Synthesis of some novel 3-(1-(1-substitutedpiperidin-4-yl)-1H-1,2,3- triazol-4-yl)-5-substituted phenyl-1,2,4-oxadiazoles as antifungal agents

European Journal of Medicinal Chemistry

Volumn 46, Issue 4, 2011, Pages 1040-1044

  Sangshetti, Jaiprakash N ^a   Shinde, Devanand B ^a  

^a DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY   (India)

Author keywords

1,2,3 Triazole; 1,2,4 Oxadiazole; Amidoxime; Antifungal activity; MIC values; Piperidine; SAR

Indexed keywords

(4 CHLOROPHENYL)[4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]METHANONE; 1 [4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]BUTAN 1 ONE; 1 [4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]ETHANONE; 1 [4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]PROPAN 1 ONE; 1 [4 [4 [5 (4 CHLOROPHENYL) 1,2,4 OXADIAZOL 3 YL] 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]ETHANONE; 1 [4 [4 [5 (4 CHLOROPHENYL) 1,2,4 OXADIAZOL 3 YL] 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]PROPAN 1 ONE; 1,2,4 OXADIAZOLE DERIVATIVE; 3 [1 (1 BENZYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 5 PHENYL 1,2,4 OXADIAZOLE; 3 [1 (1 ETHYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 5 PHENYL 1,2,4 OXADIAZOLE; 3 [1 (1 METHYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 5 PHENYL 1,2,4 OXADIAZOLE; 3 [1 [1 (METHYLSULFONYL)PIPERIDIN 4 YL] 1H 1,2,3 TRIAZOL 4 YL] 5 PHENYL 1,2,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 3 [1 (1 ETHYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 1,2,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 3 [1 (1 METHYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 1,2,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 3 [1 [1 (METHYLSULFONYL)PIPERIDIN 4 YL] 1H 1,2,3 TRIAZOL 4 YL] 1,2,4 OXADIAZOLE; 5 PHENYL 3 [1 (1 TOSYLPIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 1,2,4 OXADIAZOLE; 5 PHENYL 3 [1 (PIPERIDIN 4 YL) 1H 1,2,3 TRIAZOL 4 YL] 1,2,4 OXADIAZOLE; [4 [4 [5 (4 CHLOROPHENYL) 1,2,4 OXADIAZOL 3 YL] 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1YL](PHENYL)METHANONE; FLUCONAZOLE; MICONAZOLE; PHENYL[4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL 1 YL]PIPERIDIN 1 YL]METHANONE; TERT BUTYL 4 [4 (5 PHENYL 1,2,4 OXADIAZOL 3 YL) 1H 1,2,3 TRIAZOL YL]PIPERIDINE 1 CARBOXYLATE; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS NIGER; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG STRUCTURE; DRUG SYNTHESIS; FUSARIUM OXYSPORUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; BENZOIC ACIDS; CARBONATES; FUNGI; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; OXADIAZOLES; POTASSIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 79952282888     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.01.015     Document Type: Article

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