메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Oxidative stress and metabolic syndrome: Cause or consequence of Alzheimer's disease?

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; COMPLICATION; HUMAN; METABOLIC SYNDROME X; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PATHOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; VASCULAR ENDOTHELIUM;

EID: 84893834710     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/497802     Document Type: Review
Times cited : (127)

References (96)
  • 2
    • 77953675879 scopus 로고    scopus 로고
    • Probing the biology of Alzheimer's disease in mice
    • 2-s2.0-77953675879 10.1016/j.neuron.2010.04.031
    • Ashe K. H., Zahs K. R., Probing the biology of Alzheimer's disease in mice. Neuron 2010 66 5 631 645 2-s2.0-77953675879 10.1016/j.neuron.2010.04.031
    • (2010) Neuron , vol.66 , Issue.5 , pp. 631-645
    • Ashe, K.H.1    Zahs, K.R.2
  • 3
    • 84883578547 scopus 로고    scopus 로고
    • Beta-Amyloid oligomers in aging and Alzheimer's disease
    • Zahs K. R., Ashe K. H., beta-Amyloid oligomers in aging and Alzheimer's disease. Frontiers in Aging Neuroscience 2013 5 28
    • (2013) Frontiers in Aging Neuroscience , vol.5 , pp. 28
    • Zahs, K.R.1    Ashe, K.H.2
  • 4
    • 77749308402 scopus 로고    scopus 로고
    • Amyloid oligomers: Formation and toxicity of A β oligomers
    • 2-s2.0-77749308402 10.1111/j.1742-4658.2010.07568.x
    • Sakono M., Zako T., Amyloid oligomers: formation and toxicity of A β oligomers. The FEBS Journal 2010 277 6 1348 1358 2-s2.0-77749308402 10.1111/j.1742-4658.2010.07568.x
    • (2010) The FEBS Journal , vol.277 , Issue.6 , pp. 1348-1358
    • Sakono, M.1    Zako, T.2
  • 5
    • 2542427690 scopus 로고    scopus 로고
    • Oligomers in the brain: The emerging role of soluble protein aggregates in neurodegeneration
    • DOI 10.2174/0929866043407174
    • Walsh D. M., Selkoe D. J., Oligomers in the brain: the emerging role of soluble protein aggregates in neurodegeneration. Protein and Peptide Letters 2004 11 3 213 228 2-s2.0-2542427690 10.2174/0929866043407174 (Pubitemid 38689025)
    • (2004) Protein and Peptide Letters , vol.11 , Issue.3 , pp. 213-228
    • Walsh, D.M.1    Selkoe, D.J.2
  • 6
    • 58149385218 scopus 로고    scopus 로고
    • Picomolar amyloid- β positively modulates synaptic plasticity and memory in hippocampus
    • 2-s2.0-58149385218 10.1523/JNEUROSCI.2692-08.2008
    • Puzzo D., Privitera L., Leznik E., Fà M., Staniszewski A., Palmeri A., Arancio O., Picomolar amyloid- β positively modulates synaptic plasticity and memory in hippocampus. Journal of Neuroscience 2008 28 53 14537 14545 2-s2.0-58149385218 10.1523/JNEUROSCI.2692-08.2008
    • (2008) Journal of Neuroscience , vol.28 , Issue.53 , pp. 14537-14545
    • Puzzo, D.1    Privitera, L.2    Leznik, E.3    Fà, M.4    Staniszewski, A.5    Palmeri, A.6    Arancio, O.7
  • 7
    • 84861198956 scopus 로고    scopus 로고
    • Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory
    • 2-s2.0-84856070705 10.1016/j.neurobiolaging.2011.12.020
    • Puzzo D., Privitera L., Palmeri A., Hormetic effect of amyloid-beta peptide in synaptic plasticity and memory. Neurobiology of Aging 2012 33 7 e15 e24 2-s2.0-84856070705 10.1016/j.neurobiolaging.2011.12.020
    • (2012) Neurobiology of Aging , vol.33 , Issue.7
    • Puzzo, D.1    Privitera, L.2    Palmeri, A.3
  • 8
    • 80052027401 scopus 로고    scopus 로고
    • Alzheimer's disease: Synapses gone cold
    • 2-s2.0-80052027401 10.1186/1750-1326-6-63
    • Koffie R. M., Hyman B. T., Spires-Jones T. L., Alzheimer's disease: synapses gone cold. Molecular Neurodegeneration 2011 6 1 63 2-s2.0-80052027401 10.1186/1750-1326-6-63
    • (2011) Molecular Neurodegeneration , vol.6 , Issue.1 , pp. 63
    • Koffie, R.M.1    Hyman, B.T.2    Spires-Jones, T.L.3
  • 9
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta, mitochondrial dysfunction and synaptic damage: Implications for cognitive decline in aging and Alzheimer's disease
    • 2-s2.0-39149122810 10.1016/j.molmed.2007.12.002
    • Reddy P. H., Beal M. F., Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends in Molecular Medicine 2008 14 2 45 53 2-s2.0-39149122810 10.1016/j.molmed.2007.12.002
    • (2008) Trends in Molecular Medicine , vol.14 , Issue.2 , pp. 45-53
    • Reddy, P.H.1    Beal, M.F.2
  • 10
    • 12844266117 scopus 로고    scopus 로고
    • The critical role of methionine 35 in Alzheimer's amyloid β-peptide (1-42)-induced oxidative stress and neurotoxicity
    • DOI 10.1016/j.bbapap.2004.10.014, PII S1570963904002961, Mewthionine Oxidation and Methionine Sulfoxide Reductases
    • Butterfield D. A., Boyd-Kimball D., The critical role of methionine 35 in Alzheimer's amyloid β -peptide (1-42)-induced oxidative stress and neurotoxicity. Biochimica et Biophysica Acta 2005 1703 2 149 156 2-s2.0-12844266117 10.1016/j.bbapap.2004.10.014 (Pubitemid 40170438)
    • (2005) Biochimica et Biophysica Acta - Proteins and Proteomics , vol.1703 , Issue.2 , pp. 149-156
    • Butterfield, D.A.1    Boyd-Kimball, D.2
  • 11
    • 1842519391 scopus 로고    scopus 로고
    • Alzheimer's amyloid β-peptide (1-42): Involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide
    • DOI 10.1016/j.neurobiolaging.2003.12.027, PII S0197458004000880
    • Butterfield D. A., Bush A. I., Alzheimer's amyloid β -peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide. Neurobiology of Aging 2004 25 5 563 568 2-s2.0-1842519391 10.1016/j.neurobiolaging.2003.12.027 (Pubitemid 38686475)
    • (2004) Neurobiology of Aging , vol.25 , Issue.5 , pp. 563-568
    • Butterfield, D.A.1    Bush, A.I.2
  • 12
    • 0035997233 scopus 로고    scopus 로고
    • Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid β-peptide 1-42
    • DOI 10.1016/S0196-9781(02)00066-9, PII S0196978102000669
    • Butterfield D. A., Kanski J., Methionine residue 35 is critical for the oxidative stress and neurotoxic properties of Alzheimer's amyloid β -peptide 1-42. Peptides 2002 23 7 1299 1309 2-s2.0-0035997233 10.1016/S0196-9781(02)00066-9 (Pubitemid 34786708)
    • (2002) Peptides , vol.23 , Issue.7 , pp. 1299-1309
    • Butterfield, D.A.1    Kanski, J.2
  • 13
    • 0035194145 scopus 로고    scopus 로고
    • Evidence of oxidative damage in Alzheimer's disease brain: Central role for amyloid β-peptide
    • DOI 10.1016/S1471-4914(01)02173-6, PII S1471491401021736
    • Butterfield D. A., Drake J., Pocernich C., Castegna A., Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β -peptide. Trends in Molecular Medicine 2001 7 12 548 554 2-s2.0-0035194145 10.1016/S1471-4914(01)02173-6 (Pubitemid 33127140)
    • (2001) Trends in Molecular Medicine , vol.7 , Issue.12 , pp. 548-554
    • Butterfield, D.A.1    Drake, J.2    Pocernich, C.3    Castegna, A.4
  • 15
    • 0024745894 scopus 로고
    • Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
    • 2-s2.0-0024745894
    • Goedert M., Spillantini M. G., Jakes R., Rutherford D., Crowther R. A., Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989 3 4 519 526 2-s2.0-0024745894
    • (1989) Neuron , vol.3 , Issue.4 , pp. 519-526
    • Goedert, M.1    Spillantini, M.G.2    Jakes, R.3    Rutherford, D.4    Crowther, R.A.5
  • 16
    • 0028785525 scopus 로고
    • Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain
    • 2-s2.0-0028785525 10.1083/jcb.131.5.1327
    • Brandt R., Léger J., Lee G., Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain. Journal of Cell Biology 1995 131 5 1327 1340 2-s2.0-0028785525 10.1083/jcb.131.5.1327
    • (1995) Journal of Cell Biology , vol.131 , Issue.5 , pp. 1327-1340
    • Brandt, R.1    Léger, J.2    Lee, G.3
  • 17
    • 0031035402 scopus 로고    scopus 로고
    • Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly
    • Goode B. L., Denis P. E., Panda D., Radeke M. J., Miller H. P., Wilson L., Feinstein S. C., Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly. Molecular Biology of the Cell 1997 8 2 353 365 2-s2.0-0031035402 (Pubitemid 27097949)
    • (1997) Molecular Biology of the Cell , vol.8 , Issue.2 , pp. 353-365
    • Goode, B.L.1    Denis, P.E.2    Panda, D.3    Radeke, M.J.4    Miller, H.P.5    Wilson, L.6    Feinstein, S.C.7
  • 18
    • 21644446496 scopus 로고    scopus 로고
    • Sites of tau important for aggregation populate β-structure and bind to microtubules and polyanions
    • DOI 10.1074/jbc.M501565200
    • Mukrasch M. D., Biernat J., von Bergen M., Griesinger C., Mandelkow E., Zweckstetter M., Sites of tau important for aggregation populate β -structure and bind to microtubules and polyanions. Journal of Biological Chemistry 2005 280 26 24978 24986 2-s2.0-21644446496 10.1074/jbc.M501565200 (Pubitemid 40934590)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.26 , pp. 24978-24986
    • Mukrasch, M.D.1    Biernat, J.2    Von Bergen, M.3    Griesinger, C.4    Mandelkow, E.5    Zweckstetter, M.6
  • 19
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • 2-s2.0-0025863618
    • Braak H., Braak E., Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica 1991 82 4 239 259 2-s2.0-0025863618
    • (1991) Acta Neuropathologica , vol.82 , Issue.4 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 20
    • 84858965241 scopus 로고    scopus 로고
    • Identification of oligomers at early stages of tau aggregation in Alzheimer's disease
    • Lasagna-Reeves C. A., Castillo-Carranza D. L., Sengupta U., Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. The FASEB Journal 2012 26 5 1946 1959
    • (2012) The FASEB Journal , vol.26 , Issue.5 , pp. 1946-1959
    • Lasagna-Reeves, C.A.1    Castillo-Carranza, D.L.2    Sengupta, U.3
  • 22
    • 1342269756 scopus 로고    scopus 로고
    • Coupled reductions in brain oxidative phosphorylation and synaptic function can be quantified and staged in the course of Alzheimer disease
    • 2-s2.0-1342269756 10.1007/BF03033167
    • Rapoport S. I., Coupled reductions in brain oxidative phosphorylation and synaptic function can be quantified and staged in the course of Alzheimer disease. Neurotoxicity Research 2003 5 6 385 397 2-s2.0-1342269756 10.1007/BF03033167
    • (2003) Neurotoxicity Research , vol.5 , Issue.6 , pp. 385-397
    • Rapoport, S.I.1
  • 23
  • 24
    • 79952105548 scopus 로고    scopus 로고
    • Post-translational modifications of tau protein: Implications for Alzheimer's disease
    • 2-s2.0-79952105548 10.1016/j.neuint.2010.12.023
    • Martin L., Latypova X., Terro F., Post-translational modifications of tau protein: implications for Alzheimer's disease. Neurochemistry International 2011 58 4 458 471 2-s2.0-79952105548 10.1016/j.neuint.2010.12.023
    • (2011) Neurochemistry International , vol.58 , Issue.4 , pp. 458-471
    • Martin, L.1    Latypova, X.2    Terro, F.3
  • 25
    • 67650556426 scopus 로고    scopus 로고
    • Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: Implications for the pathogenesis of Alzheimer disease
    • 2-s2.0-67650556426 10.1074/jbc.M808908200
    • Quintanilla R. A., Matthews-Roberson T. A., Dolan P. J., Johnsion G. V. W., Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease. Journal of Biological Chemistry 2009 284 28 18754 18766 2-s2.0-67650556426 10.1074/jbc.M808908200
    • (2009) Journal of Biological Chemistry , vol.284 , Issue.28 , pp. 18754-18766
    • Quintanilla, R.A.1    Matthews-Roberson, T.A.2    Dolan, P.J.3    Johnsion, G.V.W.4
  • 27
    • 0141960033 scopus 로고    scopus 로고
    • β-amyloid induces paired helical filament-like tau filaments in tissue culture
    • DOI 10.1074/jbc.M308243200
    • Ferrari A., Hoerndli F., Baechi T., Nitsch R. M., Götz J., β -amyloid induces paired helical filament-like tau filaments in tissue culture. Journal of Biological Chemistry 2003 278 41 40162 40168 2-s2.0-0141960033 10.1074/jbc.M308243200 (Pubitemid 37248584)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.41 , pp. 40162-40168
    • Ferrari, A.1    Hoerndli, F.2    Baechi, T.3    Nitsch, R.M.4    Gotz, J.5
  • 28
    • 0026573467 scopus 로고
    • Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: A laser microprobe (LAMMA) study
    • 2-s2.0-0026573467
    • Good P. F., Perl D. P., Bierer L. M., Schmeidler J., Selective accumulation of aluminum and iron in the neurofibrillary tangles of Alzheimer's disease: a laser microprobe (LAMMA) study. Annals of Neurology 1992 31 3 286 292 2-s2.0-0026573467
    • (1992) Annals of Neurology , vol.31 , Issue.3 , pp. 286-292
    • Good, P.F.1    Perl, D.P.2    Bierer, L.M.3    Schmeidler, J.4
  • 30
    • 43849096294 scopus 로고    scopus 로고
    • Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease
    • 2-s2.0-43849096294 10.1016/j.freeradbiomed.2008.03.012
    • Resende R., Moreira P. I., Proença T., Deshpande A., Busciglio J., Pereira C., Oliveira C. R., Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free Radical Biology and Medicine 2008 44 12 2051 2057 2-s2.0-43849096294 10.1016/j.freeradbiomed.2008.03.012
    • (2008) Free Radical Biology and Medicine , vol.44 , Issue.12 , pp. 2051-2057
    • Resende, R.1    Moreira, P.I.2    Proença, T.3    Deshpande, A.4    Busciglio, J.5    Pereira, C.6    Oliveira, C.R.7
  • 31
    • 72249109630 scopus 로고    scopus 로고
    • Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells
    • 2-s2.0-72249109630 10.1016/j.neulet.2009.11.010
    • Su B., Wang X., Lee H.-G., Tabaton M., Perry G., Smith M. A., Zhu X., Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neuroscience Letters 2010 468 3 267 271 2-s2.0-72249109630 10.1016/j.neulet.2009.11.010
    • (2010) Neuroscience Letters , vol.468 , Issue.3 , pp. 267-271
    • Su, B.1    Wang, X.2    Lee, H.-G.3    Tabaton, M.4    Perry, G.5    Smith, M.A.6    Zhu, X.7
  • 33
    • 33746508651 scopus 로고    scopus 로고
    • Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms
    • DOI 10.1096/fj.05-5223com
    • Zhang Y.-J., Xu Y.-F., Liu Y.-H., Yin J., Li H.-A., Wang Q., Wang J.-Z., Peroxynitrite induces Alzheimer-like tau modifications and accumulation in rat brain and its underlying mechanisms. The FASEB Journal 2006 20 9 1431 1442 2-s2.0-33746508651 10.1096/fj.05-5223com (Pubitemid 44943851)
    • (2006) FASEB Journal , vol.20 , Issue.9 , pp. 1431-1442
    • Zhang, Y.-J.1    Xu, Y.-F.2    Liu, Y.-H.3    Yin, J.4    Li, H.-A.5    Wang, Q.6    Wang, J.-Z.7
  • 34
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • 2-s2.0-0024299370
    • Mahley R. W., Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988 240 4852 622 630 2-s2.0-0024299370
    • (1988) Science , vol.240 , Issue.4852 , pp. 622-630
    • Mahley, R.W.1
  • 35
    • 33746311471 scopus 로고    scopus 로고
    • Apolipoprotein E structure: Insights into function
    • DOI 10.1016/j.tibs.2006.06.008, PII S0968000406001708
    • Hatters D. M., Peters-Libeu C. A., Weisgraber K. H., Apolipoprotein E structure: insights into function. Trends in Biochemical Sciences 2006 31 8 445 454 2-s2.0-33746311471 10.1016/j.tibs.2006.06.008 (Pubitemid 44108662)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.8 , pp. 445-454
    • Hatters, D.M.1    Peters-Libeu, C.A.2    Weisgraber, K.H.3
  • 37
    • 0034719129 scopus 로고    scopus 로고
    • SDS-stable complex formation between native apolipoprotein E3 and β-amyloid peptides
    • DOI 10.1021/bi0017475
    • Munson G. W., Roher A. E., Kuo Y.-M., Gilligan S. M., Reardon C. A., Getz G. S., LaDu M. J., SDS-stable complex formation between native apolipoprotein E3 and β -amyloid peptides. Biochemistry 2000 39 51 16119 16124 2-s2.0-0034719129 10.1021/bi0017475 (Pubitemid 32038274)
    • (2000) Biochemistry , vol.39 , Issue.51 , pp. 16119-16124
    • Munson, G.W.1    Roher, A.E.2    Kuo, Y.-M.3    Gilligan, S.M.4    Reardon, C.A.5    Getz, G.S.6    LaDu, M.J.7
  • 38
    • 0034746840 scopus 로고    scopus 로고
    • Role of apoE/Aβ interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy
    • DOI 10.1385/JMN:17:2:147
    • Holtzman D. M., Role of apoE/A β interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy. Journal of Molecular Neuroscience 2001 17 2 147 155 2-s2.0-0034746840 10.1385/JMN:17:2:147 (Pubitemid 33063519)
    • (2001) Journal of Molecular Neuroscience , vol.17 , Issue.2 , pp. 147-155
    • Holtzman, D.M.1
  • 41
    • 0028059454 scopus 로고
    • Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice
    • DOI 10.1006/bbrc.1994.1883
    • Hayek T., Oiknine J., Brook J. G., Aviram M., Increased plasma and lipoprotein lipid peroxidation in apo E-deficient mice. Biochemical and Biophysical Research Communications 1994 201 3 1567 1574 2-s2.0-0028059454 10.1006/bbrc.1994.1883 (Pubitemid 24234268)
    • (1994) Biochemical and Biophysical Research Communications , vol.201 , Issue.3 , pp. 1567-1574
    • Hayek, T.1    Oiknine, J.2    Brook, J.G.3    Aviram, M.4
  • 42
    • 0037108213 scopus 로고    scopus 로고
    • Apolipoprotein e deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue
    • 2-s2.0-0037108213 10.1016/S0891-5849(02)01001-8
    • Shea T. B., Rogers E., Ashline D., Ortiz D., Sheu M.-S., Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue. Free Radical Biology and Medicine 2002 33 8 1115 1120 2-s2.0-0037108213 10.1016/S0891-5849(02)01001-8
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.8 , pp. 1115-1120
    • Shea, T.B.1    Rogers, E.2    Ashline, D.3    Ortiz, D.4    Sheu, M.-S.5
  • 43
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides
    • DOI 10.1038/ng0996-55
    • Miyata M., Smith J. D., Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β -amyloid peptides. Nature Genetics 1996 14 1 55 61 2-s2.0-0029765553 10.1038/ng0996-55 (Pubitemid 26301547)
    • (1996) Nature Genetics , vol.14 , Issue.1 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 44
    • 47049127899 scopus 로고    scopus 로고
    • Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein e genotypes in Alzheimer disease
    • 2-s2.0-47049127899 10.1016/j.clinbiochem.2008.05.001
    • Kharrazi H., Vaisi-Raygani A., Rahimi Z., Tavilani H., Aminian M., Pourmotabbed T., Association between enzymatic and non-enzymatic antioxidant defense mechanism with apolipoprotein E genotypes in Alzheimer disease. Clinical Biochemistry 2008 41 12 932 936 2-s2.0-47049127899 10.1016/j.clinbiochem.2008. 05.001
    • (2008) Clinical Biochemistry , vol.41 , Issue.12 , pp. 932-936
    • Kharrazi, H.1    Vaisi-Raygani, A.2    Rahimi, Z.3    Tavilani, H.4    Aminian, M.5    Pourmotabbed, T.6
  • 45
    • 0037016321 scopus 로고    scopus 로고
    • Apolipoprotein E modulates Alzheimer's Aβ(1-42)-induced oxidative damage to synaptosomes in an allele-specific manner
    • DOI 10.1016/S0006-8993(01)03228-0, PII S0006899301032280
    • Lauderback C. M., Kanski J., Hackett J. M., Maeda N., Kindy M. S., Butterfield D. A., Apolipoprotein E modulates Alzheimer's A β (1-42)-induced oxidative damage to synaptosomes in an allele-specific manner. Brain Research 2002 924 1 90 97 2-s2.0-0037016321 10.1016/S0006-8993(01)03228-0 (Pubitemid 34017468)
    • (2002) Brain Research , vol.924 , Issue.1 , pp. 90-97
    • Lauderback, C.M.1    Kanski, J.2    Hackett, J.M.3    Maeda, N.4    Kindy, M.S.5    Butterfield D.Allan6
  • 47
    • 17844394677 scopus 로고    scopus 로고
    • N-acteyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency
    • 2-s2.0-17844394677
    • Tchantchou F., Graves M., Rogers E., Ortiz D., Shea T. B., N-acteyl cysteine alleviates oxidative damage to central nervous system of ApoE-deficient mice following folate and vitamin E-deficiency. Journal of Alzheimer's Disease 2005 7 2 135 180 2-s2.0-17844394677
    • (2005) Journal of Alzheimer's Disease , vol.7 , Issue.2 , pp. 135-180
    • Tchantchou, F.1    Graves, M.2    Rogers, E.3    Ortiz, D.4    Shea, T.B.5
  • 48
    • 38149125627 scopus 로고    scopus 로고
    • Effect of apoE genotype and vitamin e on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice
    • 2-s2.0-38149125627
    • Huebbe P., Jofre-Monseny L., Boesch-Saadatmandi C., Minihane A.-M., Rimbach G., Effect of apoE genotype and vitamin E on biomarkers of oxidative stress in cultured neuronal cells and the brain of targeted replacement mice. Journal of Physiology and Pharmacology 2007 58 4 683 698 2-s2.0-38149125627
    • (2007) Journal of Physiology and Pharmacology , vol.58 , Issue.4 , pp. 683-698
    • Huebbe, P.1    Jofre-Monseny, L.2    Boesch-Saadatmandi, C.3    Minihane, A.-M.4    Rimbach, G.5
  • 49
    • 84862870271 scopus 로고    scopus 로고
    • The axonal transport of mitochondria
    • Saxton W. M., Hollenbeck P. J., The axonal transport of mitochondria. Journal of Cell Science 2012 125 9 2095 2104
    • (2012) Journal of Cell Science , vol.125 , Issue.9 , pp. 2095-2104
    • Saxton, W.M.1    Hollenbeck, P.J.2
  • 50
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • DOI 10.1016/j.cell.2004.11.003, PII S0092867404010451
    • Li Z., Okamoto K.-I., Hayashi Y., Sheng M., The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 2004 119 6 873 887 2-s2.0-10944269186 10.1016/j.cell.2004.11.003 (Pubitemid 40017692)
    • (2004) Cell , vol.119 , Issue.6 , pp. 873-887
    • Li, Z.1    Okamoto, K.-I.2    Hayashi, Y.3    Sheng, M.4
  • 53
    • 84876732347 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain Complexes i and IV are impaired by beta-amyloid via direct interaction and through Complex I-dependent ROS production, respectively
    • Bobba A., Amadoro G., Valenti D., Corsetti V., Lassandro R., Atlante A., Mitochondrial respiratory chain Complexes I and IV are impaired by beta-amyloid via direct interaction and through Complex I-dependent ROS production, respectively. Mitochondrion 2013 13 4 298 311
    • (2013) Mitochondrion , vol.13 , Issue.4 , pp. 298-311
    • Bobba, A.1    Amadoro, G.2    Valenti, D.3    Corsetti, V.4    Lassandro, R.5    Atlante, A.6
  • 54
    • 81255190781 scopus 로고    scopus 로고
    • Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
    • 2-s2.0-81255190781 10.1093/hmg/ddr381
    • Calkins M. J., Manczak M., Mao P., Shirendeb U., Reddy P. H., Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Human Molecular Genetics 2011 20 23 4515 4529 2-s2.0-81255190781 10.1093/hmg/ddr381
    • (2011) Human Molecular Genetics , vol.20 , Issue.23 , pp. 4515-4529
    • Calkins, M.J.1    Manczak, M.2    Mao, P.3    Shirendeb, U.4    Reddy, P.H.5
  • 55
    • 1542318096 scopus 로고    scopus 로고
    • Initiation of Neuronal Damage by Complex I Deficiency and Oxidative Stress in Parkinson's Disease
    • DOI 10.1023/B:NERE.0000014827.94562.4b
    • Tretter L., Sipos I., Adam-Vizi V., Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease. Neurochemical Research 2004 29 3 569 577 2-s2.0-1542318096 10.1023/B:NERE.0000014827.94562.4b (Pubitemid 38295007)
    • (2004) Neurochemical Research , vol.29 , Issue.3 , pp. 569-577
    • Tretter, L.1    Sipos, I.2    Adam-Vizi, V.3
  • 56
    • 0032589515 scopus 로고    scopus 로고
    • 2+- stimulated generation of reactive oxygen species by the respiratory chain
    • DOI 10.1021/bi9828674
    • 2+- stimulated generation of reactive oxygen species by the respiratory chain. Biochemistry 1999 38 40 13279 13287 2-s2.0-0032589515 10.1021/bi9828674 (Pubitemid 29477442)
    • (1999) Biochemistry , vol.38 , Issue.40 , pp. 13279-13287
    • Grijalba, M.T.1    Vercesi, A.E.2    Schreier, S.3
  • 57
    • 67650732998 scopus 로고    scopus 로고
    • Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
    • 2-s2.0-67650732998 10.1523/JNEUROSCI.1357-09.2009
    • Wang X., Su B., Lee H.-G., Li X., Perry G., Smith M. A., Zhu X., Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. Journal of Neuroscience 2009 29 28 9090 9103 2-s2.0-67650732998 10.1523/JNEUROSCI.1357-09. 2009
    • (2009) Journal of Neuroscience , vol.29 , Issue.28 , pp. 9090-9103
    • Wang, X.1    Su, B.2    Lee, H.-G.3    Li, X.4    Perry, G.5    Smith, M.A.6    Zhu, X.7
  • 58
    • 79958721260 scopus 로고    scopus 로고
    • Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: Implications for neuronal damage
    • 2-s2.0-79958721260 10.1093/hmg/ddr139
    • Manczak M., Calkins M. J., Reddy P. H., Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Human Molecular Genetics 2011 20 13 2495 2509 2-s2.0-79958721260 10.1093/hmg/ddr139
    • (2011) Human Molecular Genetics , vol.20 , Issue.13 , pp. 2495-2509
    • Manczak, M.1    Calkins, M.J.2    Reddy, P.H.3
  • 59
    • 0024215686 scopus 로고
    • Relationship between synaptogenesis and cytochrome oxidase activity in Purkinje cells of the developing rat cerebellum
    • DOI 10.1002/cne.902770202
    • Mjaatvedt A. E., Wong-Riley M. T. T., Relationship between synaptogenesis and cytochrome oxidase activity in Purkinje cells of the developing rat cerebellum. Journal of Comparative Neurology 1988 277 2 155 182 2-s2.0-0024215686 (Pubitemid 19002129)
    • (1988) Journal of Comparative Neurology , vol.277 , Issue.2 , pp. 155-182
    • Mjaatvedt, A.E.1    Wong-Riley, M.T.T.2
  • 60
    • 53049099984 scopus 로고    scopus 로고
    • Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress
    • 2-s2.0-53049099984 10.1016/j.mito.2008.06.001
    • Jendrach M., Mai S., Pohl S., Vöth M., Bereiter-Hahn J., Short- and long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress. Mitochondrion 2008 8 4 293 304 2-s2.0-53049099984 10.1016/j.mito.2008.06.001
    • (2008) Mitochondrion , vol.8 , Issue.4 , pp. 293-304
    • Jendrach, M.1    Mai, S.2    Pohl, S.3    Vöth, M.4    Bereiter-Hahn, J.5
  • 61
    • 0036460110 scopus 로고    scopus 로고
    • Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility
    • DOI 10.1046/j.1460-9568.2002.02001.x
    • Jost C. R., van der Zee C. E. E. M., In 't Zandt H. J. A., Oerlemans F., Verheij M., Streijger F., Fransen J., Heerschap A., Cools A. R., Wieringa B., Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility. European Journal of Neuroscience 2002 15 10 1692 1706 2-s2.0-0036460110 10.1046/j.1460-9568.2002.02001.x (Pubitemid 35471925)
    • (2002) European Journal of Neuroscience , vol.15 , Issue.10 , pp. 1692-1706
    • Jost, C.R.1    Van Der Zee, C.E.E.M.2    In 't Zandt, H.J.A.3    Oerlemans, F.4    Verheij, M.5    Streijger, F.6    Fransen, J.7    Heerschap, A.8    Cools, A.R.9    Wieringa, B.10
  • 62
    • 11444261073 scopus 로고    scopus 로고
    • Structural and behavioural consequences of double deficiency for creatine kinases BCK and UbCKmit
    • DOI 10.1016/j.bbr.2004.07.002, PII S016643280400258X
    • Streijger F., Oerlemans F., Ellenbroek B. A., Jost C. R., Wieringa B., van der Zee C. E. E. M., Structural and behavioural consequences of double deficiency for creatine kinases BCK and UbCKmit. Behavioural Brain Research 2005 157 2 219 234 2-s2.0-11444261073 10.1016/j.bbr.2004.07.002 (Pubitemid 40082565)
    • (2005) Behavioural Brain Research , vol.157 , Issue.2 , pp. 219-234
    • Streijger, F.1    Oerlemans, F.2    Ellenbroek, B.A.3    Jost, C.R.4    Wieringa, B.5    Van Der Zee, C.E.E.M.6
  • 63
    • 33646340668 scopus 로고    scopus 로고
    • The creatine kinase/creatine connection to alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits
    • DOI 10.1155/JBB/2006/35936, PII S1110724306359360
    • Bürklen T. S., Schlattner U., Homayouni R., Gough K., Rak M., Szeghalmi A., Wallimann T., The creatine kinase/creatine connection to alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits. Journal of Biomedicine and Biotechnology 2006 2006 11 2-s2.0-33646340668 10.1155/JBB/2006/35936 35936 (Pubitemid 43672669)
    • (2006) Journal of Biomedicine and Biotechnology , vol.2006 , pp. 35936
    • Burklen, T.S.1    Schlattner, U.2    Homayouni, R.3    Gough, K.4    Rak, M.5    Szeghalmi, A.6    Wallimann, T.7
  • 64
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer's disease
    • Iadecola C., Neurovascular regulation in the normal brain and in Alzheimer's disease. Nature Reviews Neuroscience 2004 5 5 347 360 2-s2.0-2342614850 (Pubitemid 38568496)
    • (2004) Nature Reviews Neuroscience , vol.5 , Issue.5 , pp. 347-360
    • Iadecola, C.1
  • 65
    • 14044258771 scopus 로고    scopus 로고
    • NADPH oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid β peptide
    • DOI 10.1523/JNEUROSCI.5207-04.2005
    • Park L., Anrather J., Zhou P., Frys K., Pitstick R., Younkin S., Carlson G. A., Iadecola C., NADPH oxidase-derived reactive oxygen species mediate the cerebrovascular dysfunction induced by the amyloid β peptide. Journal of Neuroscience 2005 25 7 1769 1777 2-s2.0-14044258771 10.1523/JNEUROSCI.5207-04. 2005 (Pubitemid 40279282)
    • (2005) Journal of Neuroscience , vol.25 , Issue.7 , pp. 1769-1777
    • Park, L.1    Anrather, J.2    Zhou, P.3    Frys, K.4    Pitstick, R.5    Younkin, S.6    Carlson, G.A.7    Iadecola, C.8
  • 67
    • 84867842594 scopus 로고    scopus 로고
    • Vascular factors and epigenetic modifications in the pathogenesis of Alzheimer's disease
    • Leszek J., Sochocka M., Gasiorowski K., Vascular factors and epigenetic modifications in the pathogenesis of Alzheimer's disease. Journal of the Neurological Sciences 2012 323 1-2 25 32
    • (2012) Journal of the Neurological Sciences , vol.323 , Issue.1-2 , pp. 25-32
    • Leszek, J.1    Sochocka, M.2    Gasiorowski, K.3
  • 68
    • 0029619651 scopus 로고
    • The pathogenesis of cardiovascular disease: Role of the endothelium as a target and mediator
    • DOI 10.1016/0021-9150(95)05667-X
    • Luscher T. F., Noll G., The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator. Atherosclerosis 1995 118 S81 S90 2-s2.0-0029619651 10.1016/0021-9150(95)05667-X (Pubitemid 26027336)
    • (1995) Atherosclerosis , vol.118 , Issue.SUPPL.
    • Luscher, T.F.1    Noll, G.2
  • 69
    • 84866734226 scopus 로고    scopus 로고
    • Vascular cognitive impairment and Alzheimer's disease: Role of cerebral hypoperfusion and oxidative stress
    • Kim H. A., Miller A. A., Drummond G. R., Vascular cognitive impairment and Alzheimer's disease: role of cerebral hypoperfusion and oxidative stress. Naunyn-Schmiedeberg's Archives of Pharmacology 2012 385 10 953 959
    • (2012) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.385 , Issue.10 , pp. 953-959
    • Kim, H.A.1    Miller, A.A.2    Drummond, G.R.3
  • 70
    • 84877030960 scopus 로고    scopus 로고
    • Vascular oxidative stress and mitochondrial failure in the pathobiology of Alzheimer's disease: New approach to therapy
    • Sochocka M., Koutsouraki E. S., Gasiorowski K., Leszek J., Vascular oxidative stress and mitochondrial failure in the pathobiology of Alzheimer's disease: new approach to therapy. CNS and Neurological Disorders 2013 12 6 870 881
    • (2013) CNS and Neurological Disorders , vol.12 , Issue.6 , pp. 870-881
    • Sochocka, M.1    Koutsouraki, E.S.2    Gasiorowski, K.3    Leszek, J.4
  • 71
    • 68949152521 scopus 로고    scopus 로고
    • Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease
    • 2-s2.0-68949152521 10.1016/j.biocel.2009.03.015
    • Aliev G., Palacios H. H., Walrafen B., Lipsitt A. E., Obrenovich M. E., Morales L., Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease. International Journal of Biochemistry and Cell Biology 2009 41 10 1989 2004 2-s2.0-68949152521 10.1016/j.biocel.2009.03.015
    • (2009) International Journal of Biochemistry and Cell Biology , vol.41 , Issue.10 , pp. 1989-2004
    • Aliev, G.1    Palacios, H.H.2    Walrafen, B.3    Lipsitt, A.E.4    Obrenovich, M.E.5    Morales, L.6
  • 72
    • 84882801362 scopus 로고    scopus 로고
    • Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia
    • Akinyemi R. O., Mukaetova-Ladinska E. B., Attems J., Ihara M., Kalaria R. N., Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia. Current Alzheimer Research 2013 10 6 642 653
    • (2013) Current Alzheimer Research , vol.10 , Issue.6 , pp. 642-653
    • Akinyemi, R.O.1    Mukaetova-Ladinska, E.B.2    Attems, J.3    Ihara, M.4    Kalaria, R.N.5
  • 74
    • 34047121150 scopus 로고    scopus 로고
    • Renin-angiotensin system and cardiovascular risk
    • DOI 10.1016/S0140-6736(07)60242-6, PII S0140673607602426
    • Schmieder R. E., Hilgers K. F., Schlaich M. P., Schmidt B. M., Renin-angiotensin system and cardiovascular risk. The Lancet 2007 369 9568 1208 1219 2-s2.0-34047121150 10.1016/S0140-6736(07)60242-6 (Pubitemid 46527856)
    • (2007) Lancet , vol.369 , Issue.9568 , pp. 1208-1219
    • Schmieder, R.E.1    Hilgers, K.F.2    Schlaich, M.P.3    Schmidt, B.M.4
  • 75
    • 84866788499 scopus 로고    scopus 로고
    • Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders
    • Saavedra J. M., Angiotensin II AT(1) receptor blockers as treatments for inflammatory brain disorders. Clinical Science 2012 123 10 567 590
    • (2012) Clinical Science , vol.123 , Issue.10 , pp. 567-590
    • Saavedra, J.M.1
  • 76
    • 84872150887 scopus 로고    scopus 로고
    • Roles of brain angiotensin II in cognitive function and dementia
    • 169649 10.1155/2012/169649
    • Mogi M., Iwanami J., Horiuchi M., Roles of brain angiotensin II in cognitive function and dementia. International Journal of Hypertension 2012 2012 7 169649 10.1155/2012/169649
    • (2012) International Journal of Hypertension , vol.2012 , pp. 7
    • Mogi, M.1    Iwanami, J.2    Horiuchi, M.3
  • 77
    • 33646710114 scopus 로고    scopus 로고
    • Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals
    • DOI 10.1161/01.ATV.0000205849.22807.6e, PII 0004360520060400000023
    • Girouard H., Park L., Anrather J., Zhou P., Iadecola C., Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals. Arteriosclerosis, Thrombosis, and Vascular Biology 2006 26 4 826 832 2-s2.0-33646710114 10.1161/01.ATV.0000205849.22807.6e (Pubitemid 43732158)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.4 , pp. 826-832
    • Girouard, H.1    Park, L.2    Anrather, J.3    Zhou, P.4    Iadecola, C.5
  • 78
    • 8844227341 scopus 로고    scopus 로고
    • Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
    • DOI 10.1161/01.RES.0000148637.85595.c5
    • Kazama K., Anrather J., Zhou P., Girouard H., Frys K., Milner T. A., Iadecola C., Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circulation Research 2004 95 10 1019 1026 2-s2.0-8844227341 10.1161/01.RES.0000148637.85595.c5 (Pubitemid 39532332)
    • (2004) Circulation Research , vol.95 , Issue.10 , pp. 1019-1026
    • Kazama, K.1    Anrather, J.2    Zhou, P.3    Girouard, H.4    Frys, K.5    Milner, T.A.6    Iadecola, C.7
  • 79
    • 78651313012 scopus 로고    scopus 로고
    • The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension
    • 2-s2.0-78651313012 10.1152/ajpheart.00679.2010
    • Capone C., Faraco G., Park L., Cao X., Davisson R. L., Iadecola C., The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. The American Journal of Physiology 2011 300 1 H397 H407 2-s2.0-78651313012 10.1152/ajpheart.00679.2010
    • (2011) The American Journal of Physiology , vol.300 , Issue.1
    • Capone, C.1    Faraco, G.2    Park, L.3    Cao, X.4    Davisson, R.L.5    Iadecola, C.6
  • 80
    • 74949131237 scopus 로고    scopus 로고
    • Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: Prospective cohort analysis
    • b5465 2-s2.0-74249110813 10.1136/bmj.b5465
    • Li N. C., Lee A., Whitmer R. A., Kivipelto M., Lawler E., Kazis L. E., Wolozin B., Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ 2010 340 b5465 2-s2.0-74249110813 10.1136/bmj.b5465
    • (2010) BMJ , vol.340
    • Li, N.C.1    Lee, A.2    Whitmer, R.A.3    Kivipelto, M.4    Lawler, E.5    Kazis, L.E.6    Wolozin, B.7
  • 81
    • 80054843547 scopus 로고    scopus 로고
    • Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias
    • 2-s2.0-80054843547 10.3233/JAD-2011-110347
    • Davies N. M., Kehoe P. G., Ben-Shlomo Y., Martin R. M., Associations of anti-hypertensive treatments with Alzheimer's disease, vascular dementia, and other dementias. Journal of Alzheimer's Disease 2011 26 4 699 708 2-s2.0-80054843547 10.3233/JAD-2011-110347
    • (2011) Journal of Alzheimer's Disease , vol.26 , Issue.4 , pp. 699-708
    • Davies, N.M.1    Kehoe, P.G.2    Ben-Shlomo, Y.3    Martin, R.M.4
  • 82
    • 73349097900 scopus 로고    scopus 로고
    • Angiotensin receptor blocker prevented β -amyloid-induced cognitive impairment associated with recovery of neurovascular coupling
    • 2-s2.0-73349097900 10.1161/HYPERTENSIONAHA.109.138586
    • Takeda S., Sato N., Takeuchi D., Kurinami H., Shinohara M., Niisato K., Kano M., Ogihara T., Rakugi H., Morishita R., Angiotensin receptor blocker prevented β -amyloid-induced cognitive impairment associated with recovery of neurovascular coupling. Hypertension 2009 54 6 1345 1352 2-s2.0-73349097900 10.1161/HYPERTENSIONAHA.109.138586
    • (2009) Hypertension , vol.54 , Issue.6 , pp. 1345-1352
    • Takeda, S.1    Sato, N.2    Takeuchi, D.3    Kurinami, H.4    Shinohara, M.5    Niisato, K.6    Kano, M.7    Ogihara, T.8    Rakugi, H.9    Morishita, R.10
  • 83
    • 70249088004 scopus 로고    scopus 로고
    • Effects of angiotensin II receptor blockers on dementia
    • 2-s2.0-70249088004 10.1038/hr.2009.110
    • Mogi M., Horiuchi M., Effects of angiotensin II receptor blockers on dementia. Hypertension Research 2009 32 9 738 740 2-s2.0-70249088004 10.1038/hr.2009.110
    • (2009) Hypertension Research , vol.32 , Issue.9 , pp. 738-740
    • Mogi, M.1    Horiuchi, M.2
  • 84
    • 3042730018 scopus 로고    scopus 로고
    • Alzheimer's disease is a vasocognopathy: A new term to describe its nature
    • DOI 10.1179/016164104225016254
    • de La Torre J. C., Alzheimer's disease is a vasocognopathy: a new term to describe its nature. Neurological Research 2004 26 5 517 524 2-s2.0-3042730018 10.1179/016164104225016254 (Pubitemid 38879234)
    • (2004) Neurological Research , vol.26 , Issue.5 , pp. 517-524
    • De La Torre, J.C.1
  • 85
    • 13544268809 scopus 로고    scopus 로고
    • Neurovascular mechanisms of Alzheimer's neurodegeneration
    • DOI 10.1016/j.tins.2005.02.001
    • Zlokovic B. V., Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends in Neurosciences 2005 28 4 202 208 2-s2.0-13544268809 10.1016/j.tins.2005.02.001 (Pubitemid 40445527)
    • (2005) Trends in Neurosciences , vol.28 , Issue.4 , pp. 202-208
    • Zlokovic, B.V.1
  • 86
    • 80052647359 scopus 로고    scopus 로고
    • Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease
    • 2-s2.0-80052647359 10.1096/fj.11-182873
    • Dong Y. F., Kataoka K., Tokutomi Y., Nako H., Nakamura T., Toyama K., Sueta D., Koibuchi N., Yamamoto E., Ogawa H., Kim-Mitsuyama S., Perindopril, a centrally active angiotensin-converting enzyme inhibitor, prevents cognitive impairment in mouse models of Alzheimer's disease. The FASEB Journal 2011 25 9 2911 2920 2-s2.0-80052647359 10.1096/fj.11-182873
    • (2011) The FASEB Journal , vol.25 , Issue.9 , pp. 2911-2920
    • Dong, Y.F.1    Kataoka, K.2    Tokutomi, Y.3    Nako, H.4    Nakamura, T.5    Toyama, K.6    Sueta, D.7    Koibuchi, N.8    Yamamoto, E.9    Ogawa, H.10    Kim-Mitsuyama, S.11
  • 87
    • 51049085039 scopus 로고    scopus 로고
    • Metabolic syndrome and alzheimer's disease: A link to a vascular hypothesis?
    • 2-s2.0-51049085039
    • Milionis H. J., Florentin M., Giannopoulos S., Metabolic syndrome and alzheimer's disease: a link to a vascular hypothesis? CNS Spectrums 2008 13 7 606 613 2-s2.0-51049085039
    • (2008) CNS Spectrums , vol.13 , Issue.7 , pp. 606-613
    • Milionis, H.J.1    Florentin, M.2    Giannopoulos, S.3
  • 88
    • 12244281810 scopus 로고    scopus 로고
    • Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid β-peptide (1-42) in a transgenic Caenorhabditis elegans model
    • DOI 10.1016/S0197-4580(02)00225-7
    • Drake J., Link C. D., Butterfield D. A., Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid β -peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiology of Aging 2003 24 3 415 420 2-s2.0-12244281810 10.1016/S0197-4580(02)00225-7 (Pubitemid 36210870)
    • (2003) Neurobiology of Aging , vol.24 , Issue.3 , pp. 415-420
    • Drake, J.1    Link, C.D.2    Butterfield, D.A.3
  • 89
    • 84883803181 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele
    • Qiu W. Q., Mwamburi M., Besser L. M., Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele. Journal of Alzheimer's Disease 2013 37 2 421 428
    • (2013) Journal of Alzheimer's Disease , vol.37 , Issue.2 , pp. 421-428
    • Qiu, W.Q.1    Mwamburi, M.2    Besser, L.M.3
  • 90
    • 84885593973 scopus 로고    scopus 로고
    • Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in beta-amyloid generation and Alzheimer's disease
    • Csiszar A., Tucsek Z., Toth P., Synergistic effects of hypertension and aging on cognitive function and hippocampal expression of genes involved in beta-amyloid generation and Alzheimer's disease. The American Journal of Physiology. Heart and Circulatory Physiology 2013 305 8 H1120 H1130
    • (2013) The American Journal of Physiology. Heart and Circulatory Physiology , vol.305 , Issue.8
    • Csiszar, A.1    Tucsek, Z.2    Toth, P.3
  • 91
    • 0036014989 scopus 로고    scopus 로고
    • Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: Implications for familial Alzheimer's disease
    • DOI 10.1023/A:1015560116208
    • LaFontaine M. A., Mattson M. P., Butterfield D. A., Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease. Neurochemical Research 2002 27 5 417 421 2-s2.0-0036014989 10.1023/A:1015560116208 (Pubitemid 34579349)
    • (2002) Neurochemical Research , vol.27 , Issue.5 , pp. 417-421
    • LaFontaine, M.A.1    Mattson, M.P.2    Butterfield, D.A.3
  • 92
    • 79960555700 scopus 로고    scopus 로고
    • Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis
    • 2-s2.0-79960555700 10.1111/j.1582-4934.2011.01318.x
    • Bosco D., Fava A., Plastino M., Montalcini T., Pujia A., Possible implications of insulin resistance and glucose metabolism in Alzheimer's disease pathogenesis. Journal of Cellular and Molecular Medicine 2011 15 9 1807 1821 2-s2.0-79960555700 10.1111/j.1582-4934.2011.01318.x
    • (2011) Journal of Cellular and Molecular Medicine , vol.15 , Issue.9 , pp. 1807-1821
    • Bosco, D.1    Fava, A.2    Plastino, M.3    Montalcini, T.4    Pujia, A.5
  • 94
    • 2342591369 scopus 로고    scopus 로고
    • Cerebrovascular Dysfunction in Zucker Obese Rats Is Mediated by Oxidative Stress and Protein Kinase C
    • DOI 10.2337/diabetes.53.5.1352
    • Erdös B., Snipes J. A., Miller A. W., Busija D. W., Cerebrovascular dysfunction in zucker obese rats is mediated by oxidative stress and protein kinase C. Diabetes 2004 53 5 1352 1359 2-s2.0-2342591369 10.2337/diabetes.53.5. 1352 (Pubitemid 38569023)
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1352-1359
    • Erdos, B.1    Snipes, J.A.2    Miller, A.W.3    Busija, D.W.4
  • 95
    • 48749102434 scopus 로고    scopus 로고
    • Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease
    • 2-s2.0-48749102434 10.1111/j.1471-4159.2008.05454.x
    • Pasinetti G. M., Eberstein J. A., Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease. Journal of Neurochemistry 2008 106 4 1503 1514 2-s2.0-48749102434 10.1111/j.1471-4159.2008.05454.x
    • (2008) Journal of Neurochemistry , vol.106 , Issue.4 , pp. 1503-1514
    • Pasinetti, G.M.1    Eberstein, J.A.2
  • 96
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in Alzheimer disease and vascular dementia: Two roads converged
    • 2-s2.0-62449142597 10.1001/archneurol.2009.27
    • Craft S., The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged. Archives of Neurology 2009 66 3 300 305 2-s2.0-62449142597 10.1001/archneurol.2009.27
    • (2009) Archives of Neurology , vol.66 , Issue.3 , pp. 300-305
    • Craft, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.