One pot synthesis and SAR of some novel 3-substituted 5,6-diphenyl-1,2,4-triazines as antifungal agents

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 2, 2010, Pages 742-745

  Sangshetti, Jaiprakash N ^a   Shinde, Devanand B ^a  

^a DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY   (India)

Author keywords

1,2,3 Triazole; 1,2,4 Triazines; Hydrazides; MIC values; One pot synthesis; Piperidine; SAR

Indexed keywords

ALCOHOL; AMMONIUM ACETATE; ANTIFUNGAL AGENT; FLUCONAZOLE; MICONAZOLE; TRIAZINE DERIVATIVE; WATER;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; CATALYST; CHEMICAL REACTION; CRYPTOCOCCUS NEOFORMANS; DRUG STRUCTURE; FUSARIUM OXYSPORUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; CATALYSIS; FLUCONAZOLE; MICONAZOLE; MICROBIAL SENSITIVITY TESTS; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZINES; ZIRCONIUM;

ASPERGILLUS NIGER; CANDIDA ALBICANS; FILOBASIDIELLA NEOFORMANS; FUSARIUM OXYSPORUM;

EID: 72249121417     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.11.048     Document Type: Article

References (30)

1. Negwer M. Organisch-Chemische Arzneimittel undihre Synonyma (1987), Akademie, Berlin
2. Sidwell R.W., Dixon G.J., Sellers S.M., and Schabel F.M. Appl. Microbiol. 16 (1968) 370
3. Falke D., and Rada B. Acta Virol. 14 (1970) 115
4. Creasey W.A., Fink M.E., Handschumacker R.E., and Calabresi P. Cancer Res. 23 (1963) 44
5. Walters T.R., Aur R.J.A., Hernandez K., Vietti T., and Pinkel D. Cancer 29 (1972) 1057
6. Matolcsy G. Acta Phytopathol. 1 (1966) 245
7. Diana P., Barraja P., Lauria A., Montalbano A., Almerico A.M., Dattolo G., and Cirrincione G. Eur. J. Med. Chem. 37 (2002) 267
8. Zhao Z., Leister W.H., Strauss K.A., Wisnoski D.D., and Lindsley C.W. Tetrahedron Lett. 44 (2003) 1123
9. Passannanti A., Diana P., Barraja P., Mingoia F., Lauria A., and Cirrincione G. Heterocycles 48 (1998) 1229
10. Chen M.D., Lu S.J., Yuag G.P., Yang S.Y., and Du X.L. Heterocycl. Commun. 6 (2000) 421
11. Sherement E.A., Tomanov R.I., Trukhin E.V., and Berestovitskaya V.M. Russ. J. Org. Chem. 40 (2004) 594
12. Holla B.S., Mahalinga M., Karthikeyan M.S., Poojary B., Mohammed Akberali P., and Kumari N.S. Eur. J. Med. Chem. 40 (2005) 1173
13. Genin M.J., Allwine D.A., Anderson D.J., Barbachyn M.R., Emmert D.E., Garmon S.A., Graber D.R., Grega K.C., Hester J.B., Hutchinson D.K., Morris J., Reischer R.J., Ford C.W., Zurenko G.E., Hamel J.C., Schaadt R.D., Stapert D.B., and Yagi H. J. Med. Chem. 43 (2000) 953
14. André, A.; Jean, M. (Roussel-UCLAF) Ger. Offen, 1815467, 24 July 1969.
15. Banu K.M., Dinakar A., and Ananthanarayanan C. Indian J. Pharm. Sci. 4 (1999) 202
16. Meier, R. EP, 1992,62; eidem, US, 4789680, 1986.
17. Jilino M., and Stevens F.G. J. Chem. Soc., Perkin Trans. 1 (1998) 1677
18. Velarquez S., Alvarez R., Perez C., Gago F., De C., Balzarini J., and Camarasa M.J. Antiviral Chem. Chemother. 9 (1998) 481
19. Danoun S., Baziard-Mouysset G., Stigliani J., Payard M., Selkti M., and Tomas V.A. Heterocycl. Commun. 4 (1998) 45
20. Biagi G., Calderone V., Giorgi I., Livi O., Martinotti E., Martelli A., and Nardi A. Farmaco (2004) 59397
21. Hou, D. R.; Alam, S.; Kuan, T. C.; Ramanathan, M.; Lin, T. P.; Hung M. S. Bioorg. Med. Chem. Lett., in press.
22. Gill C., Jadhav G., Shaikh M., Kale R., Ghawalkar A., Nagargoje D., and Shiradkar M. Bioorg. Med. Chem. Lett. 18 (2008) 6244
23. Nagawade R.R., Khanna V.V., Bhagwat S.S., and Shinde D.B. Eur. J. Med. Chem. 40 (2005) 1325-1330
24. Kokare N.D., Sangshetti J.N., and Shinde D.B. Synthesis 18 (2007) 2829
25. Sangshetti J.N., Kokare N.D., and Shinde D.B. J. Heterocycl. Chem. 45 (2008) 1191
26. Sangshetti, J. N.; Nagawade, R. R.; Shinde, D. B. Bioorg. Med. Chem. Lett., in press.
27. Greenwood D., Slack R.C.B., and Peutherer J.F. Medical Microbiology. 14th ed. Vol. 1 (1992), ELBS, London
28. Duraiswamy B., Mishra S.K., Subhashini V., Dhanraj S.A., and Suresh B. Indian J. Pharm. Sci. 68 (2006) 389
29. Saundane A.R., Rudresh K., Satynarayan N.D., and Hiremath S.P. Indian J. Pharm. Sci. 60 (1989) 379
30. Therese K.L., Bagylaxmi R., Madhavan H.N., and Deepa P. Indian J. Med. Microbiol. 24 (2006) 273-279