Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 51, 2005, Pages 18700-18705

  Ye, Shiming ^a   Huang, Yadong ^a,b,c,d   Müllendorff, Karin ^a   Dong, Liming ^b   Giedt, Gretchen ^b   Meng, Elaine C ^c   Cohen, Fred E ^c   Kuntz, Irwin D ^c   Weisgraber, Karl H ^a,b,c   Mahley, Robert W ^a,b,c,d  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Neurodegeneration

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E4; ARGININE; ISOPROTEIN; LIPID; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; SMALL INTERFERING RNA; THREONINE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RAT; RISK FACTOR; STRUCTURE ANALYSIS;

AMYLOID BETA-PROTEIN; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; CELL LINE, TUMOR; CHOLESTEROL; HUMANS; LDL-RECEPTOR RELATED PROTEINS; MODELS, MOLECULAR; NEURONS; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RATS;

ANIMALIA;

EID: 29444460533     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0508693102     Document Type: Article

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