A. Stanford, and P.C. Geiger Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease Brain Res. 1240 2008 185 195
-
(2008)
Brain Res.
, vol.1240
, pp. 185-195
-
-
Morris, J.K.1
Zhang, H.2
Gupte, A.A.3
Bomhoff, G.L.4
Stanford, J.A.5
Geiger, P.C.6
-
21
-
-
70349581633
-
Insulin resistance and Alzheimer's disease
-
S.M. de la Monte Insulin resistance and Alzheimer's disease BMB Rep. 42 2009 475 481
-
(2009)
BMB Rep.
, vol.42
, pp. 475-481
-
-
De La Monte, S.M.1
-
22
-
-
76749110211
-
Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation
-
S.Y. Ahn, Y.S. Choi, H.J. Koo, J.H. Jeong, W.H. Park, M. Kim, Y. Piao, and Y.K. Pak Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation Biochim. Biophys. Acta 1800 2010 275 281
-
(2010)
Biochim. Biophys. Acta
, vol.1800
, pp. 275-281
-
-
Ahn, S.Y.1
Choi, Y.S.2
Koo, H.J.3
Jeong, J.H.4
Park, W.H.5
Kim, M.6
Piao, Y.7
Pak, Y.K.8
-
23
-
-
65249107688
-
Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance
-
S. Lim, S.Y. Ahn, I.C. Song, M.H. Chung, H.C. Jang, K.S. Park, K.U. Lee, Y.K. Pak, and H.K. Lee Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance PLoS One 4 2009 e5186
-
(2009)
PLoS One
, vol.4
, pp. 5186
-
-
Lim, S.1
Ahn, S.Y.2
Song, I.C.3
Chung, M.H.4
Jang, H.C.5
Park, K.S.6
Lee, K.U.7
Pak, Y.K.8
Lee, H.K.9
-
24
-
-
0027323932
-
Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells
-
DOI 10.1016/0896-6273(93)90187-V
-
D.R. Kaplan, K. Matsumoto, E. Lucarelli, and C.J. Thiele Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells. Eukaryotic Signal Transduction Group Neuron 11 1993 321 331 (Pubitemid 23250349)
-
(1993)
Neuron
, vol.11
, Issue.2
, pp. 321-331
-
-
Kaplan, D.R.1
Matsumoto, K.2
Lucarelli, E.3
Thiele, C.J.4
-
25
-
-
0346095167
-
In vitro methylation of nuclear respiratory factor-1 binding site suppresses the promoter activity of mitochondrial transcription factor A
-
DOI 10.1016/j.bbrc.2003.12.065
-
Y.S. Choi, S. Kim, H. Kyu Lee, K.U. Lee, and Y.K. Pak In vitro methylation of nuclear respiratory factor-1 binding site suppresses the promoter activity of mitochondrial transcription factor A Biochem. Biophys. Res. Commun. 314 2004 118 122 (Pubitemid 38058377)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.314
, Issue.1
, pp. 118-122
-
-
Choi, Y.S.1
Kim, S.2
Lee, H.K.3
Lee, K.-U.4
Pak, Y.K.5
-
26
-
-
2342562963
-
Regulation of mitochondrial transcription factor A expression by high glucose
-
DOI 10.1196/annals.1293.008
-
Y.S. Choi, K.U. Lee, and Y.K. Pak Regulation of mitochondrial transcription factor A expression by high glucose Ann. N. Y. Acad. Sci. 1011 2004 69 77 (Pubitemid 38608393)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1011
, pp. 69-77
-
-
Choi, Y.S.1
Lee, K.-U.2
Pak, Y.K.3
-
27
-
-
76749110211
-
Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation
-
S.Y. Ahn, Y.S. Choi, H.J. Koo, J.H. Jeong, W.H. Park, M. Kim, Y. Piao, and Y.K. Pak Mitochondrial dysfunction enhances the migration of vascular smooth muscles cells via suppression of Akt phosphorylation Biochim. Biophys. Acta 1800 2009 275 281
-
(2009)
Biochim. Biophys. Acta
, vol.1800
, pp. 275-281
-
-
Ahn, S.Y.1
Choi, Y.S.2
Koo, H.J.3
Jeong, J.H.4
Park, W.H.5
Kim, M.6
Piao, Y.7
Pak, Y.K.8
-
28
-
-
0033621455
-
Oxidation-dependent effects of oxidized LDL: Proliferation or cell death
-
C.Y. Han, and Y.K. Pak Oxidation-dependent effects of oxidized LDL: proliferation or cell death Exp. Mol. Med. 31 1999 165 173 (Pubitemid 30021332)
-
(1999)
Experimental and Molecular Medicine
, vol.31
, Issue.4
, pp. 165-173
-
-
Han, C.-Y.1
Pak, Y.K.2
-
29
-
-
79954526957
-
Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: Identification of mitochondrial histones
-
Y.S. Choi, J. Hoon Jeong, H.K. Min, H.J. Jung, D. Hwang, S.W. Lee, and Y. Kim Pak Shot-gun proteomic analysis of mitochondrial D-loop DNA binding proteins: identification of mitochondrial histones Mol. Biosyst. 7 2011 1523 1536
-
(2011)
Mol. Biosyst.
, vol.7
, pp. 1523-1536
-
-
Choi, Y.S.1
Hoon Jeong, J.2
Min, H.K.3
Jung, H.J.4
Hwang, D.5
Lee, S.W.6
Kim Pak, Y.7
-
30
-
-
34547700335
-
The depletion of cellular mitochondrial DNA causes insulin resistance through the alteration of insulin receptor substrate-1 in rat myocytes
-
S.Y. Park, and W. Lee The depletion of cellular mitochondrial DNA causes insulin resistance through the alteration of insulin receptor substrate-1 in rat myocytes Diabetes Res. Clin. Pract. 77 Suppl. 1 2007 S165 S171
-
(2007)
Diabetes Res. Clin. Pract.
, vol.77
, Issue.SUPPL. 1
-
-
Park, S.Y.1
Lee, W.2
-
31
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
N. Matsuda, S. Sato, K. Shiba, K. Okatsu, K. Saisho, C.A. Gautier, Y.S. Sou, S. Saiki, S. Kawajiri, F. Sato, M. Kimura, M. Komatsu, N. Hattori, and K. Tanaka PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy J. Cell. Biol. 189 2010 211 221
-
(2010)
J. Cell. Biol.
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
Kimura, M.11
Komatsu, M.12
Hattori, N.13
Tanaka, K.14
-
32
-
-
0028011017
-
Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: A potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis
-
J.V. Virbasius, and R.C. Scarpulla Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis Proc. Natl. Acad. Sci. U. S. A. 91 1994 1309 1313 (Pubitemid 24059000)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.4
, pp. 1309-1313
-
-
Virbasius, J.V.1
Scarpulla, R.C.2
-
33
-
-
28844495644
-
Insulin receptor signaling in long-term memory consolidation following spatial learning
-
DOI 10.1101/lm.88005
-
J.T. Dou, M. Chen, F. Dufour, D.L. Alkon, and W.Q. Zhao Insulin receptor signaling in long-term memory consolidation following spatial learning Learn. Mem. 12 2005 646 655 (Pubitemid 41770090)
-
(2005)
Learning and Memory
, vol.12
, Issue.6
, pp. 646-655
-
-
Dou, J.-T.1
Chen, M.2
Dufour, F.3
Alkon, D.L.4
Zhao, W.-Q.5
-
34
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease: Implications for treatment
-
DOI 10.2165/00023210-200317010-00003
-
G.S. Watson, and S. Craft The role of insulin resistance in the pathogenesis of Alzheimer's disease: implications for treatment CNS Drugs 17 2003 27 45 (Pubitemid 36044347)
-
(2003)
CNS Drugs
, vol.17
, Issue.1
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
35
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
-
D.R. Alessi, S.R. James, C.P. Downes, A.B. Holmes, P.R. Gaffney, C.B. Reese, and P. Cohen Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha Curr. Biol. 7 1997 261 269 (Pubitemid 27176852)
-
(1997)
Current Biology
, vol.7
, Issue.4
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.J.5
Reese, C.B.6
Cohen, P.7
-
36
-
-
77957372038
-
Mitochondria: The secrete chamber of therapeutic targets for age-associated degenerative diseases
-
Y.K. Pak, and J.H. Jeong Mitochondria: the secrete chamber of therapeutic targets for age-associated degenerative diseases Biomolecules Ther. 18 2010 235 245
-
(2010)
Biomolecules Ther.
, vol.18
, pp. 235-245
-
-
Pak, Y.K.1
Jeong, J.H.2
|