Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells

Biochemical and Biophysical Research Communications

Volumn 382, Issue 2, 2009, Pages 451-456

  Wu, Ya Chun ^a,b   Wu, William Ka Kei ^b   Li, Youming ^a   Yu, Le ^b   Li, Zhi Jie ^b   Wong, Clover Ching Man ^b   Li, Hai Tao ^b   Sung, Joseph Jao Yiu ^b   Cho, Chi Hin ^b  

^a First Affiliated Hospital   (China)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Bafilomycin A1; Colon cancer; Macroautophagy; Proliferation

Indexed keywords

BAFILOMYCIN A1; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYCLIN D1; CYCLIN E; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P21; STRESS ACTIVATED PROTEIN KINASE;

ACIDIFICATION; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; LYSOSOME; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UPREGULATION;

APOPTOSIS; AUTOPHAGY; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOPLASMIC VESICLES; ENZYME INHIBITORS; HUMANS; MACROLIDES; MICROTUBULE-ASSOCIATED PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES;

EID: 63349098256     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.051     Document Type: Article

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