-
1
-
-
48249087666
-
Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells
-
Akar U, Chaves-Reyez A, Barria M, Tari A, Sanguino A, Kondo Y, Kondo S, Arun B, Lopez-Berestein G, Ozpolat B. 2008. Silencing of Bcl-2 expression by small interfering RNA induces autophagic cell death in MCF-7 breast cancer cells. Autophagy 4(5):669-679.
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 669-679
-
-
Akar, U.1
Chaves-Reyez, A.2
Barria, M.3
Tari, A.4
Sanguino, A.5
Kondo, Y.6
Kondo, S.7
Arun, B.8
Lopez-Berestein, G.9
Ozpolat, B.10
-
2
-
-
84864290306
-
IFN-gamma-inducible Irga6 mediate host resistance against Chlamydia trachomatis via autophagy
-
Al-Zeer MA, Al-Younes AI, Braun PR, Zerrahn J, Meyer TF. 2009. IFN-gamma-inducible Irga6 mediate host resistance against Chlamydia trachomatis via autophagy. PLoS One 4(2):e4588.
-
(2009)
PLoS One
, vol.4
, Issue.2
-
-
Al-Zeer, M.A.1
Al-Younes, A.I.2
Braun, P.R.3
Zerrahn, J.4
Meyer, T.F.5
-
3
-
-
84877344922
-
IFNbeta1/interferon-beta-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function
-
Ambjørn M, Ejlerskov P, Liu Y, Lees M, Jäätelä M, Issazadeh-Navikas S. 2013. IFNbeta1/interferon-beta-induced autophagy in MCF-7 breast cancer cells counteracts its proapoptotic function. Autophagy 9(3):287-302.
-
(2013)
Autophagy
, vol.9
, Issue.3
, pp. 287-302
-
-
Ambjørn, M.1
Ejlerskov, P.2
Liu, Y.3
Lees, M.4
Jäätelä, M.5
Issazadeh-Navikas, S.6
-
4
-
-
0035929650
-
Tumor suppressor PTEN positively regulate macrophagy by inhibiting the phosphatidylinositol 3-kinase/protein B pathway
-
Arico S. 2001. Tumor suppressor PTEN positively regulate macrophagy by inhibiting the phosphatidylinositol 3-kinase/protein B pathway. J Biol Chem 276(38):35243-35246.
-
(2001)
J Biol Chem
, vol.276
, Issue.38
, pp. 35243-35246
-
-
Arico, S.1
-
5
-
-
0038546648
-
Interferon beta promotes survival in primary astrocytes through phosphatidylinositol 3-kinase
-
DOI 10.1016/S0165-5728(03)00160-7
-
Barca O, Ferre S, Seoane M, Prieto J M, Lema M, Senaris R, Arce VM. 2003. Interferon beta promotes survival in primary astrocytes through phosphatidylinositol 3-kinase. J Neuroimmunol 139(1-2):155-159. (Pubitemid 36694401)
-
(2003)
Journal of Neuroimmunology
, vol.139
, Issue.1-2
, pp. 155-159
-
-
Barca, O.1
Ferre, S.2
Seoane, M.3
Prieto, J.M.4
Lema, M.5
Senaris, R.6
Arce, V.M.7
-
6
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
DOI 10.1016/S0968-0004(01)01958-2, PII S0968000401019582
-
Brazil DP, Hemming BA. 2001. Ten years of protein kinase B signaling: a hard Akt to follow. Trends Biochem Sci 26(11): 657-664. (Pubitemid 33042488)
-
(2001)
Trends in Biochemical Sciences
, vol.26
, Issue.11
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
7
-
-
84861865743
-
Cell-mediated autophagy promotes cancer cell survival
-
Buchser W-J, Laskow T-C, Pavlik P-J, Lin H-M, Lotze M-T. 2012. Cell-mediated autophagy promotes cancer cell survival. Cancer Res 72(12):2978-2979.
-
(2012)
Cancer Res
, vol.72
, Issue.12
, pp. 2978-2979
-
-
Buchser, W.-J.1
Laskow, T.-C.2
Pavlik, P.-J.3
Lin, H.-M.4
Lotze, M.-T.5
-
8
-
-
84869057548
-
RNase L triggers autophagy in response to viral infections
-
Chakrabarti A, Ghosh PK, Banerjee S, Gaughan Ch, Silverman RH. 2012. RNase L triggers autophagy in response to viral infections. J Virol 86(20):11311-11321.
-
(2012)
J Virol
, vol.86
, Issue.20
, pp. 11311-11321
-
-
Chakrabarti, A.1
Ghosh, P.K.2
Banerjee, S.3
Gaughan, C.H.4
Silverman, R.H.5
-
9
-
-
77956508417
-
Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation
-
Chang YP, Tsai CH, Huang WC, Wang CH, Chen CH, Lin YS, Kai JI, Hsieh CH, Cheng YL, Choi PC, Chen SH, Chang SP, Liu HS, Lin CH. 2010. Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation J Biol Chem 285(37):28715-28721.
-
(2010)
J Biol Chem
, vol.285
, Issue.37
, pp. 28715-28721
-
-
Chang, Y.P.1
Tsai, C.H.2
Huang, W.C.3
Wang, C.H.4
Chen, C.H.5
Lin, Y.S.6
Kai, J.I.7
Hsieh, C.H.8
Cheng, Y.L.9
Choi, P.C.10
Chen, S.H.11
Chang, S.P.12
Liu, H.S.13
Lin, C.H.14
-
10
-
-
79251577061
-
The regulation of autophagy-unanswered questions
-
Chen Y, Klionsky DJ. 2011. The regulation of autophagy-unanswered questions. J Cell Sci 124(Pt2):161-170.
-
(2011)
J Cell Sci
, vol.124
, Issue.PART.2
, pp. 161-170
-
-
Chen, Y.1
Klionsky, D.J.2
-
11
-
-
84875748505
-
Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy
-
Cidado J, Park B-H. 2012. Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy. J Mammary Gland Biol Neoplasia 17(3-4):205-216.
-
(2012)
J Mammary Gland Biol Neoplasia
, vol.17
, Issue.3-4
, pp. 205-216
-
-
Cidado, J.1
Park, B.-H.2
-
12
-
-
70449900928
-
TOR complex 2: A signaling pathway of its own
-
Cybulski N, Hall MN. 2009. TOR complex 2: a signaling pathway of its own. Trends Biochem Sci 34(12):620-627.
-
(2009)
Trends Biochem Sci
, vol.34
, Issue.12
, pp. 620-627
-
-
Cybulski, N.1
Hall, M.N.2
-
13
-
-
0030840464
-
Stats and gene regulation
-
Darnell JE. 1997. Stats and gene regulation. Science 277(5332): 1630-1635.
-
(1997)
Science
, vol.277
, Issue.5332
, pp. 1630-1635
-
-
Darnell, J.E.1
-
14
-
-
78651253906
-
Critical role of lipid rafts in virus entry and activation of phosphoinositide 3¢ kinase/Akt signaling during early stages of Japanese encephalitis virus infection in neural stem/progenitor cells
-
Das S, Charkraborty S, Basu A. 2010. Critical role of lipid rafts in virus entry and activation of phosphoinositide 3¢ kinase/Akt signaling during early stages of Japanese encephalitis virus infection in neural stem/progenitor cells. J. Neurochem 115(2):537-549.
-
(2010)
J. Neurochem
, vol.115
, Issue.2
, pp. 537-549
-
-
Das, S.1
Charkraborty, S.2
Basu, A.3
-
15
-
-
33745357459
-
Autophagy as an immune defense mechanism
-
DOI 10.1016/j.coi.2006.05.019, PII S095279150600094X
-
Deretic V. 2006. Autophagy as an immune defense mechanism. Curr Opin Immunol 18:375-382. (Pubitemid 43947574)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.4
, pp. 375-382
-
-
Deretic, V.1
-
16
-
-
33745753573
-
Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence
-
Ehrhardt C. 2006. Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence. Cell Microbiol 8(8):1336-1348.
-
(2006)
Cell Microbiol
, vol.8
, Issue.8
, pp. 1336-1348
-
-
Ehrhardt, C.1
-
17
-
-
78149475478
-
Akt and autophagy cooperate to promote survival of drug-resistant glioma
-
Fan QW, Cheng C, Hackett C. 2010. Akt and autophagy cooperate to promote survival of drug-resistant glioma. Sci Signal 3(147):ra81.
-
(2010)
Sci Signal
, vol.3
, Issue.147
-
-
Fan, Q.W.1
Cheng, C.2
Hackett, C.3
-
18
-
-
84862528335
-
TOR pathways in human malignancies
-
Fasolo A, Sessa C, Targetin M. 2012. TOR pathways in human malignancies. Curr Pharm Des 18(19):2766-2777.
-
(2012)
Curr Pharm des
, vol.18
, Issue.19
, pp. 2766-2777
-
-
Fasolo, A.1
Sessa, C.2
Targetin, M.3
-
19
-
-
84893946175
-
Influence of IFN-a2c on growth arrest, apoptosis, and autophagy in Daudi cells
-
published abstract
-
Fey SB, Schmeisser H, Mejido J, Nie H, Tsuno T, Zoon KC. 2007. Influence of IFN-a2c on growth arrest, apoptosis, and autophagy in Daudi cells. J Interferon Cytokine Res 98:738 (published abstract).
-
(2007)
J Interferon Cytokine Res
, vol.98
, pp. 738
-
-
Fey, S.B.1
Schmeisser, H.2
Mejido, J.3
Nie, H.4
Tsuno, T.5
Zoon, K.C.6
-
20
-
-
79958700761
-
Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibition effect of resveratrol in glioma cells
-
Filippi-Chiela EC, Villodre ES, Zamin LL, Lenz G. 2011. Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibition effect of resveratrol in glioma cells. PLoS One 6(6):e20849.
-
(2011)
PLoS One
, vol.6
, Issue.6
-
-
Filippi-Chiela, E.C.1
Villodre, E.S.2
Zamin, L.L.3
Lenz, G.4
-
21
-
-
2542628931
-
Ras is involved in the negative control of autophagy through the class I PI3-kinase
-
DOI 10.1038/sj.onc.1207539
-
Furuta S, Hidaka E, Ogata A, Yokota S, Kamata T. 2004. Ras is involved in negative control of autophagy through the class I PI3-kinase. Oncogene 23(22):3898-3904. (Pubitemid 38747918)
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 3898-3904
-
-
Furuta, S.1
Hidaka, E.2
Ogata, A.3
Yokota, S.4
Kamata, T.5
-
22
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
-
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. 2004. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119(6):753-766. (Pubitemid 40017683)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
23
-
-
80053303830
-
Autophagy and cytokines
-
Harris J. 2011. Autophagy and cytokines. Cytokine 56(2):140-144.
-
(2011)
Cytokine
, vol.56
, Issue.2
, pp. 140-144
-
-
Harris, J.1
-
24
-
-
78349237370
-
Dengue virus-induced autophagy regulates lipid metabolism
-
Heaton NS and Randall G. 2010. Dengue virus-induced autophagy regulates lipid metabolism. Cell Host and Microbe 8(5):422-432.
-
(2010)
Cell Host and Microbe
, vol.8
, Issue.5
, pp. 422-432
-
-
Heaton, N.S.1
Randall, G.2
-
25
-
-
0037193474
-
DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
-
Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. 2002. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol 157(3):455-464.
-
(2002)
J Cell Biol
, vol.157
, Issue.3
, pp. 455-464
-
-
Inbal, B.1
Bialik, S.2
Sabanay, I.3
Shani, G.4
Kimchi, A.5
-
26
-
-
84872259257
-
A virological view of innate immune recognition
-
Iwasaki A. 2012. A virological view of innate immune recognition. Annu Rev Microbiol 66:177-196.
-
(2012)
Annu Rev Microbiol
, vol.66
, pp. 177-196
-
-
Iwasaki, A.1
-
27
-
-
70649096928
-
Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidilinositol 3-kinase (PI3K)
-
Jackson D, Killip MJ, Galloway CS, Russell RJ, Randall RE. 2010. Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidilinositol 3-kinase (PI3K). Virology 396(1):94-105.
-
(2010)
Virology
, vol.396
, Issue.1
, pp. 94-105
-
-
Jackson, D.1
Killip, M.J.2
Galloway, C.S.3
Russell, R.J.4
Randall, R.E.5
-
28
-
-
79952628267
-
The Beclin 1 network regulates autophagy and apoptosis
-
Kang R, Zeh HJ, Lotze MT, Tang D. 2011. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ 18(4):571-580.
-
(2011)
Cell Death Differ
, vol.18
, Issue.4
, pp. 571-580
-
-
Kang, R.1
Zeh, H.J.2
Lotze, M.T.3
Tang, D.4
-
29
-
-
30344461860
-
The p38 mitogen-activated protein kinase pathway in interferon signal transduction
-
DOI 10.1089/jir.2005.25.749
-
Katsoulidis E, Li Y, Mears H, Platanias LC. 2005. The p38 mitogen activated protein kinase pathway in interferon signal transduction. J Interferon Cytokine Res 25(12):749-756. (Pubitemid 43068486)
-
(2005)
Journal of Interferon and Cytokine Research
, vol.25
, Issue.12
, pp. 749-756
-
-
Katsoulidis, E.1
Li, Y.2
Mears, H.3
Platanias, L.C.4
-
30
-
-
42449150892
-
Role of the Akt pathway in mRNA translation of interferon-stimulated genes
-
DOI 10.1073/pnas.0710907105
-
Kaur S, Sassano A, Dolniak B, Joshi S, Majchrzak-Kita B, Baker DP, Hay N, Fish EN, Platanias LC. 2008. Role of the Akt pathway in mRNA translation of interferon-stimulated genes. Proc Natl Acad Sci USA 105(12):4808-4813. (Pubitemid 351753828)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.12
, pp. 4808-4813
-
-
Kaur, S.1
Sassano, A.2
Dolniak, B.3
Joshi, S.4
Majchrzak-Kita, B.5
Baker, D.P.6
Hay, N.7
Fish, E.N.8
Platanias, L.C.9
-
31
-
-
84861206467
-
Regulatory effects of mTORC2 complex in type i IFN signaling and in the generation of IFN responses
-
Kaur S, Sassano A, Majchrzak-Kita B, Baker DP, Su B, Fish EN, Platanias L. 2012. Regulatory effects of mTORC2 complex in type I IFN signaling and in the generation of IFN responses. Proc Natl Acad Sci USA 109(20):7723-7728.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.20
, pp. 7723-7728
-
-
Kaur, S.1
Sassano, A.2
Majchrzak-Kita, B.3
Baker, D.P.4
Su, B.5
Fish, E.N.6
Platanias, L.7
-
32
-
-
0025084603
-
Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator
-
Kessler DS, Veals SA, Fu XY, Levy DE. 1990. Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev 4(10):1753-1765.
-
(1990)
Genes Dev
, vol.4
, Issue.10
, pp. 1753-1765
-
-
Kessler, D.S.1
Veals, S.A.2
Fu, X.Y.3
Levy, D.E.4
-
33
-
-
79955777383
-
A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection
-
Kim BH, Shenoy AR, Kumar P, Das R, Tiwari S, MacMicking JD. 2011. A family of IFN-gamma-inducible 65-kD GTPases protects against bacterial infection. Science 332(6030):717-721.
-
(2011)
Science
, vol.332
, Issue.6030
, pp. 717-721
-
-
Kim, B.H.1
Shenoy, A.R.2
Kumar, P.3
Das, R.4
Tiwari, S.5
MacMicking, J.D.6
-
34
-
-
56749170677
-
Autophagy cell death: The story of a misnomer
-
Kroemer G, Levine B. 2008. Autophagy cell death: the story of a misnomer. Nat Rev Mol Cell Biol 9(12):1004-1010.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.12
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
35
-
-
74049101149
-
Autophagy in cutaneous malignant melanoma
-
Lazova R, Klump V, Pawelek J. 2009. Autophagy in cutaneous malignant melanoma. J Cutan Pathol 37(2):256-268.
-
(2009)
J Cutan Pathol
, vol.37
, Issue.2
, pp. 256-268
-
-
Lazova, R.1
Klump, V.2
Pawelek, J.3
-
36
-
-
20744441155
-
Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stages of virus infection
-
Lee CJ, Liao CL, Lin YL. 2005. Flavivirus activates phosphatidylinositol 3-kinase signaling to block caspase-dependent apoptotic cell death at the early stages of virus infection. J Virol 79(13):8388-8399.
-
(2005)
J Virol
, vol.79
, Issue.13
, pp. 8388-8399
-
-
Lee, C.J.1
Liao, C.L.2
Lin, Y.L.3
-
37
-
-
33947134377
-
Autophagy dependent viral recognition by plasmocytoid dendritic cells
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. 2007. Autophagy dependent viral recognition by plasmocytoid dendritic cells. Science 315(5817):1398-1400.
-
(2007)
Science
, vol.315
, Issue.5817
, pp. 1398-1400
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
38
-
-
84877344662
-
The NLR protein, NLRX1 and its partner TUFM reduce type i interferon, and enhance autophagy
-
Lei Y, Wen H, Ting JPY. 2013. The NLR protein, NLRX1 and its partner TUFM reduce type I interferon, and enhance autophagy. Autophagy 9(3):1-2.
-
(2013)
Autophagy
, vol.9
, Issue.3
, pp. 1-2
-
-
Lei, Y.1
Wen, H.2
Ting, J.P.Y.3
-
39
-
-
84863005844
-
The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type i interferon and autophagy
-
Lei Y, Wen H, Yu Y, Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen K-W, Damania B, Moore ChB, Giguere PM, Siderovski DP, Hiscott J, Razani B, Semenkovich CF, Chen X, Ting JPY. 2012. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy. Immunity 36(6):933-946.
-
(2012)
Immunity
, vol.36
, Issue.6
, pp. 933-946
-
-
Lei, Y.1
Wen, H.2
Yu, Y.3
Taxman, D.J.4
Zhang, L.5
Widman, D.G.6
Swanson, K.V.7
Wen, K.-W.8
Damania, B.9
Chb, M.10
Giguere, P.M.11
Siderovski, D.P.12
Hiscott, J.13
Razani, B.14
Semenkovich, C.F.15
Chen, X.16
Jpy, T.17
-
40
-
-
0025243645
-
Interferon-dependent transcriptional activation: Signal transduction without second messenger involvement?
-
Levy D, Darnell JE, Jr. 1990. Interferon-dependent transcriptional activation: signal transduction without second messenger involvement? New Biol 2(10):923-928.
-
(1990)
New Biol
, vol.2
, Issue.10
, pp. 923-928
-
-
Levy, D.1
Darnell Jr., J.E.2
-
41
-
-
84865508002
-
Interferongamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon regulatory factor-1 (IRF-1)
-
Li P, Du Q, Cao Z, Guo Z, Evankovich J, Yan W, Chang Y, Shao L, Stolz DB, Tsung A, Geller DA. 2012. Interferongamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon regulatory factor-1 (IRF-1). Cancer Lett 314(2):213-222.
-
(2012)
Cancer Lett
, vol.314
, Issue.2
, pp. 213-222
-
-
Li, P.1
Du, Q.2
Cao, Z.3
Guo, Z.4
Evankovich, J.5
Yan, W.6
Chang, Y.7
Shao, L.8
Stolz, D.B.9
Tsung, A.10
Geller, D.A.11
-
42
-
-
84887270621
-
Suppression of autophagy enhanced growth inhibition and apoptosis of interferon-beta in human glioma cells
-
Li Y, Zhu H, Zeng X, Fan J, Qian X, Wang S, Wang Z, Sun Y, Wang X, Wang W, Ju D. 2013. Suppression of autophagy enhanced growth inhibition and apoptosis of interferon-beta in human glioma cells. Mol Neurobiol 47(3):1000-1010.
-
(2013)
Mol Neurobiol
, vol.47
, Issue.3
, pp. 1000-1010
-
-
Li, Y.1
Zhu, H.2
Zeng, X.3
Fan, J.4
Qian, X.5
Wang, S.6
Wang, Z.7
Sun, Y.8
Wang, X.9
Wang, W.10
Ju, D.11
-
43
-
-
84867688629
-
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
-
Litvak V, Ratushny AV, Lampano AE, Schmitz F, Huang AC, Raman A, Rust AG, Bergthaler A, Aitchison JD, Aderem A. 2012. A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature 490(7420): 421-425.
-
(2012)
Nature
, vol.490
, Issue.7420
, pp. 421-425
-
-
Litvak, V.1
Ratushny, A.V.2
Lampano, A.E.3
Schmitz, F.4
Huang, A.C.5
Raman, A.6
Rust, A.G.7
Bergthaler, A.8
Aitchison, J.D.9
Aderem, A.10
-
44
-
-
67349217986
-
Molecular mechanisms of mTORmediated translation control
-
Ma XM, Blenis J. 2009. Molecular mechanisms of mTORmediated translation control. Nat Rev Mol Cell Biol 10(5): 307-318.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, Issue.5
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
45
-
-
34548188741
-
Self-eating and self-killing: Crosstalk between autophagy and apoptosis
-
DOI 10.1038/nrm2239, PII NRM2239
-
Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. 2007. Selfeating and self killing: crosstalk between autophagy and apoptosis. Nat Rev 8(9):741-752. (Pubitemid 47312826)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.9
, pp. 741-752
-
-
Maiuri, M.C.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
46
-
-
23744516268
-
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
-
DOI 10.1101/gad.1314605
-
Manning B-D, Logsdon MN, Lipovsky AI, Abbott D, Kwiatkowski DJ, Cantley LC. 2005. Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2. Genes Dev 19(15):1773-1778. (Pubitemid 41126916)
-
(2005)
Genes and Development
, vol.19
, Issue.15
, pp. 1773-1778
-
-
Manning, B.D.1
Logsdon, M.N.2
Lipovsky, A.I.3
Abbott, D.4
Kwiatkowski, D.J.5
Cantley, L.C.6
-
47
-
-
84863610034
-
IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway
-
Matsuzawa T, Kim BH, Shenoy AR, Kamitani S, Miyake M, Macmicking JD. 2012. IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway. J Immunol 189(2):813-818.
-
(2012)
J Immunol
, vol.189
, Issue.2
, pp. 813-818
-
-
Matsuzawa, T.1
Kim, B.H.2
Shenoy, A.R.3
Kamitani, S.4
Miyake, M.5
MacMicking, J.D.6
-
48
-
-
84862506183
-
Apoptosis-inducing factor (AIF) is targeted in IFN-alpha2ainduced Bid-mediated apoptosis through Bak activation in ovarian cancer cells
-
Miyake K, Bekisz J, Zhao T, Clark CR, Zoon K. 2012. Apoptosis-inducing factor (AIF) is targeted in IFN-alpha2ainduced Bid-mediated apoptosis through Bak activation in ovarian cancer cells. Biochim Biophys Acta 1823(2):1378-1388.
-
(1823)
Biochim Biophys Acta
, Issue.2
, pp. 1378-1388
-
-
Miyake, K.1
Bekisz, J.2
Zhao, T.3
Clark, C.R.4
Zoon, K.5
-
49
-
-
0035823494
-
Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression
-
Nguyen H, Ramana CV, Bayes J, Stark GR. 2001. Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression. J Biol Chem 276(36):33361-33368.
-
(2001)
J Biol Chem
, vol.276
, Issue.36
, pp. 33361-33368
-
-
Nguyen, H.1
Ramana, C.V.2
Bayes, J.3
Stark, G.R.4
-
50
-
-
79951607477
-
Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis
-
Oh S, Xiaofei E, Ni D, Pirooz SD, Lee JY, Lee D, Zhao Z, Lee S, Lee H, Ku B, Kowalik T, Martin SE, Oh BH, Jung JU, Liang C. 2011. Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis. Cell Death Differ 18(3):452-464.
-
(2011)
Cell Death Differ
, vol.18
, Issue.3
, pp. 452-464
-
-
Oh, S.1
Xiaofei, E.2
Ni, D.3
Pirooz, S.D.4
Lee, J.Y.5
Lee, D.6
Zhao, Z.7
Lee, S.8
Lee, H.9
Ku, B.10
Kowalik, T.11
Martin, S.E.12
Oh, B.H.13
Jung, J.U.14
Liang, C.15
-
51
-
-
82555187810
-
Image-based genome-wide siRNA screen identifies selective autophagy factors
-
Orvedahl A, Sumpter Jr R, Xiao, G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin Ch, Sun Q, Roth M, Forst CV, Wrana JL, Zhang YE, Luby-Phelps K, Xavier RJ, Xie Y, Levine B. 2011. Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 480(7375):113-117.
-
(2011)
Nature
, vol.480
, Issue.7375
, pp. 113-117
-
-
Orvedahl, A.1
Sumpter Jr., R.2
Xiao, G.3
Ng, A.4
Zou, Z.5
Tang, Y.6
Narimatsu, M.7
Ch, G.8
Sun, Q.9
Roth, M.10
Forst, C.V.11
Wrana, J.L.12
Zhang, Y.E.13
Luby-Phelps, K.14
Xavier, R.J.15
Xie, Y.16
Levine, B.17
-
52
-
-
84893916886
-
IRF-8 regulates autophagy and activates microglia to exacerbate neuroinflammation
-
published abstract
-
Ozato K, Yoshimi R, Yoshida Y, Gupta M, Yoshii H, Munasinghe J, Maximova O, Xiong H, Wang H, Morse HC. 2013. IRF-8 regulates autophagy and activates microglia to exacerbate neuroinflammation. Cytokine 63:288 (published abstract).
-
(2013)
Cytokine
, vol.63
, pp. 288
-
-
Ozato, K.1
Yoshimi, R.2
Yoshida, Y.3
Gupta, M.4
Yoshii, H.5
Munasinghe, J.6
Maximova, O.7
Xiong, H.8
Wang, H.9
Morse, H.C.10
-
53
-
-
18844457095
-
Mechanisms of Type i and Type II interferon mediated signaling
-
Platanias LC. 2005. Mechanisms of Type I and Type II interferon mediated signaling. Nature Rev Immunol 5(5):375-386.
-
(2005)
Nature Rev Immunol
, vol.5
, Issue.5
, pp. 375-386
-
-
Platanias, L.C.1
-
54
-
-
81455135819
-
Activation of autophagy by alpha-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes
-
Rasmussen SB, Horan KA, Holm ChK, Stranks AJ, Mettenleiter TC, Simon AK, Jensen SB, Rixon FJ, He B, Paludan SR. 2011. Activation of autophagy by alpha-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes. J Immunol 187(10):5268-5276.
-
(2011)
J Immunol
, vol.187
, Issue.10
, pp. 5268-5276
-
-
Rasmussen, S.B.1
Horan, K.A.2
Chk, H.3
Stranks, A.J.4
Mettenleiter, T.C.5
Simon, A.K.6
Jensen, S.B.7
Rixon, F.J.8
He, B.9
Paludan, S.R.10
-
55
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
DOI 10.1038/370527a0
-
Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J. 1994. Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature 370(6490):527-532. (Pubitemid 24264918)
-
(1994)
Nature
, vol.370
, Issue.6490
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.J.6
Waterfield, M.D.7
Downward, J.8
-
56
-
-
0034814964
-
Interferon-α promotes survival of human primary B-lymphocytes via phosphatidylinositol 3-kinase
-
DOI 10.1006/bbrc.2001.5025
-
Ruuth K, Carlsson L, Hallberg B, Lundgren E. 2001. Interferona promotes survival of human primary B-lymphocytes via phosphatidylinositol 3-kinase. Biochem Biophys Res Commun 284(3):583-586. (Pubitemid 32924768)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.284
, Issue.3
, pp. 583-586
-
-
Ruuth, K.1
Carlsson, L.2
Hallberg, B.3
Lundgren, E.4
-
57
-
-
0026770248
-
Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
-
Schindler C, Shuai K, Prezioso VR, Darnell JE, Jr. 1992. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 257(5071):809-813.
-
(1992)
Science
, vol.257
, Issue.5071
, pp. 809-813
-
-
Schindler, C.1
Shuai, K.2
Prezioso, V.R.3
Darnell Jr., J.E.4
-
58
-
-
84877333758
-
Type i interferons induce autophagy in certain human cancer cell lines
-
Schmeisser H, Fey SB, Horowitz J, Fischer ER, Balinsky CA, Miyake K, Bekisz J, Snow AL, Zoon KC. 2013. Type I interferons induce autophagy in certain human cancer cell lines. Autophagy 9(5):683-696.
-
(2013)
Autophagy
, vol.9
, Issue.5
, pp. 683-696
-
-
Schmeisser, H.1
Fey, S.B.2
Horowitz, J.3
Fischer, E.R.4
Balinsky, C.A.5
Miyake, K.6
Bekisz, J.7
Snow, A.L.8
Zoon, K.C.9
-
59
-
-
34447629523
-
Innate and Adaptive Immunity through Autophagy
-
DOI 10.1016/j.immuni.2007.07.004, PII S1074761307003408
-
Schmid D, Munz C. 2007. Innate and adoptive immunity through autophagy. Immunity 27(1):11-21. (Pubitemid 47089030)
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 11-21
-
-
Schmid, D.1
Munz, C.2
-
60
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
DOI 10.1126/science.1129577
-
Singh SB, Davis AS, Deretic V. 2006. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 313(5792):1438-1441. (Pubitemid 44360272)
-
(2006)
Science
, vol.313
, Issue.5792
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
61
-
-
0031657551
-
How cells respond to interferons
-
DOI 10.1146/annurev.biochem.67.1.227
-
Stark GR, Kerr IM, Williams BRG, Silverman RH, Schreiber RD. 1998. How cells respond to interferons. Annu Rev Biochem 67:227-264. (Pubitemid 28411130)
-
(1998)
Annual Review of Biochemistry
, vol.67
, pp. 227-264
-
-
Stark, G.R.1
Kerr, I.M.2
Williams, B.R.G.3
Silverman, R.H.4
Schreiber, R.D.5
-
62
-
-
80655134724
-
Tug-of-war between HCV and the host
-
Sun J, Mayura MD, Soong L, Ou JHJ. 2011. Tug-of-war between HCV and the host. Autophagy 7(11):1394-1396.
-
(2011)
Autophagy
, vol.7
, Issue.11
, pp. 1394-1396
-
-
Sun, J.1
Mayura, M.D.2
Soong, L.3
Ou, J.H.J.4
-
63
-
-
37349038547
-
Akt plays a critical role in replication of nonsegmented negative-stranded RNA viruses
-
DOI 10.1128/JVI.01520-07
-
Sun M, Fuentes SM, Timani K, Sun D, Murphy Ch, Lin Y, August A, Teng MN, He B. 2008. Akt plays a critical role in replication of non-segmented negative-stranded RNA viruses. J Virol 82(1):105-114. (Pubitemid 350309128)
-
(2008)
Journal of Virology
, vol.82
, Issue.1
, pp. 105-114
-
-
Sun, M.1
Fuentes, S.M.2
Timani, K.3
Sun, D.4
Murphy, C.5
Lin, Y.6
August, A.7
Teng, M.N.8
He, B.9
-
64
-
-
33644609471
-
PKR-dependent autophagic degradation of herpes simplex virus type 1
-
Talloczy Z, Virgin HW, Levine B. 2006. PKR-dependent autophagic degradation of herpes simplex virus type 1. Autophagy 2(1):24-29.
-
(2006)
Autophagy
, vol.2
, Issue.1
, pp. 24-29
-
-
Talloczy, Z.1
Virgin, H.W.2
Levine, B.3
-
65
-
-
35148815242
-
Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy
-
Tasdemir E, Maiuri MC, Tajeddine N, Vitale I, Criollo A, Vicencio JM, Hickman JA, Geneste O, Kroemer G. 2007. Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy. Cell Cycle 6(18):2263-2267. (Pubitemid 47547704)
-
(2007)
Cell Cycle
, vol.6
, Issue.18
, pp. 2263-2267
-
-
Tasdemir, E.1
Maiuri, M.C.2
Tajeddine, N.3
Vitale, I.4
Criollo, A.5
Vicencio, J.M.6
Hickman, J.A.7
Geneste, O.8
Kroemer, G.9
-
66
-
-
0035851205
-
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells
-
Tremblay F, Marette A. 2001. Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells. J Biol Chem 276(21):38052-38060.
-
(2001)
J Biol Chem
, vol.276
, Issue.21
, pp. 38052-38060
-
-
Tremblay, F.1
Marette, A.2
-
67
-
-
84155167173
-
BID is a critical factor controlling cell viability regulated by IFN-alpha
-
Tsuno T, Mejido J, Zhao T, Phillips T, Myers TG, Bekisz J, Zoon KC. 2012. BID is a critical factor controlling cell viability regulated by IFN-alpha. J Immunother 35(1):23-31.
-
(2012)
J Immunother
, vol.35
, Issue.1
, pp. 23-31
-
-
Tsuno, T.1
Mejido, J.2
Zhao, T.3
Phillips, T.4
Myers, T.G.5
Bekisz, J.6
Zoon, K.C.7
-
68
-
-
0028982917
-
IFN-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3¢-kinase
-
Uddin S. 1995. IFN-alpha engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3¢-kinase. J Biol Chem 270(27):15938-159341.
-
(1995)
J Biol Chem
, vol.270
, Issue.27
, pp. 15938-159341
-
-
Uddin, S.1
-
69
-
-
84866019998
-
PI3K and STAT3: A new alliance
-
Vogt PK, Hart JR. 2011. PI3K and STAT3: A new alliance. Cancer Discov 1(6):481-486.
-
(2011)
Cancer Discov
, vol.1
, Issue.6
, pp. 481-486
-
-
Vogt, P.K.1
Hart, J.R.2
-
70
-
-
84874192375
-
FOXO3A directs a protective autophagy program in hematopoietic stem cells
-
Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, Debnath J, Passegue E. 2013. FOXO3A directs a protective autophagy program in hematopoietic stem cells. Nature 494(7437):33-327.
-
(2013)
Nature
, vol.494
, Issue.7437
, pp. 33-327
-
-
Warr, M.R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
Debnath, J.7
Passegue, E.8
-
71
-
-
32044465506
-
TOR in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN 2006. TOR signaling in growth and metabolism. Cell 124(3):5-19.
-
(2006)
Cell
, vol.124
, Issue.3
, pp. 5-19
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
72
-
-
0035957951
-
Interferon a/b promotes cell survival by activating nuclear factor kB through phosphatidylinositol 3-kinase Akt
-
Yang CH, Murti A, Pfeffer SR, Kim JG, Donner DB, Pfeffer LM. 2001. Interferon a/b promotes cell survival by activating nuclear factor kB through phosphatidylinositol 3-kinase Akt. J Biol Chem 276(17):13756-13761.
-
(2001)
J Biol Chem
, vol.276
, Issue.17
, pp. 13756-13761
-
-
Yang, C.H.1
Murti, A.2
Pfeffer, S.R.3
Kim, J.G.4
Donner, D.B.5
Pfeffer, L.M.6
-
73
-
-
79952229430
-
Pancreatic cancer requires autophagy for tumor growth
-
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H. 2011. Pancreatic cancer requires autophagy for tumor growth. Genes Dev 25(7):717-729.
-
(2011)
Genes Dev
, vol.25
, Issue.7
, pp. 717-729
-
-
Yang, S.1
Wang, X.2
Contino, G.3
Liesa, M.4
Sahin, E.5
Ying, H.6
-
74
-
-
54849188100
-
LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers
-
Yoshioka A. 2008. LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers. Int. J Oncol 33(3):461-468.
-
(2008)
Int J Oncol
, vol.33
, Issue.3
, pp. 461-468
-
-
Yoshioka, A.1
-
75
-
-
2642553881
-
Regulation of an ATG7-beclin 1 program of autophaglic cell death by caspase-8
-
DOI 10.1126/science.1096645
-
Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, Baehrecke EH, Lenardo MJ. 2004. Regulation of an ATG-7 beclin program of autophagic cell death by caspase-8. Science 304(5676):1500-1502. (Pubitemid 38720930)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
Dutt, P.4
Freundt, E.5
Welsh, S.6
Baehrecke, E.H.7
Lenardo, M.J.8
-
76
-
-
51849111556
-
PI3K pathway alterations in cancer: Variations in a theme
-
Yuan TL, Cantley LC. 2008. PI3K pathway alterations in cancer: variations in a theme. Oncogene 27(41):5497-5510.
-
(2008)
Oncogene
, vol.27
, Issue.41
, pp. 5497-5510
-
-
Yuan, T.L.1
Cantley, L.C.2
-
77
-
-
34250828457
-
Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling
-
DOI 10.1007/s10495-007-0071-y
-
Zhirnov OP, Klenk HD. 2007. Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling. Apoptosis 12(8):1419-1432. (Pubitemid 46988278)
-
(2007)
Apoptosis
, vol.12
, Issue.8
, pp. 1419-1432
-
-
Zhirnov, O.P.1
Klenk, H.-D.2
-
78
-
-
84859061111
-
Production of interferon alpha by human immunodeficiency virus type 1 in human plasmocytoid dendritic cells is dependent on induction of autophagy
-
Zhou D, Kang KH, Spector SA. 2012. Production of interferon alpha by human immunodeficiency virus type 1 in human plasmocytoid dendritic cells is dependent on induction of autophagy. J Infect Dis 205(8):1258-1267.
-
(2012)
J Infect Dis
, vol.205
, Issue.8
, pp. 1258-1267
-
-
Zhou, D.1
Kang, K.H.2
Spector, S.A.3
-
79
-
-
84877337914
-
Inhibition autophagy potentiates the anticancer activity of IFN1 IFNalpha in chronic myeloid leukemia cells
-
Zhu S, Cao L, Yu Y, Yang L, Yang M, Liu K, Huang J, Kang R, Livesey KM, Tang D. 2013. Inhibition autophagy potentiates the anticancer activity of IFN1 IFNalpha in chronic myeloid leukemia cells. Autophagy 9(3):317-327.
-
(2013)
Autophagy
, vol.9
, Issue.3
, pp. 317-327
-
-
Zhu, S.1
Cao, L.2
Yu, Y.3
Yang, L.4
Yang, M.5
Liu, K.6
Huang, J.7
Kang, R.8
Livesey, K.M.9
Tang, D.10
-
80
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
Zoncu R, Efeyan A, Sabatini DM. 2011. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12(1):21-35.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, Issue.1
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
|