-
1
-
-
66949152096
-
Parkinson's disease
-
Lees AJ, Hardy J, Revesz T. Parkinson's disease. Lancet 373(9680), 2055-2066 (2009).
-
(2009)
Lancet
, vol.373
, Issue.9680
, pp. 2055-2066
-
-
Lees, A.J.1
Hardy, J.2
Revesz, T.3
-
2
-
-
65249115240
-
Cognitive impairment in incident, untreated Parkinson disease: The Norwegian ParkWest study
-
Aarsland D, Bronnick K, Larsen JP, Tysnes OB, Alves G. Cognitive impairment in incident, untreated Parkinson disease: the Norwegian ParkWest study. Neurology 72(13), 1121-1126 (2009).
-
(2009)
Neurology
, vol.72
, Issue.13
, pp. 1121-1126
-
-
Aarsland, D.1
Bronnick, K.2
Larsen, J.P.3
Tysnes, O.B.4
Alves, G.5
-
3
-
-
77954382509
-
Frequency of dementia, depression other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's disease
-
Riedel O, Klotsche J, Spottke A et al. Frequency of dementia, depression other neuropsychiatric symptoms in 1,449 outpatients with Parkinson's disease. J. Neurol. 257(7), 1073-1082 (2010).
-
(2010)
J. Neurol.
, vol.257
, Issue.7
, pp. 1073-1082
-
-
Riedel, O.1
Klotsche, J.2
Spottke, A.3
-
4
-
-
41149173996
-
The Sydney multicenter study of Parkinson's disease: The inevitability of dementia at 20 years
-
Hely MA, Reid WG, Adena MA, Halliday GM, Morris JG. The Sydney multicenter study of Parkinson's disease: the inevitability of dementia at 20 years. Mov. Disord. 23(6), 837-844 (2008).
-
(2008)
Mov. Disord.
, vol.23
, Issue.6
, pp. 837-844
-
-
Hely, M.A.1
Reid, W.G.2
Adena, M.A.3
Halliday, G.M.4
Morris, J.G.5
-
5
-
-
33144489150
-
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
-
DOI 10.1212/01.wnl.0000187889.17253.b1, PII 0000611420051227000008
-
McKeith IG, Dickson DW, Lowe J et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 65(12), 1863-1872 (2005). (Pubitemid 43970103)
-
(2005)
Neurology
, vol.65
, Issue.12
, pp. 1863-1872
-
-
McKeith, I.G.1
Dickson, D.W.2
Lowe, J.3
Emre, M.4
O'Brien, J.T.5
Feldman, H.6
Cummings, J.7
Duda, J.E.8
Lippa, C.9
Perry, E.K.10
Aarsland, D.11
Arai, H.12
Ballard, C.G.13
Boeve, B.14
Burn, D.J.15
Costa, D.16
Del Ser, T.17
Dubois, B.18
Galasko, D.19
Gauthier, S.20
Goetz, C.G.21
Gomez-Tortosa, E.22
Halliday, G.23
Hansen, L.A.24
Hardy, J.25
Iwatsubo, T.26
Kalaria, R.N.27
Kaufer, D.28
Kenny, R.A.29
Korczyn, A.30
Kosaka, K.31
Lee, V.M.Y.32
Lees, A.33
Litvan, I.34
Londos, E.35
Lopez, O.L.36
Minoshima, S.37
Mizuno, Y.38
Molina, J.A.39
Mukaetova-Ladinska, E.B.40
Pasquier, F.41
Perry, R.H.42
Schulz, J.B.43
Trojanowski, J.Q.44
Yamada, M.45
more..
-
6
-
-
0025061059
-
The Lewy body variant of Alzheimer's disease: A clinical and pathologic entity
-
Hansen L, Salmon D, Galasko D et al. The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity. Neurology 40(1), 1-8 (1990). (Pubitemid 20032882)
-
(1990)
Neurology
, vol.40
, Issue.1
, pp. 1-8
-
-
Hansen, L.1
Salmon, D.2
Galasko, D.3
Masliah, E.4
Katzman, R.5
DeTeresa, R.6
Thal, L.7
Pay, M.M.8
Hofstetter, R.9
Klauber, M.10
Rice, V.11
Butters, N.12
Alford, M.13
-
7
-
-
84858610160
-
Wenning GK. Premotor signs and symptoms of multiple system atrophy
-
Jecmenica-Lukic M, Poewe W, Tolosa E. Wenning GK. Premotor signs and symptoms of multiple system atrophy. Lancet Neurol. 11(4), 361-368 (2012).
-
(2012)
Lancet Neurol.
, vol.11
, Issue.4
, pp. 361-368
-
-
Jecmenica-Lukic, M.1
Poewe, W.2
Tolosa, E.3
-
8
-
-
79952795522
-
Alpha-synuclein in Parkinson disease and other neurodegenerative disorders
-
Eller M, Williams DR. Alpha-synuclein in Parkinson disease and other neurodegenerative disorders. Clin. Chem. Lab. Med. 49(3), 403-408 (2011).
-
(2011)
Clin. Chem. Lab. Med.
, vol.49
, Issue.3
, pp. 403-408
-
-
Eller, M.1
Williams, D.R.2
-
9
-
-
0033919992
-
Lewy bodies in Alzheimer's Disease: A neuropathological review of 145 cases using α-synuclein immunohistochemistry
-
Hamilton RL. Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry. Brain Pathol. 10(3), 378-384 (2000). (Pubitemid 30431290)
-
(2000)
Brain Pathology
, vol.10
, Issue.3
, pp. 378-384
-
-
Hamilton, R.L.1
-
10
-
-
0032887585
-
Multiple system atrophy: A sporadic synucleinopathy
-
Dickson DW, Lin W, Liu WK, Yen SH. Multiple system atrophy: a sporadic synucleinopathy. Brain Pathol. 9(4), 721-732 (1999). (Pubitemid 29470964)
-
(1999)
Brain Pathology
, vol.9
, Issue.4
, pp. 721-732
-
-
Dickson, D.W.1
Lin, W.-L.2
Liu, W.-K.3
Yen, S.-H.4
-
11
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature 388(6645), 839-840 (1997).
-
(1997)
Nature
, vol.388
, Issue.6645
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
12
-
-
77953022918
-
Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease
-
Del Tredici K, Hawkes CH, Ghebremedhin E, Braak H. Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease. Acta NeuroPathol. 119(6), 703-713 (2010).
-
(2010)
Acta NeuroPathol.
, vol.119
, Issue.6
, pp. 703-713
-
-
Del Tredici, K.1
Hawkes, C.H.2
Ghebremedhin, E.3
Braak, H.4
-
13
-
-
84874210403
-
Enteric alpha-synuclein expression is increased in Parkinson's disease but not Alzheimer's disease
-
Gold A, Turkalp ZT, Munoz DG. Enteric alpha-synuclein expression is increased in Parkinson's disease but not Alzheimer's disease. Mov. Disord. 28(2), 237-240 (2013).
-
(2013)
Mov. Disord.
, vol.28
, Issue.2
, pp. 237-240
-
-
Gold, A.1
Turkalp, Z.T.2
Munoz, D.G.3
-
14
-
-
84880850040
-
Neuropsychiatric symptoms in patients with dementias associated with cortical Lewy bodies: Pathophysiology, clinical features pharmacological management
-
Ballard C, Aarsland D, Francis P, Corbett A. Neuropsychiatric symptoms in patients with dementias associated with cortical Lewy bodies: pathophysiology, clinical features pharmacological management. Drugs Aging 30(8), 603-611 (2013).
-
(2013)
Drugs Aging
, vol.30
, Issue.8
, pp. 603-611
-
-
Ballard, C.1
Aarsland, D.2
Francis, P.3
Corbett, A.4
-
15
-
-
0035815664
-
Evidence for a Partially Folded Intermediate in α-Synuclein Fibril Formation
-
DOI 10.1074/jbc.M010907200
-
Uversky VN, Li J, Fink AL. Evidence for a partially folded intermediate in alpha-synuclein fibril formation. J. Biol. Chem. 276(14), 10737-10744 (2001). (Pubitemid 38089246)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.14
, pp. 10737-10744
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
16
-
-
33750117120
-
Detection of novel intracellular α-synuclein oligomeric species by fluorescence lifetime imaging
-
DOI 10.1096/fj.05-5422com
-
Klucken J, Outeiro TF, Nguyen P, McLean PJ, Hyman BT. Detection of novel intracellular alpha-synuclein oligomeric species by fluorescence lifetime imaging FASEB J. 20(12), 2050-2057 (2006). (Pubitemid 44953904)
-
(2006)
FASEB Journal
, vol.20
, Issue.12
, pp. 2050-2057
-
-
Klucken, J.1
Outeiro, T.F.2
Nguyen, P.3
McLean, P.J.4
Hyman, B.T.5
-
17
-
-
0034827449
-
Cortical Lewy body pathology in the diagnosis of dementia
-
Harding AJ and Halliday GM. Cortical Lewy body pathology in the diagnosis of dementia. Acta NeuroPathol. 102(4), 355-363 (2001). (Pubitemid 32894706)
-
(2001)
Acta Neuropathologica
, vol.102
, Issue.4
, pp. 355-363
-
-
Harding, A.J.1
Halliday, G.M.2
-
18
-
-
1042266326
-
Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective
-
DOI 10.1074/jbc.M310994200
-
Tanaka M, Kim YM, Lee G, Junn E, Iwatsubo T, Mouradian MM. Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J. Biol. Chem. 279(6), 4625-4631 (2004). (Pubitemid 38199054)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4625-4631
-
-
Tanaka, M.1
Kim, Y.M.2
Lee, G.3
Junn, E.4
Iwatsubo, T.5
Mouradian, M.M.6
-
19
-
-
33846997878
-
Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies
-
Kramer ML and Schulz-Schaeffer WJ. Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies. J. Neurosci. 27(6), 1405-1410 (2007).
-
(2007)
J. Neurosci.
, vol.27
, Issue.6
, pp. 1405-1410
-
-
Kramer, M.L.1
Schulz-Schaeffer, W.J.2
-
20
-
-
34548172773
-
Different species of α-synuclein oligomers induce calcium influx and seeding
-
DOI 10.1523/JNEUROSCI.2617-07.2007
-
Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A et al. Different species of alpha-synuclein oligomers induce calcium influx and seeding. J. Neurosci. 27(34), 9220-9232 (2007). (Pubitemid 47312071)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.34
, pp. 9220-9232
-
-
Danzer, K.M.1
Haasen, D.2
Karow, A.R.3
Moussaud, S.4
Habeck, M.5
Giese, A.6
Kretzschmar, H.7
Hengerer, B.8
Kostka, M.9
-
21
-
-
44849125207
-
Formation of toxic oligomeric alpha-synuclein species in living cells
-
Outeiro TF, Putcha P, Tetzlaff JE et al. Formation of toxic oligomeric alpha-synuclein species in living cells. PLoS ONE 3(4), e1867 (2008).
-
(2008)
PLoS ONE
, vol.3
, Issue.4
-
-
Outeiro, T.F.1
Putcha, P.2
Tetzlaff, J.E.3
-
22
-
-
51449099473
-
Synuclein activates microglia in a model of Parkinson's disease
-
Su X, Maguire-Zeiss KA, Giuliano R, Prifti L, Venkatesh K, Federoff HJ. Synuclein activates microglia in a model of Parkinson's disease. Neurobiol. Aging 29(11), 1690-1701 (2008).
-
(2008)
Neurobiol. Aging
, vol.29
, Issue.11
, pp. 1690-1701
-
-
Su, X.1
Maguire-Zeiss, K.A.2
Giuliano, R.3
Prifti, L.4
Venkatesh, K.5
Federoff, H.J.6
-
23
-
-
70350338222
-
Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models
-
Karpinar DP, Balija MB, Kugler S et al. Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models. EMBO J. 28(20), 3256-3268 (2009).
-
(2009)
EMBO J.
, vol.28
, Issue.20
, pp. 3256-3268
-
-
Karpinar, D.P.1
Balija, M.B.2
Kugler, S.3
-
24
-
-
84885461450
-
Alpha-synucleinopathy associated with G51D SNCA mutation: A link between Parkinson's disease and multiple system atrophy?
-
Kiely AP, Asi YT, Kara E et al. Alpha-synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta NeuroPathol. 125(5), 753-769 (2013).
-
(2013)
Acta NeuroPathol.
, vol.125
, Issue.5
, pp. 753-769
-
-
Kiely, A.P.1
Asi, Y.T.2
Kara, E.3
-
26
-
-
63149090431
-
Parkinson's disease: From monogenic forms to genetic susceptibility factors
-
Lesage S, Brice A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet. 18(R1), R48-R59 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18 R1
-
-
Lesage, S.1
Brice, A.2
-
27
-
-
10744227740
-
Comparison of Kindreds with Parkinsonism and α-Synuclein Genomic Multiplications
-
DOI 10.1002/ana.10846
-
Farrer M, Kachergus J, Forno L et al. Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications. Ann. Neurol. 55(2), 174-179 (2004). (Pubitemid 38166993)
-
(2004)
Annals of Neurology
, vol.55
, Issue.2
, pp. 174-179
-
-
Farrer, M.1
Kachergus, J.2
Forno, L.3
Lincoln, S.4
Wang, D.-S.5
Hulihan, M.6
Maraganore, D.7
Gwinn-Hardy, K.8
Wszolek, Z.9
Dickson, D.10
Langston, J.W.11
-
28
-
-
4644290985
-
α-synuclein locus duplication as a cause of familial Parkinson's disease
-
DOI 10.1016/S0140-6736(04)17103-1, PII S0140673604171031
-
Chartier-Harlin MC, Kachergus J, Roumier C et al. Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364(9440), 1167-1169 (2004). (Pubitemid 39296604)
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1167-1169
-
-
Chartier-Harlin, M.-C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
Lincoln, S.6
Levecque, C.7
Larvor, L.8
Andrieux, J.9
Hulihan, M.10
Waucquier, N.11
Defebvre, L.12
Amouyel, P.13
Farrer, M.14
Destee, A.15
-
29
-
-
4644236043
-
Causal relation between α-synuclein gene duplication and familial Parkinson's disease
-
DOI 10.1016/S0140-6736(04)17104-3, PII S0140673604171043
-
Ibanez P, Bonnet AM, Debarges B et al. Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. Lancet 364(9440), 1169-1171 (2004). (Pubitemid 39296605)
-
(2004)
Lancet
, vol.364
, Issue.9440
, pp. 1169-1171
-
-
Ibanez, P.1
Bonnet, A.-M.2
Debarges, B.3
Lohmann, E.4
Tison, F.5
Pollak, P.6
Agid, Y.7
Durr, A.8
Brice, P.A.9
-
30
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
-
DOI 10.1073/pnas.97.2.571
-
Conway KA, Lee SJ, Rochet JC, Ding TT, Williamson RE, Lansbury PT Jr. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc. Natl Acad. Sci. USA 97(2), 571-576 (2000). (Pubitemid 30070350)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.2
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.-J.2
Rochet, J.-C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury Jr., P.T.6
-
31
-
-
0037456578
-
The formation of highly soluble oligomers of α-synuclein is regulated by fatty acids and enhanced in Parkinson's disease
-
DOI 10.1016/S0896-6273(03)00024-2
-
Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ. The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron 37(4), 583-595 (2003). (Pubitemid 36262981)
-
(2003)
Neuron
, vol.37
, Issue.4
, pp. 583-595
-
-
Sharon, R.1
Bar-Joseph, I.2
Frosch, M.P.3
Walsh, D.M.4
Hamilton, J.A.5
Selkoe, D.J.6
-
32
-
-
65249162241
-
Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
-
Paleologou KE, Kragh CL, Mann DM et al. Detection of elevated levels of soluble alpha-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies. Brain 132(Pt 4), 1093-1101 (2009).
-
(2009)
Brain
, vol.132
, Issue.PART. 4
, pp. 1093-1101
-
-
Paleologou, K.E.1
Kragh, C.L.2
Mann, D.M.3
-
33
-
-
33748325848
-
Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease
-
DOI 10.1016/j.bbrc.2006.08.024, PII S0006291X06018031
-
Tokuda T, Salem SA, Allsop D et al. Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease. Biochem. Biophys. Res. Commun. 349(1), 162-166 (2006). (Pubitemid 44331776)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.349
, Issue.1
, pp. 162-166
-
-
Tokuda, T.1
Salem, S.A.2
Allsop, D.3
Mizuno, T.4
Nakagawa, M.5
Qureshi, M.M.6
Locascio, J.J.7
Schlossmacher, M.G.8
El-Agnaf, O.M.A.9
-
34
-
-
84863230467
-
Endoplasmic reticulum stress is important for the manifestations of alpha-synucleinopathy in vivo
-
Colla E, Coune P, Liu Y, Pletnikova O, Troncoso JC, Iwatsubo T et al. Endoplasmic reticulum stress is important for the manifestations of alpha-synucleinopathy in vivo. J. Neurosci. 32(10), 3306-3320 (2012).
-
(2012)
J. Neurosci.
, vol.32
, Issue.10
, pp. 3306-3320
-
-
Colla, E.1
Coune, P.2
Liu, Y.3
Pletnikova, O.4
Troncoso, J.C.5
Iwatsubo, T.6
-
35
-
-
20144389524
-
Aggregated α-synuclein activates microglia: A process leading to disease progression in Parkinson's disease
-
DOI 10.1096/fj.04-2751com
-
Zhang W, Wang T, Pei Z et al. Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J. 19(6), 533-542 (2005). (Pubitemid 40471244)
-
(2005)
FASEB Journal
, vol.19
, Issue.6
, pp. 533-542
-
-
Zhang, W.1
Wang, T.2
Pei, Z.3
Miller, D.S.4
Wu, X.5
Block, M.L.6
Wilson, B.7
Zhang, W.8
Zhou, Y.9
Hong, J.-S.10
Zhang, J.11
-
36
-
-
76349097346
-
Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils
-
Wilms H, Rosenstiel P, Romero-Ramos M et al. Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils. Int. J. Immunopathol. Pharmacol. 22(4), 897-909 (2009).
-
(2009)
Int. J. Immunopathol. Pharmacol.
, vol.22
, Issue.4
, pp. 897-909
-
-
Wilms, H.1
Rosenstiel, P.2
Romero-Ramos, M.3
-
37
-
-
84865202477
-
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation
-
Diogenes MJ, Dias RB, Rombo DM et al. Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation. J. Neurosci. 32(34), 11750-11762 (2012).
-
(2012)
J. Neurosci.
, vol.32
, Issue.34
, pp. 11750-11762
-
-
Diogenes, M.J.1
Dias, R.B.2
Rombo, D.M.3
-
38
-
-
84865860748
-
Protein degradation pathways in Parkinson's disease: Curse or blessing
-
Ebrahimi-Fakhari D, Wahlster L, McLean PJ. Protein degradation pathways in Parkinson's disease: curse or blessing. Acta Neuropathol. 124(2), 153-172 (2012).
-
(2012)
Acta Neuropathol.
, vol.124
, Issue.2
, pp. 153-172
-
-
Ebrahimi-Fakhari, D.1
Wahlster, L.2
McLean, P.J.3
-
40
-
-
77953654063
-
Therapeutic antibodies in ophthalmology: Old is new again
-
Magdelaine-Beuzelin C, Pinault C, Paintaud G, Watier H. Therapeutic antibodies in ophthalmology: old is new again. MAbs 2(2), 176-180 (2011).
-
(2011)
Mabs
, vol.2
, Issue.2
, pp. 176-180
-
-
Magdelaine-Beuzelin, C.1
Pinault, C.2
Paintaud, G.3
Watier, H.4
-
41
-
-
84878467635
-
Established and forthcoming drugs for the treatment of osteoporosis
-
Lems WF, den Heijer M. Established and forthcoming drugs for the treatment of osteoporosis. Neth. J. Med. 71(4), 188-193 (2013).
-
(2013)
Neth. J. Med.
, vol.71
, Issue.4
, pp. 188-193
-
-
Lems, W.F.1
Den Heijer, M.2
-
43
-
-
84874041029
-
Natalizumab: Bench to bedside and beyond
-
Rudick R, Polman C, Clifford D, Miller D Steinman L. Natalizumab: bench to bedside and beyond. JAMA Neurol. 70(2), 172-182 (2013).
-
(2013)
JAMA Neurol.
, vol.70
, Issue.2
, pp. 172-182
-
-
Rudick, R.1
Polman, C.2
Clifford, D.3
Miller Steinman D, L.4
-
44
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
Schenk D, Barbour R, Dunn W et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400(6740), 173-177 (1999). (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
45
-
-
20944448555
-
Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial
-
DOI 10.1212/01.WNL.0000159740.16984.3C
-
Gilman S, Koller M, Black RS et al. Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial. Neurology 64(9), 1553-1562 (2005). (Pubitemid 40617691)
-
(2005)
Neurology
, vol.64
, Issue.9
, pp. 1553-1562
-
-
Gilman, S.1
Koller, M.2
Black, R.S.3
Jenkins, L.4
Griffith, S.G.5
Fox, N.C.6
Eisner, L.7
Kirby, L.8
Boada Rovira, M.9
Forette, F.10
Orgogozo, J.-M.11
-
46
-
-
1042265187
-
Neuropathology and Pathogenesis of Encephalitis Following Amyloid-β Immunization in Alzheimer's Disease
-
Ferrer I, Boada Rovira M, Sanchez Guerra ML, Rey MJ, Costa-Jussa F. Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease. Brain Pathol. 14(1), 11-20 (2004). (Pubitemid 38200585)
-
(2004)
Brain Pathology
, vol.14
, Issue.1
, pp. 11-20
-
-
Ferrer, I.1
Boada Rovira, M.2
Sanchez Guerra, M.L.3
Rey, M.J.4
Costa-Jussa, F.5
-
47
-
-
67049101507
-
Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial
-
Kokjohn TA, Roher AE. Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial. CNS Neurol. Disord. Drug Targets 8(2), 88-97 (2009).
-
(2009)
CNS Neurol. Disord. Drug Targets
, vol.8
, Issue.2
, pp. 88-97
-
-
Kokjohn, T.A.1
Roher, A.E.2
-
48
-
-
64549152492
-
Long-term follow-up of patients immunized with AN1792: Reduced functional decline in antibody responders
-
Vellas B, Black R, Thal LJ et al. Long-term follow-up of patients immunized with AN1792: reduced functional decline in antibody responders. Curr. Alzheimer Res. 6(2), 144-151 (2009).
-
(2009)
Curr. Alzheimer Res.
, vol.6
, Issue.2
, pp. 144-151
-
-
Vellas, B.1
Black, R.2
Thal, L.J.3
-
49
-
-
0036703483
-
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
-
Kotilinek LA, Bacskai B, Westerman M et al. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. J. Neurosci. 22(15), 6331-6335 (2002). (Pubitemid 35386387)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.15
, pp. 6331-6335
-
-
Kotilinek, L.A.1
Bacskai, B.2
Westerman, M.3
Kawarabayashi, T.4
Younkin, L.5
Hyman, B.T.6
Younkin, S.7
Ashe, K.H.8
-
50
-
-
0033835996
-
Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
DOI 10.1038/78682
-
Bard F, Cannon C, Barbour R et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat. Med. 6(8), 916-919 (2000). (Pubitemid 30644751)
-
(2000)
Nature Medicine
, vol.6
, Issue.8
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.-L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
51
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
-
DOI 10.1038/nn842
-
Dodart JC, Bales KR, Gannon KS et al. Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model. Nat. Neurosci. 5(5), 452-457 (2002). (Pubitemid 34454251)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.5
, pp. 452-457
-
-
Dodart, J.-C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
DeLong, C.A.7
Wu, S.8
Wu, X.9
Holtzman, D.M.10
Paul, S.M.11
-
52
-
-
9244231314
-
Assessment of the bioactivity of antibodies against β-amyloid peptide in vitro and in vivo
-
DOI 10.1159/000080981
-
Mohajeri MH, Gaugler MN, Martinez J et al. Assessment of the bioactivity of antibodies against beta-amyloid peptide in vitro and in vivo. Neurodegener. Dis. 1(4-5), 160-167 (2004). (Pubitemid 39551792)
-
(2004)
Neurodegenerative Diseases
, vol.1
, Issue.4-5
, pp. 160-167
-
-
Mohajeri, M.H.1
Gaugler, M.N.M.2
Martinez, J.3
Tracy, J.4
Li, H.5
Crameri, A.6
Kuehnle, K.7
Wollmer, M.A.8
Nitsch, R.M.9
-
53
-
-
73349091534
-
A Phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
-
Salloway S, Sperling R, Gilman S, Fox NC et al. A Phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 73(24), 2061-2070 (2009).
-
(2009)
Neurology
, vol.73
, Issue.24
, pp. 2061-2070
-
-
Salloway, S.1
Sperling, R.2
Gilman, S.3
Fox, N.C.4
-
54
-
-
77951086901
-
Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease
-
Siemers ER, Friedrich S, Dean RA et al. Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease. Clin. Neuropharmacol. 33(2), 67-73 (2010).
-
(2010)
Clin. Neuropharmacol.
, vol.33
, Issue.2
, pp. 67-73
-
-
Siemers, E.R.1
Friedrich, S.2
Dean, R.A.3
-
55
-
-
70350324013
-
An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease
-
Lord A, Gumucio A, Englund H et al. An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease. Neurobiol. Dis. 36(3), 425-434 (2009).
-
(2009)
Neurobiol. Dis.
, vol.36
, Issue.3
, pp. 425-434
-
-
Lord, A.1
Gumucio, A.2
Englund, H.3
-
56
-
-
79953297689
-
Heavy-chain complementarity-determining regions determine conformation selectivity of anti-abeta antibodies
-
Sehlin D, Hedlund M, Lord A et al. Heavy-chain complementarity- determining regions determine conformation selectivity of anti-abeta antibodies. Neurodegener. Dis. 8(3), 117-123 (2011).
-
(2011)
Neurodegener. Dis.
, vol.8
, Issue.3
, pp. 117-123
-
-
Sehlin, D.1
Hedlund, M.2
Lord, A.3
-
57
-
-
20444413356
-
Effects of α-synuclein immunization in a mouse model of Parkinson's disease
-
DOI 10.1016/j.neuron.2005.05.010, PII S0896627305004058
-
Masliah E, Rockenstein E, Adame A et al. Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron 46(6), 857-868 (2005). (Pubitemid 40805347)
-
(2005)
Neuron
, vol.46
, Issue.6
, pp. 857-868
-
-
Masliah, E.1
Rockenstein, E.2
Adame, A.3
Alford, M.4
Crews, L.5
Hashimoto, M.6
Seubert, P.7
Lee, M.8
Goldstein, J.9
Chilcote, T.10
Games, D.11
Schenk, D.12
-
58
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
DOI 10.1126/science.287.5456.1265
-
Masliah E, Rockenstein E, Veinbergs I et al. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 287(5456), 1265-1269 (2000). (Pubitemid 30112148)
-
(2000)
Science
, vol.287
, Issue.5456
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
59
-
-
84879934105
-
Alpha-synuclein vaccination prevents the accumulation of Parkinson disease-like pathologic inclusions in striatum in association with regulatory T cell recruitment in a rat model
-
Sanchez-Guajardo V, Annibali A, Jensen PH, Romero-Ramos M. Alpha-synuclein vaccination prevents the accumulation of Parkinson disease-like pathologic inclusions in striatum in association with regulatory T cell recruitment in a rat model. J. Neuropathol. Exp. Neurol. 72(7), 624-645 (2013).
-
(2013)
J. Neuropathol. Exp. Neurol.
, vol.72
, Issue.7
, pp. 624-645
-
-
Sanchez-Guajardo, V.1
Annibali, A.2
Jensen, P.H.3
Romero-Ramos, M.4
-
60
-
-
84858685308
-
Vaccination for Parkinson's disease
-
Schneeberger A, Mandler M, Mattner F, Schmidt W. Vaccination for Parkinson's disease. Parkinsonism Relat. Disord. 18(Suppl. 1), S11-S13 (2012).
-
(2012)
Parkinsonism Relat. Disord.
, vol.18
, Issue.SUPPL. 1
-
-
Schneeberger, A.1
Mandler, M.2
Mattner, F.3
Schmidt, W.4
-
61
-
-
79955757052
-
Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease
-
Masliah E, Rockenstein E, Mante M et al. Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease. PLoS ONE 6(4), e19338 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Masliah, E.1
Rockenstein, E.2
Mante, M.3
-
62
-
-
34250832784
-
Calpain-cleavage of α-synuclein: Connecting proteolytic processing to disease-linked aggregation
-
DOI 10.2353/ajpath.2007.061232
-
Dufty BM, Warner LR, Hou ST et al. Calpain-cleavage of alpha-synuclein: connecting proteolytic processing to disease-linked aggregation. Am J. Pathol. 170(5), 1725-1738 (2007). (Pubitemid 47339316)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1725-1738
-
-
Dufty, B.M.1
Warner, L.R.2
Hou, S.T.3
Jiang, S.X.4
Gomez-Isla, T.5
Leenhouts, K.M.6
Oxford, J.T.7
Feany, M.B.8
Masliah, E.9
Rohn, T.T.10
-
63
-
-
80052529044
-
Beta-glucocerebrosidase gene mutations in two cohorts of Greek patients with sporadic Parkinson's disease
-
Moraitou M, Hadjigeorgiou G, Monopolis I et al. Beta-glucocerebrosidase gene mutations in two cohorts of Greek patients with sporadic Parkinson's disease. Mol. Genet. Metab. 104(1-2), 149-152 (2011).
-
(2011)
Mol. Genet. Metab.
, vol.104
, Issue.1-2
, pp. 149-152
-
-
Moraitou, M.1
Hadjigeorgiou, G.2
Monopolis, I.3
-
64
-
-
33645833848
-
Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
-
DOI 10.1096/fj.03-1449com
-
El-Agnaf OM, Salem SA, Paleologou KE et al. Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson's disease. FASEB J. 20(3), 419-425 (2006). (Pubitemid 44933318)
-
(2006)
FASEB Journal
, vol.20
, Issue.3
, pp. 419-425
-
-
El-Agnaf, O.M.A.1
Salem, S.A.2
Paleologou, K.E.3
Curran, M.D.4
Gibson, M.J.5
Court, J.A.6
Schlossmacher, M.G.7
Allsop, D.8
-
65
-
-
85109083933
-
Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
-
El-Agnaf OM, Salem SA, Paleologou KE et al. Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma. FASEB J. 17(13), 1945-1947 (2003).
-
(2003)
FASEB J.
, vol.17
, Issue.13
, pp. 1945-1947
-
-
El-Agnaf, O.M.1
Salem, S.A.2
Paleologou, K.E.3
-
66
-
-
82655171636
-
Phosphorylated alpha-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease
-
Foulds PG, Mitchell JD, Parker A et al. Phosphorylated alpha-synuclein can be detected in blood plasma and is potentially a useful biomarker for Parkinson's disease. FASEB J. 25(12), 4127-4137 (2011).
-
(2011)
FASEB J.
, vol.25
, Issue.12
, pp. 4127-4137
-
-
Foulds, P.G.1
Mitchell, J.D.2
Parker, A.3
-
67
-
-
69149089854
-
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
-
Desplats P, Lee HJ, Bae EJ et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc. Natl Acad. Sci. USA 106(31), 13010-13015 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.31
, pp. 13010-13015
-
-
Desplats, P.1
Lee, H.J.2
Bae, E.J.3
-
68
-
-
79551519276
-
Alpha-synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
-
Hansen C, Angot E, Bergstrom AL et al. Alpha-synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells. J. Clin. Invest. 121(2), 715-725 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, Issue.2
, pp. 715-725
-
-
Hansen, C.1
Angot, E.2
Bergstrom, A.L.3
-
69
-
-
77950571596
-
Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies
-
Lee HJ, Suk JE, Patrick C et al. Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies. J. Biol. Chem. 285(12), 9262-9272 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.12
, pp. 9262-9272
-
-
Lee, H.J.1
Suk, J.E.2
Patrick, C.3
-
70
-
-
84865307818
-
Exosomal cell-to-cell transmission of alpha synuclein oligomers
-
Danzer KM, Kranich LR, Ruf WP et al. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol. Neurodegener. 7, 42 (2012).
-
(2012)
Mol. Neurodegener.
, vol.7
, Issue.42
-
-
Danzer, K.M.1
Kranich, L.R.2
Ruf, W.P.3
-
71
-
-
77951885732
-
Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions
-
Jang A, Lee HJ, Suk JE, Jung JW, Kim KP, Lee SJ. Non-classical exocytosis of alpha-synuclein is sensitive to folding states and promoted under stress conditions. J. Neurochem. 113(5), 1263-1274 (2010).
-
(2010)
J. Neurochem.
, vol.113
, Issue.5
, pp. 1263-1274
-
-
Jang, A.1
Lee, H.J.2
Suk, J.E.3
Jung, J.W.4
Kim, K.P.5
Lee, S.J.6
-
72
-
-
61849178720
-
Prions hijack tunnelling nanotubes for intercellular spread
-
Gousset K, Schiff E, Langevin C et al. Prions hijack tunnelling nanotubes for intercellular spread. Nat. Cell Biol. 11(3), 328-336 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.3
, pp. 328-336
-
-
Gousset, K.1
Schiff, E.2
Langevin, C.3
-
73
-
-
79960308070
-
Assessment of alpha-synuclein secretion in mouse and human brain parenchyma
-
Emmanouilidou E, Elenis D, Papasilekas T et al. Assessment of alpha-synuclein secretion in mouse and human brain parenchyma. PLoS ONE 6(7), e22225 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.7
-
-
Emmanouilidou, E.1
Elenis, D.2
Papasilekas, T.3
-
74
-
-
84866679781
-
Antibody-aided clearance of extracellular alpha-synuclein prevents cell-to-cell aggregate transmission
-
Bae EJ, Lee HJ, Rockenstein E et al. Antibody-aided clearance of extracellular alpha-synuclein prevents cell-to-cell aggregate transmission. J. Neurosci. 32(39), 13454-13469 (2012).
-
(2012)
J. Neurosci.
, vol.32
, Issue.39
, pp. 13454-13469
-
-
Bae, E.J.1
Lee, H.J.2
Rockenstein, E.3
-
75
-
-
0036953160
-
Passage of amyloid β protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease
-
DOI 10.1016/S0196-9781(02)00261-9, PII S0196978102002619
-
Banks WA, Terrell B, Farr SA, Robinson SM, Nonaka N, Morley JE. Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease. Peptides 23(12), 2223-2226 (2002). (Pubitemid 36092057)
-
(2002)
Peptides
, vol.23
, Issue.12
, pp. 2223-2226
-
-
Banks, W.A.1
Terrell, B.2
Farr, S.A.3
Robinson, S.M.4
Nonaka, N.5
Morley, J.E.6
-
76
-
-
84879968745
-
Developing therapeutic antibodies for neurodegenerative disease
-
Yu YJ, Watts RJ. Developing therapeutic antibodies for neurodegenerative disease. Neurotherapeutics 10(3), 459-472 (2013).
-
(2013)
Neurotherapeutics
, vol.10
, Issue.3
, pp. 459-472
-
-
Yu, Y.J.1
Watts, R.J.2
-
77
-
-
34147130637
-
Isolation of a Human Single Chain Antibody Fragment Against Oligomeric α-Synuclein that Inhibits Aggregation and Prevents α-Synuclein- induced Toxicity
-
DOI 10.1016/j.jmb.2007.02.089, PII S0022283607003075
-
Emadi S, Barkhordarian H, Wang MS, Schulz P, Sierks MR. Isolation of a human single chain antibody fragment against oligomeric alpha-synuclein that inhibits aggregation and prevents alpha-synuclein-induced toxicity. J. Mol Biol. 368(4), 1132-1144 (2007). (Pubitemid 46574670)
-
(2007)
Journal of Molecular Biology
, vol.368
, Issue.4
, pp. 1132-1144
-
-
Emadi, S.1
Barkhordarian, H.2
Wang, M.S.3
Schulz, P.4
Sierks, M.R.5
-
78
-
-
84879419913
-
Monoclonal antibodies selective for alpha-synuclein oligomers/ protofibrils recognize brain pathology in Lewy body disorders and transgenic mice expressing the disease-causing A30P mutation
-
Fagerqvist T, Lindstrom V, Nordstrom E et al. Monoclonal antibodies selective for alpha-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and transgenic mice expressing the disease-causing A30P mutation. J. Neurochem. 126(1), 131-144 (2013).
-
(2013)
J. Neurochem.
, vol.126
, Issue.1
, pp. 131-144
-
-
Fagerqvist, T.1
Lindstrom, V.2
Nordstrom, E.3
-
79
-
-
80055113204
-
Antibodies against alpha-synuclein reduce oligomerization in living cells
-
Nasstrom T, Goncalves S, Sahlin C et al. Antibodies against alpha-synuclein reduce oligomerization in living cells. PLoS ONE 6(10), e27230 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.10
-
-
Nasstrom, T.1
Goncalves, S.2
Sahlin, C.3
-
80
-
-
34447570901
-
Age-dependent cognitive decline and amygdala pathology in α-synuclein transgenic mice
-
DOI 10.1016/j.neurobiolaging.2006.06.013, PII S0197458006002235
-
Freichel C, Neumann M, Ballard T et al. Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice. Neurobiol. Aging 28(9), 1421-1435 (2007). (Pubitemid 47081234)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.9
, pp. 1421-1435
-
-
Freichel, C.1
Neumann, M.2
Ballard, T.3
Muller, V.4
Woolley, M.5
Ozmen, L.6
Borroni, E.7
Kretzschmar, H.A.8
Haass, C.9
Spooren, W.10
Kahle, P.J.11
-
81
-
-
10344257196
-
A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed α-synuclein
-
DOI 10.1016/j.ymthe.2004.08.019, PII S1525001604014157
-
Zhou C, Emadi S, Sierks MR, Messer A. A human single-chain Fv intrabody blocks aberrant cellular effects of overexpressed alpha-synuclein. Mol. Ther. 10(6), 1023-1031 (2004). (Pubitemid 39625246)
-
(2004)
Molecular Therapy
, vol.10
, Issue.6
, pp. 1023-1031
-
-
Zhou, C.1
Emadi, S.2
Sierks, M.R.3
Messer, A.4
-
82
-
-
39649109675
-
An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity
-
Lynch SM, Zhou C, Messer A. An scFv intrabody against the nonamyloid component of alpha-synuclein reduces intracellular aggregation and toxicity. J. Mol. Biol. 377(1), 136-147 (2008).
-
(2008)
J. Mol. Biol.
, vol.377
, Issue.1
, pp. 136-147
-
-
Lynch, S.M.1
Zhou, C.2
Messer, A.3
-
83
-
-
5644271409
-
Role of microglia in central nervous system infections
-
DOI 10.1128/CMR.17.4.942-964.2004
-
Rock RB, Gekker G, Hu S et al. Role of microglia in central nervous system infections. Clin. Microbiol. Rev. 17(4), table of contents 942-964 (2004). (Pubitemid 39372525)
-
(2004)
Clinical Microbiology Reviews
, vol.17
, Issue.4
, pp. 942-964
-
-
Rock, R.B.1
Gekker, G.2
Hu, S.3
Sheng, W.S.4
Cheeran, M.5
Lokensgard, J.R.6
Peterson, P.K.7
-
84
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity 32(5), 593-604 (2010).
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
85
-
-
33846794644
-
+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
DOI 10.1016/j.jneuroim.2006.11.009, PII S0165572806004760
-
Laurie C, Reynolds A, Coskun O, Bowman E, Gendelman HE, Mosley RL. CD4+ T cells from copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J. Neuroimmunol. 183(1-2), 60-68 (2007). (Pubitemid 46204910)
-
(2007)
Journal of Neuroimmunology
, vol.183
, Issue.1-2
, pp. 60-68
-
-
Laurie, C.1
Reynolds, A.2
Coskun, O.3
Bowman, E.4
Gendelman, H.E.5
Mosley, R.L.6
-
86
-
-
36249032567
-
Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease
-
DOI 10.1189/jlb.0507296
-
Reynolds AD, Banerjee R, Liu J, Gendelman HE, Mosley RL. Neuroprotective activities of CD4+CD25+ regulatory T cells in an animal model of Parkinson's disease. J. Leukoc. Biol. 82(5), 1083-1094 (2007). (Pubitemid 350133504)
-
(2007)
Journal of Leukocyte Biology
, vol.82
, Issue.5
, pp. 1083-1094
-
-
Reynolds, A.D.1
Banerjee, R.2
Liu, J.3
Gendelman, H.E.4
Mosley, R.L.5
-
87
-
-
77951882307
-
Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease
-
Reynolds AD, Stone DK, Hutter JA, Benner EJ, Mosley RL, Gendelman HE. Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease. J. Immunol. 184(5), 2261-2271 (2010).
-
(2010)
J. Immunol.
, vol.184
, Issue.5
, pp. 2261-2271
-
-
Reynolds, A.D.1
Stone, D.K.2
Hutter, J.A.3
Benner, E.J.4
Mosley, R.L.5
Gendelman, H.E.6
-
88
-
-
0035902619
-
Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease
-
DOI 10.1073/pnas.151261398
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc. Natl Acad. Sci. USA 98(15), 8850-8855 (2001). (Pubitemid 32678116)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.15
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.-C.4
Paul, S.M.5
Holtzman, D.M.6
-
89
-
-
84873641251
-
Naturally occurring alpha-synuclein autoantibody levels are lower in patients with Parkinson disease
-
Besong-Agbo D, Wolf E, Jessen F et al. Naturally occurring alpha-synuclein autoantibody levels are lower in patients with Parkinson disease. Neurology 80(2), 169-175 (2012).
-
(2012)
Neurology
, vol.80
, Issue.2
, pp. 169-175
-
-
Besong-Agbo, D.1
Wolf, E.2
Jessen, F.3
-
90
-
-
79953308255
-
Immunoprotection against toxic biomarkers is retained during Parkinson's disease progression
-
Gruden MA, Sewell RD, Yanamandra K et al. Immunoprotection against toxic biomarkers is retained during Parkinson's disease progression. J. Neuroimmunol. 233(1-2), 221-227 (2011).
-
(2011)
J. Neuroimmunol.
, vol.233
, Issue.1-2
, pp. 221-227
-
-
Gruden, M.A.1
Sewell, R.D.2
Yanamandra, K.3
-
91
-
-
79955554760
-
Alpha-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients
-
Yanamandra K, Gruden MA, Casaite V, Meskys R, Forsgren L, Morozova-Roche LA. Alpha-synuclein reactive antibodies as diagnostic biomarkers in blood sera of Parkinson's disease patients. PLoS ONE 6(4), e18513 (2011).
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Yanamandra, K.1
Gruden, M.A.2
Casaite, V.3
Meskys, R.4
Forsgren, L.5
Morozova-Roche, L.A.6
-
92
-
-
34247402084
-
Autoantibodies to alpha-synuclein in inherited Parkinson's disease
-
DOI 10.1111/j.1471-4159.2006.04365.x
-
Papachroni KK, Ninkina N, Papapanagiotou A et al. Autoantibodies to alpha-synuclein in inherited Parkinson's disease. J. Neurochem. 101(3), 749-756 (2007). (Pubitemid 46633311)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.3
, pp. 749-756
-
-
Papachroni, K.K.1
Ninkina, N.2
Papapanagiotou, A.3
Hadjigeorgiou, G.M.4
Xiromerisiou, G.5
Papadimitriou, A.6
Kalofoutis, A.7
Buchman, V.L.8
-
93
-
-
84871324721
-
Alpha-synuclein and anti-alpha-synuclein antibodies in Parkinson's disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls
-
Smith LM, Schiess MC, Coffey MP, Klaver AC Loeffler DA. Alpha-synuclein and anti-alpha-synuclein antibodies in Parkinson's disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls. PLoS ONE 7(12), e52285 (2012).
-
(2012)
PLoS ONE
, vol.7
, Issue.12
-
-
Smith, L.M.1
Schiess, M.C.2
Coffey, M.P.3
Klaver Loeffler, A.C.D.A.4
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