Roles of Phosphatidylinositol 3-Kinase in Interferon-γ-dependent Phosphorylation of STAT1 on Serine 727 and Activation of Gene Expression

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 33361-33368

  Nguyen, Hannah ^b   Ramana, Chilakamarti V ^b   Bayes, Joshua ^b   Stark, George R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DERIVATIVES; ENZYMES; GENES;

PHOSPHORYLATION;

BIOCHEMISTRY;

GAMMA INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RECEPTOR SUBUNIT; SERINE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; JAK1 PROTEIN, MOUSE; JAK2 PROTEIN, MOUSE; JANUS KINASE 1; JANUS KINASE 2; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; STAT1 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; CELL DIFFERENTIATION; GEL MOBILITY SHIFT ASSAY; GENE ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; TRANSACTIVATION; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CHEMISTRY; DOMINANT GENE; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; METABOLISM; MOUSE; NORTHERN BLOTTING; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; REPORTER GENE; TIME; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CHROMONES; DNA-BINDING PROTEINS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, DOMINANT; GENES, REPORTER; INTERFERON TYPE II; JANUS KINASE 1; JANUS KINASE 2; MICE; MORPHOLINES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SERINE; STAT1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 0035823494     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M105070200     Document Type: Article

References (74)

1. Bach, E. A., Aguet, M., and Schreiber, R. D. (1997) Annu. Rev. Immunol. 15, 563-591
2. Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H., and Schreiber, R. D. (1998) Annu. Rev. Biochem. 67, 227-264
3. Wen, Z., Zhong, Z., and Darnell, J. E., Jr. (1995) Cell 82, 241-250
4. Zhu, X., Wen, Z., Xu, L. Z., and Darnell, J. E., Jr. (1997) Mol. Cell. Biol. 17, 6618-6623
5. Kovarik, P., Stoiber, D., Novy, M., and Decker, T. (1998) EMBO J. 17, 3660-3668
6. Goh, K. C., Haque, S. J., and Williams, B. R. (1999) EMBO J. 18, 5601-5608
7. Kovarik, P., Stoiber, D., Eyers, P. A., Menghini, R., Neininger, A., Gaestel, M., Cohen, P., and Decker, T. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 13956-13961
8. Gollob, J. A., Schnipper, C. P., Murphy, E. A., Ritz, J., and Frank, D. A. (1999) J. Immunol. 162, 4472-4481
9. Su, L., Rickert, R. C., and David, M. (1999) J. Biol. Chem. 274, 31770-31774
10. Gamero, A. M., and Larner, A. C. (2000) J. Biol. Chem. 275, 16574-16578
11. Decker, T., and Kovarik, P. (2000) Oncogene 19, 2628-2637
12. Takaoka, A., Tanaka, N., Mitani, Y., Miyazaki, T., Fujii, H., Sato, M., Kovarik, P., Decker, T., Schlessinger, J., and Taniguchi, T. (1999) EMBO J. 18, 2480-2488
13. Ramana, C. V., Grammatikakis, N., Chernov, M., Nguyen, H., Goh, K. C., Williams, B. R., and Stark, G. R. (2000) EMBO J. 19, 263-272
14. Fruman, D. A., Meyers, R. E., and Cantley, L. C. (1998) Annu. Rev. Biochem. 67, 481-507
15. Wymann, M. P., and Pirola, L. (1998) Biochim. Biophys. Acta 1436, 127-150
16. Vanhaesebroeck, B., Leevers, S. J., Panayotou, G., and Waterfield, M. D. (1997) Trends Biochem. Sci. 22, 267-272
17. Coffer, P. J., Jin, J., and Woodgett, J. R. (1998) Biochem. J. 335, 1-13
18. Chan, T. O., Rittenhouse, S. E., and Tsichlis, P. N. (1999) Annu. Rev. Biochem. 68, 965-1014
19. Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. (1994) Science 264, 1415-1421
20. Parganas, E., Wang, D., Stravopodis, D., Topham, D. J., Marine, J. C., Teglund, S., Vanin, E. F., Bodner, S., Colamonici, O. R., van Deursen, J. M., Grosveld, G., and Ihle, J. N. (1998) Cell 93, 385-395
21. Guschin, D., Rogers, N., Briscoe, J., Witthuhn, B., Watling, D., Horn, F., Pellegrini, S., Yasukawa, K., Heinrich, P., and Stark, G. R. (1995) EMBO J. 14, 1421-1429
22. Farrar, M. A., Campbell, J. D., and Schreiber, R. D. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11706-11710
23. Greenlund, A. C., Farrar, M. A., Viviano, B. L., and Schreiber, R. D. (1994) EMBO J. 13, 1591-1600
24. Vignais, M. L., Sadowski, H. B., Watling, D., Rogers, N. C., and Gilman, M. (1996) Mol. Cell. Biol. 16, 1759-1769
25. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual 2nd Ed, pp. 16.33-16.36, Cold Spring Harbor University Press, Cold Spring Harbor, N. Y.
26. Royal, I., and Park, M. (1995) J. Biol. Chem. 270, 27780-27787
27. Sizemore, N., Leung, S., and Stark, G. R. (1999) Mol. Cell. Biol. 19, 4798-4805
28. Seegert, D., Strehlow, I., Klose, B., Levy, D. E., Schindler, C., and Decker, T. (1994) J. Biol. Chem. 269, 8590-8595
29. Kovarik, P., Mangold, M., Ramsauer, K., Heidari, H., Steinborn, R., Zotter, A., Levy, D. E., Müller, M., and Decker, T. (2001) EMBO J. 20, 91-100
30. Ruderman, N. B., Kapeller, R., White, M. F., and Cantley, L. C. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 1411-1415
31. Rordorf-Nikolic, T., Van Horn, D. J., Chen, D., White, M. F., and Backer, J. M. (1995) J. Biol. Chem. 270, 3662-3666
32. Rodriguez-Viciana, P., Warne, P. H., Vanhaesebroeck, B., Waterfield, M. D., and Downward, J. (1996) EMBO J. 15, 2442-2451
33. van Weeren, P. C., de Bruyn, K. M., de Vries-Smits, A. M., van Lint, J., and Burgering, B. M. (1998) J. Biol. Chem. 273, 13150-13156
34. Hu, J., Roy, S. K., Shapiro, P. S., Rodig, S. R., Reddy, S. P., Platanias, L. C., Schreiber, R. D., and Kalvakolanu, D. V. (2001) J. Biol. Chem. 276, 287-297
35. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. (1999) Cell 96, 857-868
36. Kops, G. J., de Ruiter, N. D., De Vries-Smits, A. M., Powell, D. R., Bos, J. L., and Burgering, B. M. (1999) Nature 398, 630-634
37. Guo, S., Rena, G., Cichy, S., He, X., Cohen, P., and Unterman, T. (1999) J. Biol. Chem. 274, 17184-17192
38. Rena, G., Guo, S., Cichy, S. C., Unterman, T. G., and Cohen, P. (1999) J. Biol. Chem. 274, 17179-17183
39. Biggs, W. H., Meisenhelder, J., Hunter, T., Cavenee, W. K., and Arden, K. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7421-7426
40. Madrid, L. V., Wang, C. Y., Guttridge, D. C., Schottelius, A. J., Baldwin, A. S., and Mayo, M. W. (2000) Mol. Cell. Biol 20, 1626-1638
41. Brennan, P., Babbage, J. W., Burgering, B. M., Groner, B., Reif, K., and Cantrell, D. A. (1997) Immunity 7, 679-689
42. Brennan, P., Babbage, J. W., Thomas, G., and Cantrell, D. (1999) Mol. Cell. Biol. 19, 4729-4738
43. Ginger, R. S., Dalton, E. C., Ryves, W. J., Fukuzawa, M., Williams, J. G., and Harwood, A. J. (2000) EMBO J. 19, 5483-5491
44. Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Nature 378, 785-789
45. Meili, R., Ellsworth, C., and Firtel, R. A. (2000) Curr. Biol. 10, 708-717
46. Alessi, D. R., Caudwell, F. B., Andjelkovic, M., Hemmings, B. A., and Cohen, P. (1996) FEBS Lett. 399, 333-338
47. Vanhaesebroeck, B., and Alessi, D. R. (2000) Biochem. J. 346 Pt 3, 561-576
48. Scott, P. H., Brunn, G. J., Kohn, A. D., Roth, R. A., and Lawrence, J. C. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7772-7777
49. Nave, B. T., Ouwens, M., Withers, D. J., Alessi, D. R., and Shepherd, P. R. (1999) Biochem. J. 344 Pt 2, 427-431
50. Chung, J., Uchida, E., Grammer, T. C., and Blenis, J. (1997) Mol. Cell. Biol. 17, 6508-6516
51. Burfoot, M. S., Rogers, N. C., Watling, D., Smith, J. M., Pons, S., Paonessaw, G., Pellegrini, S., White, M. F., and Kerr, I. M. (1997) J. Biol. Chem. 272, 24183-24190
52. Uddin, S., Yenush, L., Sun, X. J., Sweet, M. E., White, M. F., and Platanias, L. C. (1995) J. Biol. Chem. 270, 15938-15941
53. Uddin, S., Fish, E. N., Sher, D. A., Gardziola, C., White, M. F., and Platanias, L. C. (1997) J. Immunol. 158, 2390-2397
54. Muller, M., Laxton, C., Briscoe, J., Schindler, C., Improta, T., Darnell, J. E., Jr., Stark, G. R., and Kerr, I. M. (1993) EMBO J. 12, 4221-4228
55. Qureshi, S. A., Salditt-Georgieff, M., and Darnell, J. E., Jr. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3829-3833
56. Bluyssen, H. A., and Levy, D. E. (1997) J. Biol. Chem. 272, 4600-4605
57. Heldin, C. H., Ostman, A., and Ronnstrand, L. (1998) Biochim. Biophys. Acta 1378, F79-113
58. Platanias, L. C., and Fish, E. N. (1999) Exp. Hematol. 27, 1583-1592
59. Bowtell, D. D., and Langdon, W. Y. (1995) Oncogene 11, 1561-1567
60. Donovan, J. A., Wange, R. L., Langdon, W. Y., and Samelson, L. E. (1994) J. Biol. Chem. 269, 22921-22924
61. Fukazawa, T., Miyake, S., Band, V., and Band, H. (1996) J. Biol. Chem. 271, 14554-14559
62. Galisteo, M. L., Dikic, I., Batzer, A. G., Langdon, W. Y., and Schlessinger, J. (1995) J. Biol. Chem. 270, 20242-20245
63. Marcilla, A., Rivero-Lezcano, O. M., Agarwal, A., and Robbins, K. C. (1995) J. Biol. Chem. 270, 9115-9120
64. Meisner, H., and Czech, M. P. (1995) J. Biol. Chem. 270, 25332-25335
65. Meisner, H., Conway, B. R., Hartley, D., and Czech, M. P. (1995) Mol. Cell. Biol. 15, 3571-3578
66. Soltoff, S. P., and Cantley, L. C. (1996) J. Biol. Chem. 271, 563-567
67. Tanaka, S., Neff, L., Baron, R., and Levy, J. B. (1995) J. Biol. Chem. 270, 14347-14351
68. Wang, Y., Yeung, Y. G., Langdon, W. Y., and Stanley, E. R. (1996) J. Biol. Chem. 271, 17-20
69. Gil, M. P., Bohn, E., O'Guin, A. K., Ramana, C. V., Levine, B., Stark, G. R., Virgin, H. W., and Schreiber, R. D. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6680-6685
70. Ramana, C. V., Gil, M. P., Han, Y., Ransohoff, R. M., Schreiber, R. H., and Stark, G. R. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 6674-6679
71. Sato, S., Fujita, N., and Tsuruo, T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 10832-10837
72. Andjelkovic, M., Alessi, D. R., Meier, R., Fernandez, A., Lamb, N. J., Frech, M., Cron, P., Cohen, P., Lucocq, J. M., and Hemmings, B. A. (1997) J. Biol. Chem. 272, 31515-31524
73. Meier, R., Alessi, D. R., Cron, P., Andjelkovic, M., and Hemmings, B. A. (1997) J. Biol. Chem. 272, 30491-30497
74. Welch, H., Eguinoa, A., Stephens, L. R., and Hawkins, P. T. (1998) J. Biol. Chem. 273, 11248-11256