-
1
-
-
17644367544
-
Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes
-
DOI 10.1523/JNEUROSCI.3447-04.2005
-
Angelastro JM, Mason JL, Ignatova TN, Kukekov VG, Stengren GB, Goldman JE, Greene LA (2005) Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes. J Neurosci 25:3889-3899. (Pubitemid 40570422)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.15
, pp. 3889-3899
-
-
Angelastro, J.M.1
Mason, J.L.2
Ignatova, T.N.3
Kukekov, V.G.4
Stengren, G.B.5
Goldman, J.E.6
Greene, L.A.7
-
2
-
-
67650074206
-
mTOR regulates memory CD8 T-cell differentiation
-
Araki K, Turner AP, Shaffer VO, Gangappa S, Keller SA, Bachmann MF, Larsen CP, Ahmed R (2009) mTOR regulates memory CD8 T-cell differentiation. Nature 460:108-112.
-
(2009)
Nature
, vol.460
, pp. 108-112
-
-
Araki, K.1
Turner, A.P.2
Shaffer, V.O.3
Gangappa, S.4
Keller, S.A.5
Bachmann, M.F.6
Larsen, C.P.7
Ahmed, R.8
-
3
-
-
5344224052
-
Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila
-
DOI 10.1016/j.cell.2004.08.028, PII S0092867404008037
-
Bateman JM, McNeill H (2004) Temporal control of differentiation by the insulin receptor/tor pathway in Drosophila. Cell 119:87-96. (Pubitemid 39349322)
-
(2004)
Cell
, vol.119
, Issue.1
, pp. 87-96
-
-
Bateman, J.M.1
McNeill, H.2
-
4
-
-
33747121607
-
Insulin/IGF signalling in neurogenesis
-
DOI 10.1007/s00018-006-6036-4
-
Bateman JM, McNeill H (2006) Insulin/IGF signalling in neurogenesis. Cell Mol Life Sci 63:1701-1705. (Pubitemid 44223080)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.15
, pp. 1701-1705
-
-
Bateman, J.M.1
McNeill, H.2
-
5
-
-
10044276783
-
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
-
DOI 10.1101/gad.1256804
-
Brugarolas J, Lei K, Hurley RL, Manning BD, Reiling JH, Hafen E, Witters LA, Ellisen LW, Kaelin WG Jr (2004) Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev 18:2893-2904. (Pubitemid 39602308)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2893-2904
-
-
Brugarolas, J.1
Lei, K.2
Hurley, R.L.3
Manning, B.D.4
Reiling, J.H.5
Hafen, E.6
Witters, L.A.7
Ellisen, L.W.8
Kaelin Jr., W.G.9
-
7
-
-
58749109756
-
Regulation of mTOR and p70 S6 kinase by the muscarinic M4 receptor in PC12 cells
-
Chan GP, Wu EH, Wong YH (2009) Regulation of mTOR and p70 S6 kinase by the muscarinic M4 receptor in PC12 cells. Cell Biol Int 33:230-238.
-
(2009)
Cell Biol Int
, vol.33
, pp. 230-238
-
-
Chan, G.P.1
Wu, E.H.2
Wong, Y.H.3
-
8
-
-
62449242845
-
REDD1 is required for RAS-mediated transformation of human ovarian epithelial cells
-
Chang B, Liu G, Yang G, Mercado-Uribe I, Huang M, Liu J (2009) REDD1 is required for RAS-mediated transformation of human ovarian epithelial cells. Cell Cycle 8:780-786.
-
(2009)
Cell Cycle
, vol.8
, pp. 780-786
-
-
Chang, B.1
Liu, G.2
Yang, G.3
Mercado-Uribe, I.4
Huang, M.5
Liu, J.6
-
9
-
-
15444362044
-
The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway
-
DOI 10.1074/jbc.C400557200
-
Corradetti MN, Inoki K, Guan KL (2005) The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J Biol Chem 280:9769-9772. (Pubitemid 40395821)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 9769-9772
-
-
Corradetti, M.N.1
Inoki, K.2
Guan, K.-L.3
-
10
-
-
70349221090
-
Focal brain malformations: Seizures, signaling, sequencing
-
Crino PB (2009) Focal brain malformations: seizures, signaling, sequencing. Epilepsia 50 [Suppl 9]:3-8.
-
(2009)
Epilepsia
, vol.50
, Issue.SUPPL. 9
, pp. 3-8
-
-
Crino, P.B.1
-
11
-
-
76249124148
-
The pathophysiology of tuberous sclerosis complex
-
Crino PB (2010) The pathophysiology of tuberous sclerosis complex. Epilepsia 51 [Suppl 1]:27-29.
-
(2010)
Epilepsia
, vol.51
, Issue.SUPPL. 1
, pp. 27-29
-
-
Crino, P.B.1
-
12
-
-
38349056675
-
Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
-
DeYoung MP, Horak P, Sofer A, Sgroi D, Ellisen LW (2008) Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling. Genes Dev 22:239-251.
-
(2008)
Genes Dev
, vol.22
, pp. 239-251
-
-
DeYoung, M.P.1
Horak, P.2
Sofer, A.3
Sgroi, D.4
Ellisen, L.W.5
-
13
-
-
0033604521
-
Ribosomal S6 kinase signaling and the control of translation
-
Dufner A, Thomas G (1999) Ribosomal S6 kinase signaling and the control of translation. Exp Cell Res 253:100-109.
-
(1999)
Exp Cell Res
, vol.253
, pp. 100-109
-
-
Dufner, A.1
Thomas, G.2
-
14
-
-
39049185811
-
Growth control under stress: mTOR regulation through the REDD1-TSC pathway
-
Ellisen LW (2005) Growth control under stress: mTOR regulation through the REDD1-TSC pathway. Cell Cycle 4:1500-1502.
-
(2005)
Cell Cycle
, vol.4
, pp. 1500-1502
-
-
Ellisen, L.W.1
-
15
-
-
0036863624
-
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species
-
DOI 10.1016/S1097-2765(02)00706-2
-
Ellisen LW, Ramsayer KD, Johannessen CM, Yang A, Beppu H, Minda K, Oliner JD, McKeon F, Haber DA (2002) REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species. Mol Cell 10:995-1005. (Pubitemid 35453821)
-
(2002)
Molecular Cell
, vol.10
, Issue.5
, pp. 995-1005
-
-
Ellisen, L.W.1
Ramsayer, K.D.2
Johannessen, C.M.3
Yang, A.4
Beppu, H.5
Minda, K.6
Oliner, J.D.7
McKeon, F.8
Haber, D.A.9
-
16
-
-
0028299579
-
Brain lipid-binding protein (BLBP): A novel signaling system in the developing mammalian CNS
-
DOI 10.1016/0896-6273(94)90341-7
-
Feng L, Hatten ME, Heintz N (1994) Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron 12:895-908. (Pubitemid 24126249)
-
(1994)
Neuron
, vol.12
, Issue.4
, pp. 895-908
-
-
Feng, L.1
Hatten, M.E.2
Heintz, N.3
-
17
-
-
74749106584
-
Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube
-
Fishwick KJ, Li RA, Halley P, Deng P, Storey KG (2010) Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube. Dev Biol 338:215-225.
-
(2010)
Dev Biol
, vol.338
, pp. 215-225
-
-
Fishwick, K.J.1
Li, R.A.2
Halley, P.3
Deng, P.4
Storey, K.G.5
-
18
-
-
0345704610
-
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
-
Greene LA, Tischler AS (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci 73:2424-2428.
-
(1976)
Proc Natl Acad Sci
, vol.73
, pp. 2424-2428
-
-
Greene, L.A.1
Tischler, A.S.2
-
19
-
-
49549114025
-
Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin
-
Han J, Wang B, Xiao Z, Gao Y, Zhao Y, Zhang J, Chen B, Wang X, Dai J (2008) Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. Mol Cell Neurosci 39:118-124.
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 118-124
-
-
Han, J.1
Wang, B.2
Xiao, Z.3
Gao, Y.4
Zhao, Y.5
Zhang, J.6
Chen, B.7
Wang, X.8
Dai, J.9
-
20
-
-
0035923594
-
FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse
-
DOI 10.1073/pnas.241184198
-
Hentges KE, Sirry B, Gingeras AC, Sarbassov D, Sonenberg N, Sabatini D, Peterson AS (2001) FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse. Proc Natl Acad Sci U S A 98:13796-13801. (Pubitemid 33115978)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.24
, pp. 13796-13801
-
-
Hentges, K.E.1
Sirry, B.2
Gingeras, A.-C.3
Sarbassov, D.4
Sonenberg, N.5
Sabatini, D.6
Peterson, A.S.7
-
21
-
-
77949535410
-
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
-
Horak P, Crawford AR, Vadysirisack DD, Nash ZM, DeYoung MP, Sgroi D, Ellisen LW (2010) Negative feedback control of HIF-1 through REDD1- regulated ROS suppresses tumorigenesis. Proc Natl Acad Sci U S A 107:4675-4680.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4675-4680
-
-
Horak, P.1
Crawford, A.R.2
Vadysirisack, D.D.3
Nash, Z.M.4
DeYoung, M.P.5
Sgroi, D.6
Ellisen, L.W.7
-
22
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
DOI 10.1038/ng1494
-
Inoki K, Corradetti MN, Guan KL (2005) Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 37:19-24. (Pubitemid 40070934)
-
(2005)
Nature Genetics
, vol.37
, Issue.1
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.-L.3
-
23
-
-
39749100492
-
TOR regulation of AGC kinases in yeast and mammals
-
DOI 10.1042/BJ20071518
-
Jacinto E, Lorberg A (2008) TOR regulation of AGC kinases in yeast and mammals. Biochem J 410:19-37. (Pubitemid 351300322)
-
(2008)
Biochemical Journal
, vol.410
, Issue.1
, pp. 19-37
-
-
Jacinto, E.1
Lorberg, A.2
-
24
-
-
2942530513
-
Neurogenic effect of beta-amyloid peptide in the development of neural stem cells
-
DOI 10.1523/JNEUROSCI.0974-04.2004
-
López-Toledano MA, Shelanski ML (2004) Neurogenic effect of beta-amyloid peptide in the development of neural stem cells. J Neurosci 24:5439-5444. (Pubitemid 38747685)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.23
, pp. 5439-5444
-
-
Lopez-Toledano, M.A.1
Shelanski, M.L.2
-
25
-
-
33749166640
-
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation
-
DOI 10.1523/JNEUROSCI.3292-06.2006
-
Malagelada C, Ryu EJ, Biswas SC, Jackson-Lewis V, Greene LA (2006) RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation. J Neurosci 26:9996-10005. (Pubitemid 44477161)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.39
, pp. 9996-10005
-
-
Malagelada, C.1
Ryu, E.J.2
Biswas, S.C.3
Jackson-Lewis, V.4
Greene, L.A.5
-
26
-
-
58149395816
-
RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/ activation
-
Malagelada C, Jin ZH, Greene LA (2008) RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/ activation. J Neurosci 28:14363-14371.
-
(2008)
J Neurosci
, vol.28
, pp. 14363-14371
-
-
Malagelada, C.1
Jin, Z.H.2
Greene, L.A.3
-
27
-
-
75749127850
-
Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease
-
Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA (2010) Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. J Neurosci 30:1166-1175.
-
(2010)
J Neurosci
, vol.30
, pp. 1166-1175
-
-
Malagelada, C.1
Jin, Z.H.2
Jackson-Lewis, V.3
Przedborski, S.4
Greene, L.A.5
-
28
-
-
49849095484
-
Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila
-
McNeill H, Craig GM, Bateman JM (2008) Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila. Genetics 179:843-853.
-
(2008)
Genetics
, vol.179
, pp. 843-853
-
-
McNeill, H.1
Craig, G.M.2
Bateman, J.M.3
-
29
-
-
67649419546
-
Genetic regulation of proliferation/differentiation characteristics of neural progenitor cells in the developing neocortex
-
Mitsuhashi T, Takahashi T (2009) Genetic regulation of proliferation/differentiation characteristics of neural progenitor cells in the developing neocortex. Brain Dev 31:553-557.
-
(2009)
Brain Dev
, vol.31
, pp. 553-557
-
-
Mitsuhashi, T.1
Takahashi, T.2
-
30
-
-
40849126775
-
MTOR signaling contributes to chondrocyte differentiation
-
DOI 10.1002/dvdy.21464
-
Phornphutkul C, Wu KY, Auyeung V, Chen Q, Gruppuso PA (2008) mTOR signaling contributes to chondrocyte differentiation. Dev Dyn 237:702-712. (Pubitemid 351398036)
-
(2008)
Developmental Dynamics
, vol.237
, Issue.3
, pp. 702-712
-
-
Phornphutkul, C.1
Wu, K.-Y.2
Auyeung, V.3
Chen, Q.4
Gruppuso, P.A.5
-
31
-
-
10044276784
-
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
-
DOI 10.1101/gad.322704
-
Reiling JH, Hafen E (2004) The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila. Genes Dev 18:2879-2892. (Pubitemid 39602307)
-
(2004)
Genes and Development
, vol.18
, Issue.23
, pp. 2879-2892
-
-
Reiling, J.H.1
Hafen, E.2
-
32
-
-
14644395545
-
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase
-
DOI 10.1038/sj.onc.1208236
-
Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J (2005) REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene 24:1138-1149. (Pubitemid 40313916)
-
(2005)
Oncogene
, vol.24
, Issue.7
, pp. 1138-1149
-
-
Schwarzer, R.1
Tondera, D.2
Arnold, W.3
Giese, K.4
Klippel, A.5
Kaufmann, J.6
-
33
-
-
33644779527
-
Scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila
-
DOI 10.1016/j.ydbio.2005.12.014, PII S0012160605008912
-
Scuderi A, Simin K, Kazuko SG, Metherall JE, Letsou A (2006) scylla and charybde, homologues of the human apoptotic gene RTP801, are required for head involution in Drosophila. Dev Biol 291:110-122. (Pubitemid 43343930)
-
(2006)
Developmental Biology
, vol.291
, Issue.1
, pp. 110-122
-
-
Scuderi, A.1
Simin, K.2
Kazuko, S.G.3
Metherall, J.E.4
Letsou, A.5
-
34
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis
-
DOI 10.1128/MCB.22.7.2283-2293.2002
-
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, Kalinski H, Kamer I, Rozen A, Mor O, Keshet E, Leshkowitz D, Einat P, Skaliter R, Feinstein E (2002) Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol 22:2283-2293. (Pubitemid 34224633)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.7
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
Kalinski, H.11
Kamer, I.12
Rozen, A.13
Mor, O.14
Keshet, E.15
Leshkowitz, D.16
Einat, P.17
Skaliter, R.18
Feinstein, E.19
-
35
-
-
68849100742
-
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
-
Shu L, Houghton PJ (2009) The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts. Mol Cell Biol 29:4691-4700.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 4691-4700
-
-
Shu, L.1
Houghton, P.J.2
-
36
-
-
21744459535
-
Regulation of mTOR and cell growth in response to energy stress by REDD1
-
DOI 10.1128/MCB.25.14.5834-5845.2005
-
Sofer A, Lei K, Johannessen CM, Ellisen LW (2005) Regulation of mTOR and cell growth in response to energy stress by REDD1. Mol Cell Biol 25:5834-5845. (Pubitemid 40946541)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.14
, pp. 5834-5845
-
-
Sofer, A.1
Lei, K.2
Johannessen, C.M.3
Ellisen, L.W.4
-
37
-
-
24944431844
-
LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages
-
DOI 10.1083/jcb.200505166
-
Tsai JW, Chen Y, Kriegstein AR, Vallee RB (2005) LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages. J Cell Biol 170:935-945. (Pubitemid 41306293)
-
(2005)
Journal of Cell Biology
, vol.170
, Issue.6
, pp. 935-945
-
-
Tsai, J.-W.1
Chen, Y.2
Kriegstein, A.R.3
Vallee, R.B.4
-
38
-
-
67650002531
-
Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice
-
Tuoc TC, Radyushkin K, Tonchev AB, Piñon MC, Ashery-Padan R, Molnár Z, Davidoff MS, Stoykova A (2009) Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci 29:8335-8349.
-
(2009)
J Neurosci
, vol.29
, pp. 8335-8349
-
-
Tuoc, T.C.1
Radyushkin, K.2
Tonchev, A.B.3
Piñon, M.C.4
Ashery-Padan, R.5
Molnár, Z.6
Davidoff, M.S.7
Stoykova, A.8
-
39
-
-
66049119030
-
Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation
-
Tyler WA, Gangoli N, Gokina P, Kim HA, Covey M, Levison SW, Wood TL (2009) Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation. J Neurosci 29:6367-6378.
-
(2009)
J Neurosci
, vol.29
, pp. 6367-6378
-
-
Tyler, W.A.1
Gangoli, N.2
Gokina, P.3
Kim, H.A.4
Covey, M.5
Levison, S.W.6
Wood, T.L.7
-
40
-
-
0032167535
-
Tuberous sclerosis-related gene expression in normal and dysplastic brain
-
DOI 10.1016/S0920-1211(98)00036-9, PII S0920121198000369
-
Vinters HV, Kerfoot C, Catania M, Emelin JK, Roper SN, DeClue JE (1998) Tuberous sclerosis-related gene expression in normal and dysplastic brain. Epilepsy Res 32:12-23. (Pubitemid 28419474)
-
(1998)
Epilepsy Research
, vol.32
, Issue.1-2
, pp. 12-23
-
-
Vinters, H.V.1
Kerfoot, C.2
Catania, M.3
Emelin, J.K.4
Roper, S.N.5
Declue, J.E.6
-
41
-
-
46649087778
-
Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway
-
Wang B, Xiao Z, Chen B, Han J, Gao Y, Zhang J, Zhao W, Wang X, Dai J (2008) Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway. PLoS One 3:e1856.
-
(2008)
PLoS One
, vol.3
-
-
Wang, B.1
Xiao, Z.2
Chen, B.3
Han, J.4
Gao, Y.5
Zhang, J.6
Zhao, W.7
Wang, X.8
Dai, J.9
-
42
-
-
77952525264
-
High glucose induces differentiation and adipogenesis in porcine muscle satellite cells via mTOR
-
Yue T, Yin J, Li F, Li D, Du M (2010) High glucose induces differentiation and adipogenesis in porcine muscle satellite cells via mTOR. BMB Rep 43:140-145.
-
(2010)
BMB Rep
, vol.43
, pp. 140-145
-
-
Yue, T.1
Yin, J.2
Li, F.3
Li, D.4
Du, M.5
|