Chemoresistance to concanamycin A1 in human oral squamous cell carcinoma is attenuated by an HDAC inhibitor partly via suppression of Bcl-2 expression

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Kiyoshima, Tamotsu ^a   Yoshida, Hisato ^a   Wada, Hiroko ^a   Nagata, Kengo ^a   Fujiwara, Hiroaki ^a   Kihara, Makiko ^a   Hasegawa, Kana ^a   Someya, Hirotaka ^a   Sakai, Hidetaka ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; CONCANAMYCIN A1; HISTONE DEACETYLASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; RED FLUORESCENT PROTEIN; STAT3 PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VORINOSTAT; CONCANAMYCIN A; MACROLIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ACIDIFICATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CELL LEVEL; CELL ORGANELLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME REPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUTH SQUAMOUS CELL CARCINOMA; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; CELL SURVIVAL; CYTOPLASM VESICLE; DRUG EFFECTS; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUTH TUMOR; PH; PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYTOPLASMIC VESICLES; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; MACROLIDES; MOUTH NEOPLASMS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84894281739     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080998     Document Type: Article

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