-
2
-
-
78049378469
-
The suffocating kidney: Tubulointerstitial hypoxia in endstage renal disease
-
Mimura I, Nangaku M. The suffocating kidney: tubulointerstitial hypoxia in endstage renal disease. Nat Rev Nephrol 2010; 6:667-678.
-
(2010)
Nat Rev Nephrol
, vol.6
, pp. 667-678
-
-
Mimura, I.1
Nangaku, M.2
-
3
-
-
0027210562
-
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
-
Wang GL, Semenza GL. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci U S A 1993; 90:4304-4308.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 4304-4308
-
-
Wang, G.L.1
Semenza, G.L.2
-
5
-
-
84886424419
-
Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress
-
Friederich-Persson M, Thorn E, Hansell P, et al. Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress. Hypertension 2013; 62:914-919.
-
(2013)
Hypertension
, vol.62
, pp. 914-919
-
-
Friederich-Persson, M.1
Thorn, E.2
Hansell, P.3
-
6
-
-
79952391694
-
Tubular injury in a rat model of type 2 diabetes is prevented by metformin: A possible role of HIF-1alpha expression and oxygen metabolism
-
Takiyama Y, Harumi T, Watanabe J, et al. Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1alpha expression and oxygen metabolism. Diabetes 2011; 60:981-992.
-
(2011)
Diabetes
, vol.60
, pp. 981-992
-
-
Takiyama, Y.1
Harumi, T.2
Watanabe, J.3
-
7
-
-
69249118534
-
Association between chronic obstructive pulmonary disease and chronic kidney disease in vascular surgery patients
-
van Gestel YR, Chonchol M, Hoeks SE, et al. Association between chronic obstructive pulmonary disease and chronic kidney disease in vascular surgery patients. Nephrol Dial Transplant 2009; 24:2763-2767.
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 2763-2767
-
-
Van Gestel, Y.R.1
Chonchol, M.2
Hoeks, S.E.3
-
8
-
-
84859925524
-
Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia
-
Nicholl DD, Ahmed SB, Loewen AH, et al. Declining kidney function increases the prevalence of sleep apnea and nocturnal hypoxia. Chest 2012; 141:1422-1430.
-
(2012)
Chest
, vol.141
, pp. 1422-1430
-
-
Nicholl, D.D.1
Ahmed, S.B.2
Loewen, A.H.3
-
9
-
-
84863103078
-
Obstructive sleep apnea syndrome is related to the progression of chronic kidney disease
-
Kanbay A, Buyukoglan H, Ozdogan N, et al. Obstructive sleep apnea syndrome is related to the progression of chronic kidney disease. Int Urol Nephrol 2012; 44:535-539.
-
(2012)
Int Urol Nephrol
, vol.44
, pp. 535-539
-
-
Kanbay, A.1
Buyukoglan, H.2
Ozdogan, N.3
-
10
-
-
41549146602
-
High prevalence of chronic kidney disease among patients with sleep related breathing disorder (SRBD)
-
Iseki K, Tohyama K, Matsumoto T, Nakamura H. High prevalence of chronic kidney disease among patients with sleep related breathing disorder (SRBD). Hypertens Res 2008; 31:249-255.
-
(2008)
Hypertens Res
, vol.31
, pp. 249-255
-
-
Iseki, K.1
Tohyama, K.2
Matsumoto, T.3
Nakamura, H.4
-
11
-
-
59649097117
-
Altitude and all-cause mortality in incident dialysis patients
-
Winkelmayer WC, Liu J, Brookhart MA. Altitude and all-cause mortality in incident dialysis patients. JAMA 2009; 301:508-512.
-
(2009)
JAMA
, vol.301
, pp. 508-512
-
-
Winkelmayer, W.C.1
Liu, J.2
Brookhart, M.A.3
-
13
-
-
84874883086
-
Renal tissue oxygenation in essential hypertension and chronic kidney disease
-
Pruijm M, Hofmann L, Vogt B, et al. Renal tissue oxygenation in essential hypertension and chronic kidney disease. Int J Hypertens 2013; 2013: 696598.
-
(2013)
Int J Hypertens
, vol.2013
, pp. 696598
-
-
Pruijm, M.1
Hofmann, L.2
Vogt, B.3
-
14
-
-
84861651942
-
Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI
-
Yin WJ, Liu F, Li XM, et al. Noninvasive evaluation of renal oxygenation in diabetic nephropathy by BOLD-MRI. Eur J Radiol 2012; 81:1426-1431.
-
(2012)
Eur J Radiol
, vol.81
, pp. 1426-1431
-
-
Yin, W.J.1
Liu, F.2
Li, X.M.3
-
15
-
-
79960957297
-
Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging
-
Inoue T, Kozawa E, Okada H, et al. Noninvasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging. J Am Soc Nephrol 2011; 22:1429-1434.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1429-1434
-
-
Inoue, T.1
Kozawa, E.2
Okada, H.3
-
16
-
-
79952253559
-
Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: Preliminary experience
-
Wang ZJ, Kumar R, Banerjee S, Hsu CY. Blood oxygen level-dependent (BOLD) MRI of diabetic nephropathy: preliminary experience. J Magn Reson Imaging 2011; 33:655-660.
-
(2011)
J Magn Reson Imaging
, vol.33
, pp. 655-660
-
-
Wang, Z.J.1
Kumar, R.2
Banerjee, S.3
Hsu, C.Y.4
-
17
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer NV, Kotch LE, Agani F, et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 1998; 12:149-162.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
-
18
-
-
0344826529
-
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/-mice
-
Scortegagna M, Ding K, Oktay Y, et al. Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/-mice. Nat Genet 2003; 35:331-340.
-
(2003)
Nat Genet
, vol.35
, pp. 331-340
-
-
Scortegagna, M.1
Ding, K.2
Oktay, Y.3
-
19
-
-
34347265260
-
Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): A negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells
-
Makino Y, Uenishi R, Okamoto K, et al. Transcriptional up-regulation of inhibitory PAS domain protein gene expression by hypoxia-inducible factor 1 (HIF-1): a negative feedback regulatory circuit in HIF-1-mediated signaling in hypoxic cells. J Biol Chem 2007; 282:14073-14082.
-
(2007)
J Biol Chem
, vol.282
, pp. 14073-14082
-
-
Makino, Y.1
Uenishi, R.2
Okamoto, K.3
-
20
-
-
33745665335
-
HIF prolyl hydroxylases in the rat; Organ distribution and changes in expression following hypoxia and coronary artery ligation
-
Willam C, Maxwell PH, Nichols L, et al. HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation. J Mol Cell Cardiol 2006; 41:68-77.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 68-77
-
-
Willam, C.1
Maxwell, P.H.2
Nichols, L.3
-
21
-
-
84882252310
-
Hypoxia-inducible factor prolyl 4-hydroxylases: Common and specific roles
-
Myllyharju J, Koivunen P. Hypoxia-inducible factor prolyl 4-hydroxylases: common and specific roles. Biol Chem 2013; 394:435-448.
-
(2013)
Biol Chem
, vol.394
, pp. 435-448
-
-
Myllyharju, J.1
Koivunen, P.2
-
22
-
-
18444380862
-
Expression of hypoxiainducible factor-1alpha and-2alpha in hypoxic and ischemic rat kidneys
-
Rosenberger C, Mandriota S, Jurgensen JS, et al. Expression of hypoxiainducible factor-1alpha and-2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 2002; 13:1721-1732.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
Mandriota, S.2
Jurgensen, J.S.3
-
23
-
-
84872134149
-
Regulation of erythropoiesis by hypoxia-inducible factors
-
Haase VH. Regulation of erythropoiesis by hypoxia-inducible factors. Blood Rev 2013; 27:41-53.
-
(2013)
Blood Rev
, vol.27
, pp. 41-53
-
-
Haase, V.H.1
-
24
-
-
84879037862
-
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation
-
Tan Q, Kerestes H, Percy MJ, et al. Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation. J Biol Chem 2013; 288:17134-17144.
-
(2013)
J Biol Chem
, vol.288
, pp. 17134-17144
-
-
Tan, Q.1
Kerestes, H.2
Percy, M.J.3
-
25
-
-
84885060233
-
Plasticity of renal erythropoietinproducing cells governs fibrosis
-
Souma T, Yamazaki S, Moriguchi T, et al. Plasticity of renal erythropoietinproducing cells governs fibrosis. J Am Soc Nephrol 2013; 24:1599-1616
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 1599-1616
-
-
Souma, T.1
Yamazaki, S.2
Moriguchi, T.3
-
26
-
-
9644291798
-
Hypoxia in renal disease with proteinuria and/ or glomerular hypertension
-
Tanaka T, Miyata T, Inagi R, et al. Hypoxia in renal disease with proteinuria and/ or glomerular hypertension. Am J Pathol 2004; 165:1979-1992.
-
(2004)
Am J Pathol
, vol.165
, pp. 1979-1992
-
-
Tanaka, T.1
Miyata, T.2
Inagi, R.3
-
27
-
-
33646358954
-
High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxiainducible factor/hypoxia- responsible element pathway
-
Katavetin P, Miyata T, Inagi R, et al. High glucose blunts vascular endothelial growth factor response to hypoxia via the oxidative stress-regulated hypoxiainducible factor/hypoxia-responsible element pathway. J Am Soc Nephrol 2006; 17:1405-1413.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1405-1413
-
-
Katavetin, P.1
Miyata, T.2
Inagi, R.3
-
28
-
-
37249086816
-
Adaptation to hypoxia in the diabetic rat kidney
-
Rosenberger C, Khamaisi M, Abassi Z, et al. Adaptation to hypoxia in the diabetic rat kidney. Kidney Int 2008; 73:34-42.
-
(2008)
Kidney Int
, vol.73
, pp. 34-42
-
-
Rosenberger, C.1
Khamaisi, M.2
Abassi, Z.3
-
29
-
-
44849131121
-
Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice
-
Ceradini DJ, Yao D, Grogan RH, et al. Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice. J Biol Chem 2008; 283:10930-10938.
-
(2008)
J Biol Chem
, vol.283
, pp. 10930-10938
-
-
Ceradini, D.J.1
Yao, D.2
Grogan, R.H.3
-
30
-
-
80155151941
-
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner
-
Chiang CK, Tanaka T, Inagi R, et al. Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner. Lab Invest 2011; 91:1564-1571.
-
(2011)
Lab Invest
, vol.91
, pp. 1564-1571
-
-
Chiang, C.K.1
Tanaka, T.2
Inagi, R.3
-
31
-
-
84885154459
-
Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia
-
Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB J 2013; 27:4059-4075.
-
(2013)
FASEB J
, vol.27
, pp. 4059-4075
-
-
Tanaka, T.1
Yamaguchi, J.2
Higashijima, Y.3
Nangaku, M.4
-
32
-
-
65649105473
-
HIF-prolyl hydroxylases in the rat kidney: Physiologic expression patterns and regulation in acute kidney injury
-
Schodel J, Klanke B, Weidemann A, et al. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol 2009; 174:1663-1674.
-
(2009)
Am J Pathol
, vol.174
, pp. 1663-1674
-
-
Schodel, J.1
Klanke, B.2
Weidemann, A.3
-
33
-
-
77958089464
-
Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells
-
Schodel J, Bohr D, Klanke B, et al. Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells. Kidney Int 2010; 78:857-867.
-
(2010)
Kidney Int
, vol.78
, pp. 857-867
-
-
Schodel, J.1
Bohr, D.2
Klanke, B.3
-
34
-
-
25144475141
-
Cobalt promotes angiogenesis via hypoxiainducible factor and protects tubulointerstitium in the remnant kidney model
-
Tanaka T, Kojima I, Ohse T, et al. Cobalt promotes angiogenesis via hypoxiainducible factor and protects tubulointerstitium in the remnant kidney model. Lab Invest 2005; 85:1292-1307.
-
(2005)
Lab Invest
, vol.85
, pp. 1292-1307
-
-
Tanaka, T.1
Kojima, I.2
Ohse, T.3
-
35
-
-
72949106456
-
Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney
-
Song YR,You SJ, Lee YM,et al.Activation of hypoxia-inducible factor attenuates renal injury in rat remnant kidney. Nephrol Dial Transplant 2010; 25:77-85
-
(2010)
Nephrol Dial Transplant
, vol.25
, pp. 77-85
-
-
Song, Y.R.1
You, S.J.2
Lee, Y.M.3
-
36
-
-
32844456187
-
Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis
-
Tanaka T, Matsumoto M, Inagi R, et al. Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis. Kid Int 2005; 68:2714-2725.
-
(2005)
Kid Int
, vol.68
, pp. 2714-2725
-
-
Tanaka, T.1
Matsumoto, M.2
Inagi, R.3
-
37
-
-
84879792763
-
Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase
-
Zhang XL, Yan ZW, Sheng WW, et al. Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase. Mol Cell Biochem 2011; 358:287-295.
-
(2011)
Mol Cell Biochem
, vol.358
, pp. 287-295
-
-
Zhang, X.L.1
Yan, Z.W.2
Sheng, W.W.3
-
38
-
-
84861128230
-
Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury
-
Kobayashi H, Gilbert V, Liu Q, et al. Myeloid cell-derived hypoxia-inducible factor attenuates inflammation in unilateral ureteral obstruction-induced kidney injury. J Immunol 2012; 188:5106-5115.
-
(2012)
J Immunol
, vol.188
, pp. 5106-5115
-
-
Kobayashi, H.1
Gilbert, V.2
Liu, Q.3
-
39
-
-
80555148901
-
Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury
-
Schley G, Klanke B, Schodel J, et al. Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury. J Am Soc Nephrol 2011; 22:2004-2015.
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 2004-2015
-
-
Schley, G.1
Klanke, B.2
Schodel, J.3
-
40
-
-
80054976363
-
Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis
-
Theilig F, Enke AK, Scolari B, et al. Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. Am J Pathol 2011; 179:2177-2188.
-
(2011)
Am J Pathol
, vol.179
, pp. 2177-2188
-
-
Theilig, F.1
Enke, A.K.2
Scolari, B.3
-
41
-
-
84874703083
-
Renal expression of hypoxia inducible factor-1alpha in patients with chronic kidney disease: A clinicopathologic study from nephrectomized kidneys
-
Hung TW, Liou JH, Yeh KT, et al. Renal expression of hypoxia inducible factor-1alpha in patients with chronic kidney disease: a clinicopathologic study from nephrectomized kidneys. Indian J Med Res 2013; 137:102-110.
-
(2013)
Indian J Med Res
, vol.137
, pp. 102-110
-
-
Hung, T.W.1
Liou, J.H.2
Yeh, K.T.3
-
42
-
-
57049135813
-
Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis
-
Kimura K, Iwano M, Higgins DF, et al. Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis. Am J Physiol Renal Physiol 2008; 295:F1023-F1029.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Kimura, K.1
Iwano, M.2
Higgins, D.F.3
-
43
-
-
33748448816
-
Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice
-
Ding M, Cui S, Li C, et al. Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat Med 2006; 12:1081-1087.
-
(2006)
Nat Med
, vol.12
, pp. 1081-1087
-
-
Ding, M.1
Cui, S.2
Li, C.3
-
44
-
-
33750983605
-
Correction of anemia with epoetin alfa in chronic kidney disease
-
Singh AK, Szczech L, Tang KL, et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006; 355:2085-2098.
-
(2006)
N Engl J Med
, vol.355
, pp. 2085-2098
-
-
Singh, A.K.1
Szczech, L.2
Tang, K.L.3
-
45
-
-
33751002326
-
Normalization of hemoglobin level in patients with chronic kidney disease and anemia
-
Drueke TB, Locatelli F, Clyne N, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006; 355:2071-2084.
-
(2006)
N Engl J Med
, vol.355
, pp. 2071-2084
-
-
Drueke, T.B.1
Locatelli, F.2
Clyne, N.3
-
46
-
-
70949108082
-
A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
-
Pfeffer MA, Burdmann EA, Chen CY, et al. A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med 2009; 361:2019-2032.
-
(2009)
N Engl J Med
, vol.361
, pp. 2019-2032
-
-
Pfeffer, M.A.1
Burdmann, E.A.2
Chen, C.Y.3
-
47
-
-
50849110807
-
Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes
-
Szczech LA, Barnhart HX, Inrig JK, et al. Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes. Kidney Int 2008; 74:791-798.
-
(2008)
Kidney Int
, vol.74
, pp. 791-798
-
-
Szczech, L.A.1
Barnhart, H.X.2
Inrig, J.K.3
-
48
-
-
77956704796
-
Erythropoietic response and outcomes in kidney disease and type 2 diabetes
-
Solomon SD, Uno H, Lewis EF, et al. Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med 2010; 363:1146-1155.
-
(2010)
N Engl J Med
, vol.363
, pp. 1146-1155
-
-
Solomon, S.D.1
Uno, H.2
Lewis, E.F.3
-
49
-
-
34447120059
-
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
-
Peyssonnaux C, Zinkernagel AS, Schuepbach RA, et al. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest 2007; 117:1926-1932.
-
(2007)
J Clin Invest
, vol.117
, pp. 1926-1932
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Schuepbach, R.A.3
-
50
-
-
67650531089
-
Genome-wide association of hypoxiainducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
-
Mole DR, Blancher C, Copley RR, et al. Genome-wide association of hypoxiainducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem 2009; 284:16767-16775.
-
(2009)
J Biol Chem
, vol.284
, pp. 16767-16775
-
-
Mole, D.R.1
Blancher, C.2
Copley, R.R.3
-
51
-
-
79959450883
-
High-resolution genomewide mapping of HIF-binding sites by ChIP-seq
-
Schodel J, Oikonomopoulos S, Ragoussis J, et al. High-resolution genomewide mapping of HIF-binding sites by ChIP-seq. Blood 2011; 117:e207-e217.
-
(2011)
Blood
, vol.117
-
-
Schodel, J.1
Oikonomopoulos, S.2
Ragoussis, J.3
-
52
-
-
63449103705
-
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
-
Xia X, Lemieux ME, Li W, et al. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proc Natl Acad Sci U S A 2009; 106:4260-4265.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4260-4265
-
-
Xia, X.1
Lemieux, M.E.2
Li, W.3
-
53
-
-
84878221564
-
Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma
-
Shoji K, Murayama T, Mimura I, et al. Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma. Am J Pathol 2013; 182:2191-2203.
-
(2013)
Am J Pathol
, vol.182
, pp. 2191-2203
-
-
Shoji, K.1
Murayama, T.2
Mimura, I.3
-
54
-
-
84911411686
-
Hypoxia regulates the sperm associated antigen 4 (SPAG4) via HIF, which is expressed in renal clear cell carcinoma and promotes migration and invasion in vitro
-
[Epub ahead of print]
-
Knaup KX, Monti J, Hackenbeck T, et al. Hypoxia regulates the sperm associated antigen 4 (SPAG4) via HIF, which is expressed in renal clear cell carcinoma and promotes migration and invasion in vitro. Mol Carcinog 2013. [Epub ahead of print]
-
(2013)
Mol Carcinog
-
-
Knaup, K.X.1
Monti, J.2
Hackenbeck, T.3
-
55
-
-
73549088729
-
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth
-
Krieg AJ, Rankin EB, Chan D, et al. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth. Mol Cell Biol 2010; 30:344-353.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 344-353
-
-
Krieg, A.J.1
Rankin, E.B.2
Chan, D.3
-
56
-
-
66049156204
-
Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/ profibrotic genes
-
Zager RA, Johnson AC. Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/ profibrotic genes. Am J Physiol Renal Physiol 2009; 296:F1032-F1041.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Zager, R.A.1
Johnson, A.C.2
-
57
-
-
84883527272
-
Novel therapeutic strategy with hypoxiainducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis
-
Mimura I, Tanaka T, Nangaku M. Novel therapeutic strategy with hypoxiainducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis. Semin Nephrol 2013; 33:375-382.
-
(2013)
Semin Nephrol
, vol.33
, pp. 375-382
-
-
Mimura, I.1
Tanaka, T.2
Nangaku, M.3
-
58
-
-
84864627973
-
Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A
-
Mimura I, Nangaku M, Kanki Y, et al. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol Cell Biol 2012; 32:3018-3032.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 3018-3032
-
-
Mimura, I.1
Nangaku, M.2
Kanki, Y.3
-
59
-
-
79955593914
-
MicroRNAs as mediators and therapeutic targets in chronic kidney disease
-
Lorenzen JM, Haller H, Thum T. MicroRNAs as mediators and therapeutic targets in chronic kidney disease. Nat Rev Nephrol 2011; 7:286-294.
-
(2011)
Nat Rev Nephrol
, vol.7
, pp. 286-294
-
-
Lorenzen, J.M.1
Haller, H.2
Thum, T.3
-
60
-
-
84878641501
-
MiR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-alpha activation
-
Fang Y, Yu X, Liu Y, et al. miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-alpha activation. Am J Physiol Renal Physiol 2013; 304:F1274-1282.
-
(2013)
Am J Physiol Renal Physiol
, vol.304
-
-
Fang, Y.1
Yu, X.2
Liu, Y.3
-
61
-
-
84864452770
-
Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells
-
Muratsu-Ikeda S, Nangaku M, Ikeda Y, et al. Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells. PloS ONE 2012; 7:e41462.
-
(2012)
PloS ONE
, vol.7
-
-
Muratsu-Ikeda, S.1
Nangaku, M.2
Ikeda, Y.3
-
62
-
-
79954432699
-
Fetal environment epigenetics and pediatric renal disease
-
Woroniecki R, Gaikwad AB, Susztak K. Fetal environment epigenetics and pediatric renal disease. Pediatr Nephrol 2011; 26:705-711.
-
(2011)
Pediatr Nephrol
, vol.26
, pp. 705-711
-
-
Woroniecki, R.1
Gaikwad, A.B.2
Susztak, K.3
-
63
-
-
84880750873
-
Structure-based drug design for hypoxia-inducible factor prolyl-hydroxylase inhibitors and its therapeutic potential for the treatment of erythropoiesis-stimulating agent-resistant anemia: Raising expectations for exploratory clinical trials
-
Higashijima Y, Tanaka T, Nangaku M. Structure-based drug design for hypoxia-inducible factor prolyl-hydroxylase inhibitors and its therapeutic potential for the treatment of erythropoiesis-stimulating agent-resistant anemia: raising expectations for exploratory clinical trials. Expert Opin Drug Discov 2013; 8:965-976.
-
(2013)
Expert Opin Drug Discov
, vol.8
, pp. 965-976
-
-
Higashijima, Y.1
Tanaka, T.2
Nangaku, M.3
-
64
-
-
84860508117
-
Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury
-
Kapitsinou PP, Jaffe J, Michael M, et al. Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury. Am J Physiol Renal Physiol 2012; 302:F1172-F1179.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
-
-
Kapitsinou, P.P.1
Jaffe, J.2
Michael, M.3
-
65
-
-
84860505643
-
The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
-
Wang Z, Schley G, Turkoglu G, et al. The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment. Nephrol Dial Transplant 2012; 27:929-936.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 929-936
-
-
Wang, Z.1
Schley, G.2
Turkoglu, G.3
-
66
-
-
75849163295
-
Donor treatment with a PHDinhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model
-
Bernhardt WM, Gottmann U, Doyon F, et al. Donor treatment with a PHDinhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model. Proc Natl Acad Sci U S A 2009; 106:21276-21281.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 21276-21281
-
-
Bernhardt, W.M.1
Gottmann, U.2
Doyon, F.3
-
67
-
-
84864612843
-
The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration
-
Yu X, Fang Y, Liu H, et al. The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration. Nephrol Dial Transplant 2012; 27:3110-3119.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 3110-3119
-
-
Yu, X.1
Fang, Y.2
Liu, H.3
-
68
-
-
84865601727
-
Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury
-
Jamadarkhana P, Chaudhary A, Chhipa L, et al. Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury. Am J Nephrol 2012; 36:208-218.
-
(2012)
Am J Nephrol
, vol.36
, pp. 208-218
-
-
Jamadarkhana, P.1
Chaudhary, A.2
Chhipa, L.3
-
69
-
-
65249167552
-
Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation
-
Ma D, Lim T, Xu J, et al. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol 2009; 20:713-720.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 713-720
-
-
Ma, D.1
Lim, T.2
Xu, J.3
-
70
-
-
84894036517
-
Early treatment with xenon protects against the cold ischemia associated with chronic allograft nephropathy in rats
-
[Epub ahead of print]
-
Zhao H, Luo X, Zhou Z, et al. Early treatment with xenon protects against the cold ischemia associated with chronic allograft nephropathy in rats. Kidney Int 2013. [Epub ahead of print]
-
(2013)
Kidney Int
-
-
Zhao, H.1
Luo, X.2
Zhou, Z.3
-
71
-
-
84881375174
-
Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats
-
Zhao H, Watts HR, Chong M, et al. Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats. Am J Transplant 2013; 13:2006-2018.
-
(2013)
Am J Transplant
, vol.13
, pp. 2006-2018
-
-
Zhao, H.1
Watts, H.R.2
Chong, M.3
-
72
-
-
84878490659
-
Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity
-
Jia P, Teng J, Zou J, et al. Intermittent exposure to xenon protects against gentamicin-induced nephrotoxicity. PloS ONE 2013; 8:e64329.
-
(2013)
PloS ONE
, vol.8
-
-
Jia, P.1
Teng, J.2
Zou, J.3
|