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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 6, 2014, Pages 1605-1610

Synthesis, antileishmanial activity and docking study of N′-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl) acetohydrazides

(7) Sangshetti, Jaiprakash N a Shaikh, Rehan I a Khan, Firoz A Kalam a Patil, Rajendra H b Marathe, Sayali D b Gade, Wasudev N b Shinde, Devanand B c

a Y B CHAVAN COLLEGE OF PHARMACY (India)

b UNIVERSITY OF PUNE (India)

c DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY (India)

Author keywords

ADME properties; Antileishmanial activity; Antimicrobial activity; Docking study; L. donovani promastigotes; Thieno 3,2 c pyridine

Indexed keywords

ACETOHYDRAZIDE; AMPICILLIN; CIPROFLOXACIN; FLUCONAZOLE; MICONAZOLE; OXIDOREDUCTASE; PTERIDINE REDUCTASE 1; STIBOGLUCONATE SODIUM; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; LEISHMANIA DONOVANI; MOLECULAR DOCKING; NONHUMAN; SUBSTITUTION REACTION;

LEISHMANIA DONOVANI;

ADME PROPERTIES; ANTILEISHMANIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; DOCKING STUDY; L. DONOVANI PROMASTIGOTES; THIENO[3,2-C]PYRIDINE;

ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS; ANTIPROTOZOAL AGENTS; BENZYLIDENE COMPOUNDS; BINDING SITES; DRUG DESIGN; HALF-LIFE; HYDRAZINES; LEISHMANIA DONOVANI; MICROBIAL SENSITIVITY TESTS; MOLECULAR DOCKING SIMULATION; OXIDOREDUCTASES; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; PYRIDINES;

EID: 84895783137 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2014.01.035 Document Type: Article

Times cited : (33)

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