Structure of recombinant Leishmania donovani pteridine reductase reveals a disordered active site

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 67, Issue 1, 2011, Pages 33-37

  Barrack, Keri L ^a   Tulloch, Lindsay B ^a,b   Burke, Lynsey Ann ^a   Fyfe, Paul K ^a   Hunter, William N ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

antifolates; Leishmania; pteridine reductase; pterins; Trypanosoma

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PROTOZOAL PROTEIN; PTERIDINE REDUCTASE; RECOMBINANT PROTEIN;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; HUMAN; LEISHMANIA DONOVANI; MOLECULAR GENETICS; PROTEIN QUATERNARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; HUMANS; LEISHMANIA DONOVANI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NADP; OXIDOREDUCTASES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; X-RAY DIFFRACTION;

LEISHMANIA DONOVANI; PROTOZOA; TRYPANOSOMA;

EID: 78651090573     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S174430911004724X     Document Type: Article

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