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Volumn 24, Issue 6, 2006, Pages 813-825

Initiation and Beyond: Multiple Functions of the Human Mitochondrial Transcription Machinery

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; MITOCHONDRIAL RNA; RIBOSOME RNA; RNA METHYLTRANSFERASE; RNA POLYMERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTTFA; TRANSCRIPTION FACTOR MTTFB1; TRANSCRIPTION FACTOR MTTFB2; UNCLASSIFIED DRUG;

EID: 33845744837     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.11.024     Document Type: Review
Times cited : (288)

References (96)
  • 1
    • 33646163885 scopus 로고    scopus 로고
    • Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration
    • Amiott E.A., and Jaehning J.A. Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration. Mol. Cell 22 (2006) 329-338
    • (2006) Mol. Cell , vol.22 , pp. 329-338
    • Amiott, E.A.1    Jaehning, J.A.2
  • 2
    • 0030946172 scopus 로고    scopus 로고
    • The HMG-box mitochondrial transcription factor xl-mtTFA binds DNA as a tetramer to activate bidirectional transcription
    • Antoshechkin I., Bogenhagen D.F., and Mastrangelo I.A. The HMG-box mitochondrial transcription factor xl-mtTFA binds DNA as a tetramer to activate bidirectional transcription. EMBO J. 16 (1997) 3198-3206
    • (1997) EMBO J. , vol.16 , pp. 3198-3206
    • Antoshechkin, I.1    Bogenhagen, D.F.2    Mastrangelo, I.A.3
  • 3
    • 2442601523 scopus 로고    scopus 로고
    • A monomer-to-trimer transition of the human mitochondrial transcription termination factor (mTERF) is associated with a loss of in vitro activity
    • Asin-Cayuela J., Helm M., and Attardi G. A monomer-to-trimer transition of the human mitochondrial transcription termination factor (mTERF) is associated with a loss of in vitro activity. J. Biol. Chem. 279 (2004) 15670-15677
    • (2004) J. Biol. Chem. , vol.279 , pp. 15670-15677
    • Asin-Cayuela, J.1    Helm, M.2    Attardi, G.3
  • 4
    • 21844466466 scopus 로고    scopus 로고
    • The human mitochondrial transcription termination factor (mTERF) is fully active in vitro in the non-phosphorylated form
    • Asin-Cayuela J., Schwend T., Farge G., and Gustafsson C.M. The human mitochondrial transcription termination factor (mTERF) is fully active in vitro in the non-phosphorylated form. J. Biol. Chem. 280 (2005) 25499-25505
    • (2005) J. Biol. Chem. , vol.280 , pp. 25499-25505
    • Asin-Cayuela, J.1    Schwend, T.2    Farge, G.3    Gustafsson, C.M.4
  • 5
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • Balaban R.S., Nemoto S., and Finkel T. Mitochondria, oxidants, and aging. Cell 120 (2005) 483-495
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.S.1    Nemoto, S.2    Finkel, T.3
  • 6
    • 15844420658 scopus 로고    scopus 로고
    • Interaction of mtTFB and mtRNA polymerase at core promoters for transcription of Xenopus laevis mtDNA
    • Bogenhagen D.F. Interaction of mtTFB and mtRNA polymerase at core promoters for transcription of Xenopus laevis mtDNA. J. Biol. Chem. 271 (1996) 12036-12041
    • (1996) J. Biol. Chem. , vol.271 , pp. 12036-12041
    • Bogenhagen, D.F.1
  • 7
    • 0042157173 scopus 로고    scopus 로고
    • Concluding remarks: The mitochondrial DNA replication bubble has not burst
    • Bogenhagen D.F., and Clayton D.A. Concluding remarks: The mitochondrial DNA replication bubble has not burst. Trends Biochem. Sci. 28 (2003) 404-405
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 404-405
    • Bogenhagen, D.F.1    Clayton, D.A.2
  • 8
    • 0038109027 scopus 로고    scopus 로고
    • The mitochondrial DNA replication bubble has not burst
    • Bogenhagen D.F., and Clayton D.A. The mitochondrial DNA replication bubble has not burst. Trends Biochem. Sci. 28 (2003) 357-360
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 357-360
    • Bogenhagen, D.F.1    Clayton, D.A.2
  • 9
    • 33745473351 scopus 로고    scopus 로고
    • Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span
    • Bonawitz N.D., Rodeheffer M.S., and Shadel G.S. Defective mitochondrial gene expression results in reactive oxygen species-mediated inhibition of respiration and reduction of yeast life span. Mol. Cell. Biol. 26 (2006) 4818-4829
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4818-4829
    • Bonawitz, N.D.1    Rodeheffer, M.S.2    Shadel, G.S.3
  • 10
    • 26944500840 scopus 로고    scopus 로고
    • Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism
    • Brown T.A., Cecconi C., Tkachuk A.N., Bustamante C., and Clayton D.A. Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism. Genes Dev. 19 (2005) 2466-2476
    • (2005) Genes Dev. , vol.19 , pp. 2466-2476
    • Brown, T.A.1    Cecconi, C.2    Tkachuk, A.N.3    Bustamante, C.4    Clayton, D.A.5
  • 11
    • 0036160242 scopus 로고    scopus 로고
    • Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression
    • Bryan A.C., Rodeheffer M.S., Wearn C.M., and Shadel G.S. Sls1p is a membrane-bound regulator of transcription-coupled processes involved in Saccharomyces cerevisiae mitochondrial gene expression. Genetics 160 (2002) 75-82
    • (2002) Genetics , vol.160 , pp. 75-82
    • Bryan, A.C.1    Rodeheffer, M.S.2    Wearn, C.M.3    Shadel, G.S.4
  • 12
    • 1942425120 scopus 로고    scopus 로고
    • Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation
    • Bykhovskaya Y., Mengesha E., Wang D., Yang H., Estivill X., Shohat M., and Fischel-Ghodsian N. Human mitochondrial transcription factor B1 as a modifier gene for hearing loss associated with the mitochondrial A1555G mutation. Mol. Genet. Metab. 82 (2004) 27-32
    • (2004) Mol. Genet. Metab. , vol.82 , pp. 27-32
    • Bykhovskaya, Y.1    Mengesha, E.2    Wang, D.3    Yang, H.4    Estivill, X.5    Shohat, M.6    Fischel-Ghodsian, N.7
  • 13
    • 0007662353 scopus 로고
    • Priming of human mitochondrial DNA replication occurs at the light-strand promoter
    • Chang D.D., and Clayton D.A. Priming of human mitochondrial DNA replication occurs at the light-strand promoter. Proc. Natl. Acad. Sci. USA 82 (1985) 351-355
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 351-355
    • Chang, D.D.1    Clayton, D.A.2
  • 14
    • 0022081437 scopus 로고
    • Replication priming and transcription initiate from precisely the same site in mouse mitochondrial DNA
    • Chang D.D., Hauswirth W.W., and Clayton D.A. Replication priming and transcription initiate from precisely the same site in mouse mitochondrial DNA. EMBO J. 4 (1985) 1559-1567
    • (1985) EMBO J. , vol.4 , pp. 1559-1567
    • Chang, D.D.1    Hauswirth, W.W.2    Clayton, D.A.3
  • 15
    • 0019978703 scopus 로고
    • Replication of animal mitochondrial DNA
    • Clayton D.A. Replication of animal mitochondrial DNA. Cell 28 (1982) 693-705
    • (1982) Cell , vol.28 , pp. 693-705
    • Clayton, D.A.1
  • 16
    • 0030813608 scopus 로고    scopus 로고
    • Identification of three regions essential for interaction between a sigma-like factor and core RNA polymerase
    • Cliften P.F., Park J.Y., Davis B.P., Jang S.H., and Jaehning J.A. Identification of three regions essential for interaction between a sigma-like factor and core RNA polymerase. Genes Dev. 11 (1997) 2897-2909
    • (1997) Genes Dev. , vol.11 , pp. 2897-2909
    • Cliften, P.F.1    Park, J.Y.2    Davis, B.P.3    Jang, S.H.4    Jaehning, J.A.5
  • 17
    • 0025695227 scopus 로고
    • Control of mitochondrial gene expression in Saccharomyces cerevisiae
    • Costanzo M.C., and Fox T.D. Control of mitochondrial gene expression in Saccharomyces cerevisiae. Annu. Rev. Genet. 24 (1990) 91-113
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 91-113
    • Costanzo, M.C.1    Fox, T.D.2
  • 18
    • 33751521683 scopus 로고    scopus 로고
    • Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2
    • Cotney J.L., and Shadel G.S. Evidence for an early gene duplication event in the evolution of the mitochondrial transcription factor B family and maintenance of rRNA methyltransferase activity in human mtTFB1 and mtTFB2. J. Mol. Evol. 63 (2006) 707-717
    • (2006) J. Mol. Evol. , vol.63 , pp. 707-717
    • Cotney, J.L.1    Shadel, G.S.2
  • 19
    • 0029070402 scopus 로고
    • Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator
    • Dairaghi D.J., Shadel G.S., and Clayton D.A. Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator. J. Mol. Biol. 249 (1995) 11-28
    • (1995) J. Mol. Biol. , vol.249 , pp. 11-28
    • Dairaghi, D.J.1    Shadel, G.S.2    Clayton, D.A.3
  • 20
    • 0029006975 scopus 로고
    • Human mitochondrial transcription factor A and promoter spacing integrity are required for transcription initiation
    • Dairaghi D.J., Shadel G.S., and Clayton D.A. Human mitochondrial transcription factor A and promoter spacing integrity are required for transcription initiation. Biochim. Biophys. Acta 1271 (1995) 127-134
    • (1995) Biochim. Biophys. Acta , vol.1271 , pp. 127-134
    • Dairaghi, D.J.1    Shadel, G.S.2    Clayton, D.A.3
  • 24
    • 0031048845 scopus 로고    scopus 로고
    • The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions
    • Fernandez-Silva P., Martinez-Azorin F., Micol V., and Attardi G. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 16 (1997) 1066-1079
    • (1997) EMBO J. , vol.16 , pp. 1066-1079
    • Fernandez-Silva, P.1    Martinez-Azorin, F.2    Micol, V.3    Attardi, G.4
  • 25
    • 0037252462 scopus 로고    scopus 로고
    • Replication and transcription of mammalian mitochondrial DNA
    • Fernandez-Silva P., Enriquez J.A., and Montoya J. Replication and transcription of mammalian mitochondrial DNA. Exp. Physiol. 88 (2003) 41-56
    • (2003) Exp. Physiol. , vol.88 , pp. 41-56
    • Fernandez-Silva, P.1    Enriquez, J.A.2    Montoya, J.3
  • 26
    • 10844295852 scopus 로고    scopus 로고
    • Discovery of a major D-loop replication origin reveals two modes of human mtDNA synthesis
    • Fish J., Raule N., and Attardi G. Discovery of a major D-loop replication origin reveals two modes of human mtDNA synthesis. Science 306 (2004) 2098-2101
    • (2004) Science , vol.306 , pp. 2098-2101
    • Fish, J.1    Raule, N.2    Attardi, G.3
  • 27
    • 0023684801 scopus 로고
    • Purification and characterization of human mitochondrial transcription factor 1
    • Fisher R.P., and Clayton D.A. Purification and characterization of human mitochondrial transcription factor 1. Mol. Cell. Biol. 8 (1988) 3496-3509
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3496-3509
    • Fisher, R.P.1    Clayton, D.A.2
  • 28
    • 0023658329 scopus 로고
    • Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements
    • Fisher R.P., Topper J.N., and Clayton D.A. Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements. Cell 50 (1987) 247-258
    • (1987) Cell , vol.50 , pp. 247-258
    • Fisher, R.P.1    Topper, J.N.2    Clayton, D.A.3
  • 29
    • 0024811763 scopus 로고
    • Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1
    • Fisher R.P., Parisi M.A., and Clayton D.A. Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1. Genes Dev. 3 (1989) 2202-2217
    • (1989) Genes Dev. , vol.3 , pp. 2202-2217
    • Fisher, R.P.1    Parisi, M.A.2    Clayton, D.A.3
  • 30
    • 0023259258 scopus 로고
    • Markedly different ATP requirements for rRNA synthesis and mtDNA light strand transcription versus mRNA synthesis in isolated human mitochondria
    • Gaines G., Rossi C., and Attardi G. Markedly different ATP requirements for rRNA synthesis and mtDNA light strand transcription versus mRNA synthesis in isolated human mitochondria. J. Biol. Chem. 262 (1987) 1907-1915
    • (1987) J. Biol. Chem. , vol.262 , pp. 1907-1915
    • Gaines, G.1    Rossi, C.2    Attardi, G.3
  • 31
    • 10644229290 scopus 로고    scopus 로고
    • The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells
    • Gaspari M., Falkenberg M., Larsson N.G., and Gustafsson C.M. The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells. EMBO J. 23 (2004) 4606-4614
    • (2004) EMBO J. , vol.23 , pp. 4606-4614
    • Gaspari, M.1    Falkenberg, M.2    Larsson, N.G.3    Gustafsson, C.M.4
  • 32
    • 0035444293 scopus 로고    scopus 로고
    • Mechanism of mammalian mitochondrial DNA replication: import of mitochondrial transcription factor A into isolated mitochondria stimulates 7S DNA synthesis
    • Gensler S., Weber K., Schmitt W.E., Perez-Martos A., Enriquez J.A., Montoya J., and Weisner R.J. Mechanism of mammalian mitochondrial DNA replication: import of mitochondrial transcription factor A into isolated mitochondria stimulates 7S DNA synthesis. Nucleic Acids Res. 29 (2001) 3657-3663
    • (2001) Nucleic Acids Res. , vol.29 , pp. 3657-3663
    • Gensler, S.1    Weber, K.2    Schmitt, W.E.3    Perez-Martos, A.4    Enriquez, J.A.5    Montoya, J.6    Weisner, R.J.7
  • 33
    • 13444306450 scopus 로고    scopus 로고
    • Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators
    • Gleyzer N., Vercauteren K., and Scarpulla R.C. Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators. Mol. Cell. Biol. 25 (2005) 1354-1366
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 1354-1366
    • Gleyzer, N.1    Vercauteren, K.2    Scarpulla, R.C.3
  • 34
    • 0022497229 scopus 로고
    • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome
    • Greenleaf A.L., Kelly J.L., and Lehman I.R. Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. Proc. Natl. Acad. Sci. USA 83 (1986) 3391-3394
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 3391-3394
    • Greenleaf, A.L.1    Kelly, J.L.2    Lehman, I.R.3
  • 35
    • 0038825342 scopus 로고    scopus 로고
    • Response: the mitochondrial DNA replication bubble has not burst
    • Holt I.J., and Jacobs H.T. Response: the mitochondrial DNA replication bubble has not burst. Trends Biochem. Sci. 28 (2003) 355-356
    • (2003) Trends Biochem. Sci. , vol.28 , pp. 355-356
    • Holt, I.J.1    Jacobs, H.T.2
  • 36
    • 0034598918 scopus 로고    scopus 로고
    • Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA
    • Holt I.J., Lorimer H.E., and Jacobs H.T. Coupled leading- and lagging-strand synthesis of mammalian mitochondrial DNA. Cell 100 (2000) 515-524
    • (2000) Cell , vol.100 , pp. 515-524
    • Holt, I.J.1    Lorimer, H.E.2    Jacobs, H.T.3
  • 37
    • 19444380425 scopus 로고    scopus 로고
    • Nuclear genes and mitochondrial translation: a new class of genetic disease
    • Jacobs H.T., and Turnbull D.M. Nuclear genes and mitochondrial translation: a new class of genetic disease. Trends Genet. 21 (2005) 312-314
    • (2005) Trends Genet. , vol.21 , pp. 312-314
    • Jacobs, H.T.1    Turnbull, D.M.2
  • 38
    • 0027462374 scopus 로고
    • Mitochondrial transcription: is a pattern emerging?
    • Jaehning J.A. Mitochondrial transcription: is a pattern emerging?. Mol. Microbiol. 8 (1993) 1-4
    • (1993) Mol. Microbiol. , vol.8 , pp. 1-4
    • Jaehning, J.A.1
  • 39
    • 0025876118 scopus 로고
    • The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors
    • Jang S.H., and Jaehning J.A. The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors. J. Biol. Chem. 266 (1991) 22671-22677
    • (1991) J. Biol. Chem. , vol.266 , pp. 22671-22677
    • Jang, S.H.1    Jaehning, J.A.2
  • 40
    • 2342429459 scopus 로고    scopus 로고
    • DNA polymerase gamma, the mitochondrial replicase
    • Kaguni L.S. DNA polymerase gamma, the mitochondrial replicase. Annu. Rev. Biochem. 73 (2004) 293-320
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 293-320
    • Kaguni, L.S.1
  • 42
    • 1542373685 scopus 로고    scopus 로고
    • Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
    • Kelly D.P., and Scarpulla R.C. Transcriptional regulatory circuits controlling mitochondrial biogenesis and function. Genes Dev. 18 (2004) 357-368
    • (2004) Genes Dev. , vol.18 , pp. 357-368
    • Kelly, D.P.1    Scarpulla, R.C.2
  • 43
    • 3242739284 scopus 로고    scopus 로고
    • Reconstitution of a minimal mtDNA replisome in vitro
    • Korhonen J.A., Pham X.H., Pellegrini M., and Falkenberg M. Reconstitution of a minimal mtDNA replisome in vitro. EMBO J. 23 (2004) 2423-2429
    • (2004) EMBO J. , vol.23 , pp. 2423-2429
    • Korhonen, J.A.1    Pham, X.H.2    Pellegrini, M.3    Falkenberg, M.4
  • 44
    • 23644459685 scopus 로고    scopus 로고
    • Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin
    • Kravchenko J.E., Rogozin I.B., Koonin E.V., and Chumakov P.M. Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin. Nature 436 (2005) 735-739
    • (2005) Nature , vol.436 , pp. 735-739
    • Kravchenko, J.E.1    Rogozin, I.B.2    Koonin, E.V.3    Chumakov, P.M.4
  • 45
    • 0024365289 scopus 로고
    • Termination of transcription in human mitochondria: identification and purification of a DNA binding protein factor that promotes termination
    • Kruse B., Narasimhan N., and Attardi G. Termination of transcription in human mitochondria: identification and purification of a DNA binding protein factor that promotes termination. Cell 58 (1989) 391-397
    • (1989) Cell , vol.58 , pp. 391-397
    • Kruse, B.1    Narasimhan, N.2    Attardi, G.3
  • 46
    • 0028223609 scopus 로고
    • Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion
    • Larsson N.G., Oldfors A., Holme E., and Clayton D.A. Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion. Biochem. Biophys. Res. Commun. 200 (1994) 1374-1381
    • (1994) Biochem. Biophys. Res. Commun. , vol.200 , pp. 1374-1381
    • Larsson, N.G.1    Oldfors, A.2    Holme, E.3    Clayton, D.A.4
  • 47
    • 0029957097 scopus 로고    scopus 로고
    • A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein
    • Larsson N.G., Garman J.D., Oldfors A., Barsh G.S., and Clayton D.A. A single mouse gene encodes the mitochondrial transcription factor A and a testis-specific nuclear HMG-box protein. Nat. Genet. 13 (1996) 296-302
    • (1996) Nat. Genet. , vol.13 , pp. 296-302
    • Larsson, N.G.1    Garman, J.D.2    Oldfors, A.3    Barsh, G.S.4    Clayton, D.A.5
  • 48
    • 0031065006 scopus 로고    scopus 로고
    • Structure and chromosomal localization of the mouse mitochondrial transcription factor A gene (Tfam)
    • Larsson N.G., Barsh G.S., and Clayton D.A. Structure and chromosomal localization of the mouse mitochondrial transcription factor A gene (Tfam). Mamm. Genome 8 (1997) 139-140
    • (1997) Mamm. Genome , vol.8 , pp. 139-140
    • Larsson, N.G.1    Barsh, G.S.2    Clayton, D.A.3
  • 50
    • 0029796960 scopus 로고    scopus 로고
    • Properties of a primer RNA-DNA hybrid at the mouse mitochondrial DNA leading-strand origin of replication
    • Lee D.Y., and Clayton D.A. Properties of a primer RNA-DNA hybrid at the mouse mitochondrial DNA leading-strand origin of replication. J. Biol. Chem. 271 (1996) 24262-24269
    • (1996) J. Biol. Chem. , vol.271 , pp. 24262-24269
    • Lee, D.Y.1    Clayton, D.A.2
  • 51
    • 0030952327 scopus 로고    scopus 로고
    • RNase mitochondrial RNA processing correctly cleaves a novel R loop at the mitochondrial DNA leading-strand origin of replication
    • Lee D.Y., and Clayton D.A. RNase mitochondrial RNA processing correctly cleaves a novel R loop at the mitochondrial DNA leading-strand origin of replication. Genes Dev. 11 (1997) 582-592
    • (1997) Genes Dev. , vol.11 , pp. 582-592
    • Lee, D.Y.1    Clayton, D.A.2
  • 52
    • 0032514892 scopus 로고    scopus 로고
    • Initiation of mitochondrial DNA replication by transcription and R-loop processing
    • Lee D.Y., and Clayton D.A. Initiation of mitochondrial DNA replication by transcription and R-loop processing. J. Biol. Chem. 273 (1998) 30614-30621
    • (1998) J. Biol. Chem. , vol.273 , pp. 30614-30621
    • Lee, D.Y.1    Clayton, D.A.2
  • 53
  • 54
    • 29244468548 scopus 로고    scopus 로고
    • Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis
    • Martin M., Cho J., Cesare A.J., Griffith J.D., and Attardi G. Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis. Cell 123 (2005) 1227-1240
    • (2005) Cell , vol.123 , pp. 1227-1240
    • Martin, M.1    Cho, J.2    Cesare, A.J.3    Griffith, J.D.4    Attardi, G.5
  • 55
    • 0023649273 scopus 로고
    • Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7
    • Masters B.S., Stohl L.L., and Clayton D.A. Yeast mitochondrial RNA polymerase is homologous to those encoded by bacteriophages T3 and T7. Cell 51 (1987) 89-99
    • (1987) Cell , vol.51 , pp. 89-99
    • Masters, B.S.1    Stohl, L.L.2    Clayton, D.A.3
  • 56
    • 7244232840 scopus 로고    scopus 로고
    • Intrinsic promoter recognition by a "core" RNA polymerase
    • Matsunaga M., and Jaehning J.A. Intrinsic promoter recognition by a "core" RNA polymerase. J. Biol. Chem. 279 (2004) 44239-44242
    • (2004) J. Biol. Chem. , vol.279 , pp. 44239-44242
    • Matsunaga, M.1    Jaehning, J.A.2
  • 57
    • 0041731714 scopus 로고    scopus 로고
    • Functional domains of chicken mitochondrial transcription factor A for the maintenance of mitochondrial DNA copy number in lymphoma cell line DT40
    • Matsushima Y., Matsumura K., Ishii S., Inagaki H., Suzuki T., Matsuda Y., Beck K., and Kitagawa Y. Functional domains of chicken mitochondrial transcription factor A for the maintenance of mitochondrial DNA copy number in lymphoma cell line DT40. J. Biol. Chem. 278 (2003) 31149-31158
    • (2003) J. Biol. Chem. , vol.278 , pp. 31149-31158
    • Matsushima, Y.1    Matsumura, K.2    Ishii, S.3    Inagaki, H.4    Suzuki, T.5    Matsuda, Y.6    Beck, K.7    Kitagawa, Y.8
  • 58
    • 3042695377 scopus 로고    scopus 로고
    • Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in Schneider cells
    • Matsushima Y., Garesse R., and Kaguni L.S. Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in Schneider cells. J. Biol. Chem. 279 (2004) 26900-26905
    • (2004) J. Biol. Chem. , vol.279 , pp. 26900-26905
    • Matsushima, Y.1    Garesse, R.2    Kaguni, L.S.3
  • 59
    • 20444458289 scopus 로고    scopus 로고
    • Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells
    • Matsushima Y., Adan C., Garesse R., and Kaguni L.S. Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells. J. Biol. Chem. 280 (2005) 16815-16820
    • (2005) J. Biol. Chem. , vol.280 , pp. 16815-16820
    • Matsushima, Y.1    Adan, C.2    Garesse, R.3    Kaguni, L.S.4
  • 60
    • 0036148610 scopus 로고    scopus 로고
    • A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine
    • McCulloch V., Seidel-Rogol B.L., and Shadel G.S. A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine. Mol. Cell. Biol. 22 (2002) 1116-1125
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1116-1125
    • McCulloch, V.1    Seidel-Rogol, B.L.2    Shadel, G.S.3
  • 61
    • 0042632864 scopus 로고    scopus 로고
    • Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity
    • McCulloch V., and Shadel G.S. Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity. Mol. Cell. Biol. 23 (2003) 5816-5824
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5816-5824
    • McCulloch, V.1    Shadel, G.S.2
  • 62
    • 33748983242 scopus 로고    scopus 로고
    • Mitochondrial DNA transcription and diseases: Past, present and future
    • Montoya J., Lopez-Perez M.J., and Ruiz-Pesini E. Mitochondrial DNA transcription and diseases: Past, present and future. Biochim. Biophys. Acta 1757 (2006) 1179-1189
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 1179-1189
    • Montoya, J.1    Lopez-Perez, M.J.2    Ruiz-Pesini, E.3
  • 63
    • 0037238395 scopus 로고    scopus 로고
    • Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae
    • Naithani S., Saracco S.A., Butler C.A., and Fox T.D. Interactions among COX1, COX2, and COX3 mRNA-specific translational activator proteins on the inner surface of the mitochondrial inner membrane of Saccharomyces cerevisiae. Mol. Biol. Cell 14 (2003) 324-333
    • (2003) Mol. Biol. Cell , vol.14 , pp. 324-333
    • Naithani, S.1    Saracco, S.A.2    Butler, C.A.3    Fox, T.D.4
  • 64
    • 3242873102 scopus 로고
    • Specific requirement for ATP at an early step of in vitro transcription of human mitochondrial DNA
    • Narasimhan N., and Attardi G. Specific requirement for ATP at an early step of in vitro transcription of human mitochondrial DNA. Proc. Natl. Acad. Sci. USA 84 (1987) 4078-4082
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4078-4082
    • Narasimhan, N.1    Attardi, G.2
  • 65
    • 2342650072 scopus 로고    scopus 로고
    • Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli
    • O'Farrell H.C., Scarsdale J.N., and Rife J.P. Crystal structure of KsgA, a universally conserved rRNA adenine dimethyltransferase in Escherichia coli. J. Mol. Biol. 339 (2004) 337-353
    • (2004) J. Mol. Biol. , vol.339 , pp. 337-353
    • O'Farrell, H.C.1    Scarsdale, J.N.2    Rife, J.P.3
  • 66
    • 33646179813 scopus 로고    scopus 로고
    • Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution
    • O'Farrell H.C., Pulicherla N., Desai P.M., and Rife J.P. Recognition of a complex substrate by the KsgA/Dim1 family of enzymes has been conserved throughout evolution. RNA 12 (2006) 725-733
    • (2006) RNA , vol.12 , pp. 725-733
    • O'Farrell, H.C.1    Pulicherla, N.2    Desai, P.M.3    Rife, J.P.4
  • 67
    • 0019444843 scopus 로고
    • tRNA punctuation model of RNA processing in human mitochondria
    • Ojala D., Montoya J., and Attardi G. tRNA punctuation model of RNA processing in human mitochondria. Nature 290 (1981) 470-474
    • (1981) Nature , vol.290 , pp. 470-474
    • Ojala, D.1    Montoya, J.2    Attardi, G.3
  • 68
    • 0025829045 scopus 로고
    • Similarity of human mitochondrial transcription factor 1 to high mobility group proteins
    • Parisi M.A., and Clayton D.A. Similarity of human mitochondrial transcription factor 1 to high mobility group proteins. Science 252 (1991) 965-969
    • (1991) Science , vol.252 , pp. 965-969
    • Parisi, M.A.1    Clayton, D.A.2
  • 69
    • 33747639275 scopus 로고    scopus 로고
    • Conserved sequence box II directs transcription termination and primer formation in mitochondria
    • Pham X.H., Farge G., Shi Y., Gaspari M., Gustafsson C.M., and Falkenberg M. Conserved sequence box II directs transcription termination and primer formation in mitochondria. J. Biol. Chem. 281 (2006) 24647-24652
    • (2006) J. Biol. Chem. , vol.281 , pp. 24647-24652
    • Pham, X.H.1    Farge, G.2    Shi, Y.3    Gaspari, M.4    Gustafsson, C.M.5    Falkenberg, M.6
  • 70
    • 0018868238 scopus 로고
    • Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3′ end of 16S ribosomal RNA of Escherichia coli. IV. The effect of the methylgroups on ribosomal subunit interaction
    • Poldermans B., Bakker H., and Van Knippenberg P.H. Studies on the function of two adjacent N6,N6-dimethyladenosines near the 3′ end of 16S ribosomal RNA of Escherichia coli. IV. The effect of the methylgroups on ribosomal subunit interaction. Nucleic Acids Res. 8 (1980) 143-151
    • (1980) Nucleic Acids Res. , vol.8 , pp. 143-151
    • Poldermans, B.1    Bakker, H.2    Van Knippenberg, P.H.3
  • 72
    • 2342481724 scopus 로고    scopus 로고
    • Phosphorylation of rat mitochondrial transcription termination factor (mTERF) is required for transcription termination but not for binding to DNA
    • Prieto-Martin A., Montoya J., and Martinez-Azorin F. Phosphorylation of rat mitochondrial transcription termination factor (mTERF) is required for transcription termination but not for binding to DNA. Nucleic Acids Res. 32 (2004) 2059-2068
    • (2004) Nucleic Acids Res. , vol.32 , pp. 2059-2068
    • Prieto-Martin, A.1    Montoya, J.2    Martinez-Azorin, F.3
  • 73
    • 32544445370 scopus 로고    scopus 로고
    • The mitochondrion as a primary site of action of steroid and thyroid hormones: presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells
    • Psarra A.M., Solakidi S., and Sekeris C.E. The mitochondrion as a primary site of action of steroid and thyroid hormones: presence and action of steroid and thyroid hormone receptors in mitochondria of animal cells. Mol. Cell. Endocrinol. 246 (2006) 21-33
    • (2006) Mol. Cell. Endocrinol. , vol.246 , pp. 21-33
    • Psarra, A.M.1    Solakidi, S.2    Sekeris, C.E.3
  • 74
    • 0037245552 scopus 로고    scopus 로고
    • Characterization of the mouse genes for mitochondrial transcription factors B1 and B2
    • Rantanen A., Gaspari M., Falkenberg M., Gustafsson C.M., and Larsson N.G. Characterization of the mouse genes for mitochondrial transcription factors B1 and B2. Mamm. Genome 14 (2003) 1-6
    • (2003) Mamm. Genome , vol.14 , pp. 1-6
    • Rantanen, A.1    Gaspari, M.2    Falkenberg, M.3    Gustafsson, C.M.4    Larsson, N.G.5
  • 75
    • 0035896652 scopus 로고    scopus 로고
    • Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase
    • Rodeheffer M.S., Boone B.E., Bryan A.C., and Shadel G.S. Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase. J. Biol. Chem. 276 (2001) 8616-8622
    • (2001) J. Biol. Chem. , vol.276 , pp. 8616-8622
    • Rodeheffer, M.S.1    Boone, B.E.2    Bryan, A.C.3    Shadel, G.S.4
  • 76
    • 0038043207 scopus 로고    scopus 로고
    • Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis
    • Rodeheffer M.S., and Shadel G.S. Multiple interactions involving the amino-terminal domain of yeast mtRNA polymerase determine the efficiency of mitochondrial protein synthesis. J. Biol. Chem. 278 (2003) 18695-18701
    • (2003) J. Biol. Chem. , vol.278 , pp. 18695-18701
    • Rodeheffer, M.S.1    Shadel, G.S.2
  • 77
    • 0034808120 scopus 로고    scopus 로고
    • Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription
    • Schubot F.D., Chen C.J., Rose J.P., Dailey T.A., Dailey H.A., and Wang B.C. Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci. 10 (2001) 1980-1988
    • (2001) Protein Sci. , vol.10 , pp. 1980-1988
    • Schubot, F.D.1    Chen, C.J.2    Rose, J.P.3    Dailey, T.A.4    Dailey, H.A.5    Wang, B.C.6
  • 78
    • 0036566855 scopus 로고    scopus 로고
    • Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells
    • Seidel-Rogol B.L., and Shadel G.S. Modulation of mitochondrial transcription in response to mtDNA depletion and repletion in HeLa cells. Nucleic Acids Res. 30 (2002) 1929-1934
    • (2002) Nucleic Acids Res. , vol.30 , pp. 1929-1934
    • Seidel-Rogol, B.L.1    Shadel, G.S.2
  • 79
    • 0037228525 scopus 로고    scopus 로고
    • Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop
    • Seidel-Rogol B.L., McCulloch V., and Shadel G.S. Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop. Nat. Genet. 33 (2003) 23-24
    • (2003) Nat. Genet. , vol.33 , pp. 23-24
    • Seidel-Rogol, B.L.1    McCulloch, V.2    Shadel, G.S.3
  • 80
    • 4444268726 scopus 로고    scopus 로고
    • Coupling the mitochondrial transcription machinery to human disease
    • Shadel G.S. Coupling the mitochondrial transcription machinery to human disease. Trends Genet. 20 (2004) 513-519
    • (2004) Trends Genet. , vol.20 , pp. 513-519
    • Shadel, G.S.1
  • 81
    • 0027166054 scopus 로고
    • Mitochondrial transcription initiation. Variation and conservation
    • Shadel G.S., and Clayton D.A. Mitochondrial transcription initiation. Variation and conservation. J. Biol. Chem. 268 (1993) 16083-16086
    • (1993) J. Biol. Chem. , vol.268 , pp. 16083-16086
    • Shadel, G.S.1    Clayton, D.A.2
  • 82
    • 0030920779 scopus 로고    scopus 로고
    • Mitochondrial DNA maintenance in vertebrates
    • Shadel G.S., and Clayton D.A. Mitochondrial DNA maintenance in vertebrates. Annu. Rev. Biochem. 66 (1997) 409-435
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 409-435
    • Shadel, G.S.1    Clayton, D.A.2
  • 83
    • 0021962152 scopus 로고
    • Characterization of an RNA polymerase activity from HeLa cell mitochondria, which initiates transcription at the heavy strand rRNA promoter and the light strand promoter in human mitochondrial DNA
    • Shuey D.J., and Attardi G. Characterization of an RNA polymerase activity from HeLa cell mitochondria, which initiates transcription at the heavy strand rRNA promoter and the light strand promoter in human mitochondrial DNA. J. Biol. Chem. 260 (1985) 1952-1958
    • (1985) J. Biol. Chem. , vol.260 , pp. 1952-1958
    • Shuey, D.J.1    Attardi, G.2
  • 84
    • 31444454598 scopus 로고    scopus 로고
    • Bacteriophage origins of mitochondrial replication and transcription proteins
    • Shutt T.E., and Gray M.W. Bacteriophage origins of mitochondrial replication and transcription proteins. Trends Genet. 22 (2006) 90-95
    • (2006) Trends Genet. , vol.22 , pp. 90-95
    • Shutt, T.E.1    Gray, M.W.2
  • 85
    • 33646886369 scopus 로고    scopus 로고
    • Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont
    • Shutt T.E., and Gray M.W. Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont. Mol. Biol. Evol. 23 (2006) 1169-1179
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 1169-1179
    • Shutt, T.E.1    Gray, M.W.2
  • 86
    • 0034938364 scopus 로고    scopus 로고
    • Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria
    • Spelbrink J.N., Li F.Y., Tiranti V., Nikali K., Yuan Q.P., Tariq M., Wanrooij S., Garrido N., Comi G., Morandi L., et al. Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria. Nat. Genet. 28 (2001) 223-231
    • (2001) Nat. Genet. , vol.28 , pp. 223-231
    • Spelbrink, J.N.1    Li, F.Y.2    Tiranti, V.3    Nikali, K.4    Yuan, Q.P.5    Tariq, M.6    Wanrooij, S.7    Garrido, N.8    Comi, G.9    Morandi, L.10
  • 88
    • 0035281548 scopus 로고    scopus 로고
    • HMG1 and 2, and related 'architectural' DNA-binding proteins
    • Thomas J.O., and Travers A.A. HMG1 and 2, and related 'architectural' DNA-binding proteins. Trends Biochem. Sci. 26 (2001) 167-174
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 167-174
    • Thomas, J.O.1    Travers, A.A.2
  • 89
    • 0030943170 scopus 로고    scopus 로고
    • Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database
    • Tiranti V., Savoia A., Forti F., D'Apolito M.F., Centra M., Rocchi M., and Zeviani M. Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database. Hum. Mol. Genet. 6 (1997) 615-625
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 615-625
    • Tiranti, V.1    Savoia, A.2    Forti, F.3    D'Apolito, M.F.4    Centra, M.5    Rocchi, M.6    Zeviani, M.7
  • 91
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine
    • Wallace D.C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39 (2005) 359-407
    • (2005) Annu. Rev. Genet. , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 92
    • 0033529190 scopus 로고    scopus 로고
    • Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase
    • Wang Y., and Shadel G.S. Stability of the mitochondrial genome requires an amino-terminal domain of yeast mitochondrial RNA polymerase. Proc. Natl. Acad. Sci. USA 96 (1999) 8046-8051
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8046-8051
    • Wang, Y.1    Shadel, G.S.2
  • 93
    • 0026598146 scopus 로고
    • Assignment of a yeast protein necessary for mitochondrial transcription initiation
    • Xu B., and Clayton D.A. Assignment of a yeast protein necessary for mitochondrial transcription initiation. Nucleic Acids Res. 20 (1992) 1053-1059
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1053-1059
    • Xu, B.1    Clayton, D.A.2
  • 94
    • 0028917766 scopus 로고
    • A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence
    • Xu B., and Clayton D.A. A persistent RNA-DNA hybrid is formed during transcription at a phylogenetically conserved mitochondrial DNA sequence. Mol. Cell. Biol. 15 (1995) 580-589
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 580-589
    • Xu, B.1    Clayton, D.A.2
  • 95
    • 0029938513 scopus 로고    scopus 로고
    • RNA-DNA hybrid formation at the human mitochondrial heavy-strand origin ceases at replication start sites: an implication for RNA-DNA hybrids serving as primers
    • Xu B., and Clayton D.A. RNA-DNA hybrid formation at the human mitochondrial heavy-strand origin ceases at replication start sites: an implication for RNA-DNA hybrids serving as primers. EMBO J. 15 (1996) 3135-3143
    • (1996) EMBO J. , vol.15 , pp. 3135-3143
    • Xu, B.1    Clayton, D.A.2
  • 96
    • 20444428352 scopus 로고    scopus 로고
    • A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA
    • Yasukawa T., Yang M.Y., Jacobs H.T., and Holt I.J. A bidirectional origin of replication maps to the major noncoding region of human mitochondrial DNA. Mol. Cell 18 (2005) 651-662
    • (2005) Mol. Cell , vol.18 , pp. 651-662
    • Yasukawa, T.1    Yang, M.Y.2    Jacobs, H.T.3    Holt, I.J.4


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