-
1
-
-
82955233407
-
WNK1 promotes PIP2 synthesis to coordinate growth factor and GPCR-Gq signaling
-
An, S. W., Cha, S. K., Yoon, J., Chang, S., Ross, E. M. and Huang, C. L. (2011). WNK1 promotes PIP2 synthesis to coordinate growth factor and GPCR-Gq signaling. Curr. Biol. 21, 1979-1987.
-
(2011)
Curr. Biol.
, vol.21
, pp. 1979-1987
-
-
An, S.W.1
Cha, S.K.2
Yoon, J.3
Chang, S.4
Ross, E.M.5
Huang, C.L.6
-
2
-
-
78650926798
-
Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
-
Atwood, B. K., Lopez, J., Wager-Miller, J., Mackie, K. and Straiker, A. (2011). Expression of G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. BMC Genomics 12, 14.
-
(2011)
BMC Genomics
, vol.12
, pp. 14
-
-
Atwood, B.K.1
Lopez, J.2
Wager-Miller, J.3
Mackie, K.4
Straiker, A.5
-
3
-
-
79959764729
-
Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1
-
Ben Sahra, I., Regazzetti, C., Robert, G., Laurent, K., Le Marchand-Brustel, Y., Auberger, P., Tanti, J. F., Giorgetti-Peraldi, S. and Bost, F. (2011). Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. Cancer Res. 71, 4366-4372.
-
(2011)
Cancer Res.
, vol.71
, pp. 4366-4372
-
-
Ben Sahra, I.1
Regazzetti, C.2
Robert, G.3
Laurent, K.4
Le Marchand-Brustel, Y.5
Auberger, P.6
Tanti, J.F.7
Giorgetti-Peraldi, S.8
Bost, F.9
-
4
-
-
73249130775
-
L-type Ca(2+) current in ventricular cardiomyocytes
-
Benitah, J. P., Alvarez, J. L. and Gómez, A. M. (2010). L-type Ca(2+) current in ventricular cardiomyocytes. J. Mol. Cell Cardiol. 48, 26-36.
-
(2010)
J. Mol. Cell Cardiol.
, vol.48
, pp. 26-36
-
-
Benitah, J.P.1
Alvarez, J.L.2
Gómez, A.M.3
-
5
-
-
10044276783
-
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
-
Brugarolas, J., Lei, K., Hurley, R. L., Manning, B. D., Reiling, J. H., Hafen, E., Witters, L. A., Ellisen, L. W. and Kaelin, W. G., Jr (2004). Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev. 18, 2893-2904.
-
(2004)
Genes Dev.
, vol.18
, pp. 2893-2904
-
-
Brugarolas, J.1
Lei, K.2
Hurley, R.L.3
Manning, B.D.4
Reiling, J.H.5
Hafen, E.6
Witters, L.A.7
Ellisen, L.W.8
Kaelin, W.G.9
-
6
-
-
77954129578
-
Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids
-
Bryksin, A. V. and Matsumura, I. (2010). Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids. Biotechniques 48, 463-465.
-
(2010)
Biotechniques
, vol.48
, pp. 463-465
-
-
Bryksin, A.V.1
Matsumura, I.2
-
7
-
-
77951230331
-
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling
-
Busillo, J. M., Armando, S., Sengupta, R., Meucci, O., Bouvier, M. and Benovic, J. L. (2010). Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J. Biol. Chem. 285, 7805-7817.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7805-7817
-
-
Busillo, J.M.1
Armando, S.2
Sengupta, R.3
Meucci, O.4
Bouvier, M.5
Benovic, J.L.6
-
8
-
-
7244250134
-
Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance
-
Cézanne, L., Lecat, S., Lagane, B., Millot, C., Vollmer, J. Y., Matthes, H., Galzi, J. L. and Lopez, A. (2004). Dynamic confinement of NK2 receptors in the plasma membrane. Improved FRAP analysis and biological relevance. J. Biol. Chem. 279, 45057-45067.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45057-45067
-
-
Cézanne, L.1
Lecat, S.2
Lagane, B.3
Millot, C.4
Vollmer, J.Y.5
Matthes, H.6
Galzi, J.L.7
Lopez, A.8
-
9
-
-
15444362044
-
The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway
-
Corradetti, M. N., Inoki, K. and Guan, K. L. (2005). The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J. Biol. Chem. 280, 9769-9772.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 9769-9772
-
-
Corradetti, M.N.1
Inoki, K.2
Guan, K.L.3
-
10
-
-
59549102113
-
Recent methodological advances in the discovery of GPCR-associated protein complexes
-
Daulat, A. M., Maurice, P. and Jockers, R. (2009). Recent methodological advances in the discovery of GPCR-associated protein complexes. Trends Pharmacol. Sci. 30, 72-78.
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 72-78
-
-
Daulat, A.M.1
Maurice, P.2
Jockers, R.3
-
11
-
-
37249032471
-
Fast 4D Microscopy
-
De Mey, J. R., Kessler, P., Dompierre, J., Cordelières, F. P., Dieterlen, A., Vonesch, J. L. and Sibarita, J. B. (2008). Fast 4D Microscopy. Methods Cell Biol. 85, 83-112.
-
(2008)
Methods Cell Biol.
, vol.85
, pp. 83-112
-
-
De Mey, J.R.1
Kessler, P.2
Dompierre, J.3
Cordelières, F.P.4
Dieterlen, A.5
Vonesch, J.L.6
Sibarita, J.B.7
-
12
-
-
78149422176
-
Identification and functional analysis of endothelial tip cell-enriched genes
-
del Toro, R., Prahst, C., Mathivet, T., Siegfried, G., Kaminker, J. S., Larrivee, B., Breant, C., Duarte, A., Takakura, N., Fukamizu, A. et al. (2010). Identification and functional analysis of endothelial tip cell-enriched genes. Blood 116, 4025-4033.
-
(2010)
Blood
, vol.116
, pp. 4025-4033
-
-
del Toro, R.1
Prahst, C.2
Mathivet, T.3
Siegfried, G.4
Kaminker, J.S.5
Larrivee, B.6
Breant, C.7
Duarte, A.8
Takakura, N.9
Fukamizu, A.10
-
13
-
-
38349056675
-
Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
-
DeYoung, M. P., Horak, P., Sofer, A., Sgroi, D. and Ellisen, L. W. (2008). Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling. Genes Dev. 22, 239-251.
-
(2008)
Genes Dev.
, vol.22
, pp. 239-251
-
-
DeYoung, M.P.1
Horak, P.2
Sofer, A.3
Sgroi, D.4
Ellisen, L.W.5
-
14
-
-
41949089470
-
beta-arrestin-biased agonism at the beta2-adrenergic receptor
-
Drake, M. T., Violin, J. D., Whalen, E. J., Wisler, J. W., Shenoy, S. K. and Lefkowitz, R. J. (2008). beta-arrestin-biased agonism at the beta2-adrenergic receptor. J. Biol. Chem. 283, 5669-5676.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5669-5676
-
-
Drake, M.T.1
Violin, J.D.2
Whalen, E.J.3
Wisler, J.W.4
Shenoy, S.K.5
Lefkowitz, R.J.6
-
15
-
-
0028303137
-
Cell signalling and the control of gene transcription
-
Edwards, D. R. (1994). Cell signalling and the control of gene transcription. Trends Pharmacol. Sci. 15, 239-244.
-
(1994)
Trends Pharmacol. Sci.
, vol.15
, pp. 239-244
-
-
Edwards, D.R.1
-
16
-
-
39049185811
-
Growth control under stress: mTOR regulation through the REDD1-TSC pathway
-
Ellisen, L. W. (2005). Growth control under stress: mTOR regulation through the REDD1-TSC pathway. Cell Cycle 4, 1500-1502.
-
(2005)
Cell Cycle
, vol.4
, pp. 1500-1502
-
-
Ellisen, L.W.1
-
17
-
-
0036863624
-
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
-
Ellisen, L. W., Ramsayer, K. D., Johannessen, C. M., Yang, A., Beppu, H., Minda, K., Oliner, J. D., McKeon, F. and Haber, D. A. (2002). REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol. Cell 10, 995-1005.
-
(2002)
Mol. Cell
, vol.10
, pp. 995-1005
-
-
Ellisen, L.W.1
Ramsayer, K.D.2
Johannessen, C.M.3
Yang, A.4
Beppu, H.5
Minda, K.6
Oliner, J.D.7
McKeon, F.8
Haber, D.A.9
-
18
-
-
84871542504
-
The stressresponse gene redd1 regulates dorsoventral patterning by antagonizing Wnt/bcatenin activity in zebrafish
-
Feng, Q., Zou, X., Lu, L., Li, Y., Liu, Y., Zhou, J. and Duan, C. (2012). The stressresponse gene redd1 regulates dorsoventral patterning by antagonizing Wnt/bcatenin activity in zebrafish. PLoS ONE 7, e52674.
-
(2012)
PLoS ONE
, vol.7
-
-
Feng, Q.1
Zou, X.2
Lu, L.3
Li, Y.4
Liu, Y.5
Zhou, J.6
Duan, C.7
-
19
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke, T. F., Kaplan, D. R., Cantley, L. C. and Toker, A. (1997). Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275, 665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
20
-
-
0036841033
-
Beta(2)-adrenergic receptor lacking the cyclic AMP-dependent protein kinase consensus sites fully activates extracellular signal-regulated kinase 1/2 in human embryonic kidney 293 cells: lack of evidence for G(s)/G(i) switching
-
Friedman, J., Babu, B. and Clark, R. B. (2002). Beta(2)-adrenergic receptor lacking the cyclic AMP-dependent protein kinase consensus sites fully activates extracellular signal-regulated kinase 1/2 in human embryonic kidney 293 cells: lack of evidence for G(s)/G(i) switching. Mol. Pharmacol. 62, 1094-1102.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1094-1102
-
-
Friedman, J.1
Babu, B.2
Clark, R.B.3
-
21
-
-
72449201711
-
Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes
-
Frost, R. A., Huber, D., Pruznak, A. and Lang, C. H. (2009). Regulation of REDD1 by insulin-like growth factor-I in skeletal muscle and myotubes. J. Cell. Biochem. 108, 1192-1202.
-
(2009)
J. Cell. Biochem.
, vol.108
, pp. 1192-1202
-
-
Frost, R.A.1
Huber, D.2
Pruznak, A.3
Lang, C.H.4
-
22
-
-
34447642715
-
The evasive nature of drug efficacy: implications for drug discovery
-
Galandrin, S., Oligny-Longpré, G. and Bouvier, M. (2007). The evasive nature of drug efficacy: implications for drug discovery. Trends Pharmacol. Sci. 28, 423-430.
-
(2007)
Trends Pharmacol. Sci.
, vol.28
, pp. 423-430
-
-
Galandrin, S.1
Oligny-Longpré, G.2
Bouvier, M.3
-
23
-
-
0033604903
-
A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells.cross-talk between cyclic AMP and protein kinase c pathways
-
Gao, Z., Chen, T., Weber, M. J. and Linden, J. (1999). A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. cross-talk between cyclic AMP and protein kinase c pathways. J. Biol. Chem. 274, 5972-5980.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5972-5980
-
-
Gao, Z.1
Chen, T.2
Weber, M.J.3
Linden, J.4
-
24
-
-
0037155272
-
Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor
-
Gicquiaux, H., Lecat, S., Gaire, M., Dieterlen, A., Mély, Y., Takeda, K., Bucher, B. and Galzi, J. L. (2002). Rapid internalization and recycling of the human neuropeptide Y Y(1) receptor. J. Biol. Chem. 277, 6645-6655.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6645-6655
-
-
Gicquiaux, H.1
Lecat, S.2
Gaire, M.3
Dieterlen, A.4
Mély, Y.5
Takeda, K.6
Bucher, B.7
Galzi, J.L.8
-
25
-
-
33845359060
-
FRETand colocalization analyzer-a method to validate measurements of sensitized emission FRET acquired by confocal microscopy and available as an ImageJ Plug-in
-
Hachet-Haas, M., Converset, N., Marchal, O., Matthes, H., Gioria, S., Galzi, J. L. and Lecat, S. (2006). FRETand colocalization analyzer-a method to validate measurements of sensitized emission FRET acquired by confocal microscopy and available as an ImageJ Plug-in. Microsc. Res. Tech. 69, 941-956.
-
(2006)
Microsc. Res. Tech.
, vol.69
, pp. 941-956
-
-
Hachet-Haas, M.1
Converset, N.2
Marchal, O.3
Matthes, H.4
Gioria, S.5
Galzi, J.L.6
Lecat, S.7
-
26
-
-
53149089094
-
Small neutralizing molecules to inhibit actions of the chemokine CXCL12
-
Hachet-Haas, M.,Balabanian, K.,Rohmer, F., Pons, F., Franchet,C., Lecat, S., Chow, K. Y., Dagher, R., Gizzi, P., Didier, B. et al. (2008). Small neutralizing molecules to inhibit actions of the chemokine CXCL12. J. Biol. Chem. 283, 23189-23199.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 23189-23199
-
-
Hachet-Haas, M.1
Balabanian, K.2
Rohmer, F.3
Pons, F.4
Franchet, C.5
Lecat, S.6
Chow, K.Y.7
Dagher, R.8
Gizzi, P.9
Didier, B.10
-
27
-
-
33745143631
-
Galpha12/13-and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors
-
Hains, M. D., Wing, M. R., Maddileti, S., Siderovski, D. P. and Harden, T. K. (2006). Galpha12/13-and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors. Mol. Pharmacol. 69, 2068-2075.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 2068-2075
-
-
Hains, M.D.1
Wing, M.R.2
Maddileti, S.3
Siderovski, D.P.4
Harden, T.K.5
-
28
-
-
0030712369
-
Regulation of human chemokine receptors CXCR4.Role of phosphorylation in desensitization and internalization
-
Haribabu, B., Richardson, R. M., Fisher, I., Sozzani, S., Peiper, S. C., Horuk, R., Ali, H. and Snyderman, R. (1997). Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization. J. Biol. Chem. 272, 28726-28731.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 28726-28731
-
-
Haribabu, B.1
Richardson, R.M.2
Fisher, I.3
Sozzani, S.4
Peiper, S.C.5
Horuk, R.6
Ali, H.7
Snyderman, R.8
-
29
-
-
33845313646
-
PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane
-
Heo, W. D., Inoue, T., Park, W. S., Kim, M. L., Park, B. O., Wandless, T. J. and Meyer, T. (2006). PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science 314, 1458-1461.
-
(2006)
Science
, vol.314
, pp. 1458-1461
-
-
Heo, W.D.1
Inoue, T.2
Park, W.S.3
Kim, M.L.4
Park, B.O.5
Wandless, T.J.6
Meyer, T.7
-
30
-
-
0038540318
-
Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors
-
Hermans, E. (2003). Biochemical and pharmacological control of the multiplicity of coupling at G-protein-coupled receptors. Pharmacol. Ther. 99, 25-44.
-
(2003)
Pharmacol. Ther.
, vol.99
, pp. 25-44
-
-
Hermans, E.1
-
31
-
-
77949535410
-
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
-
Horak, P., Crawford, A. R., Vadysirisack, D. D., Nash, Z. M., DeYoung, M. P., Sgroi, D. and Ellisen, L. W. (2010). Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis. Proc. Natl. Acad. Sci. USA 107, 4675-4680.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4675-4680
-
-
Horak, P.1
Crawford, A.R.2
Vadysirisack, D.D.3
Nash, Z.M.4
DeYoung, M.P.5
Sgroi, D.6
Ellisen, L.W.7
-
32
-
-
33750837563
-
Highcontent screening of known G protein-coupled receptors by arrestin translocation
-
Hudson, C. C., Oakley, R. H., Sjaastad, M. D. and Loomis, C. R. (2006). Highcontent screening of known G protein-coupled receptors by arrestin translocation. Methods Enzymol. 414, 63-78.
-
(2006)
Methods Enzymol.
, vol.414
, pp. 63-78
-
-
Hudson, C.C.1
Oakley, R.H.2
Sjaastad, M.D.3
Loomis, C.R.4
-
33
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki, K., Li, Y., Zhu, T., Wu, J. andGuan, K. L. (2002). TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat. Cell Biol. 4, 648-657.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
34
-
-
0029885318
-
Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors
-
Jiang, H., Kuang, Y., Wu, Y., Smrcka, A., Simon, M. I. and Wu, D. (1996). Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors. J. Biol. Chem. 271, 13430-13434.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13430-13434
-
-
Jiang, H.1
Kuang, Y.2
Wu, Y.3
Smrcka, A.4
Simon, M.I.5
Wu, D.6
-
35
-
-
68249104457
-
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase
-
Katiyar, S., Liu, E., Knutzen, C. A., Lang, E. S., Lombardo, C. R., Sankar, S., Toth, J. I., Petroski, M. D., Ronai, Z. and Chiang, G. G. (2009). REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase. EMBO Rep. 10, 866-872.
-
(2009)
EMBO Rep.
, vol.10
, pp. 866-872
-
-
Katiyar, S.1
Liu, E.2
Knutzen, C.A.3
Lang, E.S.4
Lombardo, C.R.5
Sankar, S.6
Toth, J.I.7
Petroski, M.D.8
Ronai, Z.9
Chiang, G.G.10
-
36
-
-
41249094257
-
Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis
-
Kimball, S. R., Do, A. N., Kutzler, L., Cavener, D. R. and Jefferson, L. S. (2008). Rapid turnover of the mTOR complex 1 (mTORC1) repressor REDD1 and activation of mTORC1 signaling following inhibition of protein synthesis. J. Biol. Chem. 283, 3465-3475.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3465-3475
-
-
Kimball, S.R.1
Do, A.N.2
Kutzler, L.3
Cavener, D.R.4
Jefferson, L.S.5
-
37
-
-
77957767363
-
Contribution of a tyrosinebased motif to cellular trafficking of wild-type and truncated NPY Y(1) receptors
-
Lecat, S., Ouédraogo, M., Cherrier, T., Noulet, F., Rondé , P., Glasser, N., Galzi, J. L., Mely, Y., Takeda, K. and Bucher, B. (2011). Contribution of a tyrosinebased motif to cellular trafficking of wild-type and truncated NPY Y(1) receptors. Cell. Signal. 23, 228-238.
-
(2011)
Cell. Signal.
, vol.23
, pp. 228-238
-
-
Lecat, S.1
Ouédraogo, M.2
Cherrier, T.3
Noulet, F.4
Rondé, P.5
Glasser, N.6
Galzi, J.L.7
Mely, Y.8
Takeda, K.9
Bucher, B.10
-
38
-
-
28044463802
-
Arsenite induces a cell stressresponse gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein
-
Lin, L., Stringfield, T. M., Shi, X. and Chen, Y. (2005). Arsenite induces a cell stressresponse gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein. Biochem. J. 392, 93-102.
-
(2005)
Biochem. J.
, vol.392
, pp. 93-102
-
-
Lin, L.1
Stringfield, T.M.2
Shi, X.3
Chen, Y.4
-
39
-
-
0032836645
-
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells
-
Linden, J., Thai, T., Figler, H., Jin, X. and Robeva, A. S. (1999). Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Mol. Pharmacol. 56, 705-713.
-
(1999)
Mol. Pharmacol.
, vol.56
, pp. 705-713
-
-
Linden, J.1
Thai, T.2
Figler, H.3
Jin, X.4
Robeva, A.S.5
-
40
-
-
33748101201
-
Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output
-
Loening, A. M., Fenn, T. D., Wu, A. M. and Gambhir, S. S. (2006). Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output. Protein Eng. Des. Sel. 19, 391-400.
-
(2006)
Protein Eng. Des. Sel.
, vol.19
, pp. 391-400
-
-
Loening, A.M.1
Fenn, T.D.2
Wu, A.M.3
Gambhir, S.S.4
-
41
-
-
79952263151
-
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration
-
Malagelada, C., Ló pez-Toledano, M. A., Willett, R. T., Jin, Z. H., Shelanski, M. L. and Greene, L. A. (2011). RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. J. Neurosci. 31, 3186-3196.
-
(2011)
J. Neurosci.
, vol.31
, pp. 3186-3196
-
-
Malagelada, C.1
Ló pez-Toledano, M.A.2
Willett, R.T.3
Jin, Z.H.4
Shelanski, M.L.5
Greene, L.A.6
-
42
-
-
80052964913
-
Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor
-
Mata, M. A., Satterly, N., Versteeg, G. A., Frantz, D., Wei, S., Williams, N., Schmolke, M., Peña-Llopis, S., Brugarolas, J., Forst, C. V. et al. (2011). Chemical inhibition of RNA viruses reveals REDD1 as a host defense factor. Nat. Chem. Biol. 7, 712-719.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 712-719
-
-
Mata, M.A.1
Satterly, N.2
Versteeg, G.A.3
Frantz, D.4
Wei, S.5
Williams, N.6
Schmolke, M.7
Peña-Llopis, S.8
Brugarolas, J.9
Forst, C.V.10
-
43
-
-
84867068453
-
5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia
-
Meffre, J., Chaumont-Dubel, S., Mannoury la Cour, C., Loiseau, F., Watson, D. J., Dekeyne, A., Séveno, M., Rivet, J. M., Gaven, F., Déléris, P. et al. (2012). 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia. EMBO Mol. Med. 4, 1043-1056.
-
(2012)
EMBO Mol. Med.
, vol.4
, pp. 1043-1056
-
-
Meffre, J.1
Chaumont-Dubel, S.2
Mannoury la Cour, C.3
Loiseau, F.4
Watson, D.J.5
Dekeyne, A.6
Séveno, M.7
Rivet, J.M.8
Gaven, F.9
Déléris, P.10
-
44
-
-
65249157359
-
REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch
-
Miyazaki, M. and Esser, K. A. (2009). REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch. Am. J. Physiol. 296, C583-C592.
-
(2009)
Am. J. Physiol.
, vol.296
-
-
Miyazaki, M.1
Esser, K.A.2
-
45
-
-
79960018488
-
ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Ga(q/11)
-
Montmayeur, J. P., Barr, T. P., Kam, S. A., Packer, S. J. and Strichartz, G. R. (2011). ET-1 induced Elevation of intracellular calcium in clonal neuronal and embryonic kidney cells involves endogenous endothelin-A receptors linked to phospholipase C through Ga(q/11). Pharmacol. Res. 64, 258-267.
-
(2011)
Pharmacol. Res.
, vol.64
, pp. 258-267
-
-
Montmayeur, J.P.1
Barr, T.P.2
Kam, S.A.3
Packer, S.J.4
Strichartz, G.R.5
-
46
-
-
58149488988
-
The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development
-
Morrison, D. K. (2009). The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol. 19, 16-23.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 16-23
-
-
Morrison, D.K.1
-
47
-
-
77951891355
-
GPCR signalling to the translation machinery
-
Musnier, A., Blanchot, B., Reiter, E. and Crépieux, P. (2010). GPCR signalling to the translation machinery. Cell. Signal. 22, 707-716.
-
(2010)
Cell. Signal.
, vol.22
, pp. 707-716
-
-
Musnier, A.1
Blanchot, B.2
Reiter, E.3
Crépieux, P.4
-
48
-
-
84884175477
-
DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination
-
Noseda, R., Belin, S., Piguet, F., Vaccari, I., Scarlino, S., Brambilla, P., Martinelli Boneschi, F., Feltri, M. L., Wrabetz, L., Quattrini, A. et al. (2013). DDIT4/REDD1/RTP801 is a novel negative regulator of Schwann cell myelination. J. Neurosci. 33, 15295-15305.
-
(2013)
J. Neurosci.
, vol.33
, pp. 15295-15305
-
-
Noseda, R.1
Belin, S.2
Piguet, F.3
Vaccari, I.4
Scarlino, S.5
Brambilla, P.6
Martinelli Boneschi, F.7
Feltri, M.L.8
Wrabetz, L.9
Quattrini, A.10
-
49
-
-
38849196399
-
Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization
-
Ouedraogo, M., Lecat, S., Rochdi, M. D., Hachet-Haas, M., Matthes, H., Gicquiaux, H., Verrier, S., Gaire, M., Glasser, N., Mély, Y. et al. (2008). Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization. Traffic 9, 305-324.
-
(2008)
Traffic
, vol.9
, pp. 305-324
-
-
Ouedraogo, M.1
Lecat, S.2
Rochdi, M.D.3
Hachet-Haas, M.4
Matthes, H.5
Gicquiaux, H.6
Verrier, S.7
Gaire, M.8
Glasser, N.9
Mély, Y.10
-
50
-
-
77949315518
-
Insulin induces REDD1 expression through hypoxiainducible factor 1 activation in adipocytes
-
Regazzetti, C., Bost, F., Le Marchand-Brustel, Y., Tanti, J. F. and Giorgetti-Peraldi, S. (2010). Insulin induces REDD1 expression through hypoxiainducible factor 1 activation in adipocytes. J. Biol. Chem. 285, 5157-5164.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5157-5164
-
-
Regazzetti, C.1
Bost, F.2
Le Marchand-Brustel, Y.3
Tanti, J.F.4
Giorgetti-Peraldi, S.5
-
51
-
-
84871313202
-
Regulated in development and DNA damage responses 21 (REDD1) protein contributes to insulin signaling pathway in adipocytes
-
Regazzetti, C., Dumas, K., Le Marchand-Brustel, Y., Peraldi, P., Tanti, J. F. and Giorgetti-Peraldi, S. (2012). Regulated in development and DNA damage responses 21 (REDD1) protein contributes to insulin signaling pathway in adipocytes. PLoS ONE 7, e52154.
-
(2012)
PLoS ONE
, vol.7
-
-
Regazzetti, C.1
Dumas, K.2
Le Marchand-Brustel, Y.3
Peraldi, P.4
Tanti, J.F.5
Giorgetti-Peraldi, S.6
-
52
-
-
10044276784
-
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
-
Reiling, J. H. and Hafen, E. (2004). The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev. 18, 2879-2892.
-
(2004)
Genes Dev.
, vol.18
, pp. 2879-2892
-
-
Reiling, J.H.1
Hafen, E.2
-
53
-
-
34347242470
-
RAS/ERK signaling promotes sitespecific ribosomal protein S6 phosphorylation via RSK and stimulates capdependent translation
-
Roux, P. P., Shahbazian, D., Vu, H., Holz, M. K., Cohen, M. S., Taunton, J., Sonenberg, N. and Blenis, J. (2007). RAS/ERK signaling promotes sitespecific ribosomal protein S6 phosphorylation via RSK and stimulates capdependent translation. J. Biol. Chem. 282, 14056-14064.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14056-14064
-
-
Roux, P.P.1
Shahbazian, D.2
Vu, H.3
Holz, M.K.4
Cohen, M.S.5
Taunton, J.6
Sonenberg, N.7
Blenis, J.8
-
54
-
-
35848943698
-
Mitogenic signaling pathways induced by G proteincoupled receptors
-
Rozengurt, E. (2007). Mitogenic signaling pathways induced by G proteincoupled receptors. J. Cell. Physiol. 213, 589-602.
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 589-602
-
-
Rozengurt, E.1
-
55
-
-
77951708711
-
Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer
-
Rozengurt, E., Sinnett-Smith, J. and Kisfalvi, K. (2010). Crosstalk between insulin/insulin-like growth factor-1 receptors and G protein-coupled receptor signaling systems: a novel target for the antidiabetic drug metformin in pancreatic cancer. Clin. Cancer Res. 16, 2505-2511.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2505-2511
-
-
Rozengurt, E.1
Sinnett-Smith, J.2
Kisfalvi, K.3
-
56
-
-
0035947758
-
Nucleolar assembly of the rRNA processing machinery in living cells
-
Savino, T. M., Gébrane-Younès, J., De Mey, J., Sibarita, J. B. and Hernandez-Verdun, D. (2001). Nucleolar assembly of the rRNA processing machinery in living cells. J. Cell Biol. 153, 1097-1110.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1097-1110
-
-
Savino, T.M.1
Gébrane-Younès, J.2
De Mey, J.3
Sibarita, J.B.4
Hernandez-Verdun, D.5
-
57
-
-
14644395545
-
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase
-
Schwarzer, R., Tondera, D., Arnold, W., Giese, K., Klippel, A. and Kaufmann, J. (2005). REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene 24, 1138-1149.
-
(2005)
Oncogene
, vol.24
, pp. 1138-1149
-
-
Schwarzer, R.1
Tondera, D.2
Arnold, W.3
Giese, K.4
Klippel, A.5
Kaufmann, J.6
-
58
-
-
33644779527
-
scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila
-
Scuderi, A., Simin, K., Kazuko, S. G., Metherall, J. E. and Letsou, A. (2006). scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila. Dev. Biol. 291, 110-122.
-
(2006)
Dev. Biol.
, vol.291
, pp. 110-122
-
-
Scuderi, A.1
Simin, K.2
Kazuko, S.G.3
Metherall, J.E.4
Letsou, A.5
-
59
-
-
0036618178
-
Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
-
Shaw, G., Morse, S., Ararat, M. and Graham, F. L. (2002). Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 16, 869-871.
-
(2002)
FASEB J.
, vol.16
, pp. 869-871
-
-
Shaw, G.1
Morse, S.2
Ararat, M.3
Graham, F.L.4
-
60
-
-
33644857279
-
betaarrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor
-
Shenoy, S. K., Drake, M. T., Nelson, C. D., Houtz, D. A., Xiao, K., Madabushi, S., Reiter, E., Premont, R. T., Lichtarge, O. and Lefkowitz, R. J. (2006). betaarrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J. Biol. Chem. 281, 1261-1273.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 1261-1273
-
-
Shenoy, S.K.1
Drake, M.T.2
Nelson, C.D.3
Houtz, D.A.4
Xiao, K.5
Madabushi, S.6
Reiter, E.7
Premont, R.T.8
Lichtarge, O.9
Lefkowitz, R.J.10
-
61
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis
-
Shoshani, T., Faerman, A., Mett, I., Zelin, E., Tenne, T., Gorodin, S., Moshel, Y., Elbaz, S. M., Budanov, A., Chajut, A. et al. (2002). Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol. Cell Biol. 7, 2283-2293.
-
(2002)
Mol. Cell Biol.
, vol.7
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.M.8
Budanov, A.9
Chajut, A.10
-
62
-
-
0034280113
-
Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing
-
Simpson, J. C., Wellenreuther, R., Poustka, A., Pepperkok, R. and Wiemann, S. (2000). Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Rep. 1, 287-292.
-
(2000)
EMBO Rep.
, vol.1
, pp. 287-292
-
-
Simpson, J.C.1
Wellenreuther, R.2
Poustka, A.3
Pepperkok, R.4
Wiemann, S.5
-
63
-
-
21744459535
-
Regulation ofmTOR and cell growth in response to energy stress by REDD1
-
Sofer, A., Lei, K., Johannessen, C.M. and Ellisen, L.W. (2005). Regulation ofmTOR and cell growth in response to energy stress by REDD1. Mol. Cell. Biol. 25, 5834-5845.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5834-5845
-
-
Sofer, A.1
Lei, K.2
Johannessen, C.M.3
Ellisen, L.W.4
-
64
-
-
84855398689
-
Impedance responses reveal b2-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles
-
Stallaert, W., Dorn, J. F., van der Westhuizen, E., Audet, M. and Bouvier, M. (2012). Impedance responses reveal b2-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles. PLoS ONE 7, e29420.
-
(2012)
PLoS ONE
, vol.7
-
-
Stallaert, W.1
Dorn, J.F.2
van der Westhuizen, E.3
Audet, M.4
Bouvier, M.5
-
65
-
-
0034644538
-
Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction
-
Teruel, M. N. and Meyer, T. (2000). Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction. Cell 103, 181-184.
-
(2000)
Cell
, vol.103
, pp. 181-184
-
-
Teruel, M.N.1
Meyer, T.2
-
66
-
-
84860742593
-
Organ size control by Hippo and TOR pathways
-
Tumaneng, K., Russell, R. C. and Guan, K. L. (2012). Organ size control by Hippo and TOR pathways. Curr. Biol. 22, R368-R379.
-
(2012)
Curr. Biol.
, vol.22
-
-
Tumaneng, K.1
Russell, R.C.2
Guan, K.L.3
-
67
-
-
84873448916
-
Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway
-
Varghese, B. V., Koohestani, F., McWilliams, M., Colvin, A., Gunewardena, S., Kinsey, W. H., Nowak, R. A., Nothnick, W. B. and Chennathukuzhi, V. M. (2013). Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway. Proc. Natl. Acad. Sci. USA 110, 2187-2192.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 2187-2192
-
-
Varghese, B.V.1
Koohestani, F.2
McWilliams, M.3
Colvin, A.4
Gunewardena, S.5
Kinsey, W.H.6
Nowak, R.A.7
Nothnick, W.B.8
Chennathukuzhi, V.M.9
-
68
-
-
77949528224
-
Structural analysis and functional implications of the negative mTORC1 regulator REDD1
-
Vega-Rubin-de-Celis, S., Abdallah, Z., Kinch, L., Grishin, N. V., Brugarolas, J. and Zhang, X. (2010). Structural analysis and functional implications of the negative mTORC1 regulator REDD1. Biochemistry 49, 2491-2501.
-
(2010)
Biochemistry
, vol.49
, pp. 2491-2501
-
-
Vega-Rubin-de-Celis, S.1
Abdallah, Z.2
Kinch, L.3
Grishin, N.V.4
Brugarolas, J.5
Zhang, X.6
-
69
-
-
0033621359
-
Subcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors
-
Vollmer, J. Y., Alix, P., Chollet, A., Takeda, K. and Galzi, J. L. (1999). Subcellular compartmentalization of activation and desensitization of responses mediated by NK2 neurokinin receptors. J. Biol. Chem. 274, 37915-37922.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37915-37922
-
-
Vollmer, J.Y.1
Alix, P.2
Chollet, A.3
Takeda, K.4
Galzi, J.L.5
-
70
-
-
84866846953
-
The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy
-
Wauson, E. M., Zaganjor, E., Lee, A. Y., Guerra, M. L., Ghosh, A. B., Bookout, A. L., Chambers, C. P., Jivan, A., McGlynn, K., Hutchison, M. R. et al. (2012). The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy. Mol. Cell 47, 851-862.
-
(2012)
Mol. Cell
, vol.47
, pp. 851-862
-
-
Wauson, E.M.1
Zaganjor, E.2
Lee, A.Y.3
Guerra, M.L.4
Ghosh, A.B.5
Bookout, A.L.6
Chambers, C.P.7
Jivan, A.8
McGlynn, K.9
Hutchison, M.R.10
-
71
-
-
84865260845
-
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
-
Yu, F. X., Zhao, B., Panupinthu, N., Jewell, J. L., Lian, I., Wang, L. H., Zhao, J., Yuan, H., Tumaneng, K., Li, H. et al. (2012). Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150, 780-791.
-
(2012)
Cell
, vol.150
, pp. 780-791
-
-
Yu, F.X.1
Zhao, B.2
Panupinthu, N.3
Jewell, J.L.4
Lian, I.5
Wang, L.H.6
Zhao, J.7
Yuan, H.8
Tumaneng, K.9
Li, H.10
-
72
-
-
0037012847
-
Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells
-
Zacharias, D. A., Violin, J. D., Newton, A. C. and Tsien, R. Y. (2002). Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science 296, 913-916.
-
(2002)
Science
, vol.296
, pp. 913-916
-
-
Zacharias, D.A.1
Violin, J.D.2
Newton, A.C.3
Tsien, R.Y.4
|