Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis

Liver International

Volumn 34, Issue 3, 2014, Pages 427-437

  Ibrahim, Samar H ^a   Gores, Gregory J ^a   Hirsova, Petra ^a   Kirby, Michelle ^b   Miles, Lili ^b   Jaeschke, Anja ^c   Kohli, Rohit ^b  

^a MAYO CLINIC   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Fibrosis; Inflammation; JNK; Lipoapoptosis; Nonalcoholic fatty liver disease

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; INTERLEUKIN 1BETA; MESSENGER RNA; MIXED LINEAGE KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOPONTIN; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ALANINE AMINOTRANSFERASE; CARBOHYDRATE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CALORIC INTAKE; CARBOHYDRATE DIET; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FATTY LIVER; FIBROGENESIS; GLUCOSE TOLERANCE TEST; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INSULIN TOLERANCE TEST; LIPID DIET; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; STELLATE CELL; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WEIGHT GAIN; WILD TYPE; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; GENETICS; GENOTYPE; KNOCKOUT MOUSE; LIVER CIRRHOSIS; METABOLISM; PATHOLOGY;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; CARBOHYDRATES; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; GENOTYPE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER CIRRHOSIS; MALE; MAP KINASE KINASE KINASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NON-ALCOHOLIC FATTY LIVER DISEASE; TRIGLYCERIDES;

EID: 84893817138     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12353     Document Type: Article

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