4-Hydroxynonenal, a product of oxidative stress, leads to an antioxidant response in optic nerve head astrocytes

Experimental Eye Research

Volumn 84, Issue 3, 2007, Pages 444-454

  Malone, P E ^a,b   Hernandez, M R ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

astrocytes; HNE; lipid peroxidation; optic nerve; oxidative stress

Indexed keywords

4 HYDROXYNONENAL; ALDO KETO REDUCTASE 1C FAMILY MEMBER 1; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE A4; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXIDOREDUCTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DETOXIFICATION; DOSE RESPONSE; DOSE TIME EFFECT RELATION; ENZYME ACTIVE SITE; HUMAN; HUMAN TISSUE; LIPID PEROXIDATION; MALE; NUCLEOTIDE SEQUENCE; ONCOGENE C FOS; OPTIC NERVE; OXIDATIVE STRESS; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ADULT; AGED; AGED, 80 AND OVER; ALDEHYDES; ANTIBODIES, MONOCLONAL; ANTIOXIDANTS; ASTROCYTES; BIOLOGICAL MARKERS; CELL SURVIVAL; CELLS, CULTURED; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GLUTATHIONE; HUMANS; MIDDLE AGED; NF-KAPPA B; OPTIC DISK; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-FOS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAINING AND LABELING; TRANSCRIPTION FACTORS;

EID: 33846818874     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2006.10.020     Document Type: Article

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