Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles

European Journal of Medicinal Chemistry

Volumn 74, Issue , 2014, Pages 606-618

  Vitale, Paola ^a   Perrone, Maria Grazia ^a   Malerba, Paola ^a   Lavecchia, Antonio ^b   Scilimati, Antonio ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cyclooxygenase(COX) 1 inhibitors; Diagnostic probes; Diarylisoxazole scaffold; Docking; Ovarian cancer; OVCAR 3 cell line

Indexed keywords

CYCLOOXYGENASE(COX)-1 INHIBITORS; DIAGNOSTIC PROBES; DIARYLISOXAZOLE SCAFFOLD; DOCKING; OVARIAN CANCER; OVCAR-3 CELL LINE;

CELL LINE, TUMOR; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; DRUG DESIGN; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INHIBITORY CONCENTRATION 50; ISOXAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DOCKING SIMULATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84894159469     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.12.023     Document Type: Article

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