Apoptosis induced by persistent single-strand breaks in mitochondrial genome: Critical role of EXOG (5′-exo/endonuclease) in their repair

Journal of Biological Chemistry

Volumn 286, Issue 37, 2011, Pages 31975-31983

  Tann, Anne W ^a   Boldogh, Istvan ^a   Meiss, Gregor ^b   Qian, Wei ^c   Van Houten, Bennett ^c   Mitra, Sankar ^a   Szczesny, Bartosz ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOTIC SIGNALING; MAMMALIAN CELLS; MITOCHONDRIAL GENOMES; NUCLEAR GENOMES; REACTIVE OXYGEN SPECIES; REPAIR PATHWAYS; SINGLE-STRAND BREAKS;

BYPRODUCTS; CELL DEATH; MAMMALS; MITOCHONDRIA; REPAIR;

GENES;

DEOXYRIBOSE; ENDONUCLEASE; EXONUCLEASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

5' UNTRANSLATED REGION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXCISION REPAIR; HUMAN; HUMAN CELL; MAMMAL CELL; MITOCHONDRIAL GENOME; PRIORITY JOURNAL; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; SINGLE STRANDED DNA BREAK;

APOPTOSIS; DNA BREAKS, SINGLE-STRANDED; DNA REPAIR; DNA, MITOCHONDRIAL; EXONUCLEASES; GENOME, MITOCHONDRIAL; HELA CELLS; HUMANS; MITOCHONDRIAL PROTEINS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 80052698492     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.215715     Document Type: Article

References (73)

1. Robin, E. D., and Wong, R. (1988) J. Cell. Physiol. 136, 507-513
2. Miller, F. J., Rosenfeldt, F. L., Zhang, C., Linnane, A. W., and Nagley, P. (2003) Nucleic Acids Res. 31, e61
3. Anderson, S., Bankier, A. T., Barrell, B. G., de Bruijn, M. H., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., Sanger, F., Schreier, P. H., Smith, A. J., Staden, R., and Young, I. G. (1981) Nature 290, 457-465
4. Turrens, J. F. (2003) J. Physiol. 552, 335-344
5. Staniek, K., and Nohl, H. (2000) Biochim. Biophys. Acta 1460, 268-275
6. St-Pierre, J., Buckingham, J. A., Roebuck, S. J., and Brand, M. D. (2002) J. Biol. Chem. 277, 44784-44790
7. Cadenas, E., and Davies, K. J. (2000) Free Radic. Biol. Med. 29, 222-230
8. Wallace, S. S. (2002) Free Radic. Biol. Med. 33, 1-14
9. Caldecott, K. W. (2008) Nat. Rev. Genet. 9, 619-631
10. Pesole, G., Gissi, C., De Chirico, A., and Saccone, C. (1999) J. Mol. Evol. 48, 427-434
11. Almeida, K. H., and Sobol, R. W. (2007) DNA Repair 6, 695-711
12. Fortini, P., and Dogliotti, E. (2007) DNA Repair 6, 398-409
13. Hegde, M. L., Hazra, T. K., and Mitra, S. (2008) Cell Res. 18, 27-47
14. Longley, M. J., Prasad, R., Srivastava, D. K., Wilson, S. H., and Copeland, W. C. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 12244-12248
15. Liu, Y., Kao, H. I., and Bambara, R. A. (2004) Annu. Rev. Biochem. 73, 589-615
16. Pinz, K. G., and Bogenhagen, D. F. (1998) Mol. Cell. Biol. 18, 1257-1265
17. Stierum, R. H., Dianov, G. L., and Bohr, V. A. (1999) Nucleic Acids Res. 27, 3712-3719
18. Szczesny, B., Tann, A. W., Longley, M. J., Copeland, W. C., and Mitra, S. (2008) J. Biol. Chem. 283, 26349-26356
19. Liu, P., Qian, L., Sung, J. S., de Souza-Pinto, N. C., Zheng, L., Bogenhagen, D. F., Bohr, V. A., Wilson, D. M., 3rd, Shen, B., and Demple, B. (2008) Mol. Cell. Biol. 28, 4975-4987
20. Akbari, M., Visnes, T., Krokan, H. E., and Otterlei, M. (2008) DNA Repair 7, 605-616
21. Zheng, L., Zhou, M., Guo, Z., Lu, H., Qian, L., Dai, H., Qiu, J., Yakubovskaya, E., Bogenhagen, D. F., Demple, B., and Shen, B. (2008) Mol. Cell 32, 325-336
22. Cymerman, I. A., Chung, I., Beckmann, B. M., Bujnicki, J. M., and Meiss, G. (2008) Nucleic Acids Res. 36, 1369-1379
23. Marchetti, P., Susin, S. A., Decaudin, D., Gamen, S., Castedo, M., Hirsch, T., Zamzami, N., Naval, J., Senik, A., and Kroemer, G. (1996) Cancer Res. 56, 2033-2038
24. Szczesny, B., Tann, A. W., and Mitra, S. (2010) Mech. Ageing Dev. 131, 330-337
25. Ramana, C. V., Boldogh, I., Izumi, T., and Mitra, S. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 5061-5066
26. Qian, W., and Van Houten, B. (2010) Methods 51, 452-457
27. Santos, J. H., Meyer, J. N., Mandavilli, B. S., and Van Houten, B. (2006) Methods Mol. Biol. 314, 183-199
28. Das, A., Wiederhold, L., Leppard, J. B., Kedar, P., Prasad, R., Wang, H., Boldogh, I., Karimi-Busheri, F., Weinfeld, M., Tomkinson, A. E., Wilson, S. H., Mitra, S., and Hazra, T. K. (2006) DNA Repair 5, 1439-1448
29. Izumi, T., and Mitra, S. (1998) Carcinogenesis 19, 525-527
30. Kieper, J., Lauber, C., Gimadutdinow, O., Urbańska, A., Cymerman, I., Ghosh, M., Szczesny, B., and Meiss, G. (2010) Protein Exp. Purif. 73, 99-106
31. Patel, V. A., Longacre, A., Hsiao, K., Fan, H., Meng, F., Mitchell, J. E., Rauch, J., Ucker, D. S., and Levine, J. S. (2006) J. Biol. Chem. 281, 4663-4670
32. Büttner, S., Eisenberg, T., Carmona-Gutierrez, D., Ruli, D., Knauer, H., Ruckenstuhl, C., Sigrist, C., Wissing, S., Kollroser, M., Fröhlich, K. U., Sigrist, S., and Madeo, F. (2007) Mol. Cell 25, 233-246
33. Falkenberg, M., Larsson, N. G., and Gustafsson, C. M. (2007) Annu. Rev. Biochem. 76, 679-699
34. Lizard, G., Miguet, C., Gueldry, S., Monier, S., and Gambert, P. (1997) Ann. Pathol. 17, 61-66
35. Taylor, R. C., Cullen, S. P., and Martin, S. J. (2008) Nat. Rev. Mol. Cell Biol. 9, 231-241
36. Tait, S. W., and Green, D. R. (2010) Nat. Rev. Mol. Cell Biol. 11, 621-632
37. Bratton, S. B., Walker, G., Srinivasula, S. M., Sun, X. M., Butterworth, M., Alnemri, E. S., and Cohen, G. M. (2001) EMBO J. 20, 998-1009
38. Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., and Lazebnik, Y. A., et al. (1995) Nature 376, 37-43
39. Boulares, A. H., Yakovlev, A. G., Ivanova, V., Stoica, B. A., Wang, G., Iyer, S., and Smulson, M. (1999) J. Biol. Chem. 274, 22932-22940
40. Kroemer, G., Zamzami, N., and Susin, S. A. (1997) Immunol. Today 18, 44-51
41. Yang, X. H., Sladek, T. L., Liu, X., Butler, B. R., Froelich, C. J., and Thor, A. D. (2001) Cancer Res. 61, 348-354
42. Yang, X. H., Edgerton, S., and Thor, A. D. (2005) Int. J. Oncol. 26, 1675-1680
43. Meyer, J. N. (2010) Ecotoxicology 19, 804-811
44. Singh, N. P., McCoy, M. T., Tice, R. R., and Schneider, E. L. (1988) Exp. Cell Res. 175, 184-191
45. Shen, B., Singh, P., Liu, R., Qiu, J., Zheng, L., Finger, L. D., and Alas, S. (2005) BioEssays 27, 717-729
46. Panduri, V., Weitzman, S. A., Chandel, N. S., and Kamp, D. W. (2004) Am. J. Physiol. Lung Cell. Mol. Physiol. 286, L1220-L1227
47. Huang, K. J., Ku, C. C., and Lehman, I. R. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 8995-9000
48. Budd, M. E., and Campbell, J. L. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 7642-7646
49. Bae, S. H., and Seo, Y. S. (2000) J. Biol. Chem. 275, 38022-38031
50. Budd, M. E., and Campbell, J. L. (1997) Mol. Cell. Biol. 17, 2136-2142
51. Masuda-Sasa, T., Imamura, O., and Campbell, J. L. (2006) Nucleic Acids Res. 34, 1865-1875
52. Kim, J. H., Kim, H. D., Ryu, G. H., Kim, D. H., Hurwitz, J., and Seo, Y. S. (2006) Nucleic Acids Res. 34, 1854-1864
53. Duxin, J. P., Dao, B., Martinsson, P., Rajala, N., Guittat, L., Campbell, J. L., Spelbrink, J. N., and Stewart, S. A. (2009) Mol. Cell. Biol. 29, 4274-4282
54. Arai, T., Kelly, V. P., Minowa, O., Noda, T., and Nishimura, S. (2006) Toxicology 221, 179-186
55. Nilsen, H., Rosewell, I., Robins, P., Skjelbred, C. F., Andersen, S., Slupphaug, G., Daly, G., Krokan, H. E., Lindahl, T., and Barnes, D. E. (2000) Mol. Cell 5, 1059-1065
56. Takao, M., Kanno, S., Shiromoto, T., Hasegawa, R., Ide, H., Ikeda, S., Sarker, A. H., Seki, S., Xing, J. Z., Le, X. C., Weinfeld, M., Kobayashi, K., Miyazaki, J., Muijtjens, M., Hoeijmakers, J. H., van der Horst, G., Yasui, A., and Sarker, A. H. (2002) EMBO J. 21, 3486-3493
57. Vartanian, V., Lowell, B., Minko, I. G., Wood, T. G., Ceci, J. D., George, S., Ballinger, S. W., Corless, C. L., McCullough, A. K., and Lloyd, R. S. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 1864-1869
58. Jang, Y. C., and Remmen, V. H. (2009) Exp. Gerontol. 44, 256-260
59. Pérez, V. I., Bokov, A., Van Remmen, H., Mele, J., Ran, Q., Ikeno, Y., and Richardson, A. (2009) Biochim. Biophys. Acta 1790, 1005-1014
60. Hance, N., Ekstrand, M. I., and Trifunovic, A. (2005) Hum. Mol. Genet. 14, 1775-1783
61. Puebla-Osorio, N., Lacey, D. B., Alt, F. W., and Zhu, C. (2006) Mol. Cell. Biol. 26, 3935-3941
62. Kucherlapati, M., Yang, K., Kuraguchi, M., Zhao, J., Lia, M., Heyer, J., Kane, M. F., Fan, K., Russell, R., Brown, A. M., Kneitz, B., Edelmann, W., Kolodner, R. D., Lipkin, M., and Kucherlapati, R. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 9924-9929
63. Izumi, T., Brown, D. B., Naidu, C. V., Bhakat, K. K., Macinnes, M. A., Saito, H., Chen, D. J., and Mitra, S. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 5739-5743
64. Appleby, R. D., Porteous, W. K., Hughes, G., James, A. M., Shannon, D., Wei, Y. H., and Murphy, M. P. (1999) Eur. J. Biochem. 262, 108-116
65. Buchet, K., and Godinot, C. (1998) J. Biol. Chem. 273, 22983-22989
66. Stuart, J. A., Hashiguchi, K., Wilson, D. M., 3rd, Copeland, W. C., Souza- Pinto, N. C., and Bohr, V. A. (2004) Nucleic Acids Res. 32, 2181-2192
67. Abraham, R. T. (2001) Genes Dev. 15, 2177-2196
68. Harper, J. W., and Elledge, S. J. (2007) Mol. Cell 28, 739-745
69. Jackson, S. P., and Bartek, J. (2009) Nature 461, 1071-1078
70. Bartek, J., and Lukas, J. (2003) Cancer Cell 3, 421-429
71. Kastan, M. B., and Bartek, J. (2004) Nature 432, 316-323
72. Shiloh, Y. (2003) Nat. Rev. Cancer 3, 155-168
73. Koczor, C. A., Shokolenko, I. N., Boyd, A. K., Balk, S. P., Wilson, G. L., and Ledoux, S. P. (2009) J. Biol. Chem. 284, 36191-36201