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Volumn 106, Issue 4, 2012, Pages 711-718

The BH3 mimetic HA14-1 enhances 5-fluorouracil-induced autophagy and type II cell death in oesophageal cancer cells

Author keywords

apoptosis; autophagy; BH3 mimetic; cell death; HA14 1; oesophageal cancer

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; BH3 PROTEIN; FLUOROURACIL; PROTEIN NOXA;

EID: 84856860371     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2011.604     Document Type: Article
Times cited : (10)

References (32)
  • 1
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • DOI 10.1038/sj.onc.1210220, PII 1210220
    • Adams JM, Cory S (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26: 1324-1337 (Pubitemid 46328466)
    • (2007) Oncogene , vol.26 , Issue.9 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 2
    • 36849088609 scopus 로고    scopus 로고
    • Growth arrest and autophagy are required for salivary gland cell degradation in drosophila
    • DOI 10.1016/j.cell.2007.10.048, PII S009286740701402X
    • Berry DL, Baehrecke EH (2007) Growth arrest and autophagy are required for salivary gland cell degradation in Drosophila. Cell 131: 1137-1148 (Pubitemid 350235023)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1137-1148
    • Berry, D.L.1    Baehrecke, E.H.2
  • 3
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke PG (1990) Developmental cell death: Morphological diversity and multiple mechanisms. Anat Embryol (Berl) 181: 195-213 (Pubitemid 20153523)
    • (1990) Anatomy and Embryology , vol.181 , Issue.3 , pp. 195-213
    • Clarke, P.G.H.1
  • 5
    • 74049125266 scopus 로고    scopus 로고
    • BH3-only proteins: The death-puppeteer's wires
    • Ghiotto F, Fais F, Bruno S (2010) BH3-only proteins: The death-puppeteer's wires. Cytometry A 77: 11-21
    • (2010) Cytometry A , vol.77 , pp. 11-21
    • Ghiotto, F.1    Fais, F.2    Bruno, S.3
  • 7
    • 79958276489 scopus 로고    scopus 로고
    • GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy
    • Heidari N, Hicks MA, Harada H (2010) GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy. Cell Death Dis 1: E76
    • (2010) Cell Death Dis , vol.1
    • Heidari, N.1    Hicks, M.A.2    Harada, H.3
  • 9
    • 63149129655 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: Targeting mitochondrial apoptotic pathways in cancer therapy
    • Kang MH, Reynolds CP (2009) Bcl-2 inhibitors: Targeting mitochondrial apoptotic pathways in cancer therapy. Clin Cancer Res 15: 1126-1132
    • (2009) Clin Cancer Res , vol.15 , pp. 1126-1132
    • Kang, M.H.1    Reynolds, C.P.2
  • 10
    • 33947404375 scopus 로고    scopus 로고
    • Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1
    • DOI 10.1016/j.canlet.2006.09.009, PII S0304383506005374
    • Kessel D, Reiners Jr JJ (2007) Initiation of apoptosis and autophagy by the Bcl-2 antagonist HA14-1. Cancer Lett 249: 294-299 (Pubitemid 46452936)
    • (2007) Cancer Letters , vol.249 , Issue.2 , pp. 294-299
    • Kessel, D.1    Reiners Jr., J.J.2
  • 11
    • 31144476910 scopus 로고    scopus 로고
    • Cathepsins and bid are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin
    • Lamparska-Przybysz M, Gajkowska B, Motyl T (2005) Cathepsins and BID are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin. J Physiol Pharmacol 56(Suppl 3): 159-179 (Pubitemid 43129240)
    • (2005) Journal of Physiology and Pharmacology , vol.56 , Issue.SUPPL. 3 , pp. 159-179
    • Lamparska-Przybysz, M.1    Gajkowska, B.2    Motyl, T.3
  • 12
    • 79952112980 scopus 로고    scopus 로고
    • Drugs targeting Bcl-2 family members as an emerging strategy in cancer
    • Leber B, Geng F, Kale J, Andrews DW (2010) Drugs targeting Bcl-2 family members as an emerging strategy in cancer. Expert Rev Mol Med 12: E28
    • (2010) Expert Rev Mol Med , vol.12
    • Leber, B.1    Geng, F.2    Kale, J.3    Andrews, D.W.4
  • 14
    • 78650170269 scopus 로고    scopus 로고
    • A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum
    • Lian J, Wu X, He F, Karnak D, Tang W, Meng Y, Xiang D, Ji M, Lawrence TS, Xu L (2011) A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum. Cell Death Differ 18: 60-71
    • (2011) Cell Death Differ , vol.18 , pp. 60-71
    • Lian, J.1    Wu, X.2    He, F.3    Karnak, D.4    Tang, W.5    Meng, Y.6    Xiang, D.7    Ji, M.8    Lawrence, T.S.9    Xu, L.10
  • 19
    • 79955676537 scopus 로고    scopus 로고
    • Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics
    • O'Donovan TR, O'Sullivan GC, McKenna SL (2011) Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics. Autophagy 7: 509-524
    • (2011) Autophagy , vol.7 , pp. 509-524
    • O'Donovan, T.R.1    O'Sullivan, G.C.2    McKenna, S.L.3
  • 21
    • 77952525706 scopus 로고    scopus 로고
    • The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells
    • Pan J, Cheng C, Verstovsek S, Chen Q, Jin Y, Cao Q (2010) The BH3-mimetic GX15-070 induces autophagy, potentiates the cytotoxicity of carboplatin and 5-fluorouracil in esophageal carcinoma cells. Cancer Lett 293: 167-174
    • (2010) Cancer Lett , vol.293 , pp. 167-174
    • Pan, J.1    Cheng, C.2    Verstovsek, S.3    Chen, Q.4    Jin, Y.5    Cao, Q.6
  • 22
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: E45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 23
    • 68149153007 scopus 로고    scopus 로고
    • Noxa: At the tip of the balance between life and death
    • Ploner C, Kofler R, Villunger A (2008) Noxa: At the tip of the balance between life and death. Oncogene 27(Suppl 1): S84-S92
    • (2008) Oncogene , vol.27 , Issue.SUPPL. 1
    • Ploner, C.1    Kofler, R.2    Villunger, A.3
  • 24
    • 70949089720 scopus 로고    scopus 로고
    • Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatinresistant ovarian carcinoma cells
    • Simonin K, Brotin E, Dufort S, Dutoit S, Goux D, N'Diaye M, Denoyelle C, Gauduchon P, Poulain L (2009) Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatinresistant ovarian carcinoma cells. Mol Cancer Ther 8: 3162-3170
    • (2009) Mol Cancer Ther , vol.8 , pp. 3162-3170
    • Simonin, K.1    Brotin, E.2    Dufort, S.3    Dutoit, S.4    Goux, D.5    N'Diaye, M.6    Denoyelle, C.7    Gauduchon, P.8    Poulain, L.9
  • 25
    • 37049008863 scopus 로고    scopus 로고
    • SHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell
    • DOI 10.1016/j.canlet.2007.10.012, PII S0304383507004806
    • Tian D, Das SG, Doshi JM, Peng J, Lin J, Xing C (2008) sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell. Cancer Lett 259: 198-208 (Pubitemid 350251643)
    • (2008) Cancer Letters , vol.259 , Issue.2 , pp. 198-208
    • Tian, D.1    Das, S.G.2    Doshi, J.M.3    Peng, J.4    Lin, J.5    Xing, C.6
  • 28
    • 52049090825 scopus 로고    scopus 로고
    • Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death
    • Wan G, Zhaorigetu S, Liu Z, Kaini R, Jiang Z, Hu CA (2008) Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death. J Biol Chem 283: 21540-21549
    • (2008) J Biol Chem , vol.283 , pp. 21540-21549
    • Wan, G.1    Zhaorigetu, S.2    Liu, Z.3    Kaini, R.4    Jiang, Z.5    Hu, C.A.6
  • 30
    • 77955101158 scopus 로고    scopus 로고
    • The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy
    • Wei Y, Kadia T, TongW, Zhang M, Jia Y, Yang H, Hu Y, Tambaro FP, Viallet J, O'Brien S, Garcia-Manero G (2010) The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy. Clin Cancer Res 16: 3923-3932
    • (2010) Clin Cancer Res , vol.16 , pp. 3923-3932
    • Wei, Y.1    Kadia, T.2    TongW Zhang, M.3    Jia, Y.4    Yang, H.5    Hu, Y.6    Tambaro, F.P.7    Viallet, J.8    O'Brien, S.9    Garcia-Manero, G.10
  • 31
    • 33745872296 scopus 로고    scopus 로고
    • Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins
    • DOI 10.1038/sj.cdd.4401937, PII 4401937
    • Zhai D, Jin C, Satterthwait AC, Reed JC (2006) Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins. Cell Death Differ 13: 1419-1421 (Pubitemid 44057478)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1419-1421
    • Zhai, D.1    Jin, C.2    Satterthwait, A.C.3    Reed, J.C.4
  • 32
    • 38549130324 scopus 로고    scopus 로고
    • BH3 mimetics to improve cancer therapy; mechanisms and examples
    • DOI 10.1016/j.drup.2007.08.002, PII S1368764607000593
    • Zhang L, Ming L, Yu J (2007) BH3 mimetics to improve cancer therapy; mechanisms and examples. Drug Resist Update 10: 207-217 (Pubitemid 351163146)
    • (2007) Drug Resistance Updates , vol.10 , Issue.6 , pp. 207-217
    • Zhang, L.1    Ming, L.2    Yu, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.