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Volumn 19, Issue 15, 2011, Pages 4413-4420
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Design, synthesis and biological evaluation of urea derivatives from o-hydroxybenzylamines and phenylisocyanate as potential FabH inhibitors
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Author keywords
Antibacterial; FabH; Inhibitors; o Hydroxybenzylamines; Urea derivatives
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Indexed keywords
1 (5 BROMO 2 HYDROXYBENZYL) 1 (2 BROMOPHENYL) 3 PHENYLUREA;
1 (5 BROMO 2 HYDROXYBENZYL) 1 (2 CHLOROPHENYL) 3 PHENYLUREA;
1 (5 BROMO 2 HYDROXYBENZYL) 1 (2 FLUOROPHENYL) 3 PHENYLUREA;
1 (5 BROMO 2 HYDROXYBENZYL) 1 (4 CHLOROPHENYL) 3 PHENYLUREA;
1 (5 BROMO 2 HYDROXYBENZYL) 1 (4 FLUOROPHENYL) 3 PHENYLUREA;
2,4 DIBROMO 6 [(PARA TOLYLAMINO)METHYL]PHENOL;
2,4 DIBROMO 6 [[(2 BROMOPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(2 CHLOROPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(2 FLUOROPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(4 BROMOPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(4 CHLOROPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(4 FLUOROPHENYL)AMINO]METHYL]PHENOL;
2,4 DIBROMO 6 [[(4 METHOXYPHENYL)AMINO]METHYL]PHENOL;
3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE;
3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE III INHIBITOR;
4 BROMO 2 [(PARA TOLYLAMINO)METHYL]PHENOL;
4 BROMO 2 [[(2 BROMOPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(2 CHLOROPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(2 FLUOROPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(4 BROMOPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(4 CHLOROPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(4 FLUOROPHENYL)AMINO]METHYL]PHENOL;
4 BROMO 2 [[(4 METHOXYPHENYL)AMINO]METHYL]PHENOL;
BENZYLAMINE DERIVATIVE;
ENZYME INHIBITOR;
KANAMYCIN B;
ORTHO HYDROXYBENZYLAMINE DERIVATIVE;
PHENYL ISOCYANATE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
UREA DERIVATIVE;
ANTIBACTERIAL ACTIVITY;
ARTICLE;
BACILLUS SUBTILIS;
BINDING AFFINITY;
CHEMICAL BINDING;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
DRUG DESIGN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SYNTHESIS;
DRUG TARGETING;
ENZYME INHIBITION;
ENZYME STRUCTURE;
ESCHERICHIA COLI;
MINIMUM INHIBITORY CONCENTRATION;
MOLECULAR DOCKING;
NONHUMAN;
PSEUDOMONAS FLUORESCENS;
STAPHYLOCOCCUS AUREUS;
STRUCTURE ACTIVITY RELATION;
X RAY CRYSTALLOGRAPHY;
3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE;
ANTI-BACTERIAL AGENTS;
BACTERIA;
BACTERIAL INFECTIONS;
DRUG DESIGN;
ENZYME INHIBITORS;
ESCHERICHIA COLI;
ESCHERICHIA COLI INFECTIONS;
GRAM-NEGATIVE BACTERIA;
HUMANS;
MICROBIAL SENSITIVITY TESTS;
MODELS, MOLECULAR;
PROTEIN BINDING;
UREA;
ESCHERICHIA COLI;
NEGIBACTERIA;
POSIBACTERIA;
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EID: 79960561354
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2011.06.049 Document Type: Article |
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Times cited : (32)
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References (31)
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