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Volumn 8, Issue 8, 2006, Pages 1336-1348

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON REGULATORY FACTOR 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; VIRUS PROTEIN; VIRUS RNA;

EID: 33745753573     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2006.00713.x     Document Type: Article
Times cited : (205)

References (46)
  • 2
    • 10344259136 scopus 로고    scopus 로고
    • The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter
    • Andrejeva, J., Childs, K. S., Young, D. F., Carlos, T. S., Stock, N., Goodbourn, S., and Randall, R. E. (2004) The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter. Proc Natl Acad Sci USA 101: 17264-17269.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17264-17269
    • Andrejeva, J.1    Childs, K.S.2    Young, D.F.3    Carlos, T.S.4    Stock, N.5    Goodbourn, S.6    Randall, R.E.7
  • 3
    • 0027432424 scopus 로고
    • Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
    • Arcaro, A., and Wymann, M. P. (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J 296: 297-301.
    • (1993) Biochem J , vol.296 , pp. 297-301
    • Arcaro, A.1    Wymann, M.P.2
  • 5
    • 2342565881 scopus 로고    scopus 로고
    • Advances in protein kinase B signalling: AKTion on multiple fronts
    • Brazil, D. P., Yang, Z. Z., and Hemmings, B. A. (2004) Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem Sci 29: 233-242.
    • (2004) Trends Biochem Sci , vol.29 , pp. 233-242
    • Brazil, D.P.1    Yang, Z.Z.2    Hemmings, B.A.3
  • 6
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L. C. (2002) The phosphoinositide 3-kinase pathway. Science 296: 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 7
    • 0034769142 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase
    • Chen, X., and Wang, Z. (2001a) Regulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase. EMBO Rep 2: 842-849.
    • (2001) EMBO Rep , vol.2 , pp. 842-849
    • Chen, X.1    Wang, Z.2
  • 8
    • 0035093445 scopus 로고    scopus 로고
    • Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity
    • Chen, X., and Wang, Z. (2001b) Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activity. EMBO Rep 2: 68-74.
    • (2001) EMBO Rep , vol.2 , pp. 68-74
    • Chen, X.1    Wang, Z.2
  • 9
    • 0027953284 scopus 로고
    • PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity
    • Dhand, R., Hiles, I., Panayotou, G., Roche, S., Fry, M. J., Gout, I., et al. (1994) PI 3-kinase is a dual specificity enzyme: Autoregulation by an intrinsic protein-serine kinase activity. EMBO J 13: 522-533.
    • (1994) EMBO J , vol.13 , pp. 522-533
    • Dhand, R.1    Hiles, I.2    Panayotou, G.3    Roche, S.4    Fry, M.J.5    Gout, I.6
  • 10
    • 2942624370 scopus 로고    scopus 로고
    • Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3
    • Ehrhardt, C., Kardinal, C., Wurzer, W. J., Wolff, T., von Eichel-Streiber, C., Pleschka, S., et al. (2004) Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3. FEBS Lett 567: 230-238.
    • (2004) FEBS Lett , vol.567 , pp. 230-238
    • Ehrhardt, C.1    Kardinal, C.2    Wurzer, W.J.3    Wolff, T.4    von Eichel-Streiber, C.5    Pleschka, S.6
  • 12
    • 0036720769 scopus 로고    scopus 로고
    • A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs
    • Fodor, E., Crow, M., Mingay, L. J., Deng, T., Sharps, J., Fechter, P., and Brownlee, G. G. (2002) A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase inhibits endonucleolytic cleavage of capped RNAs. J Virol 76: 8989-9001.
    • (2002) J Virol , vol.76 , pp. 8989-9001
    • Fodor, E.1    Crow, M.2    Mingay, L.J.3    Deng, T.4    Sharps, J.5    Fechter, P.6    Brownlee, G.G.7
  • 16
    • 0033572662 scopus 로고    scopus 로고
    • The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo
    • Gray, A., Van Der Kaay, J., and Downes, C. P. (1999) The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo. Biochem J 344 Part 3: 929-936.
    • (1999) Biochem J , vol.344 , Issue.PART 3 , pp. 929-936
    • Gray, A.1    Van Der Kaay, J.2    Downes, C.P.3
  • 17
    • 14044267522 scopus 로고    scopus 로고
    • Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus
    • Guillot, L., Le Goffic, R., Bloch, S., Escriou, N., Akira, S., Chignard, M., and Si-Tahar, M. (2005) Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J Biol Chem 280: 5571-5580.
    • (2005) J Biol Chem , vol.280 , pp. 5571-5580
    • Guillot, L.1    Le Goffic, R.2    Bloch, S.3    Escriou, N.4    Akira, S.5    Chignard, M.6    Si-Tahar, M.7
  • 19
    • 28844462293 scopus 로고    scopus 로고
    • Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC
    • Helms, M. N., Liu, L., Liang, Y. Y., Al-Khalili, O., Vandewalle, A., Saxena, S., et al. (2005) Phosphatidylinositol 3,4,5-trisphosphate mediates aldosterone stimulation of epithelial sodium channel (ENaC) and interacts with gamma-ENaC. J Biol Chem 280: 40885-40891.
    • (2005) J Biol Chem , vol.280 , pp. 40885-40891
    • Helms, M.N.1    Liu, L.2    Liang, Y.Y.3    Al-Khalili, O.4    Vandewalle, A.5    Saxena, S.6
  • 21
    • 22544455673 scopus 로고    scopus 로고
    • Cell type-specific involvement of RIG-I in antiviral response
    • Kato, H., Sato, S., Yoneyama, M., Yamamoto, M., Uematsu, S., Matsui, K., et al. (2005) Cell type-specific involvement of RIG-I in antiviral response. Immunity 23: 19-28.
    • (2005) Immunity , vol.23 , pp. 19-28
    • Kato, H.1    Sato, S.2    Yoneyama, M.3    Yamamoto, M.4    Uematsu, S.5    Matsui, K.6
  • 22
    • 0032828271 scopus 로고    scopus 로고
    • A fatal relationship - Influenza virus interactions with the host cell
    • Ludwig, S., Pleschka, S., and Wolff, T. (1999) A fatal relationship -influenza virus interactions with the host cell. Viral Immunol 12: 175-196.
    • (1999) Viral Immunol , vol.12 , pp. 175-196
    • Ludwig, S.1    Pleschka, S.2    Wolff, T.3
  • 23
    • 0035815684 scopus 로고    scopus 로고
    • Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway
    • Ludwig, S., Ehrhardt, C., Neumeier, E. R., Kracht, M., Rapp, U. R., and Pleschka, S. (2001) Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway. J Biol Chem 276: 10990-10998.
    • (2001) J Biol Chem , vol.276 , pp. 10990-10998
    • Ludwig, S.1    Ehrhardt, C.2    Neumeier, E.R.3    Kracht, M.4    Rapp, U.R.5    Pleschka, S.6
  • 24
    • 0036838725 scopus 로고    scopus 로고
    • The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors
    • Ludwig, S., Wang, X., Ehrhardt, C., Zheng, H., Donelan, N., Planz, O., et al. (2002) The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors. J Virol 76: 11166-11171.
    • (2002) J Virol , vol.76 , pp. 11166-11171
    • Ludwig, S.1    Wang, X.2    Ehrhardt, C.3    Zheng, H.4    Donelan, N.5    Planz, O.6
  • 25
    • 0037295292 scopus 로고    scopus 로고
    • Influenza-virus-induced signaling cascades: Targets for antiviral therapy?
    • Ludwig, S., Planz, O., Pleschka, S., and Wolff, T. (2003) Influenza-virus-induced signaling cascades: Targets for antiviral therapy? Trends Mol Med 9: 46-52.
    • (2003) Trends Mol Med , vol.9 , pp. 46-52
    • Ludwig, S.1    Planz, O.2    Pleschka, S.3    Wolff, T.4
  • 26
    • 0032537835 scopus 로고    scopus 로고
    • Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes
    • Mills, I. G., Jones, A. T., and Clague, M. J. (1998) Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes. Curr Biol 8: 881-884.
    • (1998) Curr Biol , vol.8 , pp. 881-884
    • Mills, I.G.1    Jones, A.T.2    Clague, M.J.3
  • 27
    • 23144450820 scopus 로고    scopus 로고
    • Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis
    • Naga Prasad, S. V., Jayatilleke, A., Madamanchi, A., and Rockman, H. A. (2005) Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis. Nat Cell Biol 7: 785-796.
    • (2005) Nat Cell Biol , vol.7 , pp. 785-796
    • Naga Prasad, S.V.1    Jayatilleke, A.2    Madamanchi, A.3    Rockman, H.A.4
  • 28
    • 84858616869 scopus 로고    scopus 로고
    • Phospholipid kinases
    • Offermanns, S., and Rosenthal, W. (eds). Heidelberg: Springer Verlag
    • Nürnberg, B. (2003) Phospholipid kinases. In Molecular Pharmacology, An Enzyclopedic Reference. Offermanns, S., and Rosenthal, W. (eds). Heidelberg: Springer Verlag, pp. 739-743.
    • (2003) Molecular Pharmacology, An Enzyclopedic Reference , pp. 739-743
    • Nürnberg, B.1
  • 29
    • 0035877577 scopus 로고    scopus 로고
    • Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha). Functions of lipid kinase-deficient PI3Kalpha in signaling
    • Pirola, L., Zvelebil, M. J., Bulgarelli-Leva, G., Van Obberghen, E., Waterfield, M. D., and Wymann, M. P. (2001) Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha). Functions of lipid kinase-deficient PI3Kalpha in signaling. J Biol Chem 276: 21544-21554.
    • (2001) J Biol Chem , vol.276 , pp. 21544-21554
    • Pirola, L.1    Zvelebil, M.J.2    Bulgarelli-Leva, G.3    Van Obberghen, E.4    Waterfield, M.D.5    Wymann, M.P.6
  • 31
    • 0035090589 scopus 로고    scopus 로고
    • Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade
    • Pleschka, S., Wolff, T., Ehrhardt, C., Hobom, G., Planz, O., Rapp, U. R., and Ludwig, S. (2001) Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade. Nat Cell Biol 3: 301-305.
    • (2001) Nat Cell Biol , vol.3 , pp. 301-305
    • Pleschka, S.1    Wolff, T.2    Ehrhardt, C.3    Hobom, G.4    Planz, O.5    Rapp, U.R.6    Ludwig, S.7
  • 32
    • 7544225495 scopus 로고    scopus 로고
    • Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
    • Sarkar, S. N., Peters, K. L., Elco, C. P., Sakamoto, S., Pal, S., and Sen, G. C. (2004) Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling. Nat Struct Mol Biol 11: 1060-1067.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1060-1067
    • Sarkar, S.N.1    Peters, K.L.2    Elco, C.P.3    Sakamoto, S.4    Pal, S.5    Sen, G.C.6
  • 33
    • 23744483354 scopus 로고    scopus 로고
    • TLR3 in antiviral immunity: Key player or bystander?
    • Schroder, M., and Bowie, A. G. (2005) TLR3 in antiviral immunity: Key player or bystander? Trends Immunol 26: 462-468.
    • (2005) Trends Immunol , vol.26 , pp. 462-468
    • Schroder, M.1    Bowie, A.G.2
  • 34
    • 0035808446 scopus 로고    scopus 로고
    • Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3
    • Servant, M. J., ten Oever, B., LePage, C., Conti, L., Gessani, S., Julkunen, I., et al. (2001) Identification of distinct signaling pathways leading to the phosphorylation of interferon regulatory factor 3. J Biol Chem 276: 355-363.
    • (2001) J Biol Chem , vol.276 , pp. 355-363
    • Servant, M.J.1    ten Oever, B.2    LePage, C.3    Conti, L.4    Gessani, S.5    Julkunen, I.6
  • 35
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma, S., tenOever, B. R., Grandvaux, N., Zhou, G. P., Lin, R., and Hiscott, J. (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300: 1148-1151.
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    tenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 36
    • 0030027394 scopus 로고    scopus 로고
    • Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin
    • Shpetner, H., Joly, M., Hartley, D., and Corvera, S. (1996) Potential sites of PI-3 kinase function in the endocytic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J Cell Biol 132: 595-605.
    • (1996) J Cell Biol , vol.132 , pp. 595-605
    • Shpetner, H.1    Joly, M.2    Hartley, D.3    Corvera, S.4
  • 37
    • 0037213578 scopus 로고    scopus 로고
    • Role of protein kinase C betaII in influenza virus entry via late endosomes
    • Sieczkarski, S. B., Brown, H. A., and Whittaker, G. R. (2003) Role of protein kinase C betaII in influenza virus entry via late endosomes. J Virol 77: 460-469.
    • (2003) J Virol , vol.77 , pp. 460-469
    • Sieczkarski, S.B.1    Brown, H.A.2    Whittaker, G.R.3
  • 39
    • 0036467492 scopus 로고    scopus 로고
    • The interferon-alpha/beta system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
    • Taniguchi, T., and Takaoka, A. (2002) The interferon-alpha/beta system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 14: 111-116.
    • (2002) Curr Opin Immunol , vol.14 , pp. 111-116
    • Taniguchi, T.1    Takaoka, A.2
  • 40
    • 0029617947 scopus 로고
    • Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
    • Thanos, D., and Maniatis, T. (1995) Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell 83: 1091-1100.
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 41
    • 26444475464 scopus 로고    scopus 로고
    • Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1
    • Unterstab, G., Ludwig, S., Anton, A., Planz, O., Dauber, B., Krappmann, D., et al. (2005) Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1. Proc Natl Acad Sci USA 102: 13640-13645.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 13640-13645
    • Unterstab, G.1    Ludwig, S.2    Anton, A.3    Planz, O.4    Dauber, B.5    Krappmann, D.6
  • 43
    • 4043067193 scopus 로고    scopus 로고
    • Gene targeting: Attention to detail
    • Vanhaesebroeck, B., Rohn, J. L., and Waterfield, M. D. (2004) Gene targeting: Attention to detail. Cell 118: 274-276.
    • (2004) Cell , vol.118 , pp. 274-276
    • Vanhaesebroeck, B.1    Rohn, J.L.2    Waterfield, M.D.3
  • 44
    • 0028170210 scopus 로고
    • A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
    • Vlahos, C. J., Matter, W. F., Hui, K. Y., and Brown, R. F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269: 5241-5248.
    • (1994) J Biol Chem , vol.269 , pp. 5241-5248
    • Vlahos, C.J.1    Matter, W.F.2    Hui, K.Y.3    Brown, R.F.4
  • 46
    • 0029965452 scopus 로고    scopus 로고
    • Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
    • Wymann, M. P., Bulgarelli-Leva, G., Zvelebil, M. J., Pirola, L., Vanhaesebroeck, B., Waterfield, M. D., and Panayotou, G. (1996) Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction. Mol Cell Biol 16: 1722-1733.
    • (1996) Mol Cell Biol , vol.16 , pp. 1722-1733
    • Wymann, M.P.1    Bulgarelli-Leva, G.2    Zvelebil, M.J.3    Pirola, L.4    Vanhaesebroeck, B.5    Waterfield, M.D.6    Panayotou, G.7


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