Altitude and the risk of cardiovascular events in incident US dialysis patients

Nephrology Dialysis Transplantation

Volumn 27, Issue 6, 2012, Pages 2411-2417

  Winkelmayer, Wolfgang C ^a,b   Hurley, Michael P ^a   Liu, Jun ^b   Brookhart, M Alan ^b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c University of North Carolina at Chapel Hill   (United States)

Author keywords

Elevation; End stage renal disease; Hypoxia; Hypoxia inducible factor; USRDS

Indexed keywords

ADULT; ALTITUDE; AMERICAN INDIAN; ARTICLE; BIOMETRY; CARDIOVASCULAR DEATH; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; FEMALE; GEOGRAPHY; HEART INFARCTION; HEMODIALYSIS PATIENT; HUMAN; HYPOXIA; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PATIENT CODING; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; RACE; SEA LEVEL; STROKE; UNITED STATES;

ADOLESCENT; ADULT; ALTITUDE; CALIFORNIA; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; CAUSE OF DEATH; FEMALE; FOLLOW-UP STUDIES; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PROGNOSIS; RENAL DIALYSIS; SURVIVAL RATE; YOUNG ADULT;

EID: 84861854253     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr681     Document Type: Article

References (39)

1. Winkelmayer WC, Liu J, Brookhart MA. Altitude and all-cause mortality in incident dialysis patients. JAMA 2009; 301: 508-512
2. Brookhart MA, Schneeweiss S, Avorn J et al. The effect of altitude on dosing and response to erythropoietin in ESRD. J Am Soc Nephrol 2008; 19: 1389-1395
3. Brookhart MA, Bradbury BD, Avorn J et al. The effect of altitude change on anemia treatment response in hemodialysis patients. Am J Epidemiol 2011; 173: 768-777
4. Longenecker JC, Coresh J, Klag MJ et al. Validation of comorbid conditions on the end-stage renal disease medical evidence report: the CHOICE study. Choices for Healthy Outcomes in Caring for ESRD. J Am Soc Nephrol 2000; 11: 520-529
5. Kiyota Y, Schneeweiss S, Glynn RJ et al. Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J 2004; 148: 99-104
6. Kurian AK, Cardarelli KM. Racial and ethnic differences in cardiovascular disease risk factors: a systematic review. Ethn Dis 2007; 17: 143-152
7. Winkleby MA, Kraemer HC, Ahn DK et al. Ethnic and socioeconomic differences in cardiovascular disease risk factors: findings for women from the Third National Health and Nutrition Examination Survey, 1988-1994. JAMA 1998; 280: 356-362
8. Sacco RL, Boden-Albala B, Abel G et al. Race-ethnic disparities in the impact of stroke risk factors: the northern Manhattan stroke study. Stroke 2001; 32: 1725-1731
9. US Renal Data System. USRDS 2009 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Vol. 3. 2009. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2009, p. 651
10. de Jager DJ, Grootendorst DC, Jager KJ et al. Cardiovascular and noncardiovascular mortality among patients starting dialysis. JAMA 2009; 302: 1782-1789
11. Mortimer EA Jr, Monson RR, MacMahon B. Reduction in mortality from coronary heart disease in men residing at high altitude. N Engl J Med 1977; 296: 581-585
12. Buechley RW, Key CR, Morris DL et al. Altitude and ischemic heart disease in tricultural New Mexico: an example of confounding. Am J Epidemiol 1979; 109: 663-666
13. Cardiovascular mortality and altitude. Br Med J 1980; 280: 5
14. Longenecker JC, Coresh J, Powe NR et al. Traditional cardiovascular disease risk factors in dialysis patients compared with the general population: the CHOICE Study. J Am Soc Nephrol 2002; 13: 1918-1927
15. Howard BV, Lee ET, Cowan LD et al. Rising tide of cardiovascular disease in American Indians. The Strong Heart Study. Circulation 1999; 99: 2389-2395
16. Becker TM, Wiggins C, Key CR et al. Ischemic heart disease mortality in Hispanics, American Indians, and non-Hispanic whites in New Mexico, 1958-1982. Circulation 1988; 78: 302-309
17. Harwell TS, Oser CS, Okon NJ et al. Defining disparities in cardiovascular disease for American Indians: trends in heart disease and stroke mortality among American Indians and whites in Montana, 1991 to 2000. Circulation 2005; 112: 2263-2267
18. Chi NC, Karliner JS. Molecular determinants of responses to myocardial ischemia/reperfusion injury: focus on hypoxia-inducible and heat shock factors. Cardiovasc Res 2004; 61: 437-447
19. Shohet RV, Garcia JA. Keeping the engine primed: HIF factors as key regulators of cardiac metabolism and angiogenesis during ischemia. J Mol Med 2007; 85: 1309-1315
20. Bernhardt WM, Wiesener MS, Scigalla P et al. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol 2010; 21: 2151-2156
21. Rao M, Pereira BJ. Optimal anemia management reduces cardiovascular morbidity, mortality, and costs in chronic kidney disease. Kidney Int 2005; 68: 1432-1438
22. Zheng ZL, Hwang YH, Kim SK et al. Genetic polymorphisms of hypoxia-inducible factor-1 alpha and cardiovascular disease in hemodialysis patients. Nephron Clin Pract 2009; 113: c104-c111
23. Rey S, Semenza GL. Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling. Cardiovasc Res 2010; 86: 236-242
24. Schultz A, Lavie L, Hochberg I et al. Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation. Circulation 1999; 100: 547-552
25. Chen SM, Li YG, Zhang HX et al. Hypoxia-inducible factor-1alpha induces the coronary collaterals for coronary artery disease. Coron Artery Dis 2008; 19: 173-179
26. Ryter SW, Otterbein LE, Morse D et al. Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance. Mol Cell Biochem 2002; 234-235: 249-263
27. Ockaili R, Natarajan R, Salloum F et al. HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation. Am J Physiol Heart Circ Physiol 2005; 289: H542-H548
28. Date T, Mochizuki S, Belanger AJ et al. Expression of constitutively stable hybrid hypoxia-inducible factor-1alpha protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury. Am J Physiol Cell Physiol 2005; 288: C314-C320
29. Shinmura K, Tang XL, Wang Y et al. Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits. Proc Natl Acad Sci USA 2000; 97: 10197-10202
30. Kido M, Du L, Sullivan CC et al. Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse. J Am Coll Cardiol 2005; 46: 2116-2124
31. Hyvarinen J, Hassinen IE, Sormunen R et al. Hearts of hypoxiainducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury. J Biol Chem 2010; 285: 13646-13657
32. Eckle T, Kohler D, Lehmann R et al. Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning. Circulation 2008; 118: 166-175
33. Huang M, Chan DA, Jia F et al. Short hairpin RNA interference therapy for ischemic heart disease. Circulation 2008; 118: S226-S233
34. Fabsitz R, Feinleib M. Geographic patterns in county mortality rates from cardiovascular diseases. Am J Epidemiol 1980; 111: 315-328
35. Gordon RS Jr, Kahn HA, Forman S. Altitude and CBVD death rates show apparent relationship. Stroke 1977; 8: 274
36. Voors AW, Johnson WD. Altitude and arteriosclerotic heart disease mortality in white residents of 99 of the 100 largest cities in the United States. J Chronic Dis 1979; 32: 157-162
37. Faeh D, Gutzwiller F, Bopp M. Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland. Circulation 2009; 120: 495-501
38. Valenti L, Dongiovanni P, Motta BM et al. Serum hepcidin and macrophage iron correlate with MCP-1 release and vascular damage in patients with metabolic syndrome alterations. Arterioscler Thromb Vasc Biol 2011; 31: 683-690
39. Wolf M, Shah A, Gutierrez O et al. Vitamin D levels and early mortality among incident hemodialysis patients. Kidney Int 2007; 72: 1004-1013