메뉴 건너뛰기




Volumn 43, Issue 1, 2006, Pages 163-172

JNK1 but not JNK2 promotes the development of steatohepatitis in mice

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CHOLINE; INSULIN; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE 9; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ALANINE AMINOTRANSFERASE; INTERCELLULAR ADHESION MOLECULE 1;

EID: 33644813043     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20999     Document Type: Article
Times cited : (333)

References (42)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 2
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD Single Topic Conference
    • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference. HEPATOLOGY 2003;37:1202-1219.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 3
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 5
    • 0037369729 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 activity in nondiabetic patients with non-alcoholic steatohepatitis
    • Chalasani N, Gorski JC, Asghar MS, Asghar A, Foresman B, Hall SD, et al. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with non-alcoholic steatohepatitis. HEPATOLOGY 2003;37:544-550.
    • (2003) Hepatology , vol.37 , pp. 544-550
    • Chalasani, N.1    Gorski, J.C.2    Asghar, M.S.3    Asghar, A.4    Foresman, B.5    Hall, S.D.6
  • 6
    • 0031962151 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
    • Weltman MD, Farrell GC, Hall P, Ingelman-Sundberg M, Liddle C. Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis. HEPATOLOGY 1998;27:128-133.
    • (1998) Hepatology , vol.27 , pp. 128-133
    • Weltman, M.D.1    Farrell, G.C.2    Hall, P.3    Ingelman-Sundberg, M.4    Liddle, C.5
  • 8
    • 2342591361 scopus 로고    scopus 로고
    • Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis
    • Laurent A, Nicco C, Tran VN, Borderie D, Chereau C, Conti F, et al. Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis. HEPATOLOGY 2004;39:1277-1285.
    • (2004) Hepatology , vol.39 , pp. 1277-1285
    • Laurent, A.1    Nicco, C.2    Tran, V.N.3    Borderie, D.4    Chereau, C.5    Conti, F.6
  • 9
    • 3042820278 scopus 로고    scopus 로고
    • Liver injury in the setting of steatosis: Crosstalk between adipokine and cytokine
    • Czaja MJ. Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine. HEPATOLOGY 2004;40:19-22.
    • (2004) Hepatology , vol.40 , pp. 19-22
    • Czaja, M.J.1
  • 10
    • 0036086898 scopus 로고    scopus 로고
    • Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-α
    • Liu H, Jones BE, Bradham C, Czaja MJ. Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-α. Am J Physiol Gastrointest Liver Physiol 2002;282:G257-G266.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.282
    • Liu, H.1    Jones, B.E.2    Bradham, C.3    Czaja, M.J.4
  • 11
    • 0034881391 scopus 로고    scopus 로고
    • The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 2001;7:947-953.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 12
    • 3042699353 scopus 로고    scopus 로고
    • Adiponectin protects LPS-induced liver injury through modulation of TNF-α in KK-Ay obese mice
    • Masaki T, Chiba S, Tatsukawa H, Yasuda T, Noguchi H, Seike M, et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-α in KK-Ay obese mice. HEPATOLOGY 2004;40:177-184.
    • (2004) Hepatology , vol.40 , pp. 177-184
    • Masaki, T.1    Chiba, S.2    Tatsukawa, H.3    Yasuda, T.4    Noguchi, H.5    Seike, M.6
  • 16
    • 0037910211 scopus 로고    scopus 로고
    • The future of GI and liver research: Editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death
    • Czaja MJ. The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death. Am J Physiol Gastrointest Liver Physiol 2003;284:G875-G879.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Czaja, M.J.1
  • 17
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000;103:239-252.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 18
    • 0036009411 scopus 로고    scopus 로고
    • NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
    • Liu H, Lo CR, Czaja MJ. NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. HEPATOLOGY 2002;35:772-778.
    • (2002) Hepatology , vol.35 , pp. 772-778
    • Liu, H.1    Lo, C.R.2    Czaja, M.J.3
  • 20
  • 21
    • 8644286664 scopus 로고    scopus 로고
    • Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-α expression
    • Wang WH, Gregori G, Hullinger RL, Andrisani OM. Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-α expression. Mol Cell Biol 2004;24:10352-10365.
    • (2004) Mol Cell Biol , vol.24 , pp. 10352-10365
    • Wang, W.H.1    Gregori, G.2    Hullinger, R.L.3    Andrisani, O.M.4
  • 23
    • 15444375341 scopus 로고    scopus 로고
    • Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
    • Schattenberg JM, Wang Y, Singh R, Rigoli RM, Czaja MJ. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. J Biol Chem 2005;280:9887-9894.
    • (2005) J Biol Chem , vol.280 , pp. 9887-9894
    • Schattenberg, J.M.1    Wang, Y.2    Singh, R.3    Rigoli, R.M.4    Czaja, M.J.5
  • 24
    • 0034092716 scopus 로고    scopus 로고
    • CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    • Leclercq IA, Farrell GC, Field J, Bell DR, Gonzalez FJ, Robertson GR. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis. J Clin Invest 2000; 105:1067-1075.
    • (2000) J Clin Invest , vol.105 , pp. 1067-1075
    • Leclercq, I.A.1    Farrell, G.C.2    Field, J.3    Bell, D.R.4    Gonzalez, F.J.5    Robertson, G.R.6
  • 27
    • 0346689994 scopus 로고    scopus 로고
    • The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
    • Rinella ME, Green RM. The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance. J Hepatol 2004;40:47-51.
    • (2004) J Hepatol , vol.40 , pp. 47-51
    • Rinella, M.E.1    Green, R.M.2
  • 28
    • 4444341881 scopus 로고    scopus 로고
    • Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation
    • Sabapathy K, Hochedlinger K, Nam SY, Bauer A, Karin M, Wagner EF. Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation. Mol Cell 2004;15:713-725.
    • (2004) Mol Cell , vol.15 , pp. 713-725
    • Sabapathy, K.1    Hochedlinger, K.2    Nam, S.Y.3    Bauer, A.4    Karin, M.5    Wagner, E.F.6
  • 29
    • 9644295733 scopus 로고    scopus 로고
    • Curcumin inhibits NF-κB activation and reduces the severity of experimental steatohepatitis in mice
    • Leclercq IA, Farrell GC, Sempoux C, dela Pena A, Horsmans Y. Curcumin inhibits NF-κB activation and reduces the severity of experimental steatohepatitis in mice. J Hepatol 2004;41:926-934.
    • (2004) J Hepatol , vol.41 , pp. 926-934
    • Leclercq, I.A.1    Farrell, G.C.2    Sempoux, C.3    Dela Pena, A.4    Horsmans, Y.5
  • 30
    • 0042165989 scopus 로고    scopus 로고
    • Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis
    • Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, et al. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis. Gastroenterology 2003;125:437-443.
    • (2003) Gastroenterology , vol.125 , pp. 437-443
    • Feldstein, A.E.1    Canbay, A.2    Angulo, P.3    Taniai, M.4    Burgart, L.J.5    Lindor, K.D.6
  • 32
    • 0031825424 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase cascades as regulators of stress responses
    • Karin M. Mitogen-activated protein kinase cascades as regulators of stress responses. Ann N Y Acad Sci 1998;851:139-146.
    • (1998) Ann N Y Acad Sci , vol.851 , pp. 139-146
    • Karin, M.1
  • 33
    • 12144291516 scopus 로고    scopus 로고
    • JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways
    • Dietrich N, Thastrup J, Holmberg C, Gyrd-Hansen M, Fehrenbacher N, Lademann U, et al. JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways. Cell Death Differ 2004;11:301-313.
    • (2004) Cell Death Differ , vol.11 , pp. 301-313
    • Dietrich, N.1    Thastrup, J.2    Holmberg, C.3    Gyrd-Hansen, M.4    Fehrenbacher, N.5    Lademann, U.6
  • 34
    • 11244280883 scopus 로고    scopus 로고
    • JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine
    • Eminel S, Klettner A, Roemer L, Herdegen T, Waetzig V. JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine. J Biol Chem 2004;279:55385-55392.
    • (2004) J Biol Chem , vol.279 , pp. 55385-55392
    • Eminel, S.1    Klettner, A.2    Roemer, L.3    Herdegen, T.4    Waetzig, V.5
  • 35
    • 10044247350 scopus 로고    scopus 로고
    • c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis
    • Liu J, Minemoto Y, Lin A. c-Jun N-terminal protein kinase 1 (JNK1), but not JNK2, is essential for tumor necrosis factor alpha-induced c-Jun kinase activation and apoptosis. Mol Cell Biol 2004;24:10844-10856.
    • (2004) Mol Cell Biol , vol.24 , pp. 10844-10856
    • Liu, J.1    Minemoto, Y.2    Lin, A.3
  • 36
    • 0344496062 scopus 로고    scopus 로고
    • IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha
    • Maeda S, Chang L, Li ZW, Luo JL, Leffert H, Karin M. IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha. Immunity 2003;19:725-737.
    • (2003) Immunity , vol.19 , pp. 725-737
    • Maeda, S.1    Chang, L.2    Li, Z.W.3    Luo, J.L.4    Leffert, H.5    Karin, M.6
  • 37
    • 0037192809 scopus 로고    scopus 로고
    • The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase
    • He T, Stepulak A, Holmstrom TH, Omary MB, Eriksson JE. The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase. J Biol Chem 2002;277:10767-10774.
    • (2002) J Biol Chem , vol.277 , pp. 10767-10774
    • He, T.1    Stepulak, A.2    Holmstrom, T.H.3    Omary, M.B.4    Eriksson, J.E.5
  • 38
    • 0038580372 scopus 로고    scopus 로고
    • Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling
    • Czaja MJ, Liu H, Wang Y. Oxidant-induced hepatocyte injury from menadione is regulated by ERK and AP-1 signaling. HEPATOLOGY 2003;37:1405-1413.
    • (2003) Hepatology , vol.37 , pp. 1405-1413
    • Czaja, M.J.1    Liu, H.2    Wang, Y.3
  • 39
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 2002;110:1389-1398.
    • (2002) J Clin Invest , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 41
    • 0041302377 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
    • Xu A, Wang Y, Keshaw H, Xu LY, Lam KS, Cooper GJ. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest 2003;112:91-100.
    • (2003) J Clin Invest , vol.112 , pp. 91-100
    • Xu, A.1    Wang, Y.2    Keshaw, H.3    Xu, L.Y.4    Lam, K.S.5    Cooper, G.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.